Variation characteristics and driving factors of vegetation coverage in Longquan Urban Forest Park, Chengdu, China.

Urban forest parks play a pivotal role in maintaining urban ecological security. The dynamics in fractional vegetation coverage (FVC) are key indicators for evaluating their ecological restoration effectiveness and sustainable management. Based on normalized difference vegetation index data of Chengdu Longquan Mountain Urban Forest Park from Landsat satellites spanning from 1993 to 2023, we used a comprehensive suite of analytical methods including Theil-Sen median slope estimation, Median-Kendall trend tests, additive seasonal and trend breakpoint detection, and the optimal partial geo-detector model (OPGD) to analyze both linear and nonlinear spatiotemporal variations of FVC within the park as well as driving factors.

Experimental study on the mechanical properties and deformation failure characteristics of sandstone under graded equal amplitude cyclic loading and unloading.

To investigate the effects of graded equal amplitude cyclic loading on rock deformation and failure, this study examines the influence of confining pressure and upper limit cyclic stress on the deformation parameters, stress-strain hysteresis curves, and macroscopic failure characteristics of sandstone during cyclic loading and unloading processes. Through a series of three-stage cyclic loading and unloading tests conducted under varying confining pressures, the findings indicate the following. With the increase of confining pressure and upper limit stress, the axial hysteretic loop of cyclic loading and unloading shows a tendency of expansion, and the hysteresis loop gradually changes from dense to sparse.

Restoring p53 wild-type conformation in TP53-Y220C-mutant acute myeloid leukemia.

TP53-Y220C is a recurrent hotspot mutation in cancers and leukemias. It is observed predominantly in acute myeloid leukemia (AML)/myelodysplastic syndromes among hematological malignancies and is associated with poor outcome. The mutation creates a structural pocket in the p53 protein.

The histidine kinase PhpA regulates the biocontrol activity of Pseudomonas bijieensis 2P24 through the Gac/Rsm signaling pathway.

Background: Histidine kinases in rhizosphere bacteria regulate physiological behaviors through two-component systems (TCSs) in response to environmental cues. The RetS-GacS/GacA multikinase network is critical for 2,4-diacetylphloroglucinol (2,4-DAPG) production and biocontrol activity in Pseudomonas bijieensis 2P24. However, the involvement of additional histidine kinases in this regulatory pathway remains unclear.

Biomechanical analysis of posterior, transforaminal, extreme, oblique, and anterior lumbar interbody fusion surgical models: a finite element study.

Many lumbar interbody fusion methods have been proposed, but there is a relative scarcity of fundamental biomechanical research on these varied surgical procedures. In this study, a finite element model of an L4-L5 functional spinal unit was created and five interbody fusion methods were evaluated, including posterior lumbar interbody fusion (PLIF), transforaminal lumbar interbody fusion (TLIF), extreme lateral interbody fusion (XLIF), oblique lateral interbody fusion (OLIF) and anterior lumbar interbody fusion (ALIF). Static and harmonic vibration surgery analysis models were developed based on it, investigating the biomechanical properties, as well as the variation of strain energy.

Interspecies hydrogen transfer between cyanobacteria and symbiotic bacteria drives nitrogen loss.

The trace concentration of H in most ecosystems after the Earth's oxidation has long caused the neglect of hydrogenotrophic denitrification for nitrogen loss. Here, we find that the interspecies hydrogen transfer between cyanobacteria and symbiotic bacteria within cyanobacterial aggregates is an undiscovered pathway for nitrogen loss. Cyanobacteria in aggregates can actively generate H under the diel cycle as an electron donor for neighboring hydrogenotrophic denitrifiers.

Computational modeling of biomechanical response of osteocyte integrin and cytoskeleton based on the piezoelectricity of bone matrix.

Osteocytes are key in bone remodeling, responding to mechanical stimuli. The piezoelectric bone matrix converts these stimuli into electrical signals, influencing remodeling. To delve deeper into this, we created an osteocyte model within a piezoelectric bone matrix, incorporating the lacuna-canalicular system and mechanosensors such as integrins, cytoskeleton, and primary cilia.

Spatial distribution characteristic, source apportionment, and risk assessment of heavy metals in the soil of an urban riparian zone.

The environmental quality of urban riparian soil has an impact on the riparian ecosystem and human health. The riparian zone of the Fen River plays an important ecological function in Taiyuan city and many residents and tourists enjoy recreational activities in Fen River Park. Therefore, environmental quality of the riparian zone is closely related to the health of residents.

A finite element study of the biomechanics of aging osteocyte model.

Aging lacuna-canalicular system (LCS) has osteocyte size reduction, cell process number loss, and canaliculus blockage. This study built four osteocyte aging models for various aging features. These models have processes, collagen hillocks, and primary cilia mechanoreceptors for signal comparison.

