Unmasking Phytotoxicity and Interaction Mechanism of Two Phthalate Esters in Lettuce: Evidences from Biotransformation Processes, Metabolic Response and Molecular Network Perturbations.

Vegetables are considerably affected by plasticizer pollution. This study investigated the transformation process and toxic mechanisms of dimethyl phthalate (DMP) and butyl benzyl phthalate (BBP), in lettuce. Six phase I transformation products of DMP and nine phase I transformation products of BBP were screened and identified using UPLC-QTOF-MS, which were primarily generated via hydrolysis, hydroxylation, and decarboxylation.

Predicting art university students' entrepreneurial intention: A hybrid SEM-ANN approach.

In recent years, academics and policymakers have increasingly focused on entrepreneurial behavior among university students. While existing studies have explored the entrepreneurial intention (EI) of students from various academic disciplines, few have specifically examined the EI of art university students. Based on the Diffusion of Innovations Theory (DOI) and the Theory of Planned Behavior (TPB), this study explores the factors influencing art university students' EI and assesses each factor's relative importance.

An novel cloud task scheduling framework using hierarchical deep reinforcement learning for cloud computing.

With the increasing popularity of cloud computing services, their large and dynamic load characteristics have rendered task scheduling an NP-complete problem.To address the problem of large-scale task scheduling in a cloud computing environment, this paper proposes a novel cloud task scheduling framework using hierarchical deep reinforcement learning (DRL) to address the challenges of large-scale task scheduling in cloud computing. The framework defines a set of virtual machines (VMs) as a VM cluster and employs hierarchical scheduling to allocate tasks first to the cluster and then to individual VMs.

Upcycling shrimp processing by-products into dual-functional peptides: Insights into bioactivity and flavor.

Shrimp processing produces a significant quantity of by-products. They are abundant in proteins, which can serve as excellent precursors of bioactive and taste-active peptides. This review systematically summarizes recent progress in bioactive and taste-active peptides from shrimp by-products, compares main preparation methods including enzymatic hydrolysis and microbial fermentation, reviews bioactive and taste-active activities, and discusses the underlying mechanisms and structure-activity relationships.

Enhanced peroxymonosulfate activation through visible-light-responsive ultrathin phosphorus-iron-codoped g-CN nanosheets for efficient naproxen degradation.

An efficient photocatalyst was constructed via a simple single-stage thermal condensation reaction and applied to photoinduced peroxymonosulfate (PMS) activation for naproxen (NPX) degradation. Batch experiments demonstrated that phosphorus (P)-iron (Fe)-codoped g-CN (PFeCN) exhibited superior catalytic performance compared to previously reported catalysts, achieving 97 % NPX degradation within 20 min and a reaction rate constant approximately tenfold higher than that of pristine g-CN. PFe codoping increased active site exposure, improved charge carrier separation efficiency, and enhanced light absorption capacity.

Sliding window constrained fault-tolerant filtering of compressor vibration data.

This paper presents a sliding window constrained fault-tolerant filtering method for sampling data in petrochemical instrumentation. The method requires the design of an appropriate sliding window width based on the time series, as well as the expansion of both ends of the series. By utilizing a sliding window constraint function, the method produces a smoothed estimate for the current moment within the window.

Cyanuric acid in Paramecium secretions is an efficient quorum sensing inducer.

Quorum sensing is a process of bacterial chemical communication via extracellular signal molecules known as autoinducers, allowing synchronized collective behavior changes related to population density. However, the ecological significance of quorum sensing in multi-species communities, particularly coexisting with predators, remains unaddressed. In this study, we discovered that cyanuric acid (CA), a compound secreted by the widespread protozoan Paramecium, significantly influences the LuxR-type quorum sensing in Pseudomonas aeruginosa PAO1.

Flow in choral singing: associations with perceived choral memory performance and well-being among older adults.

Drawing on flow theory, this study examines relationships between choral environment, song style, and flow, proposing a choral experience model to investigate associations with perceived choral memory performance and well-being among older choir members. We employed structural equation modeling (SEM) to analyze data from 412 older adult participants in amateur choral groups across China. Results reveal significant positive associations between five factors (skill-challenge balance, clear goals, immediate feedback, song style, and choral environment) and flow.

Drought-induced transposon expression reveals complex drought response mechanisms in .

Transposable elements (TEs) are abundant components of plant genomes, yet their transcriptional activity and potential biological roles remain underexplored, especially under environmental stress conditions. This study investigates the transcriptional dynamics of TEs in during drought stress in seed development, aiming to uncover their contributions to stress responses and seed germination. RNA-seq data were analyzed for TE transcriptional activity in wild-type (WT) and CRISPR-edited mutant lines of .

Orthogonal signal-transducing electrochemical dual-aptasensor for ultrasensitive parallel detection of GP73 and AFP in serum.

