Strong Dipole Moments and Increased Charge Transfer in Polymer-Based Solid Electrolyte Enable Wide-Temperature Solid-State Lithium Metal Batteries.

The development of solid electrolyte interfaces (SEI) using lithium and nitrate salts represents a promising approach to enhancing the performance of lithium metal batteries (LMBs). However, the inherent stability of lithium and nitrate salts often results in incomplete decomposition, leading to the formation of inhomogeneous SEI that degrade battery performance. In this study, a strong dipole moment and increased charge transfer strategy are used, which can effectively catalyze the decomposition of NO and TFSI and accelerate the migration of Li, as well as the formation of LiN-LiF-rich SEI.

Mediating role of systemic inflammation on the association between periodontitis and gestational diabetes mellitus: a cross-sectional study.

Objectives: This study aimed to explore the relationship between periodontitis and gestational diabetes mellitus (GDM) and to ascertain the role of systemic inflammation in mediating this association.

Methods: Data from 5,283 women of reproductive age ranging from 20 to 44 years were retrieved from the National Health and Nutrition Examination Survey (NHANES) III (1988-1994) and NHANES 2009-2014 cycles. The female participants were categorized into three groups: non-diabetes, DM, and GDM.

Intestinal barrier restoration in UC: dietary protein/peptide mediate microbiota-Trp-AhR axis and food processing implications.

The incidence and prevalence of UC are increasing due to changes in diet and lifestyle. An increasing number of studies have suggested that the intestinal barrier is a key factor in the occurrence and development of UC, which is closely related to gut microbiota, the tryptophan (Trp) metabolism pathway, and aryl hydrocarbon receptor (AhR) activation. This review summarizes the current knowledge on the impact of the intestinal barrier on UC.

Lignin polymerization: towards high-performance materials.

Lignocellulosic biomass is the only sufficiently available resource for the sustainable development of the bioeconomy. Among the main components of lignocellulose, lignin has a tremendous potential to serve as a natural aromatic polymer resource due to the vast amounts of lignin available from industrial processes. However, commercial application of lignin is still limited and represents only a minor fraction of the potential utilization of approximately 20 million tons that can readily be isolated from spent pulping liquors and obtained as a residue from lignocellulosic biorefineries.

EGFL6 Promotes Angiogenesis and Odontogenesis in Pulp Regeneration via MAPK Signaling Pathways.

Objectives: Epidermal growth factor-like domain-containing protein 6 (EGFL6) is a member of the epidermal growth factor superfamily. It has been reported that it can enhance the osteogenic differentiation potential of stem cells and stimulate angiogenesis. However, its effects on the regulation of odontogenic differentiation of dental pulp stem cells (DPSCs) have not been studied.

Sulfur-doped crown ether graphane for enhanced helium separation.

Efficient helium (He) separation is essential for its application in high-tech industries, but existing separation membranes often exhibit limited selectivity and efficiency. This study proposes an effective strategy to enhance He separation performance using a sulfur-doped crown ether graphane membrane (CG-S6). Through first-principles calculations, we systematically assessed the separation barriers and selectivity of CG-S6 against five common atmospheric gases (He, Ne, Ar, N, and CH).

Gut microbiota of patients with post-stroke depression in Chinese population: a systematic review and meta-analysis.

Background: Evidence of changes in the composition and function of the gut microbiota (GM) in post-stroke depression (PSD) patients is gradually accumulating. This study aimed to systematically evaluate the relationship between PSD and GM.

Methods: We searched in PubMed, Web of Science, Embase, Cochrane databases, Wangfang, VIP, CBM, and CNKI from the establishment of the database to April 17, 2024, and systematic review and meta-analysis were performed to investigate the differences of GM between patients with PSD spectrum and healthy controls (HC) or stroke spectrum.

To explore the potential combined treatment strategy for colorectal cancer: Inhibition of cancer stem cells and enhancement of intestinal immune microenvironment.

