Total Ionizing Dose Effect Simulation Modeling and Analysis for a DCAP Power Chip.

In this paper, a systematic study on performance degradation of a 0.18 μm BCD-process DCAP (Direct connection to the output CAPacitor) power chip under a total-dose radiation environment is carried out. The effects of total-dose radiation on the electrical characteristics of an MOS device are analyzed through device-level simulation.

Deterministic Double-Zero Media and Robust Wave Manipulation Using a Phononic Weyl Semimetal.

Double-zero media exhibit unparalleled impedance-independent wave manipulation properties. However, their reliance on accidental degeneracy makes them fragile to disturbances in structural geometry and material parameters. Here, we propose a topological approach to address this limitation.

From directional to omnidirectional: meta-devices for ultrabroadband sound absorption with near-causality-limit performance.

Traditional microperforated panel (MPP)-cavity absorbers and metamaterial-based sound absorbers rely on local resonances or multi-resonator designs, which limit their bandwidth, angular applicability, and ease of fabrication. Leveraging the reciprocity theorem and cavity resonances, we introduce a robust class of MPP absorbers, termed meta-MPPs, capable of achieving ultrabroadband near-total sound absorption across a range of 0.37 to 10 kHz.

Analysis and Optimization of Vertical NPN BJT for Strong Magnetic Fields.

This study systematically investigates the electrical characteristics of the vertical NPN bipolar junction transistor (VNPN BJT) in the strong magnetic field environment, focusing on analyzing the effects of magnetic field direction and intensity on key parameters such as terminal current and current gain (). The simulation results show that the magnetic field induces changes in the carrier distribution, thereby affecting the current transport path. Through the in-depth analysis of electron motion trajectories, potential distribution, and Hall voltage, this paper reveals the physical mechanisms behind the device's characteristic changes under the magnetic field and discovers that the inherent asymmetry of the BJT structure induces significant magnetic anisotropy effects.

Regulation of feeding behaviors by key sugar and bitter gustatory receptors in Helicoverpa armigera.

Background: Contact chemoreception plays a crucial role in host-plant recognition and acceptance of herbivorous insects; however, the mechanisms by which peripheral taste inputs regulate insect feeding remain unclear. The aim of this study is to clarify the ecological significance of sugar and bitter gustatory receptors (Grs) in the relationship between Helicoverpa armigera and its hostplants.

Results: Blocking the positive input via knocking out Gr10 only leads to an increase in palpating frequency, and decreases in both the feeding time and the amounts of larvae on palatable fruit substrates, thereby prolonging the larval stage.

Epidemiological and sociodemographic transitions in the global burden and risk factors for Alzheimer's disease and other dementias: a secondary analysis of GBD 2021.

Background: The study aimed to analyze the long-term trends in the global burden of Alzheimer's disease and other dementias(ADOD) in different regions, and assess the association between socio-demographic index(SDI) and disease burden.

Methods: We extracted data on the incidence, mortality, disability-adjusted life-years(DALYs), and age-standardized rates related to ADOD, as disease burden measures from 1990 to 2021. The joinpoint regression, quantile regression and restricted cubic splines were adopted to estimate the temporal trends and relationships with SDI.

Asthma and the risk of cardiovascular diseases and mortality: a meta-analysis of cohort studies.

Background: It has been shown that asthma is potentially linked to a higher risk of cardiovascular disease (CVD) and cardiovascular mortality (CVM).

Objectives: This study aims to systematically review and summarize epidemiological evidence on the relationship between asthma and these cardiovascular outcomes.

Design: Systematic review and meta-analysis.

Effects of Exogenous Phenolic Acids on Haustorium Induction of Seeds Based on Host Metabolome Data.

, a holoparasitic plant widely used in traditional Chinese medicine, relies on chemical signals from its host plant, , to initiate seed germination and haustorium induction. This study employed UPLC-MS/MS to analyze the root metabolites of . The results showed that 11 substances such as phenolic acids, flavonoids, and alkaloids were mainly contained in the roots of , among which phenolic acids accounted for the largest proportion, accounting for 18.

The Association between Allergic Diseases and Migraine: A Systematic Review and Meta-Analysis.

Introduction: This study aimed to systematically review and summarize epidemiological evidence on the relationship between allergic diseases and migraine outcomes.

Methods: This meta-analysis, which was registered with PROSPERO (CRD420250656492), employed data from PubMed, Embase, the Cochrane Library, and references from the studies included in the review. The search encompassed literature from the inception of these databases through February 24, 2025.

Characterization of T-Cell Receptor Profiles Predicts Survival Situation in Patients with Hepatocellular Carcinoma.

PurposeHepatocellular carcinoma (HCC) is the most common liver malignancy in the world, and tumor-infiltrating T cells have been shown to be closely related to the prognosis of HCC. This study investigated the potential and efficacy of T cell receptor (TCR) repertoire characterization as a biomarker for predicting survival differences.MethodsIn this study, we used high-throughput sequencing technology to systematically analyze the characteristics of TCR repertoires in tumor tissues obtained from 23 long-survivors and 8 short-survivors diagnosed with HCC.

Spermine delivered by ZIF90 nanoparticles alleviates atherosclerosis by targeted inhibition of macrophage ferroptosis in plaque.

