Soybean Confers Salt-Alkali Stress Tolerance in Transgenic Plants.

In order to mitigate the reduction in soybean yield caused by soil salinization, a soybean gene, , which promotes plant tolerance to salt-alkali stress, was identified in this study. The STRING database was used to predict the interaction between GmSNF4 and GmPKS4. The gene was experimentally shown to be involved in salt-alkali stress tolerance.

Genetic structure, dispersal pathways, and northern expansion predictions of Solenopsis invicta: A two-decade journey through China's diverse landscapes.

The red imported fire ant, Solenopsis invicta, has invaded China for over two decades, advancing northwest from Guangdong to the Yangtze River coast at 30.8° N latitude. A decade since the last genetic analysis, this study revisits the species' genetic structure and invasion trajectory amidst intensifying selective pressures.

Scutellarin mitigates LPS-ATP-induced cardiomyocyte pyroptosis through the inhibition of the NLRP3/caspase-1/GSDMD signalling pathway.

Scutellarin has a good myocardial protective effect. However, the underlying mechanism of scutellarin on cardiomyocyte pyroptosis remains unclear. In this study, we elucidated the mechanism of scutellarin to protect the injured myocardium.

Nomogram for predicting the severity of high-risk plaques in acute coronary syndrome.

Background: The CLIMA study [Relationship between Optical Coherence Tomography (OCT) Coronary Plaque Morphology and Clinical Outcome; NCT02883088] introduced the concept of high-risk plaque (HRP) and demonstrated that HRP was associated with a high risk of major coronary events. HRP is defined by four simultaneous characteristics: minimum lumen area (MLA) <3.5 mm, fibrous cap thickness (FCT) <75 μm, lipid arc circumferential extension >180°, and macrophage infiltration.

Ventricular Arrhythmias Originating From Different Portions of the Anterior Interventricular Vein: Electrocardiographic Characteristics and Ablation Strategy.

Introduction: The anterior interventricular vein (AIV) is an important and recognized source of ventricular arrhythmias (VAs) within the coronary venous system. However, no studies have specifically investigated the electrocardiographic (ECG) characteristics and ablation strategies for VAs originating from the AIV.

Objective: This study aimed to investigate the ECG characteristics and optimal ablation strategies for VAs originating from the AIV.

Dynamic change in maternal cardiac function during pregnancy.

Background: Pregnant women experience various physiological changes that, if uncompensated, may result in varying degrees of cardiac dysfunction, and adverse pregnancy outcomes. Left ventricular (LV) global longitudinal strain (GLS) and P-wave to A' duration on tissue Doppler imaging (PA-TDI) have been shown to be able to detect subtle cardiac dysfunction.

Methods: The present study was a prospective cross-sectional study.

Characteristics of soil seed banks and their influencing factors in communities at different altitudes on the eastern foothills of Helan Mountain, China.

is a national key protected plant species in the eastern foothills of the Helan Mountains. We established sample plots in communities at altitudes of 1236, 1350, 1477, and 1603 m. Through field surveys and indoor seed bank germination experiments, we investigated the characteristics of soil seed banks in community across different altitudes and their influencing factors.

[Serological and Molecular Biological Detection of RhD Variants].

Objective: To analyze the genotyping and sequencing results of RhD serology negative samples in the clinic, and to further explore the laboratory methods for RhD detection, in order to provide a basis for clinical precision blood transfusion.

Methods: A total of 27 200 whole blood samples were screened for RhD blood group antigen using microcolumn gel card method.Serologic RhD-negative confirmation tests were performed on blood samples that were negative for RhD on initial screening using three different clonal strains of IgG anti-D reagents.

Multi-Wavelength Achromatic 3D Meta-holography with Zoom Function.

With the development of nanofabrication technology, meta-holography has shown unprecedented potential for light regulation. However, due to the wavelength mismatch, chromatic aberrations are inevitable in multi-wavelength meta-holography. Moreover, since the meta-hologram is difficult to refresh, zoom meta-holography has not been reported to date.

Cadmium disrupted homeostasis of proximal renal tubular cells via targeting ATF4-CHOP complex into the nucleus.

Cadmium, a ubiquitous toxic metal and environmental pollutant, is associated with several renal metabolic disorders and disrupts the homeostasis of kidneys in humans and animals. However, the precise molecular mechanism remains poorly elucidated. The present study investigated the role of the ATF4-CHOP nuclear transcriptional axis and its interactions with cellular pathways in cadmium-induced nephrotoxicity.

[Effects of acupuncture on Bell's palsy patients in the acute stage based on the surface electromyography].

Objectives: To investigate the effects of acupuncture on the muscle strength and fatigue levels of facial muscles of the patients with Bell's facial paralysis in the acute stage, using surface electromyography.

Methods: Sixty patients diagnosed with acute Bell's facial paralysis were randomly assigned to an observation group (30 cases) and a control group (30 cases). In the observation group, the routine acupuncture was applied to Quanliao (SI18), Yangbai (GB14), Yifeng (TE17), Jiache (ST6) and Dicang (ST4) on the affected side and Hegu (LI4) on the healthy side.

Impact of zero-markup consumable policy and national procurement of coronary stents on hospitalization expenses: an interrupted time series analysis.