Polyyne production is regulated by the transcriptional regulators PgnC and GacA in Pf-5.

Polyynes produced by bacteria have promising applications in agriculture and medicine due to their potent antimicrobial activities. Polyyne biosynthetic genes have been identified in and . However, the molecular mechanisms underlying the regulation of polyyne biosynthesis remain largely unknown.

Design of fish-scale microstructured stents and their biomechanical effects on cerebral aneurysm.

The addition of microstructures to the inner surface of the stent reduces resistance and inhibits the phenomenon of blood adhesion. In this study, the design of a fish-scale microstructured vascular stent was proposed based on bionics, and its main design parameters were optimized using the finite element method. In addition, the hemodynamic effects of a standard stent and a fish-scale microstructured stent on an ideal cerebral aneurysm were comparatively analyzed.

Experimental investigation on the reverse mechano-electrical effect of porcine articular cartilage.

Introduction: The electric signals within the cartilage tissue are essential to biological systems and play a significant role in cartilage regeneration. Therefore, this study analyzed and investigated the reverse mechano-electrical effect in porcine articular cartilage and its related influencing factors.

Methods: The deflection of cartilage samples in an electric field was measured to analyze the mechanisms of different factors affecting the reverse mechano-electrical effect in articular cartilage.

Siderophore-Mediated Cooperation in Anammox Consortia.

It has been widely accepted that iron plays an important role in stimulating the activity of anammox bacteria, which contain many iron clusters for electron transport in cells. However, whether anammox bacteria could directly use and how to uptake Fe(III) have been long-time ignored. Here, we found that micrometer-scale magnetite with the size of 10-20 μm significantly promoted the anammox bacterial activity by iron core and iron uptake.

Heterogeneous Activation of NaClO by Nano-CoMnO Spinel for Methylene Blue Decolorization.

In this study, the nano-spinel CoMnO was synthesized by coprecipitation pyrolysis and employed to heterogeneously activate hypochlorite (NaClO) for the oxidative decolorization of methylene blue (MB). The crystal structure, elemental composition, surface morphology, and microstructure of the prepared CoMnO nano-spinel were analyzed using a series of characterization techniques. The pyrolysis temperature was screened on the basis of MB decolorization efficiency and the leaching of metal ions during the reaction.

Research progress on intervertebral disc repair strategies and mechanisms based on hydrogel.

Intervertebral disc degeneration (IDD) arises from a complex interplay of genetic, environmental, and age-related factors, culminating in a spectrum of low back pain (LBP) disorders that exert significant societal and economic impact. The present therapeutic landscape for IDD poses formidable clinical hurdles, necessitating the exploration of innovative treatment modalities. The hydrogel, as a biomaterial, exhibits superior biocompatibility compared to other biomaterials such as bioceramics and bio-metal materials.

Relationship between CTF1 gene expression and prognosis and tumor immune microenvironment in glioma.

Objective: This study aimed to evaluate CTF1 expression in glioma, its relationship to patient prognosis and the tumor immune microenvironment, and effects on glioma phenotypes to identify a new therapeutic target for treating glioma precisely.

Methods: We initially assessed the expression of CTF1, a member of the IL-6 family, in glioma, using bioinformatics tools and publicly available databases. Furthermore, we examined the correlation between CTF1 expression and tumor prognosis, DNA methylation patterns, m6A-related genes, potential biological functions, the immune microenvironment, and genes associated with immune checkpoints.

Multiscale interstitial fluid computation modeling of cortical bone to characterize the hydromechanical stimulation of lacunar-canalicular network.

Bone tissue is a biological composite material with a complex hierarchical structure that could continuously adjust its internal structure to adapt to the alterations in the external load environment. The fluid flow within bone is the main route of osteocyte metabolism, and the pore pressure as well as the fluid shear stress generated by it are important mechanical stimuli perceived by osteocytes. Owing to the irregular multiscale structure of bone tissue, the fluid stimulation that lacunar-canalicular network (LCN) in different regions of the tissue underwent remained unclear.

Occurrence characteristics and ecological impact of agricultural soil microplastics in the Qinghai Tibetan Plateau, China.

Plastic mulch is widely recognized as a significant contributor to microplastics (MPs) pollution in agricultural soil. However, its direct impact on remote areas with low population density remains uncertain due to multiple pollution sources. This study aims to investigate MPs pollution and its risks regarding agricultural soil in the Qinghai Tibetan Plateau (QTP) in China.

Bacterial communication intelligently regulates their interactions in anammox consortia under decreasing temperatures.

Bacterial communication could affect their interactions, but whether this regulation has "intelligence" is still unknown. Here, we operated an anammox reactor under temperature gradient from 35 °C to 15 °C. As results, expression abundance of bacterial communication genes increased by 12 % significantly after temperature declined.