Modeling the impact of social determinants on breast cancer screening: a data-driven approach.

Background: This study addresses the critical science challenge of operationalizing social determinants of health (SDoH) in clinical practice. We develop and validate models demonstrating how SDoH predicts mammogram screening behavior within a rural population. Our work provides healthcare systems with an evidence-based framework for translating SDoH data into effective interventions.

Digital mental health interventions for adolescents and young people (10-24 years) in Africa: A protocol for a systematic review of mental health outcomes, engagement, and equity considerations.

Background: Adolescents and young people (AYP) aged 10-24 years in Africa experience a high burden of mental health disorders but face significant barriers to accessing care, including a severe shortage of mental health professionals, stigma, and limited integration of mental health services into primary healthcare. Digital mental health interventions (DMHIs) offer a promising avenue to bridge these gaps by providing accessible, scalable, and potentially equitable support. However, little is known about the effectiveness, acceptability, and equity impacts of these interventions among African AYP.

The genome sequence of the zebra danio, (Hamilton, 1822) (Cypriniformes: Danionidae).

We present a genome assembly from a specimen of (zebra danio; Chordata; Actinopteri; Cypriniformes; Danionidae). The genome sequence has a total length of 1 413.66 megabases.

The genome sequence of the China Limpet, Gmelin, 1791 (Patellidae).

We present a genome assembly from a specimen of (China Limpet; Mollusca; Gastropoda; Patellidae). The genome sequence has a total length of 693.56 megabases.

(Un)timely care: findings from the Waiting Times project.

There is a historic crisis in waiting times in the UK's National Health Service. Crisis brings both a call for judgement - a response to the question 'what has gone wrong?' - and a call to action, such as better management, more resources, strategies to mitigate staff burnout, or even a shift in access commitments to reduce demand. However, not all forms of waiting are a sign of service inefficiency or failure, or a form of abandonment or lack of care.

The genome sequence of a cranefly, ( ) Loew, 1873.

We present a genome assembly from an individual female cranefly, (Arthropoda; Insecta; Diptera; Tipulidae). The genome sequence has a total length of 1,204.70 megabases.

Persistent progression independent of relapse activity in multiple sclerosis.

Patients with relapsing-remitting multiple sclerosis (RRMS) may experience disability progression independent of relapse activity (PIRA), which can be an early sign of secondary progressive MS (SPMS). We defined persistent PIRA as ongoing sustained disability over the entire available follow-up period. However, PIRA events can regress over time.

Exploring the Lived Experiences of Transgender Women With Previous Sexual Offense Convictions in the Community in the UK.

Transgender individuals with previous convictions for sexual offenses are an under-researched yet growing population in the UK. This study adopted a qualitative approach to exploring the lived experiences of three such individuals who were currently living in the community under the management of Probation Services. Interpretative Phenomenological Analysis was used to analyze the data derived from semi-structured interviews with the participants.

A qualitative analysis of a nationally representative survey of the state of chronic non-cancer pain management in Australia.

Background And Objectives: Although general practitioners (GPs) are the first-line treatment providers for chronic non-cancer pain (CNCP) in Australia, the experience of patients in this context is not well documented. This study explored patients' experiences with GPs managing their CNCP.

Method: Qualitative responses to two open-ended questions about GP care from adult respondents (n=200) to Chronic Pain Australia's 2021 National Pain Survey were thematically analysed.

Recommendations for studying the association of the cancer diagnosis to treatment interval with overall survival: a modified Delphi process.

Background: The duration from diagnosis to primary treatment initiation (DTI) is an important interval for patients with cancer, as delayed treatment has been found to be associated with heightened recurrence rates and worsened survival. Studying the association between DTI duration and overall survival (OS) is biased and confounded by clinical triaging, heterogeneous definitions, and variation in analytic approaches.

Objective: To develop consensus-based guidance for conducting studies investigating the association of DTI duration and OS.

Towards a trait-based framework for protist ecology and evolution.

Protists comprise the vast majority of eukaryotic genetic and functional diversity. While they have traditionally been difficult to study due to their small size and varied phenotypes, environmental sequencing studies have revealed the stunning diversity and abundance of protists in all ecosystems. Protists are key primary and secondary producers across many biomes, with ecological specializations that range from mutualism to parasitism, complex predation behaviors, mixotrophy, detritivory, and saprotrophy.

