Seismic random noise separation and suppression based on improved variational mode decomposition via grey wolf optimization.

Seismic noise separation and suppression is an important topic in seismic signal processing to improve the quality of seismic data recorded at monitoring stations. We propose a novel seismic random noise suppression method based on enhanced variational mode decomposition (VMD) with grey wolf optimization (GWO) algorithm, which applies the envelope entropy to evaluate the wolf individual fitness, determine the grey wolf hierarchy, and obtain the optimized key elements K and α in VMD. Then, the decomposed effective intrinsic mode functions (IMFs) are extracted to separate and suppress random noises.

Vellus Hair-Inspired Triboelectric Antenna for Approach and Pressure Sensing.

Mimicking the human sensory function of hair tissue for robotic tactile and noncontact perception is significant but remains challenging. In this work, we designed a triboelectric artificial antenna (TAA) with controllable mechanical properties inspired by the structure of human hair to achieve proximity perception and detection of weak pressure. External forces or charged objects can disturb the original spatial electric field generated by space charges in the polymer fibers, leading to changes in the potentials on the electrodes of the triboelectric device.

PN-CeO as a potential therapeutic agent for atopic dermatitis: Antioxidant and anti-inflammatory effects.

Atopic dermatitis (AD) is a common inflammatory skin disorder, and oxidative stress plays a central role in its pathogenesis. Nanoceria, owing to its redox-regulating properties, hold promise as a treatment option for AD. Porous ceria nanorods (PN-CeO) were synthesized to scavenge reactive oxygen species (ROS).

Ball-milling-mediated remote asymmetric reductive coupling in air.

Dicarbofunctionalization reactions of unsaturated systems radical relay strategies are crucial for the efficient synthesis of complex molecules. Mechanochemical synthesis offers a compelling alternative to traditional solvent-based methods, providing advantages such as straightforward operation, shorter reaction times, minimal solvent use, and simplified workup. Although racemic two- and three-component solid-state cross-coupling reactions have seen significant advancements, the development of their catalytic asymmetric counterparts remains notably limited.

Nano-curcumin attenuates tamoxifen resistance and malignant progression in ER-positive breast cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway.

Breast cancer (BC) is one of the most prevalent malignant tumors among women, with estrogen receptor (ER)-positive patients constituting approximately 70 % of all cases. Endocrine therapy is currently a treatment option for patients with ER-positive BC; however, the development of resistance significantly limits the effectiveness of this treatment. Nano-curcumin (Nano-CUR) possesses anticancer properties and enhances bioavailability by improving the hydrophobic character of curcumin (CUR).

Pulmonary mesenchymal cystic hamartoma with EWSR1::CREM fusion: molecular redefinition and diagnostic implications.

Pulmonary mesenchymal cystic hamartoma (MCH) is an exceptionally rare benign tumor characterized by cystic-solid architecture and biphasic epithelial-mesenchymal components. We report a 56-year-old woman with a 2.6-cm right lower lobe mass, histologically composed of pseudostratified ciliated epithelium, glandular components, and primitive mesenchymal cells with cartilaginous/adipose differentiation.

Exploring the impact of coffee consumption and caffeine intake on cognitive performance in older adults: a comprehensive analysis using NHANES data and gene correlation analysis.

Purpose: To investigate the effects of coffee consumption and caffeine intake on cognitive performance in older adults, with a particular focus on the potential mediating role of alkaline phosphatase(ALP).

Methods: We analyzed data from the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2014, involving 2,254 participants aged 60 and older. Cognitive performance was assessed using the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) test, Animal Fluency test, and Digit Symbol Substitution Test (DSST).

Switching between type I/II photosensitization processes for of an unconventional dye as modulated by the tumor microenvironment for inducing immunogenic death.

