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The widespread use of pesticides has led to their residues posing a serious threat to the environment and the health of plants and animals, making the development of efficient and convenient detection technologies an urgent priority. Organic fluorescent probes have become a research hotspot owing to their rapid response, visual detection capabilities, and potential for portability. Therefore, this paper reviews the research progress of organic fluorescence detection of pesticides based on the mechanisms of enzymatic reactions, competitive complexation with metal ions, nucleophilic/electrophilic reactions and hydrogen bonding in the past three years (From 2023 to 2025). The aim is to provide theoretical support for future research that needs to focus on the design of synergistic probes with multiple mechanisms, the development of new sensing systems with intelligent responses, and the optimization of detection strategies combined with artificial intelligence algorithms, in order to promote the development of detection technology in the direction of high precision and intelligence, and to provide theoretical support for the construction of pesticide rapid detection platforms applicable to multiple scenarios.
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http://dx.doi.org/10.1007/s10895-025-04440-6 | DOI Listing |
Eur J Pharmacol
September 2025
Faculty of Medicine, Department of Histology and Embryology, İzmir Katip Çelebi University, İzmir, Turkiye.
Age is the most significant risk factor for Parkinson's disease, a common and progressive neurodegenerative disorder; however, exposure to toxic substances is also strongly implicated. Rotenone, an organic pesticide, induces neuropathological features of Parkinson's disease, and is widely used to create rodent models of the condition. Although the molecular mechanisms involved in the onset and progression of the disease are still unknown, neurodegenerative diseases due to protein accumulation in certain areas of the brain, have been associated with endoplasmic reticulum stress.
View Article and Find Full Text PDFToxicol Lett
September 2025
Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.100, Haining Road, Shanghai 200080, China. Electronic address:
Bisphenol A (BPA), a synthetic organic compound widely used in plastic products, toys, water pipes, and flame retardants, has been linked to the onset and progression of various cancers. This study explores the association between BPA and bladder cancer using bioinformatics approaches. We applied the ssGSEA algorithm to calculate BPA-related scores in TCGA-BLCA cohort and classify patients based on this.
View Article and Find Full Text PDFWater Res
September 2025
Advanced Institute of Natural Sciences, Beijing Normal University, Zhuhai 519087, China. Electronic address:
Plantation forest areas are rapidly expanding worldwide. Forests at different stand ages exhibit distinct patterns in litterfall input, soil microbial diversity, and enzyme activity, all of which potentially affect the properties of dissolved organic matter (DOM). DOM is an important precursor of disinfection byproducts (DBPs).
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, 212013, PR China. Electronic address:
Aptamers are single-stranded DNA or RNA oligonucleotides that can bind to specific target molecules with high affinity and specificity. Fluorescence DNA aptamer-based biosensors (aptasensors) have emerged as powerful analytical tools for detecting diverse targets, ranging from food contaminants to disease biomarkers, owing to their exceptional specificity, high sensitivity, and cost-effectiveness. This review systematically summarizes recent advances in the design strategies of fluorescence aptasensors, focusing on three key approaches: (1) fluorescence resonance energy transfer-based signal amplification, (2) nanomaterial-enhanced probes, and (3) multi-channel platforms for simultaneous detection.
View Article and Find Full Text PDFBone
September 2025
Department of Mechanical Engineering, Texas A&M University, 3123 TAMU, College Station, TX, 77843, United States of America; School of Engineering Medicine, Texas A&M University, 1020 Holcombe Blvd, Houston, TX 77030, United States of America. Electronic address:
Breast, prostate and lung cancer cells frequently metastasize to bone, leading to disruption of the bone microstructure. This study utilized mechanical testing with micro-CT imaging, digital volume correlation (DVC), and atomic force microscopy (AFM) nanomechanical testing to examine the mechanical property variations in mouse long bones (tibia) with metastatic lung cancer cell involvement, spanning from the whole-bone scale to the microstructural level. In addition, we also investigated how metastatic invasion alters the morphology of hydroxyapatite nanocrystals in bone at the nanometer scale.
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