In situ rapid gelation and osmotic dehydration-assisted preparation of graphene aerogel and its application in piezoresistive sensors.

This study presents a straightforward and rapid method for preparing graphene aerogel by integrating a sodium alginate (SA)-metal ion crosslinking system, a bubble template, and an osmotic dehydration process. Graphene oxide (GO) nanosheets were dispersed into the solution crosslinked by SA and metal ions, leading to rapid gelation of GO under ambient conditions. To minimize structural damage to the porous network caused by water molecules during the drying process, an osmotic dehydration technique was employed as an auxiliary drying method.

Green synthesis of PVA-LS-MXene composite conductive hydrogel for high-performance skin wound dressings.

Polyvinyl alcohol (PVA)-based hydrogels have been demonstrated to possess excellent biocompatibility and hydrophilicity. Nevertheless, their restricted mechanical resilience and antimicrobial properties have substantially constrained their utility in advanced wound care applications. To address these critical limitations, we constructed a conductive composite hydrogel as a potential wound dressing through strategic incorporation of lignin (LS) and MXene nanosheets into a PVA matrix.

Peculiar Effect of Water on Tribological Properties of Natural Deep Eutectic Solvent.

Deep eutectic solvents (DESs) have emerged as promising green liquid lubricants for solving tribological problems due to their economic and excellent physicochemical and lubrication properties. However, a trace amount of water would affect their structure, physicochemical properties, and tribological properties. The effect of water on the tribological properties of DES is still unclear and needs further investigate.

Multi-scale microstructural construction in ultralight graphene aerogels enables super elasticity and unprecedented durability for impact protection materials.

Ultralight graphene aerogels have gained extensive recognition in the impact protection field. However, attaining both elasticity and durability at low material density is challenging due to their intrinsic conflicts. Inspired by the mantis ootheca, we present a simultaneous improvement in the elasticity, durability, and density restrictions of ultralight graphene aerogels via constructing a multiscale honeycomb microstructure (MHM) within the graphene skeleton.

Biodegradable polyvinyl alcohol/nano-hydroxyapatite composite membrane enhanced by MXene nanosheets for guided bone regeneration.

MXene, as a new category of two-dimensional nanomaterials, exhibits a promising prospect in biomedical applications due to its ultrathin structure and morphology, as well as a range of remarkable properties such as biological, chemical, electronic, and optical properties. In this work, different concentrations of MXene (M) were added to polyvinyl alcohol (PVA, P)/nano-hydroxyapatite (n-HA, H) mixed solution, and series of PVA/n-HA/MXene (PHM) composite membranes were obtained by combining sol-gel and freeze-drying processes. Morphology, chemical composition, surface, and mechanical properties of the prepared PHM membranes were characterized by various techniques.

MXene/Silk Fibroin Strengthened PVA-Based Eutectogel with Excellent Self-Healing Ability and Environmental Adaptability: Design, Synthesis, and Sensing Application.

A superelastic self-healing eutectogel was designed and prepared using poly (vinyl alcohol) (PVA) as the bulk skeleton material, while silk fibroin (SF) and two-dimensional (2D) MXene (TiCT) as reinforcing fillers. In brief, the eutectogel possesses a high tensile strength of 7.63 MPa, and its elongation at break reached 1115.

Influences of Ultrasonic Image-Guided Erector Spinae Plane Block on Postoperative Pulmonary Air Content of Lung Carcinoma Patients Undergoing Thoracoscopic Surgery.

To investigate the influences of ultrasonic image-guided erector spinae plane block (ESPB) on postoperative pulmonary air content of lung carcinoma patients undergoing thoracoscopic surgery, 42 patients performed with thoracoscopic radical surgery for lung carcinoma were selected. The patients in the experimental group were performed with ultrasound-guided unilateral ESPB and intravenous general anesthesia. The patients in the control group only underwent intravenous anesthesia.

Two-Dimensional Nanosheet-Enhanced Waterborne Polyurethane Eutectogels with Ultrastrength and Superelasticity for Sensitive Strain Sensors.

Sensing materials that are ultrastrong but still superelastic and highly sensitive are crucial for meeting the requirements of future flexible sensors. However, these requirements are challenging to satisfy simultaneously due to the internal constraints among these properties. Here, an ultrastrong and superelastic eutectogel is designed and prepared using a waterborne polyurethane (WPU) network enhanced by two-dimensional (2D) nanosheets in a deep eutectic solvent.

miR-489-3p promotes malignant progression of non-small cell lung cancer through the inactivation of Wnt/β-catenin signaling pathway via regulating USP48.

