Customization of existing TPMS lattices to enhance biocompatibility and active cell proliferation area.

Triply periodic minimal surfaces have garnered significant interest in the field of biomaterial scaffolds due to their unique structural properties, including a high surface-to-volume (S/V) ratio, tunable permeability, and the potential for enhanced biocompatibility. Bone scaffolds necessitate specific features to effectively support tissue regeneration. This study examines the permeability and active cell proliferation area of advanced Triply Periodic Minimal Surface (TPMS) lattice structures, focusing on a novel lattice design.

Preparation, structural characterization, and ultrafast energy transfer dynamics of the phycobilisome-photosystem II megacomplex in a thermophilic cyanobacterium.

Phycobilisome (PBS) is a water-soluble light-harvesting supercomplex found in cyanobacteria, glaucophytes, and rhodophytes. PBS interacts with photosynthetic reaction centers, specifically photosystems II and I (PSII and PSI), embedded in the thylakoid membrane. It is widely accepted that PBS predominantly associates with PSII, which functions as the initial complex in the linear electron transport chain.

Unveiling the Xianbei cavalry: a multidisciplinary approach to restore and analyse the first horse-cavalry armour set in China.

Between the third and sixth centuries AD (Anno Domini), the Xianbei emerged as a dominant nomadic power in the Eastern Eurasian Steppe, distinguished by their exceptional equestrian culture and the pivotal role of cavalry in warfare. Despite their historical significance, detailed knowledge of their cavalry's weaponry and equipment-particularly armour-remains fragmentary. As a critical element of military technology, armour offers valuable insights into ancient combat strategies and cultural practices.

Microgel-Crosslinked, thermo- and mechano- dual Responsive, Ketoprofen-Loaded hydrogels with high mechanical properties and rapid response.

Smart hydrogels have advanced rapidly in recent years. However, systems responsive to a single stimulus are typically triggered by specific cues, limiting their adaptability in complex and dynamic biological environments. To overcome this limitation, this study developed a dual-responsive hydrogel sensitive to both temperature and mechanical stress.

Hybrid nanocomposites of sepiolite with starch and other biopolymers: Enhancing safety in food packaging.

Sepiolite (SP) is a naturally occurring sedimentary silicate clay mineral known for its unique structure, high surface area, and rich surface chemistry, particularly silanol groups (Si-OH), which facilitate strong interfacial interactions in polymer matrices. Its ability to act as a nanofiller has gained attention in the development of advanced biopolymer nanocomposites, especially for food packaging applications where material performance, sustainability, and safety are critical. SP enhances the thermal stability, barrier properties, and mechanical strength of starch and other biopolymer matrices, key factors in extending shelf life.

An adjustable three-layer skull phantom with realistic ultrasound transmission properties.

Transcranial ultrasound research has garnered significant attention due to its non-invasive nature, absence of ionizing radiation, and portability, making it advantageous for both imaging and therapy. A critical aspect of advancing transcranial research lies in understanding the ultrasound transmission performance of the human skull. However, inherent variations in skull shape, physical parameters, and age-related changes pose challenges for comparative studies.

3D bioprinted cell-laden GrooveNeuroTube: a multifunctional platform forneural cell migration and growth studies.

Extensive peripheral nerve injuries often lead to the loss of neurological function due to slow regeneration and limited recovery over large gaps. Current clinical interventions, such as nerve guidance conduits (NGCs), face challenges in creating biomimetic microenvironments that effectively support nerve repair. The developed GrooveNeuroTube is composed of hyaluronic acid methacrylate and gelatin methacrylate hydrogel, incorporating active agents (growth factors and antibacterial agents) encapsulated within an NGC conduit made of 3D-printed PCL grid fibers.

Rapid and sensitive acute leukemia classification and diagnosis platform using deep learning-assisted SERS detection.

Rapid identification and accurate diagnosis are critical for individuals with acute leukemia (AL). Here, we propose a combined deep learning and surface-enhanced Raman scattering (DL-SERS) classification strategy to achieve rapid and sensitive identification of AL with various subtypes and genetic abnormalities. More than 390 of cerebrospinal fluid (CSF) samples are collected as targets, encompassing healthy control, AL patients, and individuals with other diseases.

Evaluation of the effect of autophagy on pseudoexfoliation syndrome.

ObjectivePseudoexfoliation syndrome is a systemic disease of unknown etiology, seen in advanced ages, characterized by extracellular material accumulation in ocular tissues and visceral organs. Autophagy, which is a basic metabolic pathway, provides macromolecule recycling of the cell and maintains cell homeostasis by adapting to the cell's stress environment. The aim of this study was to examine the relationship between specific mechanisms of autophagy and pseudoexfoliation syndrome.

