Spatiotemporal changes in land use and identification of driving factor contributions in the Chengdu-Chongqing Economic Circle based on the random forest model.

As urbanization accelerates and ecological protection demands increase, the evolution of land use patterns and their driving mechanisms have become critical issues for regional sustainable development. This study focuses on the Chengdu-Chongqing Economic Circle as the research area, utilizing land use data from 2000 to 2022. By employing the land use transfer matrix, dynamic degree and stability index, standard deviational ellipse method, and the PLUS model integrated with the random forest algorithm, we systematically analyze the spatiotemporal evolution characteristics of land use and the contribution of driving factors.

Chain Length-Dependent Reverse Micelle Extraction of Prolamins From Baijiu Jiuzao: Synergistic Effects of Ethanol, Ionic Strength, and Chaotropic Agent.

This study investigated the chain length-dependent extraction efficiency of two cationic surfactants-dodecyltrimethylammonium bromide (C12, 12-carbon chain) and cetyltrimethylammonium bromide (C16, 16-carbon chain)-for reverse micelle extraction of prolamins from Baijiu Jiuzao (Chinese Baijiu distillers' grains). Although pH variations (4.0-9.

Skeletal editing of pyridines to aryldialdehydes.

Electron-deficient nitrogen-containing aromatic heterocycles, particularly pyridine derivatives, can be converted into all-carbon aromatic frameworks via the ANRORC (Addition of Nucleophile, Ring-Opening, and Ring-Closing) skeletal editing process, providing a convenient tool for molecular diversification. However, reported methods are mainly limited to nucleophilic modification of ring-opening species. Herein, we report a distinct electrophilic modification method, smoothly converting pyridines into arene-1,3-dialdehydes or naphthalene-1,3-dialdehydes.

Skeletal editing of 4-arylpyrimidines into diverse nitrogen heteroaromatics via four-atom synthons.

Scaffold hopping is a key strategy in drug discovery. While one-to-one scaffold hopping strategies are thriving and evolving, one-to-multiple strategies remain challenging to design. We present here a distinct scaffold hopping strategy for the skeletal editing of pyrimidines into a wide range of heteroarenes through the addition of nucleophiles, ring-opening, fragmentation, and ring-closing (ANROFRC) processes.

Ratiometric absorbance and fluorescence dual model immunoassay to detect ochratoxin a based on ZIF-8@uranine and p-nitrophenol.

Ochratoxin A (OTA) as a mycotoxin has strong carcinogenicity and can affect human health. Thus, it is necessary to establish an accurate method to detect OTA. Herein, a ratiometric absorbance and fluorescence dual model immunoassay based on ZIF-8@uranine (ZIF-8@UR) and p-nitrophenol (PNP) was developed.

Advances and Mechanistic Studies of Cu-Based Heterostructures for Nitrate Reduction.

Ammonia is a carrier of high-energy density and a key component of agricultural fertilizers. Conventionally, the large-scale Haber-Bosch synthesis of ammonia necessitates harsh temperatures and pressures in excess of >500 °C and >200 atm, respectively, leading to considerable greenhouse gas emissions. Simultaneously, the intense use of nitrogen fertilizers and their discharge as agricultural waste have resulted in widespread nitrate accumulation in aquatic environments, posing serious risks to human health and ecological balance.

One-Step Microwave Solid-State Synthesis of N, S Co-Doped Carbon Dots and Their Multifunctional Applications.

Nitrogen and sulfur co-doped yellow-green fluorescent carbon dots (N,SCDs) were synthesized using thiourea and 5-sulfo salicylic acid as raw materials through a one-step microwave solid-phase method. A series of characterizations, including transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared (FT-IR), UV-Vis spectrum, and fluorescent spectrum, were conducted, revealing that N,SCDs are carbon dots with an average size of approximately 5.65 nm.

Construction of a sandwich-type DNA biosensor based on functionalized MOF@COF nanomaterials for the detection of NSCLC biomarker ctDNA.

As a key diagnostic biomarker for non-small cell lung cancer (NSCLC), the sensitive detection of circulating tumor DNA (ctDNA) is crucial for early-stage disease detection and monitoring. However, the existing detection methods still have limitations in terms of sensitivity, cost and operational simplicity. In this study, we successfully constructed a novel sandwich-structured electrochemical biosensor based on a methylene blue (MB)-based signal indication system, leveraging the synergistic effects of metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), to realize the efficient quantitative analysis of ctDNA.

