Optimized Multi-Antenna MRC for 16-QAM Transmission in a Photonics-Aided Millimeter-Wave System.

This work presents an 80 Gbps photonics-aided millimeter-wave (mm Wave) wireless communication system employing 16-Quadrature Amplitude Modulation (16-QAM) and a 1 × 2 single-input multiple-output (SIMO) architecture with maximum ratio combining (MRC) to achieve robust 87.5 GHz transmission over 4.6 km.

Laparoscopic Bladder Neck Wedge Resection with Preservation of the Posterior Urethral Bed Versus Transurethral Resection of the Bladder Neck for Refractory Bladder Neck Contracture: A Comparative Study.

Background And Objective: Refractory bladder neck contracture (BNC) poses significant challenges after transurethral resection of the prostate. This study compares laparoscopic bladder neck wedge resection with posterior urethral bed preservation (LCBNRE) versus transurethral resection of the bladder neck (TURBN) in managing refractory BNC.

Methods: A retrospective analysis was conducted of 103 patients (2018-2023) divided into the LCBNRE ( = 58) and TURBN ( = 45) groups.

Research on Tbps and Kilometer-Range Transmission of Terahertz Signals.

THz communication stands as a pivotal technology for 6G networks, designed to address the critical challenge of data demands surpassing current microwave and millimeter-wave (mmWave) capabilities. However, realizing Tbps and kilometer-range transmission confronts the "dual attenuation dilemma" comprising severe free-space path loss (FSPL) (>120 dB/km) and atmospheric absorption. This review comprehensively summarizes our group's advancements in overcoming fundamental challenges of long-distance THz communication.

Influences of Ar Flow-Rate and Sublimation Temperature on the Sublimation Product of Analytical Reagent MoO.

In this work, the influences of the Ar flow-rate and sublimation temperature on the phase composition and morphological structure of the sublimation products of analytical reagent MoO are investigated. The results show that the sublimation products are always composed of thermodynamically stable orthorhombic molybdenum trioxide (α-MoO) and metastable monoclinic molybdenum trioxide (β-MoO) under different reaction conditions, among which the proportion of β-MoO gradually increases with the increase in Ar flow-rate and the decrease in sublimation temperature. The formation temperature of α-MoO is mainly between 780 K and 847 K, with the particles exhibiting an obvious sheet-like morphology.

Low-noise frequency synthesis and terahertz wireless communication driven by compact turnkey Kerr combs.

High frequency microwave, spanning up to terahertz frequency, is pivotal for next-generation communication, sensing and radar. However, it faces fundamental noise limitations when frequency is pushed towards such boundary of conventional electronic technologies. Photonic microwave generation, particularly Kerr-comb-based microwave source, benefits from high frequency operation but still suffers from phase noise constraints.

120 Gbit/s PDM-16QAM terahertz signal over 850 m using 2 × 2 MIMO links and advanced DSPs.

The wireless range and data capacity of photonics terahertz (THz) communication systems above 300 GHz are limited by outdoor environmental challenges, including high atmospheric attenuation, water absorption, and efficiency limitations of optical-to-electrical conversion. In this Letter, we have showcased a dual-channel 2 × 2 multiple-input multiple-output (MIMO) system achieving a record 120 Gbit/s polarization-division multiplexing 16-ary quadrature amplitude modulation (PDM-16QAM) signal delivery over a wireless distance of 850 m at 300 GHz based on polarization multiplexing and advanced digital signal processing (DSP) technology. This demonstrates the largest (R-D) product of 88,655 Gbit/s*m globally.

SMYD3 as an Epigenetic Regulator of Renal Tubular Cell Survival and Regeneration Following Acute Kidney Injury in Mice.

The protein SET and MYND-Domain Containing 3 (SMYD3) is a methyltransferase that modifies various non-histone and histone proteins, linking it to tumorigenesis and cyst formation. However, its role in acute kidney injury (AKI) remains unclear. This study investigates the role and mechanism of AKI using a murine model of ischemia-reperfusion (IR)-induced AKI.

High-resolution dynamically downscaled projections of future extreme temperatures, heatwaves and exposure in Southeast Asia.