Background: Golgi protein 73 (GP73) has emerged as a promising serological biomarker for hepatocellular carcinoma (HCC), with its combination with alpha-fetoprotein (AFP) substantially improving diagnostic precision in early-stage HCC detection. To address this clinical need, we constructed an electrochemical dual-aptasensor for parallel quantification of GP73&AFP.

Results: GP73 aptamer (GP73) functionalized with reduced graphene oxide-ferrocene-polyaniline (rGO-Fc-PANi) nanocomposites and AFP aptamer (AFP) conjugated with nitrogen-doped reduced graphene oxide-cuprous oxide (NrGO-CuO) nanostructures were employed as the dual-signal probes.

New rhodium(III)-triphenylphosphine complexes with 5-halogenate-8-hydroxyquinoline as ligands: synthesis, characterization, cytotoxicity, and mechanism of action.

The incorporation of triphenylphosphine (PPh) can enhance the antiproliferative activity of complexes. Herein, four Rh(III) complexes GUPT1-GUPT4 were synthesized. GUPT4 exhibited stronger anticancer activity than HGU, cisplatin, and GUPT1-GUPT3 against human non-small cell lung A549 and its cisplatin-resistant A549 cell line (CR-A549), with IC values of 6.

Enhanced Oilfield-Produced-Water Treatment Using Fe-Augmented Composite Bioreactor: Performance and Microbial Community Dynamics.

The presence of recalcitrant organic compounds in oilfield-produced-water poses significant challenges for conventional biological treatment technologies. In this study, an Fe-augmented composite bioreactor was developed to enhance the multi-pollutant removal performance and to elucidate the associated microbial community dynamics. The Fe-augmented system achieved efficient removal of oil (99.

Predicting geriatric environmental safety perception assessment using LightGBM and SHAP framework.

Global population aging highlights the need to understand how the elderly perceive safety in urban public spaces. This study used image semantic segmentation to identify key visual elements from panoramic images. A dataset was created by combining manual scoring with deep learning to explore how pocket park environments impact older adults' safety perceptions.

Microbial responses to changing plant community protect peatland carbon stores during Holocene drying.

Peatlands are among the most effective long-term carbon sinks. However, climate change is triggering major ecological shifts with widespread woody plant expansion in peatlands. How microbial processes regulate carbon storage under these vegetation transitions remains uncertain.

Seasonal bioaccumulation and biomagnification of typical organochlorine pesticides in the Pearl River Estuary, South China.

As a typical organochlorine pesticide, dichlorodiphenyltrichloroethane (DDT) and its metabolites (dichlorodiphenyldichloroethane (DDD), dichlorodiphenylmethane (DDM), dichlorodiphenyldichloroethylene (DDE), and bis(p-chlorophenyl)-chloroethylene (DDMU)) (collectively referred to as DDXs), have been widely detected in the Pearl River Estuary (PRE). However, seasonal variations in land runoff and the transformation of DDXs complicate their bioaccumulation characteristics in the PRE. The present study analyzed the sediment and aquatic organisms from both dry and wet seasons to investigate the seasonal characteristics of bioaccumulation of DDXs in the PRE.

Effects of hibernation on the bioaccumulation and tissue distribution of per- and polyfluoroalkyl substances in frogs (Rana tigrina cantor) via skin exposure.

We investigated the bioaccumulation, tissue distribution, maternal transfer and effects of hibernation of per- and polyfluoroalkyl substances (PFASs) in frogs via skin exposure. Relationships between toxicokinetic parameters, such as assimilation efficiencies and depuration rate constants of PFASs, and carbon chain length were revealed, indicating a high bioaccumulation potential for PFASs with longer carbon chains. Eggs were the main site for the deposition of perfluoroalkyl sulfonic acids (PFSAs) and C9 - C16 perfluoroalkyl carboxylic acids (PFCAs), whereas the carcass was the primary organ for C4 - C8 PFCAs.

Effect of rare earth cerium doping on the activity of ZnO nanomaterials for producing HO by piezoelectric catalysis.

Piezoelectric catalysis is an eco-friendly method to obtain hydrogen peroxide (HO), whereas, the challenges for HO synthesis, by piezoelectric catalysis, is the unsatisfied yield and adsorption reactant. Herein, for promoting the yield of HO in piezocatalytic, a series of rare earth cerium are doped into zinc oxide. The Ce-ZnO(CZ) expose more active sites and owning stronger piezo-response.

Multicomponent Tandem Reactions for the Synthesis of -Dibromo Compounds via an ATRA/Elimination/Nucleophilic Substitution Process.