Background: The antibiotic salinomycin, a well-known cancer stem cell inhibitor, may impact the diversity of the intestinal microbiota in colorectal cancer (CRC) mice, which plays a pivotal role in shaping the immune system. This study explores the anti-cancer effects and mechanisms of combining salinomycin and fecal microbiota transplantation (FMT) in treating CRC.

Methods: FMT was given via enema, while salinomycin was injected intraperitoneally into the CRC mouse model induced by azoxymethane/dextran sodium sulfate.

Identification and validation of mitochondria-related LncRNA signatures as a novel prognostic model for glioma.

A predictive model for long-term survival is needed, and mitochondrial dysfunction is a key feature of cancer metabolism, though its link to glioma is not well understood. The aim of this study was to identify the molecular characteristics associated with glioma prognosis and explore its potential function. We analyzed RNA-seq data from The Cancer Genome Atlas and identified differentially expressed mitochondrial long noncoding RNAs (lncRNAs) using R's 'limma' package.

Prognostic modeling of disulfidptosis gene-associated lncRNAs aids in identifying the tumor microenvironment and guiding the selection of therapy.

Introduction: Gliomas, a type of malignant tumor, are marked by a short survival period and an unfavorable prognosis. Disulfide stress, which arises from an overabundance of intracellular cystine, can initiate disulfidoptosis, an emerging form of cell death. The link between gliomas and disulfidoptosis has not been extensively explored.

Optimal dietary vitamin B1 content enhanced egg production, eggshell thickness, and serum antioxidant status in breeder geese.

Objective: This study aimed to evaluate the effects of vitamin B1 (VB1) supplementation on laying performance, egg quality, serum biochemical parameters, antioxidant status, and nutrient digestion in breeder geese.

Methods: A total of 150 geese (30 males and 120 females, aged 34 weeks) were randomly assigned to 6 dietary treatment groups, each 5 replicates of 5 birds (1 male and 4 females). The geese were fed a basal diet supplemented with 0 (control), 1, 2, 3, 4, or 5 mg/kg of VB1 for 10 weeks.

Novel human single-domain antibodies exert potent anti-tumor activity by targeting EGF-like repeat epitope of EpCAM.

Introduction: EpCAM (Epithelial cell adhesion molecule) is a key cancer stem cell marker involved in cancer progression, making it an important target for both diagnosis and therapy. Despite efforts using anti-EpCAM monoclonal antibodies (mAbs), their anti-tumor effects have been limited. Single-domain antibodies (sdAbs), in contrast, offer advantages such as efficient tumor penetration and reduced immunogenicity.

Baveno VI-SSM stratifies the risk of portal hypertension-related events in patients with HBV-related cirrhosis.

Background/aims: Cirrhotic patients with liver stiffness measurement (LSM) <20 kPa and platelet count ≥150×109/L (Baveno VI criteria), otherwise spleen stiffness measurement (SSM) ≤40 kPa (Baveno VI-SSM criteria) can avoid endoscopy screening; however, no prospective data for their hepatic outcomes.

Methods: Compensated cirrhosis with HBV were prospectively enrolled from April 2019 to April 2022 and followed until July 2023. All patients underwent LSM, SSM and esophagogastroduodenoscopy assessment.

Disulfidptosis-related immune patterns predict prognosis and characterize the tumor microenvironment in oral squamous cell carcinoma.

Background: Establishing a prognostic risk model based on immunological and disulfidptosis signatures enables precise prognosis prediction of oral squamous cell carcinoma (OSCC).

Methods: Differentially expressed immune and disulfidptosis genes were identified in OSCC and normal tissues. We examined the model's clinical applicability and its relationship to immune cell infiltration.

Macrophage Membrane-Encapsulated Carbon Dots for Precise Targeting Diagnosis and Treatment of Bacterial Infections.

How to accurately diagnose and treat bacterial infections in vivo remains a huge challenge. Therefore, we have developed a targeted delivery nanosystem by coextruding the pretreated macrophage membrane of with carbon dots (M@CD). The M@CD nanosystem demonstrates potent antibacterial effects both in vivo and in vitro through the generation of reactive oxygen species (ROS).