Extreme heat and heatwaves driven by global warming pose escalating risks globally, particularly in Southeast Asia (SEA), home to 680 million people, with a high concentration in urban areas. This study made use of CMIP6-based convection-permitting dynamically downscaled simulations at 8 km resolution over SEA under the three Shared Socioeconomic Pathways (SSP) scenarios: SSP1-2.6, SSP2-4.

Digital Frequency-Domain MIMO Equalizer Enabling Six-LP-Mode Strong-Coupling IM/DD MDM Optical Transmission System.

Mode division multiplexing (MDM) techniques provide significant enhancement of the capacity of optical intensity modulation and direct detection (IM/DD) short-reach communication systems, like the datacenter interconnection scenarios. While the introduction of multiple modes leads to mode coupling that will extremely deteriorate the received signals, two approaches have been explored to address this issue: one involves the application of all-link weakly coupled components to suppress modal crosstalk, while the other utilizes optical multiple-input-multiple-output (MIMO) equalizers based on optical devices for signal decoupling. However, pure digital signal processing (DSP)-based schemes for mode decoupling in IM/DD MDM systems with strong mode coupling remain unexplored.

2024 International Expert Consensus on US-guided Thermal Ablation for T1N0M0 Papillary Thyroid Cancer.

Thermal ablation has started to gain acceptance as a therapeutic approach for the management of papillary thyroid cancer (PTC), mainly in the T1 stage (tumor size ≤ 2 cm in greatest dimension and limited to the thyroid). Despite its increasing popularity, a lack of uniformity in the technical details persists, and existing guidelines do not fully align with recent research advancements. To standardize the use of US-guided thermal ablation for T1N0M0 PTC, a panel of experts jointly issued this expert consensus on thermal ablation for PTC.

A Hybrid RF/FSO Transmission System Based on a Shared Transmitter.

In this work, we propose a novel design of a hybrid transmission integrated system for radio frequency (RF) and free-space optical (FSO) communications, in which the RF and FSO links are able to share the transmitter and the transmission link. In this system, the RF link can usually be considered as a complement to the FSO link, and the hybridization of the two transmissions allows the system to adapt to a variety of complex environments while maintaining a high rate of transmission, improves system stability, and greatly reduces system complexity through the design of a shared transmitter. An experimental demonstration of the system has been carried out, and the results show that the hybrid RF/FSO system supports 50 Gbit/s transmission, satisfying the 20% soft-decision forward error correction (SD-FEC) threshold of 2.

A case report of urethral corpus cavernosum pseudoaneurysm formation after ultrasound-guided transperineal prostate biopsy.

Background: Prostate biopsy is a critical procedure for diagnosing prostate cancer, with severe complications being relatively uncommon. This report presents a complex case of an elderly patient who developed urethral cavernous pseudoaneurysm, persistent bleeding, and disseminated intravascular coagulation (DIC) following ultrasound-guided transperineal prostate biopsy. The patient was managed through timely diagnosis and intervention by a multidisciplinary team, ultimately achieving bleeding control and clinical stabilization.

New insights into the transcription factor regulatory networks driving peel coloration under hormone induction analyzed by transcriptomics and metabolomics in tangor 'Murcot'.

Introduction: Fruit color is a crucial quality factor strongly influencing consumer preference for citrus. The coloration of citrus fruit is primarily determined by carotenoids, which produce a range of hues. Gibberellic acid (GA) and ethylene are critical in fruit coloration during the ripening process.

Efficacy and safety of ongericimab in Chinese patients with heterozygous familial hypercholesterolemia: A randomized, double-blind, placebo-controlled phase 3 trial.

Background And Aims: Heterozygous familial hypercholesterolemia (HeFH) is a prevalent autosomal dominant disorder of lipid metabolism but severely underdiagnosed and undertreated in China. This phase 3 trial aims to evaluate the efficacy and safety of ongericimab, a novel monoclonal antibody that targets proprotein convertase subtilisin/kexin type 9 (PCSK9), in Chinese patients with HeFH.

Methods: Patients who have been diagnosed with definite HeFH according to Dutch Lipid Clinical Network criteria and receiving stable and optimized lipid-lowering therapy were enrolled.

Unveiling Ultrafast Vibration Detection from Nanostructures: Cluster Arrays Achieving Precise Responses without Direct Interparticle Mechanical Interaction.

