IEEE Trans Pattern Anal Mach Intell
June 2025
Scene text recognition (STR) methods have struggled to attain high accuracy and fast inference speed. Auto-Regressive (AR)-based models implement the recognition in a character-by-character manner, showing superiority in accuracy but with slow inference speed. Alternatively, Parallel Decoding (PD)-based models infer all characters in a single decoding pass, offering faster inference speed but generally worse accuracy.
View Article and Find Full Text PDFMulti-modal models have shown appealing performance in visual recognition tasks, as free-form text-guided training evokes the ability to understand fine-grained visual content. However, current models cannot be trivially applied to scene text recognition (STR) due to the compositional difference between natural and text images. We propose a novel instruction-guided scene text recognition (IGTR) paradigm that formulates STR as an instruction learning problem and understands text images by predicting character attributes, e.
View Article and Find Full Text PDFAnn Med
December 2025
Background: Yigu decoction (YGD) is a traditional Chinese medicine prescription for the treatment of osteoporosis, although many clinical studies have confirmed its anti-OP effect, but the specific mechanism is still not completely clear.
Methods: In this study, through the methods of network pharmacology and molecular docking, the material basis and action target of YGD in preventing and treating OP were analyzed, and the potential target and mechanism of YGD in preventing and treating OP were clarified by TMT quantitative protein and experiment.
Results: Network pharmacology and molecular docking revealed that the active components of YGD were mainly stigmasterol and flavonoids.
Front Pharmacol
November 2024
Background: Postmenopausal osteoporosis (PMOP) is a serious condition that affects elderly individuals. Our previous study revealed that Yigu decoction (YGD) effectively improved bone mineral density (BMD) in elderly individuals, but the mechanism underlying this effect remains unclear. In this study, we investigated the relationships among YGD, microRNAs (miRNAs), and bone metabolism by assessing the effects of YGD on the miRNA levels in patient plasma to provide a scientific basis for treating PMOP with YGD.
View Article and Find Full Text PDFObjective: This study aimed to explore the research trends of percutaneous endoscopic lumbar discectomy in treating lumbar disc herniation using bibliometrics over the past ten years.
Methods: Relevant publications on the clinical application of percutaneous endoscopic lumbar discectomy in lumbar disc herniation were searched in the Web of Science Core Collection. Subsequently, the characteristics of all these articles were collected.
Front Cell Infect Microbiol
July 2023
Background: Disordered gut microbiota (GM) structure and function may contribute to osteoporosis (OP). This study explores how traditional Chinese medicine (TCM) intervention affects the structure and function of the GM in patients with OP.
Method: In a 3-month clinical study, 43 patients were randomly divided into two groups receiving conventional treatment and combined TCM (Yigu decoction, YGD) treatment.
PeerJ Comput Sci
January 2023
Image super-resolution (SR) significantly improves the quality of low-resolution images, and is widely used for image reconstruction in various fields. Although the existing SR methods have achieved distinguished results in objective metrics, most methods focus on real-world images and employ large and complex network structures, which are inefficient for medical diagnosis scenarios. To address the aforementioned issues, the distinction between pathology images and real-world images was investigated, and an SR Network with a wider and deeper attention module called Channel Attention Retention is proposed to obtain SR images with enhanced high-frequency features.
View Article and Find Full Text PDFIntroduction: As populations age, osteoporosis has become a hot topic of global public concern. The beneficial effects of traditional Chinese exercises on the musculoskeletal system have been demonstrated. However, previous research findings on osteoporosis are inconsistent, and it is unclear which type of exercise and its frequency and duration have the best effect on osteoporosis.
View Article and Find Full Text PDFBackground: Tennis elbow has long been one of the most controversial subjects in orthopaedics. Many scholars thought the use of open or arthroscopic surgery was reserved for patients with refractory symptoms. Therapy with percutaneous acupotomy performed under local anaesthesia also removes degenerated tissue, releases strain, and therefore provides an alternative treatment option to surgical excision.
View Article and Find Full Text PDFJ Neurosci
July 2022
Classical forward and reverse mouse genetics require germline mutations and, thus, are unwieldy to study sleep functions of essential genes or redundant pathways. It is also time-consuming to conduct EEG/EMG-based mouse sleep screening because of labor-intensive surgeries and genetic crosses. Here, we describe a highly accurate SleepV (video) system and adeno-associated virus (AAV)-based adult brain chimeric (ABC)-expression/KO platform for somatic genetics analysis of sleep in adult male or female mice.
View Article and Find Full Text PDFBackgrounds: Traditional Chinese medicine and Western medicine combination (TCM-WMC) increased the complexity of compounds ingested.
Objective: To develop a method for screening hepatotoxic compounds in TCM-WMC based on chemical structures using artificial intelligence (AI) methods.
Methods: Drug-induced liver injury (DILI) data was collected from the public databases and published literatures.
