On-Demand Ammonia Capture and Separation with Open Aluminophosphate Frameworks.

The development of adsorbents for ammonia capture and separation is a challenging task, with significant industrial relevance. We report herein, for the first time, open aluminophosphate frameworks for on-demand ammonia adsorption. Under ambient conditions, the AlPO-18 molecular sieve exhibits exceptional dynamic ammonia uptake of 3.

Spikey biodegradable MXene nanosheets with enhanced cellular internalization and stimuli-responsive drug delivery for synergistic cancer therapy.

Unlabelled: Two-dimensional (2D) MXenes are promising theranostic nanoplatforms, but their limited drug-loading capacity and intracellular delivery hinder therapeutic efficacy. Here, we develop a spikey MXene (sMXene) nanosheet via a self-assembly strategy that enables the controlled growth of porous SiO on the MXene surface. Bis [3-(triethoxysilyl) propyl] tetrasulfide was also introduced into the reaction system to achieve the degradation of spikey MXene (dsMXene).

Extraction, content determination, component analysis, and pharmacological action of Hedysari flavonoids: a review of research progress.

Radix Hedysari is a traditional Chinese herbal medicine and food. It has a long history of clinical application and is used to improve health and treat various diseases. Hedysari polysaccharides, flavonoids, saponins, and alkaloids are the main components of Radix Hedysari.

Optimal dietary vitamin B1 content enhanced egg production, eggshell thickness, and serum antioxidant status in breeder geese.

Objective: This study aimed to evaluate the effects of vitamin B1 (VB1) supplementation on laying performance, egg quality, serum biochemical parameters, antioxidant status, and nutrient digestion in breeder geese.

Methods: A total of 150 geese (30 males and 120 females, aged 34 weeks) were randomly assigned to 6 dietary treatment groups, each 5 replicates of 5 birds (1 male and 4 females). The geese were fed a basal diet supplemented with 0 (control), 1, 2, 3, 4, or 5 mg/kg of VB1 for 10 weeks.

Density Functional Theory Insights into Conduction Mechanisms in Perovskite-Type RCoO Nanofibers for Future Resistive Random-Access Memory Applications.

In the era of artificial intelligence and Internet of Things, data storage has an important impact on the future development direction of data analysis. Resistive random-access memory (RRAM) devices are the research hotspot in the era of artificial intelligence and Internet of Things. Perovskite-type rare-earth metal oxides are common functional materials and considered promising candidates for RRAM devices because their interesting electronic properties depend on the interaction between oxygen ions, transition metals, and rare-earth metals.

LaF@SiO yolk-shell heterostructure nanofiber-modified separator enhances the long-cycling performance of lithium-sulfur batteries.

High-energy-density lithium-sulfur (Li-S) cells are identified as one of the most prospective next-generation energy storage appliances owing to their numerous advantages. Nonetheless, their widespread applications are restricted by the unwanted shuttling effect and tardy conversion reaction kinetics of lithium polysulfides (LiPSs). To address these puzzles, we present an innovative strategy for the one-pot synthesis of LaF@SiO yolk-shell heterostructure nanofibers (YSHNFs) through a straightforward uniaxial electrospinning process coupled with fluorination, avoiding the complexities of traditional methods.

WTAP increases BMP2 expression to promote osteoblast differentiation and inhibit osteoblast senescence via mA methylation of Sp1.

Pro-differentiation and anti-senescence treatment may be potential strategies for senile osteoporosis therapy. However, the regulatory mechanism underlying osteoblast differentiation and senescence in senile osteoporosis remain to be clarified. In the present study, the preosteoblast cell line MC3T3-E1 was used to induce osteoblast differentiation.

Molecular Trapdoor in HEU Zeolite Enables Inverse CO-CH Separation.

The adsorptive separation of molecules with very similar physical properties is always a challenging task. Reported herein is the design and tailoring of zeolite adsorbent for the precise discrimination and separation of CO-CH mixture through the pronounced trapdoor effect. Typically, Sr exchanged K-type clinoptilolite, namely Sr/K-HEU, is developed as a robust zeolite adsorbent for inverse CO-CH separation, showing the-state-of-the-art dynamic CO/CH selectivity of 48.

