Overcoming the Catalytic Activity-Stability Trade-Off by an Electrified Chainmail Membrane Composed of Copper Nanowires Encapsulated by Reduced Graphene Oxide.

Overcoming the catalytic activity-stability trade-off remains a critical challenge for advanced oxidation processes (AOPs). Here, we fabricate an electrified chainmail membrane, composed of copper nanowires encapsulated by reduced graphene oxide (CuNW@rGO), exhibiting both high catalytic activity and long-term stability. The electrified CuNW@rGO membrane/peroxymonosulfate (PMS) system efficiently degrades various water contaminants, including dyes, pharmaceuticals, and phenolics (73-98%).

PMFF-Net: A deep learning-based image classification model for UIP, NSIP, and OP.

Background: High-resolution computed tomography (HRCT) is helpful for diagnosing interstitial lung diseases (ILD), but it largely depends on the experience of physicians. Herein, our study aims to develop a deep-learning-based classification model to differentiate the three common types of ILD, so as to provide a reference to help physicians make the diagnosis and improve the accuracy of ILD diagnosis.

Methods: Patients were selected from four tertiary Grade A hospitals in Kunming based on inclusion and exclusion criteria.

Cisplatin potentiates PD-L1 expression more robustly than pemetrexed in malignant pleural mesothelioma: Temporal dynamics revealed by cellular and xenograft analyses.

Objective: Chemotherapy may modulate PD-L1 expression in malignant pleural mesothelioma (MPM), influencing immune checkpoint inhibitor (ICI) efficacy. We compared cisplatin (CDDP) and pemetrexed (PEM) on PD-L1 dynamics in MPM.

Methods: H226 (epithelial) and MSTO-211H (biphasic) cells were treated with CDDP/PEM for 12-48 h, with apoptosis analyzed by flow cytometry and PD-L1 by Western blot.

Supramolecularly Confined Catalysis in Polyphthalocyanine-Crown-Ether Frameworks Boosts Sulfur Redox Kinetics.

Metal phthalocyanines are considered as potent catalysts in lithium-sulfur (Li-S) chemistry. However, their adsorption capability is deficient to inhibit polysulfides from shuttling, which in turn retards the S-redox reaction in the cathode. Here we report flexible, two-dimensional (2D) polyphthalocyanine-crown-ether (PPc-CE) frameworks that provide a supramolecularly confined space created with the single-atom catalytic nickel phthalocyanine nodes and crown-ether linkers as Li host.

A machine learning model for mortality prediction in patients with severe fever with thrombocytopenia syndrome: a prospective, multicenter cohort study.

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that imposes a considerable medical burden. In this study, we enrolled 1,606 SFTS patients, developed and validated machine learning models for mortality prediction, and ultimately constructed a model consisting of six variables. The prediction model, UNION-SFTS, constructed using the multilayer perceptron (MLP) algorithm, achieved the best performance with an area under the curve (AUC) of 0.

Heterogeneous Peroxymonosulfate-Based Advanced Oxidation Mechanisms: New Wine in Old Bottles?

Heterogeneous persulfate-based advanced oxidation processes (PS-AOPs) have been gaining significant attention in water/wastewater treatment; however, the elucidation of mechanisms in PS-AOPs has become increasingly complex as the understanding of potential reactive pathways expands and the rigor of corresponding characterizations intensifies. As such, accurately illustrating system mechanisms with a robust and convincing methodology is crucial, while the influence of substrates must not be overlooked. In this Perspective, established techniques and critical issues are systematically compiled to serve as practical guidelines.

Accentuation Affects the Planning Scope and Focus-Accentuation Consistency Modulates Sentence Production: Evidence From Eye Movements.

Purpose: Previous studies have shown that the planning scope of sentence production is flexible and influenced by a range of linguistic and extralinguistic factors. However, one important aspect that remains underexplored is the role of prosody, a key component of language, in shaping the planning scope. While it has been established that both conceptual and grammatical information influence sentence production and conceptual information is closely linked with prosodic cues, it remains unclear whether and how prosody, particularly accentuation, affects the planning process.

