Accelerating iron redox cycling via acetate modification: a ligand engineering for sustainable fenton-like oxidation.

Accelerating the rate-limiting surface Fe(III)/Fe(II) redox cycling is pivotal for efficient iron-mediated Fenton-like decontamination, yet conventional reductants (e.g., toxic hydroxylamine, thiosulfate) suffer from secondary toxicity, self-quenching, and heavy metal leaching.

Latent Profile Analysis for Patient Activation in Patients with Essential Hypertension.

Purpose: Hypertension constitutes a significant global health issue, requiring active patient participation in self-management and health-related behaviors. Patient activation is defined as the knowledge, skills, and confidence in the management of their health. Prior studies have primarily employed total-score methods, potentially overlooking the variability in patient engagement.

Analysis of the Differences in Rhizosphere Microbial Communities and Pathogen Adaptability in Chili Root Rot Disease Between Continuous Cropping and Rotation Cropping Systems.

In chili cultivation, obstacles to continuous cropping significantly compromise crop yield and soil health, whereas crop rotation can enhance the microbial environment of the soil and reduce disease incidence. However, its effects on the diversity of rhizosphere soil microbial communities are not clear. In this study, we analyzed the composition and characteristics of rhizosphere soil microbial communities under chili continuous cropping (CC) and chili-cotton crop rotation (CR) using high-throughput sequencing technology.

Comparative Investigation of Single-Crystalline and Polycrystalline NaNiFeMnO Positive Materials for Sodium-Ion Batteries.

Layered oxide positive materials (NaTMO) for sodium-ion batteries have received widespread attention due to their advantages of high tap density, high theoretical specific capacity, and easy scale-up preparation. However, the current research about single-crystalline and polycrystalline materials is very limited, and the effect of the single-crystalline and polycrystalline structures on the electrochemical performance is still unclear. Based on this, NaNiFeMnO (NFM111) is used as the basic system to systematically investigate in depth the single-crystalline and polycrystalline positive materials.

Proteomic profiling reveals distinct inflammatory and neurogenic endotypes in rosacea.

Background: Rosacea represents a chronic inflammatory dermatosis with potential systemic manifestations. While neuroimmune dysregulation and systemic inflammation are implicated in its pathogenesis, comprehensive proteomic profiling remains unexplored.

Objective: To characterize serum proteomic signatures and identify molecular endotypes in rosacea.

Granulated straw incorporation with rotary tillage increases the content of soil organic carbon fractions and available nutrients and shifts bacterial communities in East China.

Introduction: Granulated straw incorporation is a novel approach designed to enhance straw decomposition and improve soil fertility. However, the effects of different straw incorporation amounts under deep tillage and rotary tillage on soil available nutrients, soil organic carbon (SOC) fractions, bacterial communities, and crop yield remain unclear.

Methods: In a 3-year field experiment, three granulated maize straw amounts (G1, 2,250; G2, 4,500; and G3, 6,750 kg hm) and two tillage methods (T, deep tillage; and R, rotary tillage) were applied to evaluate their impacts on SOC fractions, available nutrients, bacterial communities, and flue-cured tobacco yield.

Loneliness mediates the association between sleep deficiency and fighting in school-aged adolescents: a 2-year longitudinal study.

Sleep deficiency is becoming increasingly common among adolescents and may lead to aggressive behaviour. This study investigated the association between sleep deficiency and fighting among 1946 school-aged adolescents (mean age: 12.2 ± 0.

A 2-nm mode-hop-free tunable 1018-nm DBR single-frequency low-noise fiber laser.

This paper presents a comprehensive optimization of tuning capability and noise characteristics in 1018-nm distributed Bragg reflector (DBR) single-frequency fiber lasers. By implementing an advanced doped fiber design and a dual-stage precision thermal control system, for the first time, we demonstrate a fusion-spliced DBR fiber laser incorporating an 8-mm Yb-doped fiber that achieves >2 nm mode-hop-free continuous tuning across an extended temperature range of -20 °C to 175 °C. The integration of a piezoelectric transducer (PZT) tuning mechanism enables rapid frequency adjustment with a 10-GHz tuning bandwidth.

Fluorescence sensing of berberine hydrochloride via ns-Q[10]-based supramolecular assembly.