In this work, an unconventional Se-substituted hemicyanine dye (HCySe-O-NO) decorated with a -nitrophenyl moiety as a recognition site was investigated. Its type I/II photosensitization processes could be regulated by the tumor microenvironment, alleviating the oxygen dependence of conventional photodynamic therapy (PDT) for the treatment of solid tumors. Upon being exposed to 760-nm-wavelength laser irradiation, cancer cells treated with HCySe-O-NO exhibited the phenomenon of pyroptosis, resulting in an amplification of cellular immunogenic death (ICD), and hence demonstrating the potential value of this dye for photoimmunotherapy.

Predictive value of preoperative L3-SMI, AGR, and PNI for overall survival in patients undergoing radical gastrectomy for gastric cancer.

Objectives: Gastric cancer (GC) is the fifth most common cancer and the third leading cause of cancer-related death worldwide, posing a serious threat to public health. Prognostication of overall survival (OS) in patients undergoing radical gastrectomy remains a clinical priority. Evidence suggests that preoperative nutritional and inflammatory status correlated with postoperative outcomes.

HMGB1/RAGE signaling mediates the activation of microglia and participates in depressive-like behaviors and cognitive deficits in rats after ischemia-reperfusion.

Post-stroke depression (PSD) is a common psychiatric complication that occurs after stroke, especially in ischemic stroke (I/S). It has been reported that high-mobility group box-1 (HMGB1) is highly expressed in clinical PSD patients, but the exact molecular mechanism of its involvement in PSD is not completely clear, the neuroinflammation may participate in its development. Thus, we established a PSD rat model, observed behavioral and cognitive deficits, and found that the HMGB1/ receptor for advanced glycation end products (RAGE) pathway were activated in microglia.

Landscapes of gut microbiome and metabolic signatures in vitiligo patients with co-morbid emotional distress.

Background: Vitiligo is a depigmentation disorder frequently associated with emotional distress; however, the precise mechanisms underlying this co-morbidity remain unclear.

Objective: This study aims to investigate whether gut dysbiosis and gut metabolites contributes to emotional distress in patients with vitiligo.

Methods: Depression and anxiety were assessed using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7, respectively.

Targeting PSMD14 combined with arachidonic acid induces synthetic lethality via FADS1 mA modification in triple-negative breast cancer.

Dysregulation of deubiquitination is essential for cancer growth. However, the role of 26 proteasome non-ATPase regulatory subunit 14 (PSMD14) in the progression of triple-negative breast cancer (TNBC) remains to be determined. Gain- and loss-of-function experiments showed that silencing PSMD14 notably attenuated the growth, invasion, and metastasis of TNBC cells in vitro and in vivo.

A Hierarchical Contact-Electrification Interface Based on Gradient Micro-/Nanostructured Hydrogel for Cardiovascular Disease Monitoring.

Accurate monitoring of pulses is essential for assessing cardiovascular health. However, the specificity of the pulse wave depends on prestress applied to a wearable sensor. Here, we introduce a progressive contact area compensation strategy, which greatly extends the detection range of the sensor's high-sensitivity region.

Neural correlates of risk decision-making: Insights from the balloon analogue risk task and exponential-weight mean-variance model.

Risk decision-making involves complex cognitive processes, posing challenges in cognitive neuroscience. This study used the Exponential-Weight Mean-Variance (EWMV) model and intersubject representational similarity analysis (ISRSA) to examine the neural mechanisms of five key processes-prior belief, learning rate, risk preference, loss aversion, and behavioral consistency-during the Balloon Analogue Risk Task (BART). We identified distinct and overlapping neural substrates across three BART stages.

Resource recovery from iodine-containing silver-loaded silica gel: Recycling of silver and immobilization of iodine.

Silver-loaded silica gel is widely used in spent fuel reprocessing plant due to its high adsorption efficiency of iodine and low influence of humidity and NO. This study proposed a novel method for the disposal of iodine-loaded silver-silica gel. The elution of iodine using NaS solution, the leaching of silver through HNO solution.

