Glycine-mediated heavy metal leaching and calcium retention from municipal solid waste incineration fly ash: A mechanistic study.

Traditional acid washing with agents like hydrochloric and acetic acid can effectively extract heavy metals from municipal solid waste incineration fly ash (referred to as "fly ash") but also dissolve calcium, complicating subsequent resource utilization. This study proposes the use of glycine as a green leaching agent to effectively extract heavy metals while retaining calcium under mild conditions. A systematic analysis was conducted to assess the effects of glycine concentration and temperature on the efficacy of heavy metal leaching.

Cordycepin alleviates metabolic dysfunction-associated liver disease by restoring mitochondrial homeostasis and reducing oxidative stress via Parkin-mediated mitophagy.

The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) keeps rising with only a few drugs available. The present study aims to investigate the effects and mechanisms of cordycepin on MASLD. Male C57BL/6 mice were induced with a 90-day high-fat diet (HFD) and intraperitoneal administration with streptozotocin to establish MASLD murine model.

Co-treatment of municipal solid waste incineration fly ash and alumina-/silica-containing waste: A critical review.

Municipal solid waste incineration fly ash (MSWI-FA) is a hazardous by-product of the incineration process, characterized by elevated levels of heavy metals, chlorides, and dioxins. With a composition high in calcium but low in silicon/aluminum, MSWI-FA exhibits a poor immobilization effect, high energy demands, and limited pozzolanic activity when it is disposed of or reutilized alone. Conversely, alumina-/silica-containing waste (ASW) presents a chemical composition rich in SiO and/or AlO, offering an opportunity for synergistic treatment with MSWI-FA to facilitate its harmless disposal and resource recovery.

Reprogramming exosomes for immunity-remodeled photodynamic therapy against non-small cell lung cancer.

Traditional treatments against advanced non-small cell lung cancer (NSCLC) with high morbidity and mortality continue to be dissatisfactory. Given this situation, there is an urgent requirement for alternative modalities that provide lower invasiveness, superior clinical effectiveness, and minimal adverse effects. The combination of photodynamic therapy (PDT) and immunotherapy gradually become a promising approach for high-grade malignant NSCLC.

I Induced In Vivo Proteolysis by Photoswitchable azoPROTAC Reinforces Internal Radiotherapy.

Photopharmacology, incorporating photoswitches such as azobenezes into drugs, is an emerging therapeutic method to realize spatiotemporal control of pharmacological activity by light. However, most photoswitchable molecules are triggered by UV light with limited tissue penetration, which greatly restricts the in vivo application. Here, this study proves that I can trigger the trans-cis photoisomerization of a reported azobenezen incorporating PROTACs (azoPROTAC).

Radiation responsive PROTAC nanoparticles for tumor-specific proteolysis enhanced radiotherapy.

Proteolysis targeting chimeras (PROTACs) is a promising strategy for cancer therapy. However, the always-on bioactivity of PROTACs may lead to non-target toxicity, which restricts their antitumor performance. Here, we developed an X-ray radiation responsive PROTAC nanomicelle (RCNprotac) by covalently conjugating a reported small molecule PROTAC (MZ1) to hydrophilic PEG a diselenide bond-containing carbon chain, which then self-assembled into a 141.

Comparing the Performance of Three Computational Methods for Estimating the Effective Reproduction Number.

The effective reproduction number is one of the most important epidemiological parameters, providing suggestions for monitoring the development trend of diseases and also for adjusting the prevention and control policies. However, a few studies have focused on the performance of some common computational methods for . The purpose of this article is to compare the performance of three computational methods for : the time-dependent (TD) method, the new time-varying (NT) method, and the sequential Bayesian (SB) method.

Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury.

Therapeutic interventions such as synthetic drugs and microRNA (miR) modulators have created opportunities for mitigating hepatic ischemia/reperfusion injury (HIRI) by alleviating mitochondrial dysfunction. However, delivering multi-therapeutic ingredients with low toxicity to hepatocytes still lags behind its development. In this study, we endowed exosomes with delivery function to concentrate on hepatocytes for multidimensionally halting mitochondria dysfunction during HIRI.

