Biochar-calcium alginate composite immobilizing Pseudomonas sp. H6 for phosphate and ammonium recovery: Multi-omics insights and practical application evaluation.

Water eutrophication has emerged as a pervasive ecological challenge worldwide. To realize the resource utilization of waste and nutrients, a novel rape straw-derived biochar-calcium alginate composite (M-CA-RBC) immobilized Pseudomonas sp. H6 was synthesized to simultaneously remove phosphate (PO) and ammonium (NH) from distillery wastewater.

Early-onset gastric cancer global burden profile, trends, and contributors.

Objective: This study aimed to assess the global, regional, and national burden of early-onset gastric cancer (EOGC) and the attributable risk factors from 1990-2021 with projections extending to 2040.

Methods: The EOGC burden was quantified using incidence, prevalence, mortality, and disability-adjusted life years (DALYs) with calculation of age-standardized rates. The risk factor contributions were analyzed and disparities were evaluated using the slope index of inequality.

Comparative proteomic profiles of tropical seagrass Thalassia hemprichii under contrasting nutrient and light conditions based on optimized protein extraction and identification.

Limitations in efficient protein extraction and identification hinder proteomic studies in seagrasses. Using optimized extraction and identification methods, comparative proteomic profiles of tropical seagrass T. hemprichii under contrasting nutrient and light conditions were examined.

Association between serum corin in the second trimester and hypertensive disorders of pregnancy: a mendelian randomization study.

Background: Serum corin has been associated with hypertensive disorders of pregnancy (HDP) in clinical studies but lacks causal evidence. This study aimed to systemically examine the associations of serum corin and its coding gene polymorphisms with HDP, as well as the underlying causality among Chinese pregnant women.

Methods: A nested case-control study comprising 403 cases of HDP and 402 age- and parity-matched healthy controls was designed.

Mixed matrix membrane of Pebax-1657 incorporated with HO-modified ball-milled biochar for enhanced CO separation.

Biochar derived from wheat straw was prepared and subsequently modified with hydrogen peroxide through ball milling, yielding ball-milled wheat straw biochar (BMWB). BMWB/Pebax mixed matrix membranes (MMMs) were prepared by incorporating BMWB into Pebax-1657, and their CO separation performance was evaluated. The results showed that ball milling successfully reduced the biochar particle size, increased its specific surface area, and strengthened the intensity of surface functional groups.

Clinical observation of pyogenic granuloma treated with combined long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser photodynamic therapy.

To explore the clinical efficacy and safety of long-pulse 1064nm Nd: YAG laser combined with pulsed CO2 laser and topical application of aminolevulinic acid hydrochloride for photodynamic therapy in treating pyogenic granuloma. 20 patients with pyogenic granuloma were treated with a combination of long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser along with photodynamic therapy using aminolevulinic acid hydrochloride. The efficacy, recurrence rate, and safety were observed at 1 month and 2 months post-treatment.

Poor clinical outcomes in respiratory viral sepsis: a retrospective observational study.

Aim: This study attempts to explore the clinical differences of sepsis caused by respiratory viruses and bacteria, and to search for risk factors for mortality in viral sepsis.

Methods: This single-centre, retrospective cohort study enrolled patients hospitalised at our medical intensive care unit (ICU) from October 2020 to January 2024 who were diagnosed with pneumonia and sepsis. The primary and secondary pathogens were identified with comprehensive aetiological tests.

YOLO-TARC: YOLOv10 with Token Attention and Residual Convolution for Small Void Detection in Root Canal X-Ray Images.

The detection of small voids or defects in X-ray images of tooth root canals still faces challenges. To address the issue, this paper proposes an improved YOLOv10 that combines Token Attention with Residual Convolution (ResConv), termed YOLO-TARC. To overcome the limitations of existing deep learning models in effectively retaining key features of small objects and their insufficient focusing capabilities, we introduce three improvements.

Characterization of a novel 1,2-dichloroethane degrader Ancylobacter sp. J3 and use of its immobilized cells in the treatment of polluted groundwater.

A novel 1,2-dichloroethane (1,2-DCA) degrading bacteria strain J3 was isolated from 1,2-DCA contaminated groundwater and identified as Ancylobacter sp. The strain J3 was associated with self-flocculation during the growth process, and the degradation pathway study showed that the bacteria could completely mineralize 1,2-DCA. The microorganism was immobilized and the optimum preparation conditions were obtained by orthogonal experiment: 6 % polyvinyl alcohol, 2 % sodium alginate, 1 % biochar, and 2 % CaCl and the immobilized cells were named J3C.

A pilot study on an infrared jaw-tracking method for mandibular motion based on modified bite-fork registration: Accuracy and feasibility.

