Advances in orofacial pain research: a bibliometric analysis.

Objective: Orofacial pain has become increasingly prevalent with the advancement of society and economy. Bibliometrics, an interdisciplinary field encompassing mathematics, statistics, and information science, offers insights into the trends, research focal points, and knowledge framework of orofacial pain through quantitative analysis of relevant literature. This study aims to systematically map the evolutionary trajectory of orofacial pain research from 2000 to 2024.

The diagnostic efficiency of tissue factor pathway inhibitor 2 methylation in the detection of colorectal cancer: a systematic review and meta-analysis.

Background: Colorectal cancer (CRC) is a common malignant tumor of the digestive tract. Screening of high risk populations and early diagnosis of CRC are of great importance. Tissue factor pathway inhibitor 2 () methylation is an important indicator for screening CRC.

A Longitudinal Study of Sleep in University Freshmen: Facilitating and Impeding Factors.

Study Objectives: Establishing healthy sleeping habits is a challenge for many college students. We determined how academic schedule influenced sleep patterns across the semester, and if these are modulated by place of residence and class start times.

Methods: A longitudinal cohort study evaluated 638 freshmen over their first 20-week semester involving instructional, reading, examination and vacation weeks.

Association between objectively measured, multidimensional sleep health and cognitive function in older adults: cross-sectional wearable tracker study.

Both sleep and cognition are multidimensional constructs. Using univariate methods to examine associations between sleep and cognition may inadequately characterize the association between these arrays of variables. The current study used a multivariate approach to identify key sleep metrics and cognitive domains contributing to the maximum sleep-cognition covariance in healthy older adults.

METTL3 mediates atheroprone flow-induced glycolysis in endothelial cells.

Atheroprone flow-increased glycolysis in vascular endothelial cells (ECs) is pivotal in EC dysfunction and the initiation of atherosclerosis. Methyltransferase 3 (METTL3) is a major mA methyltransferase for RNA N6-mehtyladenosine (mA) modifications to regulate epitranscriptome and cellular functions. With the atheroprone flow upregulating METTL3 and mA RNA hypermethylation, we investigate the role of METTL3 in atheroprone flow-induced glycolysis in ECs in vitro and in vivo.

Imbibition Characteristics and Its Influencing Factors of Shale Gas Reservoirs: A Case Study of the Longmaxi Shale in Southeast Chongqing.

For the purpose of estimating the influence of reservoir pore structure, composition, imbibition fluid type, and fluid pressure on imbibition fluid amount and imbibition rate, parallel subsamples of Longmaxi Shale in southeast Chongqing were selected to carry out imbibition experiments on five kinds of solutions under pressures of 10 and 0.1 MPa. The amount of imbibition fluid entering the reservoir sample is closely related to the porosity.

Research prospect of human salivary cortisol: a bibliometric analysis.

Background: Salivary cortisol has garnered increasing attention; the aim of this study was to employ bibliometric analysis to identify key papers in this research field and to explore its current status and trends.

Methods: Data were sourced from Clarivate Analytics' Web of Science core database, utilizing the search terms 'TS = ('Salivary cortisol') AND (Human) NOT (animal)'. All articles published from January 1, 2004, to September 30, 2024, were included.

Combustion characteristics, functional groups, and gaseous emission behavior of different coals by TG-FTIR.

The combustion characteristics and gas emissions behavior of Low-calorie Indonesian coal (LC), Shaanxi coal (SC), and Datong coal (TC) were analyzed by a thermogravimetric-Fourier transform infrared spectrometer (TG-FTIR). The results showed that LC was the easiest coal to burn, followed by SC and TC. The main components of LC ash were alkali metals and alkaline earth metals (AAEMS), while SC and TC were clay minerals.

The effects of COVID-19 lockdown and reopening on rest-activity rhythms in Singaporean working adults: A longitudinal age group comparison study.

Study Objectives: COVID-19 mobility restrictions disrupted daily rhythms worldwide, but how this rhythm disruption differs across age groups is unclear. We examined the course of age-related differences in trajectories of rest-activity rhythm during the COVID-19 pandemic lockdown and reopening in Singapore. We also evaluated the association of these patterns with mental well-being.

Brain activations elicited during task-switching generalize beyond the task: A partial least squares correlation approach to combine fMRI signals and cognition.

An underlying hypothesis for broad transfer from cognitive training is that the regional brain signals engaged during the training task are related to the transfer tasks. However, it is unclear whether the brain activations elicited from a specific cognitive task can generalize to performance of other tasks, esp. in normal aging where cognitive training holds much promise.

The Emerging Importance of Sleep Regularity on Cardiovascular Health and Cognitive Impairment in Older Adults: A Review of the Literature.

The regularity of sleep/wake patterns across multiple days is emerging as an important determinant of health. However, the association between sleep regularity and health outcomes in the aging population is not well understood. The current systematic review identified 22 publications that examined the relationship between sleep regularity and selected health outcomes: cardiovascular risk, cognitive impairment, and mortality.