Synthesis of layered double hydroxides from municipal solid waste incineration fly ash for heavy metal adsorption.

The process of urbanization has resulted in a continuous growth of the production of municipal solid waste, consequently leading to the increase of municipal solid waste incineration fly ash (MSWI FA) over time. This has prompted the need for effective disposal and value-added utilization strategies for MSWI FA. In this study, a hydrothermal method was employed to synthesize CaAl layered double hydroxides (LDHs) using MSWI FA as the raw material.

Use of municipal solid waste incineration fly ash as a supplementary cementitious material: CO mineralization coupled with mechanochemical pretreatment.

The use of municipal solid waste incineration fly ash, commonly referred to as "fly ash", as a supplementary cementitious material (SCM), has been explored to mitigate the CO emissions resulting from cement production. Nevertheless, the incorporation of fly ash as an SCM in mortar has been shown to weaken its compressive strength and increase the risk of heavy metal leaching. In light of these challenges, this study aims to comprehensively evaluate the influence of CO pressure, temperature, and residual water/binder ratio on the CO uptake and compressive strength of mortar when combined with fly ash.

Will a boom be followed by crash? A new systemic risk measure based on right-tail risk.

In this study, we demonstrate that high short-term gains on the A-share market may lead to significant losses in the future and potentially cause a market catastrophe. To study the accumulation, outbreak, and cross-sector spillover process of systemic risk in the Chinese stock market, we define right-tail risk as a large rally process that may lead to left-tail losses in the future and construct a tail volatility spillover network by distinguishing between left-tail and right-tail risk. In the risk accumulation process, the market expectation bias of common shocks considerably magnifies heterogeneity risk, and in the risk outbreak and spillover processes, the greatest systemically important and systemically susceptible sectors are banking and information technology, respectively.

In-situ release and sequestration of CO in cement composites using LTA zeolites.

This paper investigates the impact of in-situ release and sequestration of CO on the compressive strength, volume of permeable voids, phase change, hydration reaction, and micro-morphology of cement mortars. Two Linde Type A (LTA) zeolites with micro-pore dimensions of 5 Å and 4 Å (i.e.

Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells.

Non-alcoholic fatty liver disease (NAFLD) held a high global prevalence in recent decades. Hepatic lipid deposition is the major characteristic of NAFLD. We aim to explore the mechanisms of psoralen on lipid deposition in NAFLD.

Adsorptive removal of organic dyes via porous materials for wastewater treatment in recent decades: A review on species, mechanisms and perspectives.

Organic dyes, a type of high toxic and carcinogenic chemicals that present severe threats to human and aquatic life, are the most commonly seen organic pollutants in wastewater of industries such as textile, rubber, cosmetic industry etc. Various techniques for the removal of dyes are compared in this review. Adsorption has proven to be a facile and promising approach for the removal of dyes in wastewater.

Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.

Background: Docetaxel (DTX) exhibits antitumor effects against breast cancer by stabilizing microtubules and increasing the accumulation of reactive oxygen species (ROS). DTX extravasation during infusion often causes skin injury. The present study aimed to investigate the effects and mechanisms of icaritin (ICT) on DTX-induced skin injury.

Icaritin Attenuates Lipid Accumulation by Increasing Energy Expenditure and Autophagy Regulated by Phosphorylating AMPK.

Background And Aims: Lipid accumulation is the major characteristic of non-alcoholic fatty liver disease, the prevalence of which continues to rise. We aimed to investigate the effects and mechanisms of icaritin on lipid accumulation.

Methods: Cells were treated with icaritin at 0.

Naringenin Attenuates Non-Alcoholic Fatty Liver Disease by Enhancing Energy Expenditure and Regulating Autophagy via AMPK.