Background: Non-small cell lung cancer (NSCLC) is the most prevalent form of lung cancer globally, with average age of cancer patients becoming younger gradually. It is of significance to gain a comprehensive understanding of molecular mechanism underlying NSCLC.

Methods: Quantitative polymerase chain reaction (qPCR) and western blot were applied to measure RNA and protein levels separately.

Heat- and freeze-tolerant organohydrogel with enhanced ionic conductivity over a wide temperature range for highly mechanoresponsive smart paint.

Binary solvent-based fabrication permits the conductive organohydrogel to function well at low-temperature environments. However, the deep cryogenic and high temperatures are still threatening the performance of conductive organohydrogels in the application of stretchable electronics, biosensors, and intelligent coatings. Here, a radically new method is developed to introduce propylene and carbonate cellulose nanofibrils into freeze tolerance polymer matrix, and fabricate an antifreezing/antiheating organohydrogel integrated a high mechanical strength (1.

Conformational and rheological properties of bacterial cellulose sulfate.

In this study, a water-soluble bacterial cellulose sulfate (BCS) was prepared with sulfur trioxide pyridine complex (SO3· Py) in a lithium chloride (LiCl)/dimethylacetamide (DMAc) homogeneous solution system using bacterial cellulose (BC). The structural study showed that the value for the degrees of substitution of BCS was 1.23.

Antibacterial polyvinyl alcohol/bacterial cellulose/nano-silver hydrogels that effectively promote wound healing.

The lack of antibacterial properties limits the application of bacterial cellulose hydrogels in wound dressings. To overcome this deficiency, silver nanoparticles (AgNPs) were introduced as antibacterial agents into a polyvinyl alcohol (PVA)/bacterial cellulose (BC) solution. A freeze-thaw method promoted formation of PVA/BC/Ag hydrogels and improved their mechanical properties.

Ultralight GO-Hybridized CNTs Aerogels with Enhanced Electronic and Mechanical Properties for Piezoresistive Sensors.

Extremely low density carbon nanotubes/graphene hybrid aerogels (CNG) are highly potential active materials for fabricating flexible devices, owing to synergistic effects with one (nanotubes) and two (graphene) dimensional characters in a single structure. However, conquering the long-standing dilemma among low electronic conductivity and inferior mechanical properties for CNG remains a challenging task. Here, an ultralight CNG aerogel (1.

Circular RNA CHST15 Sponges miR-155-5p and miR-194-5p to Promote the Immune Escape of Lung Cancer Cells Mediated by PD-L1.

Background: The effects of up-regulated CircCHST15 on lung cancer remained unclear. In this study, the role of CircCHST15 in lung cancer was investigated.

Methods: Dual-luciferase reporter verified the bioinformatics prediction that CircCHST15 targeted miR-155-5p and miR-194-5p.

Synthesis and Adsorption Properties of Novel Bacterial Cellulose/Graphene Oxide/Attapulgite Materials for Cu and Pb Ions in Aqueous Solutions.

Removing heavy metal ions from industrial wastewater is one of the most important and difficult areas of the water treatment industry. In this study, Bacterial Cellulose/Polyvinyl Alcohol/Graphene Oxide/Attapulgite (BC/PVA/GO/APT) composites were successfully prepared via a repeated freeze-thaw method using bacterial cellulose, polyvinyl alcohol as the skeleton, and graphene oxide, attapulgite as fillers. The capacities of adsorbing Cu and Pb ions in solution were investigated.

Circular RNA TUBA1C accelerates the progression of non-small-cell lung cancer by sponging miR-143-3p.

Non-small-cell lung cancer (NSCLC) is one of the most common solid tumors and the leading cause of lung cancer-related fatality. Growing evidence has indicated that circular RNAs (circRNAs) play important roles in the progression of multiple human cancers. As a novel circRNA, very little research has focused on the function of circRNA TUBA1C (circTUBA1C) in cancer development, including NSCLC.

Room temperature readily self-healing polymer via rationally designing molecular chain and crosslinking bond for flexible electrical sensor.

