Solution-focused brief therapy combined with mindfulness-based stress reduction to alleviate claustrophobia during MR imaging.

Background: This study evaluates the influence of solution-focused approaches combined with mindfulness-based stress reduction (MBSR) on claustrophobia in a high-risk cohort undergoing magnetic resonance (MR) imaging.

Methods: In the prospective observational 2-group study, a total of 77 patients (55% male, mean age 50.1 ± 11.

The influential mechanisms of solution chemistry on the stability and transport of vanadium-titanium magnetite tailing colloids.

Vanadium-titanium magnetite tailing colloids (TCs) from mineral weathering and industrial production can cause overlooked vanadium groundwater pollution due to their mobility and releasable vanadium. This study investigated the stability and transport mechanisms of vanadium-titanium magnetite TCs under various solution chemistries, including pH, ionic strength (IS), acetic acid (AA), oxalic acid (OA), and citric acid (CA), via field survey, batch, and column experiments with numerical modeling. The results showed field-existing evidence of TCs, AA, OA, and CA in the groundwater of the V-Ti magnetite tailing pond.

Dietary manganese intake is positively associated with metabolic dysfunction-associated steatotic liver disease: a multicohort study.

Background And Aims: Manganese (Mn) is an essential nutrient that plays a crucial role in maintaining normal physiological functions of the human body. However, overexposure to Mn often leads to adverse health outcomes and contributes to the development of a variety of diseases. Several studies have explored the relationship between dietary Mn and metabolic dysfunction-associated steatotic liver disease (MASLD) risk.

VPS9D1-AS1 antisense therapy via lipid nanoparticles reprograms cold tumors and enhances immunotherapy in colorectal cancer.

Advanced colorectal cancer (CRC) is characterized by a highly suppressive immune tumor microenvironment (TME) and is insensitive to immunotherapy. The induction of cancer immunogenic cell death (ICD) has been acknowledged as a promising immunotherapeutic strategy. Here, we demonstrate that the long noncoding RNA VPS9D1-AS1 is expressed predominantly in consensus molecular subtype (CMS)-2 CRC, and that its overexpression is associated with immune checkpoint blockade (ICB) sensitivity.

Comprehensive Analysis of the Biomechanical Research of Pelvic Organ Prolapse: A Scientometric Approach.

Background: Pelvic organ prolapse (POP) has become a significant public health issue, with its prevalence increasing proportionally with age. Despite the considerable number of biomechanical studies reported on POP, there remains a lack of a systematic approach to summarize and synthesize all existing research.

Methods: The Web of Science Core Collection (WoSCC) database was used as the data source to select literature published from 2003 to 2023 related to biomechanical research of POP.

The impact of radiation-related lymphocyte recovery on the prognosis of locally advanced esophageal squamous cell carcinoma patients: a retrospective analysis.

Background: The impact of radiation-related lymphocyte recovery on prognosis in locally advanced esophageal squamous cell carcinoma (LA-ESCC) remains unclear.

Methods: Patients with stage II-IVa ESCC who received definitive RT were screened. Collect absolute lymphocyte counts (ALCs) before, during, and after RT.

Association between Daily Sesame Consumption and the Risk of Sarcopenia in Elderly Adults: The Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study.

Background: Sarcopenia is an age-related, progressive, and systemic skeletal muscle disorder that can lead to numerous adverse outcomes. Animal studies have shown that sesame can enhance skeletal muscle blood flow and improve physical performance. However, no studies have yet explored the association between sesame consumption and the incidence of sarcopenia in the general population.

KDELR3 overexpression as a novel prognostic and diagnostic biomarker in glioma: comprehensive bioinformatic analysis insights.

Glioma, the most prevalent primary intracranial malignancy among adults, is distinguished by its high morbidity and recurrence rates, posing a considerable threat to patients' quality of life and survival prospects. Consequently, the pursuit of efficacious molecular prognostic markers holds paramount importance. The exploration of the role of the KDELR3 kinase family in various neoplastic conditions constitutes an emerging area of research.

[Investigation on cognition for insomnia and preference for acupuncture in breast cancer survivors: a in-depth interview study].

Objective: To understand the cognition for insomnia and preference for acupuncture in breast cancer survivors based on the in-depth interview.