The prevalence of non-alcoholic fatty liver disease (NAFLD) keeps growing recently. To investigate the effects and mechanisms of naringenin (NAR) on NAFLD. High-fat diet (HFD)-induced NAFLD rats were orally administered with NAR at 10, 30, and 90 mg/kg for 2 weeks.

Morphology-Reserved Synthesis of Discrete Nanosheets of CuO@SAPO-34 and Pore Mouth Catalysis for One-Pot Oxidation of Cyclohexane.

Discrete nanosheets of silicon-doped AlPO molecular sieves (SAPO-34) with a thickness of ≈7 nm have been prepared through morphology-reserved synthesis with a lamellar aluminum phosphate as precursor. Cages of the nanosheets are in situ incorporated with copper oxide clusters. The CuO@SAPO-34 nanosheets exhibit a large external surface area with a high number of (010) channel pores on the surface.

Environmentally persistent free radicals in PM: a review.

Environmentally persistent free radicals (EPFRs) are a new class of pollutants that are long-lived in fine particles (PM), i.e., their 1/e lifetime ranges from days to months (or even infinite).

Set Stabilization of Probabilistic Boolean Control Networks: A Sampled-Data Control Approach.

This article investigates the set stabilization of probabilistic Boolean control networks (PBCNs) under sampled-data (SD) state-feedback control within finite and infinite time, respectively. First, the algorithms are, respectively, proposed to find the sampled point set and the largest sampled point control invariant set (SPCIS) of PBCNs by SD state-feedback control. Based on this, a necessary and sufficient criterion is proposed for the global set stabilization of PBCNs by SD state-feedback control within finite time.

A comparative study of mechanisms of the adsorption of CO confined within graphene-MoS nanosheets: a DFT trend study.

The space within the interlayer of 2-dimensional (2D) nanosheets provides new and intriguing confined environments for molecular interactions. However, atomic level understanding of the adsorption mechanism of CO confined within the interlayer of 2D nanosheets is still limited. Herein, we present a comparative study of the adsorption mechanisms of CO confined within graphene-molybdenum disulfide (MoS) nanosheets using density functional theory (DFT).

Fabrication of β-cyclodextrin modified mesostructured silica coated multi-walled carbon nanotubes composites and application for paraben removal.

In this work, the novel β-cyclodextrin modified mesostructured silica coated multi-walled carbon nanotubes (MWCNTs) composites were synthesized and applied for the removal of parabens in aqueous solution. The prepared MWCNTs/SiO/β-CD composites were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy and thermogravimetric analysis. The effects of the amount of adsorbent, pH and elution solvents on the removal efficiency of parabens from water solutions were investigated.

Temporal and spatial variation in major ion chemistry and source identification of secondary inorganic aerosols in Northern Zhejiang Province, China.

To investigate the seasonal and spatial variations of ion chemistry of fine particles in Northern Zhejiang Province (NZP), China, one year-long field sampling was conducted at four representative sites (two urban, one suburb, and one rural sites) in both cities of Hangzhou and Ningbo from December 2014 to November 2015. Twelve water soluble inorganic ions (WSII) were characterized in this comprehensive study. The annual average of PM concentration in NZP as overall was 66.

Radicals and molecular products from the gas-phase pyrolysis of lignin model compounds. Cinnamyl alcohol.

The experimental results on detection and identification of intermediate radicals and molecular products from gas-phase pyrolysis of cinnamyl alcohol (CnA), the simplest non-phenolic lignin model compound, over the temperature range of 400-800 °C are reported. The low temperature matrix isolation - electron paramagnetic resonance (LTMI-EPR) experiments along with the theoretical calculations, provided evidences on the generation of the intermediate carbon and oxygen centered as well as oxygen-linked, conjugated radicals. A mechanistic analysis is performed based on density functional theory to explain formation of the major products from CnA pyrolysis; cinnamaldehyde, indene, styrene, benzaldehyde, 1-propynyl benzene, and 2-propenyl benzene.