Front Endocrinol (Lausanne)
February 2022
Diabetic retinopathy, the most serious ocular complication of diabetes, imposes a serious economic burden on society. Automatic and objective assessment of vessel changes can effectively manage diabetic retinopathy and prevent blindness. Optical coherence tomography angiography (OCTA) metrics have been confirmed to be used to assess vessel changes.
View Article and Find Full Text PDFClin Proteomics
October 2021
Background: Osteoporosis (OP) is a systemic bone disease characterized by decreased bone mass, destruction of the bone tissue microstructure, increased bone brittleness and an increased risk of fracture. OP has a high incidence rate and long disease course and is associated with serious complications. Yigu decoction (YGD) is a compound prescription in traditional Chinese medicine that is used to treat OP.
View Article and Find Full Text PDFNeurocomputing (Amst)
October 2021
The outbreak and rapid spread of coronavirus disease 2019 (COVID-19) has had a huge impact on the lives and safety of people around the world. Chest CT is considered an effective tool for the diagnosis and follow-up of COVID-19. For faster examination, automatic COVID-19 diagnostic techniques using deep learning on CT images have received increasing attention.
View Article and Find Full Text PDFBackground: This study aims to evaluate the association between serum alkaline phosphatase (ALP), calcium (Ca) and phosphorus (P), C-reactive protein (CRP) and D-dimer (D-D), and hemoglobin (Hb) in postoperative and preoperative osteoporotic hip fracture elderly patients.
Methods: A total of 32 operation patients with osteoporotic hip fracture over the age of 65 years old were admitted to the orthopedic unit and prospectively evaluated. All patients were treated according to specific protocols, according to the type of fracture.
Lumbar decompressive surgery is the gold standard treatment for lumbar spinal stenosis. Minimally invasive surgical techniques have been introduced with the aim of reducing the morbidity associated with open surgery. The purpose of the present study was to systematically search the literature and perform a meta-analysis of studies comparing the outcomes between biportal endoscopic technique and microscopic technique for lumbar canal stenosis decompression.
View Article and Find Full Text PDFJ Invest Surg
April 2021
Neural Netw
December 2018
Distant supervised relation extraction is an important task in the field of natural language processing. There are two main shortcomings for most state-of-the-art methods. One is that they take all sentences of an entity pair as input, which would result in a large computational cost.
View Article and Find Full Text PDFThe aim of the present study was to evaluate the relative functional volume of bilateral lumbar multifidus (LM) muscles across different stages and ages of patients with lumbar disc herniation (LDH). The relative functional volumes of LM muscles in both non-affected and affected sides in the L4-L5 and L5-S1 segmental level were measured in a resting prone position, and visual analogue score (VAS) for pain and Japanese Orthopedic Association (JOA) scores were recorded. The correlation between changes in the relative net volume of LM muscles and times of onset, ages, VAS and JOA scores were analyzed.
View Article and Find Full Text PDFNeuroinformatics
October 2018
How to read Uyghur text from biomedical graphic images is a challenge problem due to the complex layout and cursive writing of Uyghur. In this paper, we propose a system that extracts text from Uyghur biomedical images, and matches the text in a specific lexicon for semantic analysis. The proposed system possesses following distinctive properties: first, it is an integrated system which firstly detects and crops the Uyghur text lines using a single fully convolutional neural network, and then keywords in the lexicon are matched by a well-designed matching network.
View Article and Find Full Text PDFMolasses alcohol wastewater (MAW) is difficult to be bio-treated and converted into biogas. In this study, MAW mixed with pig manure (PM) in different ratios was co-digested. Biogas production, chemical oxygen demand (COD) removal and the structure of microbial communities were monitored in the process.
View Article and Find Full Text PDFObjective: To study the effect of inactivated and un-inactivated pharmaco-serum of diabetic rats fed with Chinese herbs Qianggubao decoction on the proliferation of osteoblast cells (OB)cultured in vitro.
Methods: OB was isolated from the skull of newly born SD rats aged 1 to 2 days by means of Trypsin-collagenase digestion and identified by image analysis under inverted microscope, V-G collagen staining, ALP staining, calcification nod staining etc. After the OB was identified, in activated and un-inactivated pharmaco-serum of diabetic rats fed with Qianggubao decoction of ferent phase (rats were fed with medicine 3 days or 5 days after last fed with medicine 1 hour or 3 hours) and concentration (5%, 10%, 20%) were added to the OB and incubated.
Objective: To investigate the optimum phase and dose of pharmaco-serum of diabetic rats fed with Qianggubao decoction ([Chinese characters: see text]) on the differentiation and mineralization of osteoblast (OB). METHODS (OB) was isolated from the skull of 10 newly born SD rats aged 1 to 2 days by means of Trypsin-collagenase digestion. After the OB was identified, different kinds of pharmaco-serum of diabetic rats fed with inactive Qianggubao decoction ([Chinese characters: see text]) of different phase (rats were fed with medicine three days or five days after last fed with medicine one hour or three hours) and concentration (5%, 10%, 20%) were added to the OB and incubated.
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