A sensing strategy to significantly enhance the aggregation-induced emission (AIE) of berberine hydrochloride (BBR) is proposed. A supramolecular framework material was prepared by using 5-sulfosalicylic acid (SSA) and nor-seco-cucurbit[10]uril (ns-Q[10]). Single crystal structure analysis confirmed that the SSA@ns-Q[10] assembly forms a ternary complex.

Prediction of risk factors associated with the development of multidrug-resistant tuberculosis in patients with tuberculosis.

Objective: This study aimed to develop and validate a reliable nomogram based on clinical factors to predict development of multidrug-resistant tuberculosis (MDR-TB) associated with individuals with tuberculosis (TB), so as to reduce the harm and economic burden caused by disease progression.

Methods: The study included 4,251 individuals with TB who received treatment at Huzhou Central Hospital between January 2016 and December 2023, excluding 87 individuals because of infection with non-TB mycobacterium or incomplete information (including missing laboratory or clinical data). A total of 4,164 individuals (2,261 sputum smear-positive and 1,903 sputum smear-negative patients) were ultimately included in the analysis.

Discovery of -(1,3,4-Thiadiazol-2-yl)amide Derivatives as Uncompetitive Inhibitors of 6-Phosphogluconate Dehydrogenase.

6-Phosphogluconate dehydrogenase (6PGD) is a crucial enzyme in the pentose phosphate pathway and a promising target for oncotherapy. However, potent 6PGD inhibitors remain limited. Herein, we report a series of -(1,3,4-thiadiazol-2-yl)amide derivatives as 6PGD inhibitors, via enzymatic assay-based high-throughput screening and structure-activity relationship analysis.

Boosting carrier separation over ultrathin g-CN by P doping for enhanced photocatalytic performance.

In light of the escalating severity of water pollution, the development of innovative and efficient photocatalytic materials has emerged as an urgent requirement. In this study, P-doped ultrathin g-CN was successfully synthesized using the chemical vapor deposition technique, specifically to enhance the photocatalytic degradation of the antibiotic tetracycline hydrochloride (TC) and the dye rhodamine B (RhB). The purpose of P doping was to modify the electronic structure of g-CN and increase its photocatalytic efficiency.

Does Pseudo-Lymph Node Skip Metastasis After Neoadjuvant Therapy Affect Esophageal Squamous Cell Carcinoma Outcomes? A Multicenter Study.

Background: Unlike classical lymph node skip metastasis, pseudo-lymph node skip metastasis occurs when proximal lymph nodes show therapeutic alleviation, while distal lymph nodes remain positive in esophageal squamous cell carcinoma after neoadjuvant therapy.

Objective: This multicenter study aimed to investigate the prognostic value of pseudo-lymph node skip metastasis.

Methods: We analyzed 1030 patients with esophageal cancer treated with neoadjuvant therapy followed by esophagectomy at three tertiary centers in China from 2010 to 2023.

Asymmetric Mn/Fe Dual Single-Atom Catalysts for pH-Universal Oxygen Electroreduction and Sustainable Metal-Air Batteries.

Conquering the sluggish kinetics of the oxygen reduction reaction (ORR) is significantly important for sustainable metal-air batteries. However, the synthesis of advanced Pt-free ORR electrocatalysts still remains challenging owing to the intrinsic activity, site accessibility, and structural stability. Herein, a catalyst of asymmetric N, P-coordinated Mn and Fe dual single atoms supported on hollow carbon polyhedra (MnFe-PNC) is synthesized via a metal-organic framework pyrolysis strategy, which displays excellent pH-universal ORR performance with half-wave potentials of 0.

Stereoacuity and ocular-associated factors in children aged 3-7 years in Guangxi, Southwest China: a cross-sectional study.

Objective: This study aimed to investigate the distribution of stereoacuity and its ocular-associated factors in children aged 3-7 years in Guangxi, Southwest China.

Methods: This cross-sectional study recruited 4,090 children aged 3-7 years (mean: 5.12 ± 0.

Prediction of the Low-Velocity Collision Response Characterization of a Plate Structure Considering the Strain Hardening Effect.

The prediction of the low-velocity collision response of a plate has substantial engineering significance. This paper presents a study to predict the low-velocity collision response characterization of a plate considering the strain hardening effect struck by a rigid sphere. To investigate the efficiency of the collision characterization diagram (CCD) based on the theoretical contact stiffness in characterizing the collision response case and calculating the maximum collision force, the intensive collision cases considering the strain hardening effect are implemented by the finite element (FE) method.