Linear incrementality in focus and accentuation processing during sentence production: evidence from eye movements.

Introduction: While considerable research in language production has focused on incremental processing during conceptual and grammatical encoding, prosodic encoding remains less investigated. This study examines whether focus and accentuation processing in speech production follows linear or hierarchical incrementality.

Methods: We employed visual world eye-tracking to investigate how focus and accentuation are processed during sentence production.

Detection of PD-L1 expression levels in malignant pleural mesothelioma with a targeted MRI nanoprobe .

Objectives: Immune checkpoint inhibitors (ICIs) have demonstrated potential in inhibiting the growth of malignant pleural mesothelioma (MPM), and their efficacy is associated with the expression of programmed death-ligand 1(PD-L1). This study evaluated a PD-L1-targeted nanoprobe for detecting PD-L1 expression in a nude mouse model of malignant pleural mesothelioma (MPM).

Methods: A PD-L1-binding peptide (WL-12) was conjugated with superparamagnetic iron oxide nanoparticles (SPIONs) to create the nanoprobe WL-12@Fe₃O₄.

Species mass transfer governs the selectivity of gas diffusion electrodes toward HO electrosynthesis.

The meticulous design of advanced electrocatalysts and their integration into gas diffusion electrode (GDE) architectures is emerging as a prominent research paradigm in the HO electrosynthesis community. However, it remains perplexing that electrocatalysts and assembled GDE frequently exhibit substantial discrepancies in HO selectivity during bulk electrolysis. Here, we elucidate the pivotal role of mass transfer behavior of key species (including reactants and products) beyond the intrinsic properties of the electrocatalyst in dictating electrode-scale HO selectivity.

Efficacy and safety of esketamine combined with propofol for conscious sedation in painless colonoscopy: a prospective, randomized, double-blind controlled clinical trial.

Background: We explored the efficacy and safety of esketamine combined with propofol for conscious sedation in painless colonoscopy.

Methods: A total of 195 patients who underwent painless colonoscopy surgery were randomly divided into three groups: the propofol deep sedation group (group DS), the sufentanil combined with propofol for conscious sedation (group CS) and the esketamine combined with propofol for conscious sedation (group CS). The primary outcomes of this study included the incidence of hypoxemia, hypotension, hypertension, and bradycardia and excellent and good rates of anaesthesia during colonoscopy.

Development of a bionic hexapod robot with adaptive gait and clearance for enhanced agricultural field scouting.

High agility, maneuverability, and payload capacity, combined with small footprints, make legged robots well-suited for precision agriculture applications. In this study, we introduce a novel bionic hexapod robot designed for agricultural applications to address the limitations of traditional wheeled and aerial robots. The robot features a terrain-adaptive gait and adjustable clearance to ensure stability and robustness over various terrains and obstacles.

Establishment of a Mouse Model for Porokeratosis Due to Mevalonate Diphosphate Decarboxylase Deficiency.

Introduction: Porokeratosis (PK) is an autoinflammatory keratinization disease (AIKD) characterized by circular or annular skin lesions with a hyperkeratotic rim, pathologically shown as the cornoid lamella. Four genes that cause PK are associated with the mevalonate (MV) pathway. In Chinese PK patients, mevalonate diphosphate decarboxylase (MVD) is the most common causative gene.

Evaluation of β2-microglobulin in the condition and prognosis of psoriasis patients.

Background: Numerous studies have linked the inflammatory pathway in psoriasis and metabolic disease, while no specific marker defined it. It is worth exploring the association of β2-microglobulin (β2M) in psoriasis severity and comorbidities.

Objectives: To investigate the correlation between blood β2M level and psoriasis severity, to explore the inflammatory factors influencing the occurrence of psoriasis comorbidities such as arthritis, diabetes, and hypertension.