Objectives: This study developed a novel method for repeated tracking without requiring secondary cone-beam computed tomography (CBCT) exposure or additional registration operations.

Methods: An infrared jaw-tracking method based on the registration of a modified bite-fork was developed. The accuracy of the method was evaluated by comparing head-simulator linear distance measurements obtained using the jaw-tracking and CBCT imaging methods and calculating the root mean square (RMS) errors associated with linear distance deviations.

Deep-learning network for automated evaluation of root-canal filling radiographic quality.

Background: Deep-learning networks are promising techniques in dentistry. This study developed and validated a deep-learning network, You Only Look Once (YOLO) v5, for the automatic evaluation of root-canal filling quality on periapical radiographs.

Methods: YOLOv5 was developed using 1,008 periapical radiographs (training set: 806, validation set: 101, testing set: 101) from one center and validated on an external data set of 500 periapical radiographs from another center.

The conditions that patients with systemic lupus erythematosus should fulfill before pregnancy to optimize outcomes: a large-scale multicenter cohort study from China.

Background: Systemic lupus erythematosus (SLE) is frequently associated with a lower rate of live birth and a higher incidence of adverse pregnancy outcomes (APOs), and pregnancy can also increase the risk of SLE flares. Comprehensive preconception assessment is critical for improved pregnancy outcomes in patients with SLE. Unfortunately, no global consensus on the conditions that patients with SLE should fulfill prior to pregnancy has yet been formed.

Risk and protective factors of disease flare during pregnancy in systemic lupus erythematosus: a systematic review and meta-analysis.

To synthesize available evidence on predictive factors associated with systemic lupus erythematosus (SLE) flares during pregnancy, we systematically searched MEDLINE, Embase, and the Cochrane Library through January 2024 for observational studies on risk and protective factors of SLE flares during pregnancy. Odds ratios (OR) and mean differences (MD), as well as their 95% confidence intervals (CI) were used to quantify effect sizes. We employed fixed-effect or random-effect models based on heterogeneity assessments (I statistics).

Periodontitis Exacerbates Colorectal Cancer by Altering Gut Microbiota-Derived Metabolomics in Mice.

Aim: The correlation between periodontitis and colorectal cancer (CRC) has drawn widespread attention. However, how periodontitis affects CRC progression remains unclear.

Methods: C57BL/6 mice were used to establish experimental periodontitis and CRC model.

Feasibility of occlusal plane in predicting the changes in anteroposterior mandibular position: a comprehensive analysis using deep learning-based three-dimensional models.

Background: A comprehensive analysis of the occlusal plane (OP) inclination in predicting anteroposterior mandibular position (APMP) changes is still lacking. This study aimed to analyse the relationships between inclinations of different OPs and APMP metrics and explore the feasibility of OP inclination in predicting changes in APMP.

Methods: Overall, 115 three-dimensional (3D) models were reconstructed using deep learning-based cone-beam computed tomography (CBCT) segmentation, and their accuracy in supporting cusps was compared with that of intraoral scanning models.

Triplet Electron Exchange in Carbon Nanodots-assisted Long-persistent near-infrared Chemiluminescence for Oncology Synergistic Imaging and Therapy.

In classical photodynamic therapy, tumor cells are killed by the cytotoxic species via type-I/II photochemical reactions, seriously limited by the external photoexcitation and hypoxia. Herein, the electron transfer mechanism between fluorophores and peroxalate-HO reaction is investigated and the singlet/triplet electron exchange is utilized to achieve long-persistent chemiluminescence imaging and synergistic type-I/II/III photodynamic therapy. As a proof-of-concept, the photosensitizers of carbon nanodots (CDs)-loaded chlorin e6 (CDs-Ce6) are designed and integrated with the peroxalate molecules, and the as-prepare polymer carbon nanodots (p-CDs) exhibit novel tumor microenvironment (TME)-responsive long-persistent near-infrared CL and photochemical reactions, evoking the in vivo imaging and synergistic dynamic therapy in tumor tissue.

Total parietal peritonectomy and multivisceral resection for extensive cytoreductive surgery in pseudomyxoma peritonei: En bloc "Rolled-up carpet" technique and perioperative and oncologic outcomes.

Background: Patients diagnosed with pseudomyxoma peritonei (PMP) of appendiceal origin typically present with high tumor burden and require extensive cytoreductive surgery (CRS) to achieve optimal cytoreduction. This study describes an en bloc "rolled-up carpet" surgical technique for total parietal peritonectomy and multivisceral resection while also analyzing the perioperative and tumor outcomes of this technique.

Methods: The study reviewed the data of 7 patients underwent en bloc "rolled-up carpet" extensive CRS between August 2020 and April 2023.