Depletion of Fat Mass and Obesity-Associated Protein (FTO) Drives Heterochromatin Loss via Lysine Acetyltransferase 8 (KAT8)-Mediated Remodeling and Spacing Factor 1 (RSF1) Acetylation in Skin Aging.

N6-methyladenosine (m6A), as the most common RNA modification at the post-transcriptional level, plays a role in various pathophysiological processes. However, its underlying mechanism in skin aging remains enigmatic. Here, we identified that fat mass and obesity-associated protein (FTO) serves as a protective factor against skin aging.

Targeting the ROCK2/UBA52/DRP1 axis enhances ferroptosis and overcomes pemigatinib resistance in Cholangiocarcinoma.

Cholangiocarcinoma (CCA) is a highly aggressive cancer that arises from the bile duct and has an extremely poor prognosis. Pemigatinib is the only Food and Drug Administration (FDA)-approved CCA-targeted drug. The CCA treatment options are insufficient considering its poor prognosis and increasing morbidity.

A turn-on supramolecular probe for visible detection and accurate identification of phenethylamine with orange emission.

The supramolecular fluorescent probe exhibited promising application in the field of detection and analysis, but developing supramolecular fluorescent probes with long wavelength emission and enhancement functions for the detection of phenylethylamines is a challenge. In this work, the guest molecule SPn with a D-π-A structure was designed and synthesized, and supramolecular fluorescent probe (SPn/Q[8]) with long wavelength emission was constructed by the host-guest interaction with cucurbit[8]uril (Q[8]). This probe detects phenethylamines based on an indicator displacement assay, which is a process characterized by a fast effect rate (within 6.

The hidden impact of myopia severity on interocular suppression in myopia: a cross-sectional study.

Objective: This study aimed to investigate the association between spherical equivalent (SE) and interocular suppression in myopic adults, addressing the knowledge gap in functional visual impairments beyond structural changes.

Methods: This hospital-based cross-sectional study included 988 myopic patients (aged 18.0-48.

DGHNN: a deep graph and hypergraph neural network for pan-cancer related gene prediction.

Motivation: Studies on pan-cancer related genes play important roles in cancer research and precision therapy. With the richness of research data and the development of neural networks, several successful methods that take advantage of multiomics data, protein interaction networks, and graph neural networks to predict cancer genes have emerged. However, these methods also have several problems, such as ignoring potentially useful biological data and providing limited representations of higher-order information.

Sequential Separation of Metal Cations Using Nor-seco-cucurbit[10]uril as a Supramolecular Material.

The treatment of metal-bearing wastewater is a critical step in safeguarding aquatic ecosystems and human health. In this study, the coordination characteristics of --cucurbit[10]uril (-Q[10]) were systematically examined with various metal cations, encompassing alkali metal, alkaline earth metal, and rare earth metals, in HCl aqueous solution. Through X-ray single-crystal diffraction analysis, 12 distinct -Q[10]-based coordination complexes were identified, incorporating Ca, Y, La, Ce, Pr, Sm, Eu, Gd, Tb, Dy, Ho, and Er metal ions.

Room-Temperature phosphorescent materials constructed based on Cucurbit[8]uril for encryption and anti-counterfeiting.

In this study, a supramolecular assembly composed of cucurbit[8]uril (Q[8]) and 6-bromoisoquinoline derivative (BI-BOH) was constructed. The 6-bromoisoquinoline moiety of BI-BOH entered the hydrophobic cavity of Q[8], forming a 1:2 assembly Q[8]-BI-BOH, with a relatively low level (ΔE = 0.03 eV), strengthening the intersystem crossing (ISC) process between the singlet state and the triplet state.

Pyrogenic Carbon Enhances Hydroxyl Radical Generation during Microbial Transformation of Ferrihydrite at Redox Interfaces.

Pyrogenic carbon (PC) is redox-active and facilitates the microbial reduction of Fe(III) (oxyhydr)oxides to Fe(II) under conditions. The oxygenation of Fe(II) under conditions produces hydroxyl radicals (OH). However, the influence of PC on this process remains largely unknown.