The impact of farmers' participation in green cooperative production on green performance-A study based on the moderating effect of environmental regulation.

Based on 491 farmers joining in cooperatives microscopic data in Jiangxi Province,the paper uses Ordinary Least Squares to test the influence mechanism of cooperative green production on green performance, and takes environmental regulation as a regulatory variable to explore the relationship between cooperative green production and cooperative green performance. The results have shown that: (1) The green production cooperatives have a significant positive impact on their green performance, and the impact of green production on economic performance, social performance and ecological performance gradually strengthens from weak to strong; (2) Environmental regulations have a positive regulatory effect on the relationship between cooperative green production and cooperative green performance, among which three types of environmental regulations, namely, incentive, restraint and guided, can strengthen the positive relationship between green production and green performance.

Increased and sex-differentiated medial prefrontal cortex activation during the MATRICS Consensus Cognitive Battery in schizophrenia: A fNIRS study.

Executive impairment in schizophrenia is common, but the mechanism remains unclear. This is the first study to use simultaneously functional near-infrared spectroscopy (fNIRS) to monitor the hemodynamic response in schizophrenia during the MATRICS Consensus Cognitive Battery (MCCB). Here, we monitored relative changes in oxyhemoglobin concentration in the medial prefrontal cortex (mPFC) during Trail Making Test, Symbol Coding Test and Mazes Test of the MCCB in 63 patients (29 females) with schizophrenia and 32 healthy controls (15 females).

Identification of an exosomal miRNA-mRNA regulatory network contributing to methotrexate efficacy.

Objective: Methotrexate (MTX) is an economic and effective medicine treatment for psoriasis. Extracellular vesicle (EV) miRNA biomarkers related to its efficiency have been identified in various diseases. Whether certain miRNA profiles are associated with psoriasis treatment is unknown.

Lithium fluorosulfonate-induced low-resistance interphase boosting low-temperature performance of commercial graphite/LiFePO pouch batteries.

The performance of Li-ion batteries (LIBs) at sub-ambient temperatures is limited by the resistive interphases due to electrolyte decomposition, particularly on the anode surface. In this study, lithium fluorosulfonate (LFS) was added to commercial electrolytes to enhance the low-temperature electrochemical performance of LiFePO (LFP)/graphite (Gr) pouch cells. The addition of LFS significantly reduced the charge transfer resistance of the anode, substantially extending the cycle life and discharge capacity of commercial LFP/Gr pouch cells at -10 and -30 °C.

Is there a stronger willingness to pay for photovoltaic power generation with high education in China?

Adoption of clean electric energy depends not only on administrative regulations, but also on public support, in particular, the public is willing to pay for environmental improvements. However, the increase of solar photovoltaic power generation willingness to pay (WTP) associated with higher education attainment and the identification of their causality has been missing. Present paper used the enactment of the Compulsory Schooling Law as an instrumental variable to solve the causal relationship between education and willingness to pay for photovoltaic power generation.

AIE/AEE tripodal PEGyl-melphalan supramolecules and detection of trinitrophenol in water.

Herein, the design of a novel aggregation-induced emission (AIE) supramolecular fluorescence sensor (TA-PEG) based on a tridentate melphalan derivative and three different molecular weight PEGs is presented. The three TA-PEG sensors could self-assemble into a supramolecular system in water and show sensitive and selective responses toward trinitrophenol.

Functionalization of seawater reverse osmosis membrane with quorum sensing inhibitor to regulate microbial community and mitigate membrane biofouling.

Membrane biofouling is a challenge to be solved for the stable operation of the seawater reverse osmosis (SWRO) membrane. This study explored the regulation mechanism of quorum sensing (QS) inhibition on microbial community composition and population-level behaviors in seawater desalination membrane biofouling. A novel antibiofouling SWRO membrane (MA_m) by incorporating one of quorum sensing inhibitors (QSIs), methyl anthranilate (MA) was prepared.