spp. is one of the most important salt-alkali resistant tree species in the Yellow River region of China. However, the limited number of superior families and individuals, as well as the lack of a well-established parent selection system for hybrid breeding, have seriously constrained the improvement of seed orchards and the construction of advanced breeding populations.
View Article and Find Full Text PDFThe size of fat globules in ruminant milk to some extent affects the nutritional quality of dairy products and plays potential roles in infant and adult health. Lipid droplets (LD) in mammary epithelial cells are the precursors of milk fat globules (MFG). However, it is unclear what happens to proteins during the transformation process from LD to MFG, and little is known about the regulation of LD diameter in vivo.
View Article and Find Full Text PDFThis study examines the impact of vegetation structure on bird species richness and diversity across four urban parks in Chaoyang District, Beijing. Throughout the year, using the Point Count Method (PCM), a total of 68 bird species and 4279 individual observations were recorded, with surveys conducted across all four seasons to capture seasonal variations. The parks with more complex vegetation, such as those with a higher tree canopy cover of species like poplars, ginkgo, and Chinese pines, exhibited higher bird species richness.
View Article and Find Full Text PDFIn the multi-target tracking (MTT) problem of sensor networks, inconsistencies in sensor fields of view and target labeling can significantly degrade tracking accuracy. These issues are particularly acute in clustered sensor networks. So, this paper presents an MTT algorithm to address the tracking problem in clustered sensor networks with the aforementioned two issues.
View Article and Find Full Text PDFSpinal muscular atrophy is a hereditary disorder leading to severe neuromuscular impairment. With the introduction of disease-modifying therapies in recent years, the role of biomarkers has expanded from aiding diagnosis to monitoring treatment responses, prognostic assessment, and the development of individualized treatment strategies. This review systematically summarizes biomarkers in the field of spinal muscular atrophy, including physiological indicators, functional assessments, imaging features, and molecular markers, which are derived from the analysis of different tissues from human patients and animal models.
View Article and Find Full Text PDF(Oestridae: Gasterophilinae) is an obligate parasite of the alimentary tract of the Asian elephant, causing gastric myiasis. Current knowledge of its first instar larval morphology has been limited to observations under light microscopy, significantly constraining our understanding of morphological evolution within the genus and the broader subfamily Gasterophilinae. In this study, we provided ultrastructural and three-dimensional characterizations of using scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM) based on newly hatched first instar larvae.
View Article and Find Full Text PDFBiochem Pharmacol
July 2025
Breast cancer liver metastasis presents a significant clinical challenge, requiring a deeper understanding of its underlying mechanisms. In this study, we explored the role of serum metabolites and gut microbiota in breast cancer liver metastasis, with a particular focus on the effects of glycochenodeoxycholic acid sodium salt (GCDC). Serum metabolites were analyzed using liquid chromatography-mass spectrometry (LC-MS), while gut microbiota composition was assessed through 16S rDNA sequencing of stool samples.
View Article and Find Full Text PDFBackground: Petrovinema skrjabini (Nematoda: Strongylidae, Cyathostominae) is a parasitic nematode colonizing the cecum and colon of equids. Like other cyathostomins, its larvae (L3) invade the intestinal mucosa, forming encysted nodules that may remain dormant for years. Mass larval emergence triggers larval cyathostominosis-a severe syndrome characterized by hemorrhagic typhlocolitis and diarrhea, with mortality rates exceeding 50%.
View Article and Find Full Text PDFThis study aimed to assess the clinical management of warfarin therapy in Western China by investigating: the rate of international normalized ratio (INR) target achievement and its influencing factors, and the incidence and risk factors for hemorrhagic complications. The primary goal was to identify high-risk patient populations requiring intensified monitoring in this resource-limited region with distinct demographic challenges including multi-ethnic populations and limited healthcare access. We conducted a retrospective cohort analysis of 154 consecutive inpatients prescribed warfarin at a tertiary care center in Western China.
View Article and Find Full Text PDFClin Transl Gastroenterol
July 2025
Introduction: Chronic liver inflammation leads to fibrosis, cirrhosis, and hepatocellular carcinoma. Serum alanine aminotransferase is the most widely used indicator of liver inflammatory injury, but it does not accurately reflect the extent of chronic liver inflammation. The role of exosomes in chronic liver inflammation and fibrosis has gained significant interest.