Methods: Thirty breast cancer survivors with insomnia symptoms were collected for in-depth interview. The interview questions included three aspects, i.

Sinonasal teratocarcinosarcoma involving the nasal cavity, unilateral paranasal sinuses, and intracranial invasion: A case report.

Background: Sinonasal teratocarcinosarcoma (SNTCS) is a rare and highly invasive neoplasm originating from the nasal cavity and sinuses. Typically, it exhibits an invasive behavior towards adjacent structures; however, in exceptional instances, it may infiltrate the intracranial compartment. Due to the tumor's rarity and lack of distinctive features on computed tomography (CT) and magnetic resonance imaging (MRI) images, SNTCS is often misdiagnosed.

Deep learning for MRI lesion segmentation in rectal cancer.

Rectal cancer (RC) is a globally prevalent malignant tumor, presenting significant challenges in its management and treatment. Currently, magnetic resonance imaging (MRI) offers superior soft tissue contrast and radiation-free effects for RC patients, making it the most widely used and effective detection method. In early screening, radiologists rely on patients' medical radiology characteristics and their extensive clinical experience for diagnosis.

Integrating GEO, network pharmacology, and in vitro assays to explore the pharmacological mechanism of Bruceae Fructus against laryngeal cancer.

The goal of this study is to look into the pharmacological mechanism of Bruceae Fructus in conjunction with GEO, network pharmacology, and in vitro assays for the treatment of laryngeal cancer to provide theoretical support for its therapeutic use. The active components and matching targets of Bruceae Fructus were retrieved from the TCMSP database, while genes linked with laryngeal cancer were obtained from the GEO, GeneCards, DisGeNET, and DrugBank databases. Besides, the components and targets were supplemented by literatures in PubMed database.

Abnormal metabolic connectivity in default mode network of right temporal lobe epilepsy.

Aims: Temporal lobe epilepsy (TLE) is a common neurological disorder associated with the dysfunction of the default mode network (DMN). Metabolic connectivity measured by 18F-fluorodeoxyglucose Positron Emission Computed Tomography (18F-FDG PET) has been widely used to assess cumulative energy consumption and provide valuable insights into the pathophysiology of TLE. However, the metabolic connectivity mechanism of DMN in TLE is far from fully elucidated.

Spatial and Temporal Distribution and the Driving Factors of Carbon Emissions from Urban Production Energy Consumption.

Urban production energy consumption produces a large amount of carbon emissions, which is an important source of global warming. This study measures the quantity and intensity of carbon emissions in 30 provinces of China based on urban production energy consumption from 2005-2019, and uses the Dagum Gini coefficient, kernel density estimation, carbon emission classification and spatial econometric model to analyze the spatial and temporal distribution and driving factors of quantity and intensity of carbon emissions from China and regional production energy consumption. It was found that the growth rate of carbon emission quantity and carbon emission intensity of production energy consumption decreased year by year in each province during the study period.

Cocrystallization tailoring radiative decay pathways for thermally activated delayed fluorescence and room-temperature phosphorescence emission.

Modulation of excited-state processes in binary organic cocrystals has been rarely explored so far. Here, we develop two charge-transfer (CT) cocrystal microrods with a 1 : 1 stoichiometric ratio where halogenated dibenzothiophene (DBT) compounds act as π-electron donors and 1,2,4,5-tetracyanobenzene (TCNB) acts as an acceptor. Unexpectedly, the cocrystal containing one bromine (Br) atom at the 3-position of DBT (3-BrTC) presents thermally activated delayed fluorescence (TADF), while the other one comprising one Br atom at the 4-position of DBT (4-BrTC) exhibits both TADF and room-temperature phosphorescence (RTP).

The Added Value of Combined Timed Up and Go Test, Walking Speed, and Grip Strength on Predicting Recurrent Falls in Chinese Community-dwelling Elderly.

Purpose: To determine whether combined performance-based models could exert better predictive values toward discriminating community-dwelling elderly with high risk of any-falls or recurrent-falls.

Participants And Methods: This prospective cohort study included a total of 875 elderly participants (mean age: 67.10±5.

Regulation of Thermally Activated Delayed Fluorescence to Room-Temperature Phosphorescent Emission Channels by Controlling the Excited-States Dynamics via J- and H-Aggregation.