Mechanically tough polymers with excellent room temperature self-healing capacity have aroused strong interest in soft electronics, electronic skins and flexible energy storage devices. However, achieving such polymers remains a challenge due to tardy diffusion dynamics. Herein, a robust and readily self-healing polymer, which is synthesized by one-pot polymerization among 2,4'-tolylene diisocyanate, isophorone diisocyanate, and poly(oxy-1,4-butanediyl), is achieved through reasonably tuning the hardness of the molecular segment and the strength of the dynamic crosslinking bond.

Robust, Stretchable, and Self-Healable Supramolecular Elastomers Synergistically Cross-Linked by Hydrogen Bonds and Coordination Bonds.

Polymeric elastomers integrated with high mechanical toughness and excellent self-healing ability can find attractive applications in electronic skin, soft robotics, and electrical devices. However, simultaneously enhancing the mechanical and self-healing properties of elastomers is still a great challenge because it is difficult to balance the effects between strong and weak cross-linking bonds. Here, a novel self-healing elastomer is developed via a one-pot polycondensation reaction between bis(3-aminopropyl)-terminated poly(dimethylsiloxane) and 2,4'-tolylene diisocyanate, followed by being coordinated with Al(III) ions by metal-coordination bonds.

Extremely elastic and conductive N-doped graphene sponge for monitoring human motions.

Due to the extraordinary properties of great elasticity, ultralow density, and good electrical conduction, macroporous graphene bulk materials are the promising candidate as the sensing materials for flexible electronics. Although a large number of progresses have been made, the piezoresistive effect of graphene does not completely meet requirements for various applications yet. Herein, the nitrogen-doped graphene sponge (NGS) material with well-ordered and uniform macroscopic porous structure in long range has been developed by a simple and low-cost strategy by combining hydrothermal and thermal annealing processes.

Reducing Structural Defects and Oxygen-Containing Functional Groups in GO-Hybridized CNTs Aerogels: Simultaneously Improve the Electrical and Mechanical Properties To Enhance Pressure Sensitivity.

Three-dimensional graphene oxide-carbon nanotube (GO-CNT, abbreviated as GCNT) aerogels can find wide applications in various fields. Especially, low-density GCNT aerogels featuring both high conductivity and superelasticity are essential requirements for the construction of highly sensitive pressure sensor. However, simultaneous improvement on the electrical and mechanical properties of low-density GCNT is still a great challenge owing to their disordered microstructure, severe structural defects and massive oxygen-containing functional groups.

In situ formation of spherical MoS nanoparticles for ultra-low friction.

The motion resistance and energy dissipation of rolling friction are much lower than those of sliding friction at the macroscale. But at the microscale, the impact of rolling on friction remains an open question. Here, we show that spherical MoS2 nanoparticles can be formed in situ at a friction interface by scrolling and wrapping MoS2 nanosheets under the induction of a reciprocating shear stress, when an MoS2 coating constructed from loosely stacked nanosheets is tested in a vacuum of 3.

High-Performance Graphene Sponges Reinforced with Polyimide for Room-Temperature Piezoresistive Sensing.

The bulk materials of three-dimensional graphene (3DG) with high network structure and excellent electrical conductivity have many potential applications in flexible electronics, but the network structure is not very stable due to weak bonding between graphene nanosheets. Here, a polyimide (PI) layer was introduced on the as-prepared 3DG sponge by vacuum infiltration-curing method. The resulting 3DG/PI composite sponges with robust 3D network structure exhibited an excellent electrical conductivity (3.

Fluorine Doping Strengthens the Lithium-Storage Properties of the Mn-Based Metal-Organic Framework.

The electrochemical properties of the metal-organic framework (MOF)-based composite as electrode material can be significantly improved by means of partial destruction of the full coordination of linkers to metal ions and replacing with other small ions, which make metal centers become more accostable and consequently more effective for the lithiation/delithiation process. In this paper, F was chosen to replace some of the benzenedicarboxylate (BDC) linkers because of its better interaction with the Li than the oxide ion. What's more, the formed M-F bond promotes the Li to transfer at the active material interface and protects the surface from HF attacking.

[Heterologous expression, purification and characterization of phospholipase C from Bacillus cereus in Kluyveromyces lactis].

Objective: In this study, we constructed recombinant Kluyveromyces lactis strains to produce phospholipase C (PLC) of Bacillus cereus. The recombinant enzymes were purified and characterized.

Methods: We cloned the PLC encoding gene bcplc of Bacillus cereus.