Nonylphenol promotes epithelial-mesenchymal transition in colorectal cancer cells by upregulating miR-151a-3p.

Nonylphenol (NP) is a common environmental contaminant and endocrine disruptor. Our previous research demonstrated that NP could promote the proliferation and epithelial-mesenchymal transition (EMT) of colorectal cancer (CRC) cells; however, the specific mechanism remains unclear. miRNA sequencing revealed that NP upregulated the expression levels of microRNA(miR)-151a-3p in CRC.

Biomimetic Micro-Nanostructured Evaporator with Dual-Transition-Metal MXene for Efficient Solar Steam Generation and Multifunctional Salt Harvesting.

Solar-driven interfacial evaporation is one of the most attractive approaches to addressing the global freshwater shortage. However, achieving an integrated high evaporation rate, salt harvesting, and multifunctionality in evaporator is still a crucial challenge. Here, a novel composite membrane with biomimetic micro-nanostructured superhydrophobic surface is designed via ultrafast laser etching technology.

Deep active learning for multi label text classification.

Given a set of labels, multi-label text classification (MLTC) aims to assign multiple relevant labels for a text. Recently, deep learning models get inspiring results in MLTC. Training a high-quality deep MLTC model typically demands large-scale labeled data.

Graphitic Carbon Nitride Enters the Scene: A Promising Versatile Tool for Biomedical Applications.

Graphitic carbon nitride (g-CN), since the pioneering work on visible-light photocatalytic water splitting in 2009, has emerged as a highly promising advanced material for environmental and energetic applications, including photocatalytic degradation of pollutants, photocatalytic hydrogen generation, and carbon dioxide reduction. Due to its distinctive two-dimensional structure, excellent chemical stability, and distinctive optical and electrical properties, g-CN has garnered a considerable amount of interest in the field of biomedicine in recent years. This review focuses on the fundamental properties of g-CN, highlighting the synthesis and modification strategies associated with the interfacial structures of g-CN-based materials, including heterojunction, band gap engineering, doping, and nanocomposite hybridization.

Factors Influencing Chloride Ion Diffusion in Reinforced Concrete Structures.

Reinforced concrete structures are prone to the corrosion of steel bars when exposed to chloride-rich environments, which can severely impact their durability. To address this issue, a comprehensive understanding of the factors influencing chloride ion diffusion in concrete is essential. This paper provides a summary of recent domestic and foreign research on chloride ion transport in concrete, focusing on six key factors: water-binder ratio, additive content, crack width, ambient temperature, relative humidity, and dry-wet cycles.

H-NMR-based metabolomics reveals the preventive effect of polysaccharides on diabetes in Zucker diabetic fatty rats.

The primary objective of this investigation was to explore the beneficial impacts of polysaccharide (EP) on dysglycemia in Zucker diabetic fatty (ZDF) rats, while also shedding light on its potential mechanism using H-NMR-based metabolomics. The results demonstrated a noteworthy reduction in fasting blood glucose (FBG, 46.3%), fasting insulin (50.

Solar-Driven Drum-Type Atmospheric Water Harvester Based on Bio-Based Gels with Fast Adsorption/Desorption Kinetics.

Sorption-based atmospheric water harvesting is an attractive technology for exploiting unconventional water sources. A critical challenge is how to facilitate fast and continuous collection of potable water from air. Here, a bio-based gel (cellulose/alginate/lignin gel, CAL gel), resulting from the integration of a whole biomass-derived polymer network with lithium chloride is reported.

Cellulose-derived raw materials towards advanced functional transparent papers.

Pulp and paper are gradually transforming from a traditional industry into a new green strategic industry. In parallel, cellulose-derived transparent paper is gaining ground for the development of advanced functional materials for light management with eco-friendly, high performance, and multifunctionality. This review focuses on methods and processes for the preparation of cellulose-derived transparent papers, highlighting the characterization of raw materials linked to responses to different properties, such as optical and mechanical properties.