Recent advances in two-dimensional materials for drug delivery.

Two-dimensional (2D) materials exhibit significant potential in biomedical applications, particularly as drug carriers. Thus, 2D materials, including graphene, black phosphorus, transition metal dichalcogenides, transition metal carbides/nitrides, and hexagonal boron nitride, have been extensively studied. Their large specific surface area, abundant surface active sites, and excellent biocompatibility and biodegradability make them ideal platforms for drug loading and delivery.

Confined Cu Single Sites in ZSM-5 for Photocatalytic Hydroxylation of Benzene to Phenol.

Zeolites with band-like charge transport properties have exhibited their potential activities in sensing, optics, and electronics. Herein, a precisely designed Cu@ZSM-5 catalyst is presented with an ultra-wide bandgap of 4.27 eV, showing excellent photocatalytic activity in hydroxylation of benzene with benzene conversion 27.

Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth.

Bone metastasis is a lethal consequence of breast cancer. Here we used single-cell transcriptomics to investigate the molecular mechanisms underlying bone metastasis colonization-the rate-limiting step in the metastatic cascade. We identified that lymphotoxin-β (LTβ) is highly expressed in tumour cells within the bone microenvironment and this expression is associated with poor bone metastasis-free survival.

Unraveling molecular aberrations and pioneering therapeutic strategies in osteosarcoma.

Osteosarcoma, a rare primary bone cancer, presents diverse molecular aberrations that underscore its complexity. Despite the persistent endeavors by researchers, the limited amelioration in the five-year survival rate indicates that current therapeutic strategies prove inadequate in addressing the clinical necessities. Advancements in molecular profiling have facilitated an enhanced comprehension of the biology of osteosarcoma, offering a promising outlook for treatment.

Direct and stable hydrogenation of CO to aromatics over a tandem catalyst ZnTiO/HZSM-5.

Direct and stable conversion of CO to aromatics (CTA) is an attractive route for reducing CO emissions. However, due to the chemical inertness of CO, direct CTA reaction with high aromatics selectivity is still challenging. In this work, a tandem catalyst ZnTiO/HZSM-5 with appropriate density and strength of acid sites exhibits a high aromatics selectivity of 67.

Stabilization of Ni-containing Keggin-type polyoxometalates with variable oxidation states as novel catalysts for electrochemical water oxidation.

The development of new recyclable and inexpensive electrochemically active species for water oxidation catalysis is the most crucial step for future utilization of renewables. Particularly, transition metal complexes containing internal multiple, cooperative metal centers to couple with redox catalysts in the inorganic Keggin-type polyoxometalate (POM) framework at high potential or under extreme pH conditions would be promising candidates. However, most reported Ni-containing POMs have been highly unstable towards hydrolytic decomposition, which precludes them from application as water oxidation catalysts (WOCs).

Applying dynamic contrast-enhanced MRI tracer kinetic models to differentiate benign and malignant soft tissue tumors.

Background: To explore the potential of different quantitative dynamic contrast-enhanced (qDCE)-MRI tracer kinetic (TK) models and qDCE parameters in discriminating benign from malignant soft tissue tumors (STTs).

Methods: This research included 92 patients (41females, 51 males; age range 16-86 years, mean age 51.24 years) with STTs.

CeO/Co heterostructure encapsulated in hollow necklace-like carbon fiber as an advanced host material for high-performance lithium-sulfur batteries.

The shuttle effect of lithium polysulfides (LiPSs) and the sluggish reaction kinetics of LiPSs conversion pose serious challenges to the commercial feasibility of lithium-sulfur (Li-S) batteries. To address these obstacles, herein, we construct CeO/Co heterostructures in hollow necklace-like carbon fibers (CeO/Co-CNFs) as the cathode host material for Li-S batteries. The specific surface area of fibers is significantly enhanced by using a template, thereby promoting the utilization efficiency of sulfur.

Novel green/red oxyfluoride phosphors with excellent optical properties for near-UV excited white light emitting diode.

