Nanomaterials (Basel)
July 2025
Epitaxial growth of β-GaO nanowires on silicon substrates was realized by the low-pressure chemical vapor deposition (LPCVD) method. The as-grown Si/GaO heterojunctions were employed in the Underwater DUV detection. It is found that the carrier type as well as the carrier concentration of the silicon substrate significantly affect the performance of the Si/GaO heterojunction.
View Article and Find Full Text PDFOrganic molecules with reversible redox are emerging as promising materials for low power memristors. However, the structure-property relationship between the molecular structure and threshold voltage is not clear; achieving low threshold voltage memristors is still a challenge. To address this issue, a series of conjugated Blatter radicals with tunable redox were designed and synthesized by varying the functional groups.
View Article and Find Full Text PDFBackground: Carbapenemase-producing Citrobacter (CPC) species have recently been recognised as emerging pathogens associated with nosocomial infections in humans. The increased rate of Citrobacter freundii infections is a public health concern and there is a paucity of genomic data regarding its global transmission dynamics. We aimed to characterise the genetic features of CPC species, and their associated carbapenemase-encoding plasmids, obtained from hospitalised patients in China and from publicly available global data, with a particular focus on high-risk clones.
View Article and Find Full Text PDFACS Appl Mater Interfaces
July 2025
Phototransistors based on GaO are widely used in civil or military applications as a three-terminal device with solar-blind characteristics. This study constructed amorphous gallium oxide (a-GaO) thin film transistor (TFT)-based solar-blind photodetectors and explored the effect of the oxygen partial pressure on films and devices. It had been found that there is a strong correlation between oxygen partial pressure and photodetector properties.
View Article and Find Full Text PDFThe limited bioavailability of free phytosterols restricts their clinical application in managing hypercholesterolemia. This study aimed to develop phytosterol nanoparticles (PNs) to enhance bioactivity and investigate their cholesterol-lowering efficacy and underlying mechanisms in vivo. Phytosterol nanoparticles (PNs) (93.
View Article and Find Full Text PDFAntimicrob Agents Chemother
August 2025
Tigecycline is a last resort antibiotic that is used to treat serious infections; however, some bacteria have developed tigecycline resistance by producing a tigecycline-inactivating enzyme or tigecycline resistance efflux pump, encoded by (X) and genes, respectively. Tons of seafood are consumed annually in China; however, whether seafood harbors tigecycline-resistant bacteria is not known. In this study, we isolated various tigecycline-resistant bacteria from retail seafood; among these, was the predominant tigecycline-resistant genus (33/76, 43.
View Article and Find Full Text PDFThe retroperitoneal approach for RAPN minimizes interference with intraperitoneal organs but is constrained by a restricted operating space. The single-port (SP) robotic platform excels in navigating tight anatomical environments compared to the multi-port (MP) robotic system. However, there are not many studies that compare the results of surgery using these two platforms when the retroperitoneal approach is used.
View Article and Find Full Text PDFBackground: The SLC2A1 gene plays a vital role in brain energy metabolism. SLC2A1 variants have been reported to be associated with early-onset refractory seizures. This study aims to explore the association between the SLC2A1 gene and late-onset epilepsy.
View Article and Find Full Text PDFUnlabelled: Plant height is a crucial agronomic trait in wheat, regulated by multiple genes, and significantly influences plant architecture and wheat yield. In this study, a novel dwarf mutant, designated as , was developed and characterized through the treatment of seeds from the common wheat cultivar Jinmai47 with ethyl methanesulfonate (EMS). Microscopic analysis revealed that the dwarf phenotype was attributed to a reduction in the longitudinal cell size of the stem.
View Article and Find Full Text PDFPlant-derived condensed tannins (CT) exhibit strong bioactivity of antioxidant, immunostimulation and intestinal protection, but with little clues of the mechanism of action. Since CT are consist of catechins (CAs) monomers, e.g.
View Article and Find Full Text PDFUnderstanding the interaction of biotic and abiotic factors on ecosystem function is crucial for freshwater ecosystem management, However, the influence of nutrient enrichment, fungicide presence, and detritivore identity on leaf litter decomposition and associated fungal communities remains poorly understood. We conducted a microcosm experiment to examine: 1) the individual and combined effects of nutrient enrichment and a common fungicide on leaf litter decomposition and fungal communities; and 2) how two types of detritivore invertebrates (scrapers vs. shredders) influence these effects.
