Bibliometric analysis of publication trends in meningioma research (1992 - 2023).

The purpose of this study was providing an overview of meningioma research and its current situation. We conducted a bibliometric study of 14,027 articles and reviews on meningioma between January, 1992 to June, 2023 with the bibliometrix tool and VOSviewer. The distribution of authorship and collaboration patterns among countries, institutions, publications, and authors were analyzed.

Hierarchical in-out fusion for incomplete multimodal brain tumor segmentation.

Fusing multimodal data play a crucial role in accurate brain tumor segmentation network and clinical diagnosis, especially in scenarios with incomplete multimodal data. Existing multimodal fusion models usually perform intra-modal fusion at both shallow and deep layers relying predominantly on traditional attention fusion. Rather, using the same fusion strategy at different layers leads to critical issues, feature redundancy in shallow layers due to repetitive weighting of semantically similar low-level features, and progressive texture detail degradation in deeper layers caused by the inherent feature of deep neural networks.

HERC5 induces podocyte injury in LN by mediated IRF3 ISGylation to promote the production and overactivation of IFN-β in podocytes.

Podocytes may mediate local production of Type I interferon (IFN-I), which play a crucial role in the pathogenesis of lupus nephritis (LN). ISGylation is widely involved in the innate immune activation and IFN-I production. Here, we discovered that in patients with LN and pristane-induced model mouse the staining of HERC5, a E3 protein ligase in ISGylation, was markedly elevated in renal glomerulus and associated with podocyte injury.

Avenanthramide C from underutilized oat glumes exhibits dual anti-oxidant and anti-thrombotic effects in oxidative damage and thrombosis models.

Avenanthramides (Avns), particularly Avn-C, are unique phenolic compounds found in oats, known for their anti-oxidant and anti-inflammatory effects. This study evaluated Avn-C's bioactivity using oxidative damage models in HUVECs induced by -BOOH and thrombosis models in zebrafish induced by phenylhydrazine (PHZ). Avn-C exhibited potent antioxidant activity, with an IC value of 7.

[Effect of transcutaneous auricular vagus nerve stimulation combined with patient-controlled intravenous analgesia on postoperative pain in patients with total knee arthroplasty].

Objectives: To explore the effect of transcutaneous auricular vagus nerve stimulation (taVNS) combined with patient-controlled intravenous analgesia (PCIA) on postoperative pain in patients undergoing total knee arthroplasty (TKA).

Methods: A total of 140 patients with TKA were randomly divided into the taVNS group (=70, with 5 dropped-out) and the sham stimulation group (=70, with 6 dropped-out). The taVNS group received taVNS at the left ear conchae combined with PCIA treatment, while the sham stimulation group received sham taVNS at the left ear conchae combined with PCIA treatment.

Electronic Structure Tunable Metallosupramolecular Polymers as Bifunctional Electrocatalysts for Rechargeable Zn-Air Battery.

Metallosupramolecular polymers (MSPs) have shown great potential in the area of oxygen electrocatalysis due to their tunable electronic structure, and predictable coordination environment. Further exploration of structure-performance relationships of oxygen electrocatalysts is crucial for designing highly efficient catalysts. Herein, a strategy is proposed to prepare MSP-based bifunctional oxygen electrocatalysts with different oxygen electrocatalytic preferences (Co-AQ and Co-AN) by adjusting the electronic structure of organic linkers.

Functional MRI-based machine learning strategy for prediction of postoperative delirium in cardiac surgery patients: A secondary analysis of a prospective observational study.

Study Objective: Delirium is a common complication after cardiac surgery and is associated with poor prognosis. An effective delirium prediction model could identify high-risk patients who might benefit from targeted prevention strategies. We introduce machine learning models that employ resting-state functional MRI datasets obtained before surgery to predict postoperative delirium.

Natural compound PEITC inhibits gain of function of p53 mutants in cancer cells by switching YAP-binding partners between p53 and p73.

Phenethyl isothiocyanate (PEITC) derived from cruciferous vegetables has shown anticancer activities by modulating apoptosis, cell cycle arrest, drug-metabolizing enzymes and even preferentially restoring a 'WT-like' conformation to p53. But its molecular anti-cancer mechanisms are not well understood. Evidence shows that switching YAP-binding partners from pro-tumorigenic to pro-apoptotic proteins might hold great potential for the treatment of human cancers harboring mtp53.

Heat Tolerance Differences Between Hu Sheep and Hu Crossbred Sheep in Microbial Community Structure and Metabolism.

Background: The frequent occurrence of extreme temperature events causes significant economic losses to the livestock industry. Therefore, delving into the differences in the physiological and molecular mechanisms of heat stress across different sheep breeds is crucial for developing effective management and breeding strategies.

Methods: This study explores the differences in heat tolerance mechanisms between Hu sheep and Xinggao sheep by comparing their growth performance under normal and heat stress conditions, as well as examining the differences in physiological, biochemical, and antioxidant indicators related to heat tolerance, serum metabolomics, and gut microbiomics in a heat stress environment.

Targeting S100A9 attenuates social dysfunction by modulating neuroinflammation and myelination in a mouse model of autism.

Growing evidence supports a role for dysregulated neuroinflammation in autism. However, the underlying mechanisms of microglia-evoked neuroinflammation in the development of autistic phenotypes have not been elucidated. This study aimed to investigate the role and underlying mechanisms of microglial S100 calcium-binding protein A9 (S100A9) in autistic phenotypes.

Nickel-Catalyzed Cross-Electrophile Vinylation of α-Chloro Phosphonates.