4Ps framework: practical actions to protect individual health in the current climate crisis.

Climate change driven by anthropogenic greenhouse gas (GHG) emissions represents an immediate and grave threat to human health and survival. Sea level rise, altered weather patterns and increasingly frequent and severe extreme weather events can damage health directly (eg, injury, heat stress, altered aeroallergen and particulate exposure). They also bring indirect health impacts through altered patterns of zoonotic and vectorborne diseases, disruption of food systems and downstream social consequences (economic collapse, mass migration and conflict).

Prospective assessment of prognostic significance of malignant peritoneal cytology in endometrial cancer: An NRG Oncology / Gynecologic Oncology Group study on GOG-210 protocol.

Objective: To examine the association between malignant peritoneal cytology and survival outcomes in endometrial cancer.

Methods: This was an ancillary analysis of prospectively collected surgical-pathological data in the NRG Oncology / Gynecologic Oncology Group study on GOG-210 protocol. The study population included 2383 patients with stage I-III endometrial cancer from 2003 to 2011.

Deep Learning Modeling to Differentiate Multiple Sclerosis From MOG Antibody-Associated Disease.

Background And Objectives: Multiple sclerosis (MS) is common in adults while myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is rare. Our previous machine-learning algorithm, using clinical variables, ≤6 brain lesions, and no Dawson fingers, achieved 79% accuracy, 78% sensitivity, and 80% specificity in distinguishing MOGAD from MS but lacked validation. The aim of this study was to (1) evaluate the clinical/MRI algorithm for distinguishing MS from MOGAD, (2) develop a deep learning (DL) model, (3) assess the benefit of combining both, and (4) identify key differentiators using probability attention maps (PAMs).

Temporal Trends in Sexual Identity and Sociodemographic Disparities in Stockholm, Sweden, 2010-2021.

To examine temporal trends in sexual identity and sociodemographic disparities in Sweden after gender-neutral marriage legislation in 2009. We analyzed 3 cross-sectional surveys from the Stockholm Public Health Cohort (2010, 2014, 2021) that included 76 083 participants 16 years or older. Weighted Poisson regression was used to estimate associations between sexual identity and sociodemographic covariates.

The "most beautiful place" where "it's not possible to live": A qualitative study of relational well-being in an area of climate vulnerability, Bangladesh.

Purpose: Climate change is the greatest global health threat of the 21st century, but little is known about well-being in climate vulnerable populations. We investigate how well-being is shaped by common and unique stressors in an area of climate vulnerability in Bangladesh.

Methods: We present findings from 60 semi-structured in-depth interviews.

The association between adolescents' independent food purchasing and dietary quality differs by socioeconomic status: Findings from a pilot study.

During adolescence, many young people start to make more independent food purchases. Subsequently, these independent food choices will increasingly contribute to their overall diet quality; little is known, however, about this relationship. This pilot study aimed to examine the role adolescents' independent food purchases play in their diet quality and assess if these relationships vary according to socio-economic status.

The role of emotional intelligence in shaping pre-service teachers' cultural beliefs.

Cultural beliefs and emotions have become recognised aspects of the teaching profession. This study examined the association between emotional intelligence (EI) and cultural beliefs using self-reported survey data collected from pre-service teachers at the beginning of their studies (N = 777). These pre-service teachers entered teacher education in 2021 and were studying in five different Finnish universities that geographically represent four regions in Finland.

Patient-Centered Measures of Goal Concordance in Geriatrics and Palliative Care: A Scoping Review.

Importance: Goal concordance underpins high-quality care for patients with serious illness and older adults with multimorbidity and geriatric syndromes; however, a criterion standard for measurement is lacking.

Objective: To identify and describe patient- and caregiver-reported measures of goal concordance for patients with serious illness, geriatric syndromes, and multimorbidity to create a conceptual model of goal-concordance measurement.

Evidence Review: This scoping review included an electronic search across MEDLINE, Embase, Web of Science Core Collection, the CINAHL, and PsycINFO through September 2024.

Radiotherapy for Growing Vestibular Schwannomas.

Importance: In the literature, there is a lack of data reporting tumor control rates after radiotherapy in actively growing vestibular schwannomas (VS). Data for this rarely studied population are needed.

Objective: To estimate tumor control rates in radiologically growing VS treated with first-line radiotherapy.