Overexpression of S100B promotes depressive-like behaviors in stroke-induced rats by modulating the PI3K/AKT/NF-κB pathway.

Post-stroke depression (PSD) is a common complication following a stroke, primarily characterized by low mood, cognitive sluggishness, and sleep disturbances. Currently, the precise pathogenic mechanisms underlying PSD remain elusive. Research indicates that S100B protein levels may serve as a specific biochemical marker of organic brain injury, with significantly elevated serum S100B levels noted in patients with ischemic stroke, depression, and schizophrenia.

Polyneuritis cranialis combined with Horner's syndrome: a rare variant of Guillain Barré syndrome.

Background: Polyneuritis cranialis (PNC), a rare variant of Guillain-Barré syndrome (GBS), is usually characterized by ocular and pharyngeal weakness without obvious numbness or weakness of the limbs or ataxia. Horner's syndrome is extremely rare in patients with PNC. Here, we describe a case of GBS presenting with acute PNC and unilateral Horner syndrome.

Predicting Benign and Malignant Subpleural Pulmonary Lesions With a Nomogram Model Using Clinical and B-Mode Ultrasound Parameters.

Objective: To develop and validate an individualized nomogram for distinguishing between benign and malignant subpleural pulmonary lesions (SPLs) using B-mode ultrasound imaging and clinical data.

Methods: A total of 425 patients with SPLs were enrolled and classified into two groups: 220 patients were diagnosed with malignant lesions, and 205 with benign lesions. Patients were randomly assigned to a development cohort (DC, n = 297) and a validation cohort (VC, n = 128) in a 7:3 ratio.

Probiotics and muscle health: the impact of on sarcopenia through the gut-muscle axis.

Sarcopenia refers to the decline in skeletal muscle mass and function. Due to its increased mortality rate and severe disability, the clinical importance of sarcopenia is becoming increasingly prominent. Although the exact cause of sarcopenia is not fully understood, the gut microbiota (GM) plays a crucial role in the pathogenesis of sarcopenia, and increasing evidence suggests that gut dysbiosis may be associated with disease development.

A DMSO-modified porous organogel with breathability and degradability for wearable electronics.

Wearable electronics for real-time monitoring of the physical status of the human body have been significantly developed recently. However, the substrates of wearable electronics still suffer from the challenge, including weak mechanical properties, low breathability and weak degradation capabilities. Herein, a dimethyl sulfoxide (DMSO)-modified agar organogel (DSAO) with porous microstructures has been reported as a breathable and degradable substrate for wearable electronics.

EIS Study on Competitive Adsorption at the TiO-Solution Interface.

Understanding the competition and configuration of ionic adsorption on the electrode surface is crucial for electrocatalytic reactions and corrosion science. Here, we demonstrate how EIS can be employed to identify the competitive adsorption of phosphate and chloride ions on the surface of a Ti/TiO electrode in a complex solution system. By controlling the concentration of phosphate ions in a high-concentration chloride ion (100 mM) and different pH (5.

Ground-state charge transfer in single-molecule junctions covalent organic frameworks for boosting photocatalytic hydrogen evolution.

Ground-state charge transfer plays a vital role in improving the photocatalytic performance of D-A type covalent organic frameworks. However, limited studies have explored the modulation of photocatalytic performance in COFs-based photocatalysts through ground-state charge transfer. Here we show the formation of extremely intense ground-state charge transfer via a unique covalent bonding approach.

Rapid aging of influenza epidemics in China from 2005/06 to 2016/17: A population-based study.

Background: China is an aging society, and the older population is at a higher risk of influenza infection and influenza-related mortality. However, there is limited knowledge regarding the aging of influenza epidemics, which is crucial for estimating the disease burden.

Methods: We collected weekly influenza surveillance data from 2005/06 to 2016/17, and quantified the aging of influenza-like illness (ILI) and influenza virus-positive cases in China via the mean age of the influenza cases and the proportion of individuals aged 65 and above among the influenza cases.