Background: Nowadays, emerging evidence have suggested that the ferroptosis of macrophages could contribute to the progression of atherosclerosis (AS). Meanwhile, Spermine (Sp) could serve as an endogenous small molecule exhibiting a wide range of cardiovascular protective effects.

Methods: Zeolitic imidazolate framework-90 (ZIF90) nanoparticles were synthesized and utilized to create a novel delivery nanosystem encapsulated with Sp (CD16/32-ZIF90@Sp).

Emission factors and driving forces of provincial-level CO from electricity production and consumption in China from 2013 to 2020.

China's power sector has significant CO emissions, posing a substantial reduction challenge. Current emission reduction measures lack a systematic perspective, failing to adequately consider the primary drivers of emission growth associated with electricity consumption. Most existing driving force analyses overlook the role of electricity consumption and the complexities of the power transmission networks.

Quasi-Continuous Efficient Regulation of Single-Molecule Electronic Distribution.

The electronic distribution characteristics of molecules significantly influence the charge transport properties and the device performance of molecular electronic devices. These characteristics are closely related to subtle molecular structures, forming a formidable challenge for effective control. Here, a flexible crown ether moiety is integrated into the single-molecule junction, where its spatial structure can be regulated by an external electric field, enabling efficient tuning of the electronic characteristics.

Machine learning assisted plasmonic metascreen for enhanced broadband absorption in ultra-thin silicon films.

We propose and demonstrate a data-driven plasmonic metascreen that efficiently absorbs incident light over a wide spectral range in an ultra-thin silicon film. By embedding a double-nanoring silver array within a 20 nm ultrathin amorphous silicon (a-Si) layer, we achieve a significant enhancement of light absorption. This enhancement arises from the interaction between the resonant cavity modes and localized plasmonic modes, requiring precise tuning of plasmon resonances to match the absorption region of the silicon active layer.

Young Goji Fruit Volatiles Regulate the Oviposition Behavior and Chemosensory Gene Expression of Gravid Female .

The goji fruit fly, , is a major pest on the well-known medicinal plant . Dissecting the molecular mechanisms of the oviposition selection of regarding the host plant will help to identify new strategies for pest fly control. However, the molecular mechanism of chemical communication between the goji fruit fly and the host goji remains unclear.

All-Printed Microfluidic-Electrochemical Devices for Glucose Detection.

Free-standing capillary microfluidic channels were directly printed over printed electrodes using a particle/polymer mixture to fabricate microfluidic-electrochemical devices on polyethylene terephthalate (PET) films. Printed devices with no electrode modification were demonstrated to have the lowest limit of detection (LOD) of 7 μM for sensing glucose. The study shows that both a low polymer concentration in the mixture for printing the microfluidic channels and surface modification of the printed microfluidic channels using 3-aminopropyltrimethoxysilane can substantially boost the device's performance.

Prediction of Potential Distribution of in China under the Current and Future Climate Change.

is an important pest of , distributed in China, Korea, and Japan. In recent years, its damage to has become increasingly serious, causing enormous economic losses in China. This study and prediction of current and future suitable habitats for in China can provide an important reference for the monitoring, early warning, prevention, and control of the pest.

Local spatial and temporal relation discovery model based on attention mechanism for traffic forecasting.

Recognizing the evolution pattern of traffic condition and making accurate prediction play a vital role in intelligent transportation systems (ITS). With the massive increase of available traffic data, deep learning-based models have attracted considerable attention for their impressive performance in traffic forecasting. However, the majority of existing approaches neglect to model of asynchronously dynamic spatio-temporal correlation and fail to consider the impact of historical traffic data on future condition.

pH-responsive interface conversion efficient oral drug delivery platform for alleviating inflammatory bowel disease.

A key challenge for the effective treatment of intestinal diseases, including inflammatory bowel disease (IBD), is to develop an oral drug delivery system that can resist gastric acid erosion and efficiently release drugs after rapid entry into the intestine. In the present work, we developed oral composite nanoparticles (MSZ@PRHS) consisting of a rough mesoporous silica (RHS) loaded with Mesalazine (MSZ) and a CAP polymer membrane for targeted relief of inflammation in colitis. At the pH values of the simulated stomach and small intestine, the release rate of MSZ from MSZ@PRHS was low, while at the pH values of the simulated colon, the release rate of MSZ was high.

Selection and Validation of Reference Genes for Gene Expression in Loginova under Different Insecticide Stresses.

Insecticide resistance has long been a problem in crop pest control. is a major pest on the well-known medicinal plants L. Investigating insecticide resistance mechanisms of will help to identify pesticide reduction strategies to control the pest.

Identification and characterization of a novel associated with goji berry ( L.) crinkle disease.

Goji berry ( L.) is a traditional Chinese herbal medicinal plant that is extensively cultivated in the arid and semiarid regions of northwest China. In this study, a novel cytorhabdovirus, tentatively named "goji cytorhabdovirus A (GCVA)," was identified from the goji berry plant exhibiting leaf crinkle symptoms through high-throughput sequencing (HTS).

A Fast Simulation Method for Evaluating the Single-Event Effect in Aerospace Integrated Circuits.

With the continuous progress in integrated circuit technology, single-event effect (SEE) has become a key factor affecting the reliability of aerospace integrated circuits. Simulating fault injection using the computer simulation technique effectively reflects the SEE in aerospace integrated circuits. Due to various masking effects, only a small number of faults will result in errors; the traditional method of injecting one fault in one workload execution is inefficient.