View Article and Find Full Text PDFThe rapid growth of microbiome research has generated an unprecedented amount of multi-omics data, presenting challenges in data analysis and visualization. To address these issues, we present MicrobiomeStatPlots, a comprehensive platform offering streamlined, reproducible tools for microbiome data analysis and visualization. This platform integrates essential bioinformatics workflows with multi-omics pipelines and provides 82 distinct visualization cases for interpreting microbiome datasets.
View Article and Find Full Text PDFZhonghua Wei Zhong Bing Ji Jiu Yi Xue
January 2025
Objective: To analyze the clinical characteristics of elderly patients with sepsis, identify the key factors affecting their clinical outcomes, construct a death risk assessment scale for elderly patients with sepsis, and evaluate its predictive value.
Methods: A retrospective case-control study was conducted. The clinical data of sepsis patients admitted to intensive care unit (ICU) of the First Affiliated Hospital of Wenzhou Medical University from September 2021 to September 2023 were collected, including basic information, clinical characteristics, and clinical outcomes.
Objectives: In this study, we aimed to explore the association between the choice of empirical antibiotic therapy and outcomes in ED patients with sepsis.
Methods: Patients admitted to ED with sepsis were identified from a single center in the United States, and the data is stored in the MIMIC-IV-ED database. Propensity score matched model was used to match patients receiving empirical mono or combination antibiotic therapy.
Despite improved sensitivity of iontronic pressure sensors with microstructures, structural compressibility and stability issues hinder achieving exceptional sensitivity across a wide pressure range. Herein, the interplay between ion concentration, mechanical properties, structural geometry, and aspect ratio (AR) on the sensitivity of lithium bis(trifluoromethanesulfonyl) imide/thermoplastic polyurethane (LiTFSI/TPU) ionogel is delved into. The results indicate that cones exhibit superior compressibility compared to pyramids and hemispheres, manifesting in an enhanced sensitivity toward the LiTFSI/TPU ionogel.
View Article and Find Full Text PDFThe Sc2.0 global consortium to design and construct a synthetic genome based on the Saccharomyces cerevisiae genome commenced in 2006, comprising 16 synthetic chromosomes and a new-to-nature tRNA neochromosome. In this paper we describe assembly and debugging of the 902,994-bp synthetic Saccharomyces cerevisiae chromosome synXVI of the Sc2.
View Article and Find Full Text PDFBiomed Mater
February 2025
The articular cartilage is characterized by its gradient hierarchical structure, which exhibits excellent lubrication and robust load-bearing properties. However, its inherent difficulty in self-repair after damage presents numerous formidable challenges for cartilage repair. Inspired by the unique structure of articular cartilage, a biomimetic bilayer hydrogel composed of PAM (polyacrylamide) and PAM/SA (sodium alginate) is prepared using a two-stepswelling method.
View Article and Find Full Text PDFThis study examined the diversity and responses of intestinal microbiota in hybrid grouper ( ♀ × ♂) fed diets with varying levels of fishmeal replaced by black soldier fly larvae (BSFL). The 10% BSFL substitution (BSFL10) group showed the highest levels of trypsin and amylase. Substituting fishmeal with 30% and 50% BSFL weakened the intestinal wall, resulting in vacuoles, sparse striatal boundaries, and fewer villi.
View Article and Find Full Text PDFImeta
December 2024
Sheng Wu Gong Cheng Xue Bao
December 2024
To clarify the genetic diversity and structure of the nucleus population of F1-generation , this study utilized 15 pairs of highly polymorphic microsatellite primers to analyze the simple sequence repeat (SSR) markers and genetic diversity in 15 full-sib families of . . A total of 112 alleles () and 60.
View Article and Find Full Text PDFNanophotonics
June 2024
Exciton-polariton condensates, due to their nonlinear and coherent characteristics, have been employed to construct spin Hamiltonian lattices for potentially studying spin glass, critical dephasing, and even solving optimization problems. Here, we report the room-temperature polariton condensation and polaritonic soft-spin XY Hamiltonian lattices in an organic-inorganic halide perovskite microcavity. This is achieved through the direct integration of high-quality single-crystal samples within the cavity.
View Article and Find Full Text PDFNat Commun
November 2024
Materials (Basel)
November 2024
In this study, the size of molten pool and the porosity of parts under different processing parameters are studied using numerical simulation. According to the results, the appropriate processing parameters were selected to simulate the temperature and residual stress distribution during the forming process of body-centered cube (BCC), face-centered cube (FCC) and rhombic dodecahedron (Dode) lattice structures. In addition, three lattice structures were fabricated via selective laser melting (SLM) technology, and quasi-static compression experiments were carried out to study their mechanical properties.
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