GSAformer: Group sparse attention transformer for functional brain network analysis.

Functional brain network (FBN) analysis based on fMRI has proven effective for neurological/mental disorder classification. Traditional methods usually separate the FBN construction from the subsequent classification tasks, resulting in a suboptimal solution. Recently, transformers, known for their attention mechanisms, have shown strong performance in various tasks, including brain disorder classification.

Glymphatic dysfunction assessed by DTI-ALPS index predicts early cognitive impairment in acute subcortical infarcts: a prospective clinical cohort study.

Background: The glymphatic system (GS), responsible for clearing neurotoxic proteins (such as β-amyloid and tau protein), is critical in stroke pathophysiology. However, its role in acute post-stroke cognitive impairment (PSCI) remains unclear. We investigated GS dysfunction via the DTI-ALPS index in acute subcortical infarct patients and its association with early cognitive decline.

Lattice plainification flattens the crystal structure of nickel-rich layered cathodes.

The extremely fast charging/discharging of nickel-rich LiNiCoMnO (NCM) cathodes has raised concerns about rapid capacity decay. The birth defects and fragile lattice result in the sluggish Li diffusion kinetics and unfavorable structural degradation. Moreover, lattice strain, mechanical failures, surface reconstruction, and interfacial side reactions accelerate the decay process.

Pore connectivity evaluation and seepage characteristic of ultra deep carbonate reservoirs of permian Qixia formation in NW Sichuan basin.

Ultra-deep carbonate reservoirs in the Permian Qixia Formation of the Sichuan Basin, particularly those exceeding 7000 m in depth, have emerged as a significant focus for exploration and development. However, production capacities between adjacent wells can vary by up to two orders of magnitude due to the multi-scale heterogeneity of pore connectivity, which poses challenges for accurately predicting well performance. This study utilizes thin-section analysis, high-pressure mercury injection (HPMI), scanning electron microscopy (SEM), and other techniques to investigate pore connectivity in ultra-deep reservoirs.

Os-Single-Atom Anchored Artificial Enzymes with POD-Mimetic Activities as Smartphone-Based Biosensor for the Visual and Multimodal Detection of Food Additives.

Real-time and high-efficient detection of food additives is of great significance for global public health. As a popular biosensor, colorimetric detection has been widely applied in various fields, including the food industry. However, owing to the complex structure, weak ROS-catalytic activities and unclear catalytic mechanism, recently reported biocatalysts as biosensors still face major challenges in achieving high-efficient and multimodal aspects.

Synergistic integration of oxygen vacancy enrichment and Z-scheme heterojunction in novel BiO/TiO photocatalyst for enhanced tetracycline degradation in wastewater.

The novel Z-scheme heterojunction BiO/TiO photocatalytic system with oxygen-rich vacancies was constructed in this paper, which realized the efficient degradation of tetracycline. The tetracycline was 92.2 % removed by BiO/TiO after 60 min of visible-light driving, which is not only attributed to the high density of oxygen vacancies (0.

Genomic and transcriptomic insights into the molecular responses of a biocrust-derived oleaginous microalga sp. WL1 to nitrogen depletion and recovery.

Microalgae surviving in extreme conditions evolve tolerance mechanisms to diverse environmental stresses. Environmental nitrogen limitation or nitrogen starvation poses a significant threat to the growth of microalgae, but it is an effective factor in inducing lipid accumulation in many microalgal species. In this study, we report the genome sequence of a promising oil-producing strain, sp.

Fostering academic engagement through soft skills and positive emotions: a sustainable development perspective on university education.

Introduction: Soft skills, including curiosity, initiative, perseverance, social awareness, adaptability, and leadership, are increasingly recognized as essential for fostering positive emotions and academic engagement in higher education. However, the pathways linking these skills to academic engagement remain underexplored, especially within the Chinese university context.

Methods: This study investigated the relationships among soft skills, positive emotions, and academic engagement among 335 undergraduate students (197 females, 58.

Research progress on peptides that inhibit melanin synthesis.

Melanin produced by melanocytes, primarily determines human skin color and protects against ultraviolet radiation. However, excessive melanin deposition can lead to skin conditions such as freckles, age spots, and moles, potentially causing aesthetic concerns and psychological distress. Consequently, there is significant research interest in developing safe and effective whitening products that inhibit melanin synthesis.