Background: After the successful reforms of drug pricing, China has implemented two significant reforms to reduce medical consumables expenses: the elimination of markup on prices (zero-markup policy) and the implementation of centralized procurement of high-value medical consumables (national procurement policy). The public hospitals in Guangdong province had implemented the zero-markup policy and national procurement policy for coronary stents. Currently, research on the zero-markup consumable policy and national procurement of coronary stents for medical consumables at the hospital level lacks analysis of changes in cost structures (other expenses) and studies on hospital response strategies.

Real-time holographic camera for obtaining real 3D scene hologram.

As a frontier technology, holography has important research values in fields such as bio-micrographic imaging, light field modulation and data storage. However, the real-time acquisition of 3D scenes and high-fidelity reconstruction technology has not yet made a breakthrough, which has seriously hindered the development of holography. Here, a novel holographic camera is proposed to solve the above inherent problems completely.

Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges.

Purpose Of Review: Obesity is increasingly recognized as a significant factor impacting the outcomes of fertility-preserving therapies for endometrial cancer (EC). This review explores the effects of glycolipid metabolism on EC and its relationship with body weight. We will examine how excess body weight influences the effectiveness of fertility-preserving treatments and discuss potential mechanisms for effective weight management.

[Impact of climate change on the potential geographical distribution of subsp. ].

subsp. is an important resource plant with considerable medicinal, economic, and ecological value, and an indicator species in the transition zones between forests and grasslands. Predicting the potential geographic distribution of subsp.

Reductive coupling of azonaphthalenes for the synthesis of BINAMs a diboron-enabled [5,5]-sigmatropic rearrangement.

The [5,5]-sigmatropic rearrangement is a less-studied reaction and may be strategically utilized to devise unique synthetic processes. Herein, we document a diboron-enabled [5,5]-sigmatropic rearrangement for practical synthesis of BINAM derivatives. Mechanistically, a concerted activation of azonaphthalenes by diboron creates a unique ten-membered transition state, which subsequently triggers a [5,5]-sigmatropic rearrangement.

A New Insight into the Mechanism of Atrazine-Induced Neurotoxicity: Triggering Neural Stem Cell Senescence by Activating the Integrated Stress Response Pathway.

Atrazine (AT), a widely utilized chemical herbicide, causes widespread contamination of agricultural water bodies. Recently, exposure to AT has been linked to the development of age-related neurodegenerative diseases (NDs), suggesting its neurotoxicity potential. As an endocrine disruptor, AT targets the hypothalamus, a crucial part of the neuroendocrine system.

Case report: A rare EBV-associated T/NK cell monomorphic posttransplant lymphoproliferative disorder.

Background: Kidney transplantation (KT) is the best treatment for patients with end-stage renal disease. However, postoperative complications remain the main issues faced during KT recovery period. Posttransplant lymphoproliferative disorders (PTLD) are one of the severe and life-threatening complications that occur after KT while the recipient is undergoing immunosuppressive therapy.

[Comparative Life Cycle Assessment and Carbon Footprint of Typical Hydrogen Energy Products].

To compare the environmental impact and carbon footprint of gray hydrogen, blue hydrogen, and green hydrogen, inventories were obtained through literature research. Some inventories that were not available in China were obtained through foreign inventories combined with localized power conversion. The localized end-point destructive life cycle impact assessment method was used to calculate the environmental impact potential of the raw material acquisition, transportation, and hydrogen production stages of five hydrogen products.

Lycopene mitigates atrazine-induced hypothalamic neural stem cell senescence by modulating the integrated stress response pathway.

Background: Atrazine, a widely used herbicide, has become a major pollutant in agricultural water bodies. Pesticide contamination, including atrazine, is linked to a high incidence of age-related neurodegenerative diseases, suggesting its neurotoxic potential. Lycopene, a potent antioxidant, is renowned for its diverse pharmacological effects, especially its neuroprotective properties.

Cadmium causes spleen toxicity in chickens by regulating mitochondrial unfolded protein response and nuclear receptors response.

Cadmium (Cd) is a heavy metal that pollutes the environment and threatens human and animal health via the food chain. The spleen is one of the target organs affected by Cd toxicity. However, the mechanism of Cd toxicity is not fully understood.

Correlation and predictive value of pathological complete response and ultrasound characteristic parameters in neoadjuvant chemotherapy for breast.

Background: Breast cancer ranks as one of the most prevalent malignant tumors among women, significantly endangering their health and lives. While radical surgery has been a pivotal method for halting disease progression, it alone is insufficient for enhancing the quality of life for patients.

Aim: To investigate the correlation between ultrasound characteristic parameters of breast cancer lesions and clinical efficacy in patients undergoing neoadjuvant chemotherapy (NAC).

Single-cell transcriptomics reveals writers of RNA modification-mediated immune microenvironment and cardiac resident Macro-MYL2 macrophages in heart failure.

Background: Heart failure (HF), which is caused by cardiac overload and injury, is linked to significant mortality. Writers of RNA modification (WRMs) play a crucial role in the regulation of epigenetic processes involved in immune response and cardiovascular disease. However, the potential roles of these writers in the immunological milieu of HF remain unknown.