Novel eye-sensitive BaNbOF(HO):Tb green and BaNbOF(HO):Mn red oxyfluoride phosphors with extremely strong absorption in the UV region were designed and synthesized by simple co-precipitation strategy. Particularly, Tb ions were doped in this matrix for the first time, which greatly improves their absorption efficiency in the near ultraviolet region (367 nm) and emits sharp green light (544 nm). In addition, the BaNbOF(HO):Mn red phosphors have strong zero phonon line (ZPL) emission at 625 nm, which is conducive to improving the sensitivity of human eye and color purity.

Large-scale array for radio astronomy on the farside (LARAF).

At the Royal Society meeting in 2023, we have mainly presented our lunar orbit array concept called DSL, and also briefly introduced a concept of a lunar surface array, LARAF. As the DSL concept had been presented before, in this article, we introduce the LARAF. We propose to build an array in the far side of the Moon, with a master station which handles the data collection and processing, and 20 stations with maximum baseline of 10 km.

Control of Zeolite Local Polarity toward Efficient Xenon/Krypton Separation.

The inherent inertness and striking physicochemical similarities of krypton and xenon pose significant challenges to their separation. Reported herein is the efficient xenon capture and xenon/krypton adsorptive separation by transition metal-free zeolites under ambient conditions. The polarized environment of zeolite, denoted as local polarity, can be tuned by changing the topology, framework composition, and counter-cations, which in turn correlates with the guest-host interaction and separation performance.

Inhibition of anlotinib-induced autophagy attenuates invasion and migration by regulating epithelial-mesenchymal transition and cytoskeletal rearrangement through ATG5 in human osteosarcoma cells.

The cure rates for osteosarcoma have remained unchanged in the past three decades, especially for patients with pulmonary metastasis. Thus, a new and effective treatment for metastatic osteosarcoma is urgently needed. Anlotinib has been reported to have antitumor effects on advanced osteosarcoma.

Schottky heterojunction CeO@MXene nanosheets with synergistic type I and type II PDT for anti-osteosarcoma.

Photodynamic therapy (PDT) has shown great potential for tumor treatment as the method is noninvasive, highly selective, and causes minimal side effects. However, conventional type II PDT, which relies on O, presents poor therapeutic efficacy for hypoxic tumors due to its reliance on oxygen. Here, CeO/TiC-MXene (CeO@MXene) hybrids were successfully designed by growing CeO using TiC-MXene (MXene) nanosheets.

Precise Confinement and Position Distribution of Atomic Cu and Zn in ZSM-5 for CO Hydrogenation to Methanol.

CuZn-based catalysts are widely used in CO hydrogenation, which may effectively convert CO to methanol and alleviate CO emission issues. The precise design of a model catalyst with a clear atomic structure is crucial in studying the relationship between structure and catalytic activity. In this work, a one-pot strategy was used to synthesize CuZn@ZSM-5 catalysts with approximately two Cu atoms and one Zn atom per unit cell.

Osteoclast Cancer Cell Metabolic Cross-talk Confers PARP Inhibitor Resistance in Bone Metastatic Breast Cancer.

Unlabelled: The majority of patients with late-stage breast cancer develop distal bone metastases. The bone microenvironment can affect response to therapy, and uncovering the underlying mechanisms could help identify improved strategies for treating bone metastatic breast cancer. Here, we observed that osteoclasts reduced the sensitivity of breast cancer cells to DNA damaging agents, including cisplatin and the PARP inhibitor (PARPi) olaparib.

Dual-Confinement Effect of Nanocages@Nanotubes Suppresses Polysulfide Shuttle Effect for High-Performance Lithium-Sulfur Batteries.

The shuttle effect of lithium polysulfides (LiPSs) severely hinders the development and commercialization of lithium-sulfur batteries, and the design of high-conductive carbon fiber-host material has become a key solution to suppress the shuttle effect. In this work, a unique Co/CoN-carbon nanocages@TiO-carbon nanotubes structure (NC@TiO-CNTs) is constructed using an electrospinning and nitriding process. Lithium-sulfur batteries using NC@TiO-CNTs as cathode host materials exhibit high sulfur utilization (1527 mAh g at 0.