The Effects of Computerized Cognitive Training in Older Adults' Cognitive Performance and Biomarkers of Structural Brain Aging.

Objectives: Cognitive training (CT) has been investigated as a means of delaying age-related cognitive decline in older adults. However, its impact on biomarkers of age-related structural brain atrophy has rarely been investigated, leading to a gap in our understanding of the linkage between improvements in cognition and brain plasticity. This study aimed to explore the impact of CT on cognitive performance and brain structure in older adults.

A three-dimensional network structure of metal-based nanozymes for the construction of colorimetric sensors for the detection of antioxidants.

Although many excellent nanozymes have been developed, designing and synthesizing highly active nanozymes is still challenging. Here, we developed a metal-based nanozyme (metal = Co, Fe, Cu, Zn) with a three-dimensional network structure. It possesses excellent peroxidase activity and catalyzes the reaction between HO and TMB to produce blue oxTMB, while antioxidants have different reducing power on the oxidation product of TMB (oxTMB), which leads to different absorbance and color changes.

Flower-like 3D MoS microsphere/2D CN nanosheet composite for highly sensitive electrochemical sensing of nitrite.

Nitrite pollution poses a serious threat to human health and the environment. In this study, a reliable and selective electrochemical (EC) sensor was developed for the quantitative determination of nitrite by combining flower-like three-dimensional (3D) MoS microspheres with two-dimensional (2D) CN nanosheets. Benefiting from the synergistic effects of MoS and CN, the 3D MoS/2D CN nanocomposite displayed numerous active sites, a 3D mesoporous structure, high conductivity and excellent catalytic activity.

An efficient single shot detector with weight-based feature fusion for small object detection.

Object detection has been widely applied in various fields with the rapid development of deep learning in recent years. However, detecting small objects is still a challenging task because of the limited information in features and the complex background. To further enhance the detection accuracy of small objects, this paper proposes an efficient single-shot detector with weight-based feature fusion (WFFA-SSD).

Colorimetric identification of multiple terpenoids based on bimetallic FeCu/NPCs nanozymes.

Nanozymes have been relatively well explored, and bimetal-doped nanozymes have attracted much exploration due to their superior catalytic activity. We developed bimetallic FeCu/NPCs and Cu/NPCs nanozymes, which have good catalytic properties due to the coordination of Fe and Cu with N and P. The nanozymes acted as sensing elements in a cascade reaction system to effectively recognize seven terpenoids, including menthol (Men), paeoniflorin (Pae), camphor (Cam), paclitaxel (Pac), andrographolide (Andro), ginkgolide A (Gin A), and piperone (Pip).

Co-exposure to particulate matter and humidity increases blood pressure in hypertensive mice via the TRPV4-cPLA-COX2 pathway.

Epidemiological studies have demonstrated that particulate matter (PM) can induce or exacerbate hypertension. High relative humidity has been associated with elevated blood pressure in certain regions. However, the coupling effect of humidity and PM on elevated blood pressure and the underlying mechanisms remain unknown.

Cognitive and structural predictors of novel task learning, and contextual predictors of time series of daily task performance during the learning period.

Investigation into methods of addressing cognitive loss exhibited later in life is of paramount importance to the field of cognitive aging. The field continues to make significant strides in designing efficacious cognitive interventions to mitigate cognitive decline, and the very act of learning a demanding task has been implicated as a potential mechanism of augmenting cognition in both the field of cognitive intervention and studies of cognitive reserve. The present study examines individual-level predictors of complex skill learning and day-to-day performance on a gamified working memory updating task, the BirdWatch Game, intended for use as a cognitive intervention tool in older adults.

Exploration of new therapeutic targets for viral hepatic fibrosis, alcoholic hepatic fibrosis, and non-alcoholic hepatic fibrosis.

Background: Hepatic fibrosis is a widespread disease worldwide. Millions of people lose their lives due to hepatic fibrosis every year. The main causes of hepatic fibrosis include viral infection, alcoholism, and obesity.

Targeted delivery via albumin corona nanocomplex to renal tubules to alleviate acute kidney injury.

Renal tubular epithelial cell (RTEC) is a critical target cell for the treatment of acute kidney injury (AKI). Despite various RTEC targeting strategies using ligand modified nanoparticles (NPs) following systemic administration, the nonspecific interaction between NPs and plasma proteins greatly weakens the targeting efficiency as well as the stability of NPs. Herein, celastrol (CLT) was entrapped in D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) forming a CLT-loaded nanocomplex core (CT) with a high loading capacity of ~50%.

The prognostic value of preoperative peripheral blood inflammatory indicators for squamous cell carcinoma of tongue.

Objectives: A study was conducted to investigate the value of preoperative peripheral blood inflammatory indicators in the prediction of tongue squamous cell carcinoma (TSCC) prognosis.

Methods: This retrospective analysis included 210 patients who underwent radical resection for TSCC in the Department of Oral and Maxillofacial Surgery of The First Affiliated Hospital of Zhengzhou University from January 2010 to December 2017. Receiver operating characteristic curve was conducted to determine the best cut-off values of platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte ratio (NLR).