We developed a metal-free tandem atom transfer radical addition/elimination/nucleophilic substitution of alkenes with CBr and amines to synthesize a series of α-amino-substituted -dibromo compounds which are useful building blocks in diverse organic synthesis. Moreover, this transformation avoids the usage of any catalysts and external additives and also exhibits a broad substrate scope and high functional group compatibility, as demonstrated by the late-stage modification of a pharmaceutically relevant molecule (ibuprofen). Notably, secondary amines play a dual role as bases and nucleophiles in this reaction.

Research Progress on Organic Fluorescent Probes Based on Pesticide Detection.

The widespread use of pesticides has led to their residues posing a serious threat to the environment and the health of plants and animals, making the development of efficient and convenient detection technologies an urgent priority. Organic fluorescent probes have become a research hotspot owing to their rapid response, visual detection capabilities, and potential for portability. Therefore, this paper reviews the research progress of organic fluorescence detection of pesticides based on the mechanisms of enzymatic reactions, competitive complexation with metal ions, nucleophilic/electrophilic reactions and hydrogen bonding in the past three years (From 2023 to 2025).

Promoting selective dephosphorylation and aromatic nitroreduction by in-situ anchoring gold/silver bimetallic nanoparticles on ceria/polyethyleneimine nanosheets.

Addressing the dual challenges of phosphorus resource scarcity and organic pollutant treatment, this study develops a bifunctional ceria/polyethyleneimine/AuAg (CeO/PEI/AuAg) catalyst through self-assembly and in-situ reduction anchoring strategies for both efficient dephosphorylation and aromatic nitroreduction. Its components optimize the catalytic process through multilevel synergy: i) the oxygen vacancies in the CeO component interact with HO to generate lots of protonated hydroxyl groups, which not only enhance the adsorption for phosphates but also facilitate continuous electron enrichment through the Ce/Ce redox cycle, ii) the PEI component enhances the interfacial enrichment of phosphates, BH, and p-nitrophenol through amino group protonation and serves as a green reductant to drive the in-situ uniform anchoring of AuAg bimetallic nanoparticles onto the CeO support, iii) the AuAg bimetallic component directs the electrons enriched in CeO oxygen vacancies and the reducing electrons provided by BH to dual reaction sites via strong metal-support interactions and hierarchical electron transfer channels, thereby improving reaction kinetics. Experimental results show that this catalyst achieves a 3.

Development of a justification process for selecting alternative risk reduction measures.

Introduction: The aim of this study is to develop a process for determining a set of alternative preventive measures to reduce risk levels, using the example of reducing the incidence of occupational pneumoconiosis in miners under conditions of financial cost minimization.

Methods: This study was conducted using a system analysis to identify priority directions for risk reduction under limited financial resources based on the relationship between the measures and their risk reduction efficiency. A methodology was developed to justify the selection of risk reduction measures from a set of alternatives based on the calculation of an efficiency factor grounded in financial losses.

Influence of occupational safety culture on the occupational risk level in the organization.

Introduction: This study aims to develop a methodology for assessing the risk of hazardous situations, incidents, and related events, with consideration of the level of "occupational safety culture" among employees within an organization.

Methods: The research employs a systematic approach, incorporating mathematical and simulation modeling to evaluate the influence of safety culture on occupational risk levels.

Results: A methodology has been developed to assess the safety culture level and its impact on the likelihood of hazardous events.

Metal ion-induced structural reconstruction in a porphyrin MOF for ultrasensitive detection of Cr and Al.

Porphyrin-based metal-organic frameworks (MOFs) are a class of porous materials constructed from metal nodes and porphyrin organic ligands. Due to their unique structural and functional properties, they have demonstrated broad application potential in catalysis, sensing, separation, adsorption, biochemistry, and electrochemical processes. In this study, we developed a highly selective and sensitive porphyrin-based metal-organic framework (Eu@Tb-TCPP) for the "turn-on" fluorescence detection of Cr and Al ions.

A label-free electrochemical aptasensor utilizing NRGO-Fc-Pt@Pd NPs for ultrasensitive detection of Golgi protein 73 in human serum.

Golgi protein 73 (GP73) is highly expressed in hepatocellular carcinoma (HCC) and considered a sensitive serum biomarker for HCC diagnosis. Herein, a label-free electrochemical aptasensor for ultrasensitive detection GP73 based on nitrogen-doped reduced graphene oxide-ferrocene-platinum@palladium nanoparticles (NRGO-Fc-Pt@Pd NPs) was constructed. The NRGO-Fc-Pt@Pd NPs offered excellent conductivity, biocompatibility, and large surface area, serving as both an electrode modifier and a redox probe due to Fc's good electroactivity.

Particle associated denitrification in coastal aquaculture water.

The nitrate reductase S (nirS) type denitrifying bacteria is important for nitrate removal, and suspended particulate matter (SPM) in coastal aquaculture water provides a microenvironment for denitrification to occur. However, it is currently unclear about the denitrification mechanism for nitrate removal occurred on SPM in coastal aquaculture water. SPM with different particle sizes (0.