Herein, we report a general and efficient Ni-catalyzed reductive cross-coupling reaction of substituted vinyl bromides and α-chloro phosphonates to access a set of α-vinyl phosphonates using zinc as the terminal reductant. This reaction exhibits broad substrate adaptability and good functional group tolerance, which allows to afford diverse compounds including structurally complex motifs from natural products and drugs. Furthermore, the practicality was certificated through the gram-scale and transformation experiments.

Observation of Topological Transition in Floquet Non-Hermitian Skin Effects in Silicon Photonics.

Non-Hermitian physics has greatly enriched our understanding of nonequilibrium phenomena and uncovered novel effects such as the non-Hermitian skin effect (NHSE) that has profoundly revolutionized the field. NHSE has been predicted in systems with nonreciprocal couplings which, however, are challenging to realize in experiments. Without nonreciprocal couplings, the NHSE can also emerge in systems with coexisting gauge fields and loss or gain (e.

Observation of dynamic non-Hermitian skin effects.

Non-Hermitian physics has emerged as a new paradigm that profoundly changes our understanding of non-equilibrium systems, introducing novel concepts such as exceptional points, spectral topology, and non-Hermitian skin effects (NHSEs). Most existing studies focus on non-Hermitian eigenstates, whereas dynamic properties have been discussed only recently, and the dynamic NHSEs are not yet confirmed in experiments. Here, we report the experimental observation of non-Hermitian skin dynamics using tunable one-dimensional nonreciprocal double-chain mechanical systems with glide-time symmetry.

Preoperative electroacupuncture versus sham electroacupuncture for the treatment of postoperative ileus after laparoscopic surgery for colorectal cancer in China: a study protocol for a multicentre, randomised, sham-controlled trial.

Introduction: Postoperative ileus (POI) is a postoperative complication that can cause lingering recovery after colorectal resection and a heavy healthcare system burden. Acupuncture aims to prevent postoperative complications, reduce the duration of POI, help recovery and shorten hospital stays. We hypothesise that preoperative electroacupuncture (EA) can promote POI recovery under the enhanced recovery after surgery protocol after laparoscopic surgery in patients with POI.

Identification and bioactivity evaluation of ring-opening and lactone forms of enterolactone from sheep fed flaxseed cake.

The previously undescribed lactone ring-opening enterolactone and its sulphate were purified along with the lactone counterparts from the urine of dairy sheep fed flaxseed cake. The structures were determined by NMR and MS analyses. The ring-opening and lactone forms underwent mutual transformation with changes in pH and milk could protect the lactone form.

Measuring entanglement entropy and its topological signature for phononic systems.

Entanglement entropy is a fundamental concept with rising importance in various fields ranging from quantum information science, black holes to materials science. In complex materials and systems, entanglement entropy provides insight into the collective degrees of freedom that underlie the systems' complex behaviours. As well-known predictions, the entanglement entropy exhibits area laws for systems with gapped excitations, whereas it follows the Gioev-Klich-Widom scaling law in gapless fermion systems.

High-adaptability refrigeration under extreme temperatures in summer enabled by metal-organic framework.

Extreme global climates in summer and frequent energy crises have led to an increasing demand for sustainable refrigeration; however, low-grade-thermal-energy-driven refrigeration at high ambient temperatures (≥ 40 °C) has rarely been studied. In this paper, we report a solar-driven efficient sorption refrigeration scheme for extreme ambient temperature in summer enabled by metal-organic framework-ammonia working pairs. MIL-101(Cr) consistently achieves an ammonia sorption capacity of 0.

Time-bin phase-encoding quantum key distribution using Sagnac-based optics and compatible electronics.

In this work, we present a new time-bin phase-encoding quantum key distribution (QKD), where the transmitter utilizes an inherently stable Sagnac-type interferometer, and has comparable electrical requirements to existing polarization or phase encoding schemes. This approach does not require intensity calibration and is insensitive to environmental disturbances, making it both flexible and high-performing. We conducted experiments with a compact QKD system to demonstrate the stability and secure key rate performance of the presented scheme.

Field test of quantum key distribution over aerial fiber based on simple and stable modulation.

We have developed a simple time-bin phase encoding quantum key distribution system, using the optical injection locking technique. This setup incorporates both the merits of simplicity and stability in encoding, and immunity to channel disturbance. We have demonstrated the field implementation of quantum key distribution over long-distance deployed aerial fiber automatically.

The Involvement of PGRMC1 Signaling in Cognitive Impairment Induced by Long-Term Clozapine Treatment in Rats.

Introduction: Progesterone receptor component 1 (PGRMC1) has been identified as a potential target in atypical antipsychotic drug-induced metabolic disturbances as well as neuroprotection in the central nervous system. In our study, we aimed to figure out the essential role of PGRMC1 signaling pathway underlying clozapine-induced cognitive impairment.

Methods: In male SD rats, we utilized recombinant adeno-associated viruses (BBB 2.

Inhibition of Brd4 alleviates osteoarthritis pain via suppression of neuroinflammation and activation of Nrf2-mediated antioxidant signalling.

Background And Purpose: Osteoarthritis (OA) pain remains a major clinical problem. It is urgent to identify novel therapeutic approaches for OA pain states. Bromodomain and extra-terminal (BET) protein inhibitors have robust anti-inflammatory effects in several pain models.

A meta-analysis comparing phenol treatment with surgical excision for pilonidal sinus.

Pilonidal sinus is a chronic condition characterized by inflammation, swelling, and pain in the sacrococcygeal region. In recent years, the rate of recurrence and wound complications in PSD remains high, and no treatment is universally accepted. This study aimed to compare the efficacy of phenol treatment with surgical excision treatment for PSD through a meta-analysis of controlled clinical trials.