Sensitive materials assembled with nanostructures respond to subjected mechanical stimuli by modulating the internal electron transport through their intrinsic deformation. However, this deformation inherently entails a sufficient delay to overcome mechanical interactions between nanostructures to propagate within materials, thereby limiting the timely responsiveness of sensitive materials to ultrafast mechanical stimuli. Here, we propose a novel sensing array composed of isolated clusters, where majority of the clusters maintain nanoscale separations from each other.

CPT1A mediates succinylation of LDHA at K318 site promoteing metabolic reprogramming in NK/T-cell lymphoma nasal type.

Carnitine palmitoyltransferase 1A (CPT1A), a succinylating enzyme, is highly expressed in various malignant tumors and promotes tumor progression. Succinylation is a posttranslational modification that has been reported in various diseases, but its role in NK/T-Cell lymphoma nasal type (ENKTL-NT) remains underexplored. In this study, bioinformatics analysis showed that glycolytic is a major metabolic pathway in ENKTL-NT as the expression of many glycolytic related kinases are increased.

Calcium/calmodulin-dependent protein kinase II α and β differentially regulate mammalian sleep.

While sleep is important, our understanding of its molecular mechanisms is limited. Over the last two decades, protein kinases including Ca/calmodulin-dependent protein kinase II (CaMKII) α and β have been implicated in sleep regulation. Of all the known mouse genetic mutants, the biggest changes in sleep is reported to be observed in adult mice with sgRNAs for Camk2b injected into their embryos: sleep is reduced by approximately 120 min (mins) over 24 h (hrs).

Calcineurin: An essential regulator of sleep revealed by biochemical, chemical biological, and genetic approaches.

Research into mechanisms underlying sleep traditionally relies on electrophysiology and genetics. Because sleep can only be measured on whole animals by behavioral observations and physical means, no sleep research was initiated by biochemical and chemical biological approaches. We used phosphorylation sites of kinases important for sleep as targets for biochemical and chemical biological approaches.

Low-cost 100 G PON based on a residual optical carrier for carrier recovery.

We experimentally demonstrate a cost-effective dual-polarization quadrature phase shift keying (DP-QPSK) coherent passive optical network (PON) system that operates at 100 Gbits/s/λ. This system utilizes distributed feedback lasers (DFBs) and a carrier recovery algorithm facilitated by a bifunctional frequency-domain pilot tone (FPT). To reduce costs in coherent PON implementations, low-cost DFBs are employed as the sole light sources, replacing the more expensive external cavity lasers (ECLs) at both the optical line terminal (OLT) and the optical network units (ONUs).

New Design Scheme for and Application of Fresnel Lens for Broadband Photonics Terahertz Communication.

In terahertz communication systems, lens antennas used in transceivers are basically plano-convex dielectric lenses. The size of a plano-convex lens increases as the aperture increases, and thinner lenses have longer focal lengths. Through theory and simulation, we designed a Fresnel lens suitable for the terahertz band to meet the requirements of large aperture and short focal length, and simulated the performance, advantages, and disadvantages of the terahertz Fresnel lens.

One-shot pre-equalization scheme based on frequency pilot tones for bandwidth-limited IM/DD DCI transmission.

O-band intensity modulation and direct detection (IM/DD) transmission offers a promising solution for high-speed data center interconnects (DCIs). Additionally, the introduction of bismuth-doped fiber amplifiers (BDFAs) results in less nonlinear impact and a higher link budget compared with semiconductor optical amplifiers (SOAs). However, with these key issues resolved, the system bandwidth limitation emerges as the next critical bottleneck for high-speed O-band DCI transmission that limits overall performance.

Kalman filtering-based decision threshold dynamic optimization in photonics-aided millimeter-wave systems.

We propose a novel, to the best of our knowledge, decision threshold dynamic optimization (DTDO) method based on Kalman filtering to mitigate the nonlinear effect impacts of the time-domain jitter and saturation distortion on a bit error rate (BER) performance. This dynamic optimization method was validated in a photonics-aided W-band millimeter-wave system. Compared to nonlinear algorithms and clustering classification methods, DTDO offers lower complexity and superior dynamic tracking capabilities when optimizing the BER performance in photonics-aided systems.