Nanozyme and dye-driven paper-based sensor array: A novel convenient solution for crude baijiu quality discrimination.

The quality of crude baijiu significantly influences the flavor and overall quality of the final product. Herein, we developed a novel three-channel colorimetric sensor array integrating methylene blue, Rhodamine B, and methyl orange with reactive radicals (SO₄•) generated via a CoCu@g-C₃N₄/PMS system. The sensor accurately discriminated eight reducing substances through PCA, LDA, and HCA.

Co(III)-Catalyzed Dual Carbon-Coupling of Tertiary Allylic Alcohols via Carbon-Skeleton Rearrangement.

A Co(III)-catalyzed dual C-C coupling of sterically hindered tertiary allylic alcohols (TAA) with aldehydes via carbon-skeleton rearrangement has been developed. This transformation features a cascade 1,3-aryl transposition and highly regioselective cross-coupling at the C2- and C3- positions of TAA. The combination of experimental and computational studies revealed the synergetic mechanism of Co(III)-catalysts and B(CF) to enable β-aryl elimination and direct selective trapping of reactive intermediates.

Abnormal spontaneous brain activity of white matter in patients with cerebral small vessel disease.

Cerebral small vessel disease (CSVD) is a nervous system disease caused by small vessel lesions in the brain. The abnormal changes in white matter (WM) function in patients with CSVD remained unclear. Therefore, the purpose of this research was to study the abnormal function of WM in patients with CSVD by measuring the amplitude of low-frequency fluctuations (ALFF).

Highly efficient peroxymonosulfate catalyst prepared from electrolytic manganese residues coupled with Camellia oleifera shell biochar for ethylparaben degradation.

Pharmaceuticals and personal care products (PPCPs) contamination can be effectively remediated using sulfate radical-based advanced oxidation processes (SR-AOPs). In this work, a novel composite catalyst (EMR-BC) was successfully prepared using Camellia oleifera shell (COS) biochar (BC) coupled with electrolytic manganese residue (EMR), and the as-obtained catalyst was used to activate peroxymonosulfate (PMS) for the degradation of ethylparaben (EtP). EMR-BC showed superior catalytic performance comparing to EMR and BC, with an EtP remove rate of 97.

Degree centrality alterations in different frequency bands in chronic insomnia: A resting-state fMRI study.

Purpose: Abnormal spontaneous neural activity in chronic insomnia (CI) has been identified in previous neuroimaging studies. However, whether the spontaneous neural activity is frequency-specific in CI is largely unknown.

Methods: We used resting-state functional magnetic resonance imaging (rs-fMRI) and degree centrality (DC) analysis to examine spontaneous neural activity in 37 CI patients and 20 healthy controls (HCs) across four frequency bands: slow-5 (0.

Embedding Fe/FeO Heterojunctions in Nitrogen-Doped Carbon Nanotubes for Efficient Removal of Organic Pollutants via Heterogeneous Electro-Fenton Catalysis.

The electro-Fenton process is considered one of the most reliable techniques for eliminating organic pollutants from water. However, its performance is still not up to par with its potential due to the lack of cathodic catalysts with the essential cycling catalytic functionality required for sustained Fenton reactions. Herein, Fe and FeO heterojunctions embedded in N-doped carbon nanotubes stitched on porous nitrogen-doped carbon (denoted Fe/FeO@PNC) are fabricated and employed as a bifunctional cathode catalyst for the highly efficient degradation of organic pollutants.

Machine learning discrimination of quality grades of base liquor integrating GC-TOF/MS and GC-IMS data analysis: Case study of strong-flavor Chinese baijiu.

The flavor of base liquor is critical to the grading quality of Baijiu. This study focuses on the base liquor grades of five different strong-flavor Baijiu brands. Headspace Solid-phase Microextraction Gas Chromatography Time-of-flight Mass spectrometry (HS-SPME-GC-TOF/MS) and Headspace Gas Chromatography Ion Mobility Spectrometry (HS-GC-IMS) identified 313 and 188 compounds respectively.

Construction of an effective colorimetric and fluorescent dual-mode microneedle patch for non-destructive detection of nitrite in pickling foods.

Substantial health risks are associated with nitrite in foods, coupled with limitations of existing detection methods (e.g., complex pretreatment, lack of portability), necessitate innovative solutions.