Dual-functional hydrochar via hydrothermal carbonization for norfloxacin removal: Fractal adsorption kinetics and mechanism elucidation.

Escalating concentrations of norfloxacin (NFX) in surface and wastewaters demand sustainable remediation strategies. In this study, dual-functional hydrochars were synthesized from argan nut shells (ArNS) via hydrothermal carbonization (HTC), with process conditions optimized by varying temperature (150-200 °C) and residence time (2-6 h). Among the materials, H1:5@150-4-prepared at 150 °C for 4 h with a biomass-to-water ratio of 1:5-exhibited the best performance, achieving a monolayer NFX adsorption capacity of 27.

Understanding the mechanothermally superior nanotwinned copper: Fabrication procedure, mechanistic models and technological applications.

The rapid evolution of microelectronics requires materials that combine exceptional strength, ductility, and electrical conductivity for joining applications and durable lithium-ion battery anodes. Nanotwinned Cu (nt-Cu) surpasses conventional strengthening approaches, which often compromise ductility and conductivity, by using nanoscale twin boundaries to enhance both mechanical and electrical properties. This review examines the thermomechanical characteristics, fabrication methods, multiscale mechanistic insights, and technological applications of nt-Cu, bridging fundamental science with engineering practice.

In situ rapid gelation and osmotic dehydration-assisted preparation of graphene aerogel and its application in piezoresistive sensors.

This study presents a straightforward and rapid method for preparing graphene aerogel by integrating a sodium alginate (SA)-metal ion crosslinking system, a bubble template, and an osmotic dehydration process. Graphene oxide (GO) nanosheets were dispersed into the solution crosslinked by SA and metal ions, leading to rapid gelation of GO under ambient conditions. To minimize structural damage to the porous network caused by water molecules during the drying process, an osmotic dehydration technique was employed as an auxiliary drying method.

Rational design of Pt-integrated SnNbO/BiMoO monolayer S-scheme heterojunction for efficient ethylene removal toward fresh produce preservation.

Effective removal of ethylene (CH) during fruit and vegetables storage and transport remains a critical challenge for post-harvest preservation. Although S-scheme heterojunctions can improve charge separation and redox capacity for ethylene degradation, their efficiency is still restricted by limited carrier transfer and sluggish oxygen activation. Here, we rationally designed a novel 2D/2D SnNbO/BiMoO monolayer S-scheme heterojunction integrated with Pt co-catalyst to address these limitations.

In-situ extrusion 3D printing with tea polyphenol crosslinking for Hyaluronic acid sodium salt -based composite hydrogel scaffolds.

High-performance hydrogel biomaterials hold considerable promise for advanced wound care. However, the suboptimal mechanical properties of conventional hydrogel materials limit their practical application. In this study, Hyaluronic acid sodium salt (HA), xanthan gum (XG), and N-acryloyl-glycinamide (NAGA) hydrogels with porous structures were successfully fabricated using in-situ extrusion 3D printing technology, and a functionalization strategy involving tea polyphenol (TP) immersion was proposed to enhance material properties through additional hydrogen bonding.

Impact of wettability heterogeneity on methane hydrate growth kinetics in partially water-saturated sediments.

Hypothesis: Gas hydrate formation in sediments is influenced by the availability of gas-water interfacial areas, which governs gas-water interactions. The surface wettability of sediment particles is expected to affect the spatial distribution of water within the pore space, thereby altering the extent of gas-liquid contact. Consequently, by tuning the wettability heterogeneity of the sediment, the spatial distribution of pore water can be regulated, which in turn influences the gas-water interactions and the kinetics of gas hydrate formation.

A collagen/silk fibroin/magnesium hydroxide multifunctional sponge with enhanced mechanical strength, rapid hemostasis, and antibacterial properties for promoting infectious wound healing.

Hemostatic intervention at the bleeding site during early-phase wound management plays a crucial role in reducing trauma-induced complications and mortality, while advanced wound dressings facilitate hemorrhage control, exudate management, and antimicrobial protection to promote optimal healing outcomes. To address these issues, we developed a multifunctional collagen/silk fibroin/Mg(OH)₂ (Col/SF/Mg(OH)₂) composite sponge combining enhanced mechanical strength, rapid hemostasis, and broad-spectrum antibacterial activity. The incorporation of silk fibroin (SF) through covalent crosslinking increased the elastic modulus by 4.

IRF7 drives resistance to oncolytic virotherapy by restricting viral replication and suppressing antitumor immunity.

Oncolytic viruses (OVs) represent a promising approach for cancer immunotherapy by inducing direct tumor lysis and stimulating antitumor immunity. However, tumor-intrinsic resistance remains a major barrier to their efficacy. In this study, we established an OV-resistant MC38 colon cancer model (MC38) and identified interferon regulatory factor 7 (IRF7), a key regulator of type I interferon signaling, as significantly upregulated in resistant cells.