Remediation of antimony and arsenic in co-contaminated soil by electrolytic manganese residue-biochar composite: Effects, mechanisms, and microbial response.

Antimony (Sb) mining and smelting activities caused Sb and arsenic (As) pollution in the soil, posing a threat to the ecosystem and human health. To remediate Sb and As in co-contaminated soil and realize the resource utilization of typical industrial solid waste, electrolytic manganese residue (EMR)-biochar composite (EB) was prepared from EMR and distillers grains by a facile one-step pyrolysis method. The immobilization effect of EB on Sb and As in soil was studied using a column leaching experiment.

Calcium alginate-biochar composite immobilized A. ferrooxidans effectively removes sulfate and ferric iron from acid mine drainage.

Bioremediation has been applied in the treatment of acid mine drainage (AMD), but high levels of sulfate (SO) and ferric iron (Fe) in AMD often affect microbial activity. A novel biochar-microorganism composite (I-CMR600) was developed by alginate gel-embedding method to improve the tolerance of microorganisms and the removal effects of SO and Fe in AMD, and its removal mechanism and biological behavior were explored in this study. The removal performance of I-CMR600 under different influencing factors was studied by batch adsorption experiments.

Multifaceted role of nanocomposite hydrogels in diabetic wound healing: enhanced biomedical applications and detailed molecular mechanisms.

The complex microenvironment of diabetic wounds, which is characterized by persistent hyperglycemia, excessive inflammatory responses, and hypoxic conditions, significantly impedes the efficacy of traditional hydrogels. Nanocomposite hydrogels, which combine the high-water content and biocompatibility of hydrogels with the unique functionalities of nanomaterials, offer a promising solution. These hydrogels exhibit enhanced antibacterial, antioxidant, and drug-release properties.

Biochar coupled with multiple technologies for the removal of nitrogen and phosphorus from water: A review.

Water eutrophication caused by nitrogen (N) and phosphorus (P) has become a global environmental issue. Biochar is a competent adsorbent for removing N and P from wastewater. However, compared with commercial activated carbon, biochar has relatively limited adsorption capacity.

Feasibility and value of modular splenic hilar lymphadenectomy technique in laparoscopic total gastrectomy: a retrospective-controlled research.

Background: This study aims to investigate the feasibility and value of modular splenic hilar lymphadenectomy (MSHL) in LTG for advanced PGC located at the greater curvature.

Study Design: A retrospective-controlled research included 54 patients diagnosed with advanced PGC located at the greater curvature who underwent LTG combined with spleen-preserving hilar lymphadenectomy between January 2020 and December 2022 at the same treatment center. A total of 20 patients underwent classic splenic hilar lymphadenectomy (CSHL) using a medial approach (classic group), while 34 patients underwent MSHL (modular group).

The malnutrition in AECOPD and its association with unfavorable outcomes by comparing PNI, GNRI with the GLIM criteria: a retrospective cohort study.

Introduction: The management of nutritional risk has garnered significant attention in individuals diagnosed with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) due to the high prevalence of malnutrition and its correlation with unfavorable outcomes. While numerous rating scales exist to assist in assessment for both clinical and research purposes, there is considerable variability in the selection of scales based on the characteristics of the study participants and the study design. The objective of this study was to examine the efficacy of the Geriatric Nutritional Risk Index (GNRI) and Prognostic Nutritional Index (PNI) in identifying malnutrition and predicting prognosis in elderly AECOPD patients.

Impact of corticosteroids on initiation and half-year durability of humoral response in COVID-19 survivors.

Background: The impact of corticosteroids on humoral responses in coronavirus disease 2019 (COVID-19) survivors during the acute phase and subsequent 6-month period remains unknown. This study aimed to determine how the use of corticosteroids influences the initiation and duration of humoral responses in COVID-19 survivors 6 months after infection onset.

Methods: We used kinetic antibody data from the lopinavir-ritonavir trial conducted at Jin Yin-Tan Hospital in January 2020, which involved adults hospitalized with severe COVID-19 (LOTUS, ChiCTR2000029308).

Ventricular dysfunction consequences of mechanical dyssynchrony in isolated complete right bundle branch block versus left bundle branch block.

Background: Complete bundle branch block in individuals without structural heart disease is known as isolated complete bundle branch block. Isolated complete left bundle branch block (CLBBB) is correlated with ventricular dysfunction secondary to dyssynchrony; however, few studies have investigated isolated complete right bundle branch block (CRBBB), which was previously considered benign but was recently found to be associated with adverse cardiovascular outcomes. This study aimed to evaluate cardiac mechanical synchrony, and systolic and diastolic function in patients with isolated CRBBB and compare cardiac synchrony and function to patients with isolated CLBBB.