View Article and Find Full Text PDFFowl adenovirus serotype 4 (FAdV-4) is a non-enveloped double-stranded DNA virus with a 43-45 kb genome. This characteristic makes it a promising viral vector for expressing other antigens in developing multi-valent or multi-series vaccines in the poultry industry. To create an easy-to-use reverse genetics system for manipulating FAdV-4 genomic DNA, a full-length infectious clone of FAdV-4 was constructed using lambda Red-mediated recombination in Escherichia coli DH10B.
View Article and Find Full Text PDFDiabetic kidney disease (DKD) is one of the most severe complications of diabetes mellitus, with limited effective therapeutic interventions. Alternate-day fasting (ADF) shows potential in treating DKD, though its mechanisms are not fully understood. In this study, BTBR ob/ob mice underwent 12 weeks of ADF, and high-resolution untargeted metabolomics were performed to uncover the underlying mechanisms.
View Article and Find Full Text PDFBackground: Immune checkpoint inhibitors (ICIs) are emerging promising agents for the treatment of patients with esophageal squamous cell carcinoma (ESCC), however, there are only a small proportion respond to ICI therapy. Therefore, selecting candidate patients who will benefit the most from these drugs is critical. However, validated biomarkers for predicting immunotherapy response and overall survival are lacking.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Potential applications of microwave energy, a developed form of clean energy, are diverse and extensive. To expand the applications of microwave heating in the metallurgical field, it is essential to obtain the permittivity of ores throughout the heating process. This paper presents the design of a 2.
View Article and Find Full Text PDFRose () petals are rich in diverse secondary metabolites, which have important physiological functions as well as great economic values. Currently, it remains unclear how saline and/or alkaline stress(es) influence the accumulation of secondary metabolites in rose. In this study, we analyzed the transcriptome and metabolite profiles of rose petals under aline-alkali stress and uncovered the induction mechanism underlying major metabolites.
View Article and Find Full Text PDFFor Res (Fayettev)
April 2024
Plant Commun
January 2025
To investigate the epidemiological characteristics of anemia of varying severity among women of reproductive age, we conducted a nationwide, cross-sectional study between January 1, 2019 and December 31, 2019, including 4 184 547 nonpregnant women aged 18-49 years from all 31 provinces in the mainland of China. Anemia was defined as having hemoglobin concentration < 120.0 g/L and categorized as mild, moderate, and severe.
View Article and Find Full Text PDFRecent studies on oestroidean Diptera (Brachycera) are providing a comprehensive and nuanced understanding of the evolutionary history of this remarkably diverse clade of holometabolous insects. The Oestroidea, which includes formidable pests such as various blowflies, botflies, and flesh flies that infest livestock, pets and humans, are mostly composed of beneficial species that act as scavengers or parasitoids on various pest insects. In our research, we used genomic methods to elucidate the phylogenetic position of Nesodexia corsicana Villeneuve, 1911 (Diptera: Calliphoridae), a mysterious oestroid species endemic to Corsica and characterized by distinctive morphological features that have puzzled taxonomists for years.
View Article and Find Full Text PDFBackground: Acer truncatum Bunge is an economic, ecological, oil, and medicinal tree, and its kernel oil is rich in nervonic acid. It is crucial to explore the transcriptional expression patterns of genes affecting fatty acid synthesis to improve the quality of Acer truncatum oil.
Results: This study used the seeds from high fatty acid strain YQC and those from low fatty acid strain Y38 as the test materials.
Imeta
April 2024
In digital holographic microscopy (DHM), achieving large field of view (FOV) imaging while maintaining high resolution is critical for quantitative phase measurements of biological cell tissues and micro-nano structures. We present a quantitative phase image stitching guided by reconstructed intensity images in one-shot double FOV multiplexed DHM. Double FOVs are recorded simultaneously through frequency division multiplexing; intensity feature pairs are accurately extracted by multi-algorithm fusion; aberrations and non-common baselines are effectively corrected by preprocessing.
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