Control of excited-state dynamics is key in tuning room-temperature phosphorescence (RTP) and thermally activated delayed fluorescence (TADF) emissions but is challenging for organic luminescent materials (OLMs). We show the regulation of TADF and RTP emissions of a boron difluoride β-acetylnaphthalene chelate (βCBF ) by controlling the excited-state dynamics via its J- and H-aggregation states. Two crystalline polymorphs emitting green and red light have been controllably obtained.

High-Lying 3A Dark-State-Mediated Singlet Fission.

Singlet fission (SF), the conversion of one high-energy singlet to two low-energy triplets, provides the potential to increase the efficiency of photovoltaic devices. In the SF chromophores with symmetry, exemplified by polyenes, singlet-to-triplet conversion generally involves a low-lying 2A dark state, which serves as either a multiexciton (ME) intermediate to promote the SF process or a parasitic trap state to shunt excited-state populations via internal conversion. This controversial behavior calls for a deep understanding of dark-state-related photophysics involving the higher-lying singlet state.

Tunable Triplet-Mediated Multicolor Lasing from Nondoped Organic TADF Microcrystals.

Thermally activated delayed fluorescent (TADF) emitters have received great attention in organic light-emitting diodes and laser diodes because of high exciton utilization efficiency and low optical loss caused by triplets. However, the direct observation of lasing emission from nondoped TADF microcrystals has yet to be reported. Here, we demonstrated a three-color (green, yellow, and red) microlaser from three nondoped TADF microcrystals with well-controlled geometries.

DNA repair enzyme OGG1 promotes alveolar progenitor cell renewal and relieves PM2.5-induced lung injury and fibrosis.

Fine particulate matter (PM2.5) airborne pollution increases the risk of chronic respiratory diseases, such as idiopathic pulmonary fibrosis (IPF), which is characterized by non-specific inflammation of the interstitial lung and extensive deposition of collagen fibers. Type 2 alveolar epithelial cells (AEC2s) are alveolar stem cells in the adult lung that contribute to the lung repair process through complex signaling.

Breaking Kasha's Rule as a Mechanism for Solution-Phase Room-Temperature Phosphorescence from High-Lying Triplet Excited State.

Organic room-temperature phosphorescence (ORTP) has been demonstrated successfully in solids. In contrast, solution-phase ORTP is rarely achieved, because the T → S phosphorescence is too slow to compete against nonradiative decay and the oxygen-quenching effect. Here, we reported that suppression of Kasha's rule is a strategy to achieve solution-phase ORTP from the high-lying T state by spatially separating T and T on different parts of the molecule (CzCbDBT) composed of carbonyl (Cb), dibenzothiophene (DBT), and carbazole moiety (Cz).

[Effect of Schizonepetae Herba and Saposhnikoviae Radix on expression of AQP4 and AQP8 in colonic mucosa of rats with ulcerative colitis].

The aim of this paper was to investigate the effect of Schizonepetae Herba and Saposhnikoviae Radix(wind medicine) on the expression of AQP4 and AQP8 in colonic mucosa in rats with ulcerative colitis(UC). A total of 35 healthy SD male rats were randomly divided into normal group(gavaged with normal saline), DSS model group, as well as low, middle, and high dose wind medicine groups(Schizonepeta and Saposhnikovia 1∶1, gavaged at dosages of 6, 12, and 24 g·kg~(-1)·d~(-1)), with 7 in each group. UC rat model was established by free drinking of 3% dextran sulphate sodium(DSS) solution for 10 days.

Effects of different living conditions on the risk of osteoporosis in Chinese community-dwelling elderly: a 3-year cohort study.

Objective: Osteoporosis can lead to bone fragility and an increased risk of bone fracture with resultant high morbidity and mortality. Living alone has been associated with various mental and physical health problems. However, the risk of osteoporosis among individuals with different living conditions and changing living conditions is unclear.

Combined Depression and Malnutrition As an Effective Predictor of First Fall Onset in a Chinese Community-Dwelling Population: A 2-Year Prospective Cohort Study.

This study aims to explore the single and joint effects of depression and malnutrition on the incidence of first fall onset in a Chinese community-dwelling elderly population. This cohort study consisted of 739 residents without a history of falls who were aged 60 years and older (mean age: 67.08 ± 5.