Controlling collagen I orientation on polyetheretherketone implants to improve epithelial sealing.

Transcutaneous devices such as dental implants frequently fail due to infections at their interfaces with epithelial tissues. These infections are facilitated by the lack of integration between the devices and the surrounding soft tissues. This study aims to improve epithelial integration through surface modification of a transcutaneous implant material (polyetheretherketone (PEEK)).

Asymmetric Fe-O-Ni Pair Sites in Two-Step Dealloyed Prussian Blue Analogue Nanocubes Enrich Linear-Adsorbed Intermediates for Efficient Oxygen Evolution.

Ni-Fe (oxy)hydroxides are among the most active oxygen evolution reaction (OER) catalysts in alkaline media. However, achieving precise control over local asymmetric Fe-O-Ni active sites in Ni-Fe oxyhydroxides for key oxygenated intermediates' adsorption steric configuration regulation of the OER is still challenging. Herein, we report a two-step dealloying strategy to fabricate asymmetric Fe-O-Ni pair sites in the shell of NiOOH@FeOOH/NiOOH heterostructures from NiFe Prussian blue analogue (PBA) nanocubes, involving anion exchange and structure reconstruction.

Z-scheme Heterojunction on TS-1 Zeolite Boosting Ultrafast Visible-Light-Driven Degradation of Cr(VI) and Tetracycline.

Photocatalysis has emerged as a promising strategy to address water pollution caused by heavy metals and antibiotics. Zeolites exhibit significant potential in petrochemical catalysis; however, the development of zeolite-based photocatalysts remains a critical challenge for researchers. Herein, a novel Z-scheme heterojunction was designed and fabricated on the titanium-silicon zeolite TS-1 by modifying g-CN via a simple calcination process.

Fabrication of Hydrophilic Gadolinium Hydroxide Sheets via A Gadolinium-Based Precipitation Reaction.

In this work, we report a facile strategy for synthesizing hydrophilic Gd(OH) sheets via a Gd-based interfacial precipitation reaction at the interface of organosilane-modified GdO nanoparticles and a cation exchange resin. This strategy, independent of the specific organosilane used, produces two-dimensional sheets with a distinct lamellar structure and excellent aqueous dispersibility. Characterization confirms the formation of Gd(OH) sheets with promising fluorescent and magnetic properties.

From molecular damage and viscoelasticity to interfacial fracture in soft polymer networks: Insights from mechanochemistry.

Many soft, tough materials have emerged in recent years, paving the way for advances in wearable electronics, soft robotics, and flexible displays. However, understanding the interfacial fracture behavior of these materials remains a significant challenge, owing to the difficulty of quantifying the respective contributions from viscoelasticity and damage to energy dissipation ahead of cracks. This work aims to address this challenge by labeling a series of polymer networks with fluorogenic mechanophores, subjecting them to T-peel tests at various rates and temperatures, and quantifying their force-induced damage using a confocal microscope.

Management of renal cancer with inferior vena cava extension over 30 years: a bi-centric study.

Purpose: In 5-10% of cases, renal cancer extends into the venous system, particularly the inferior vena cava (IVC), which worsens prognosis. This study aims to assess morbidity, mortality, and oncological outcomes of patients treated surgically for renal cancer with IVC extension over a 30-year period, in two experienced centers.

Materials And Methods: This bicentric, retrospective study analyzed patients treated between 1988 and 2020 for renal cancer involving the IVC.

Impact of sociodemographic and socioeconomic factors on functional and health-related quality of life outcomes 24 months after radical prostatectomy.

Introduction And Objectives: High socioeconomic status (SES) is associated with improved oncological outcomes across various cancer types, including prostate cancer. However, limited evidence exists regarding the impact of SES and lifestyle factors on patient-reported outcomes (PROs), including quality of life (QoL), health status (HS), and functional recovery following radical prostatectomy (RP).

Materials And Methods: We conducted a retrospective single-center analysis of 327 patients undergoing RP (177 open, 150 robotic-assisted) assessing pre- and postoperative functional outcomes (QoL, HS, erectile function, continence).

g-CN/BiO hetero-nanosheets as a superior electrocatalyst for nitrate reduction to ammonia.

The faradaic efficiency of the electro-synthesis of ammonia using the nitrate reduction reaction (NORR) relies on an electrocatalyst to hydrogenate NO and simultaneously suppress the hydrogen evolution reaction (HER). Due to the formation of a heterostructure, the faradaic efficiency of g-CN/BiO reaches 91.12% at -0.