Moisture Microenvironment-Regulating Electro spun Membranes for Extending Litchi Shelf Life.

To address post-harvest issues of litchi, including browning, water loss, and nutrient degradation, a moisture microenvironment-regulating electro spun membrane was prepared by incorporating hydrophobic carnauba wax (CW)@nano silica (SiO) composite powder into a polyethylene terephthalate (PET) matrix via electro spinning. The dynamic water penetration equilibrium was evaluated by monitoring the water vapor absorption of the electrospun membrane within 12 h, while the effects of CW@SiO on the micro-structure, mechanical properties, hydrophobicity, and thermal stability were investigated. Results showed that the tensile strength of the PET-2.

Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway.

Background: Colitis, a inflammatory disorder of the colon, causes significant morbidity and declines quality of life. Despite treatment advancements, effective therapies remain limited. Wuda Granules (WDG), a traditional medicine formula, is clinically used for intestinal obstruction and gastrointestinal recovery through its anti-inflammatory effects.

Identification of Shared Genetic Loci Associated With Inflammatory Bowel Disease, Ischemic Heart Disease, and Atrial Fibrillation and Flutter.

The occurrence of ischemic heart disease (IHD), atrial fibrillation, and flutter demonstrates certain associations with inflammatory bowel disease (IBD), warranting further exploration at the genetic architecture level. This study focused on genome-wide association study (GWAS) data of IHD, atrial fibrillation and flutter, and IBD, analyzing from two dimensions: genetic correlation and shared locus identification. Initially, linkage disequilibrium score regression and genetic covariance analyzer were utilized to assess the overall genetic correlations.

Astragalus polysaccharide alleviates IL-13-induced oxidative stress injury in nasal epithelial cells by inhibiting WTAP-mediated FBXW7 mA modification.

Background: Allergic rhinitis (AR) a common and complicated upper airway disease mediated by specific IgE antibodies. Our study aims to explore the pharmacological effects of astragalus polysaccharide (APS) on AR and elucidate the mechanisms involved.

Methods: RT-qPCR and Western blotting were used to analyze mRNA and protein expression.

Porous organic polymers assisted aptamer signal amplification for enhanced photoeletrochemical detection of MUC1.

Mucin1 (MUC1) is an extensively glycosylated transmembrane protein that is widely distributed and overexpressed on the surface of cancer cells, playing an important role in tumor occurrence and metastasis. Therefore, highly sensitive detection of MUC1 is of great significance for early diagnosis, treatment monitoring, and prognosis of cancer. Here, an ultra-sensitive photoelectrochemical (PEC) sensing platform was developed based on an aptamer amplification strategy for highly selective and sensitive detection of MUC1 overexpressed in serum and on cancer cell surfaces.

Highly-efficient Eu-activated SrSiOCl cyan-emitting phosphors with zero-thermal quenching luminescence for versatile applications.

To settle the problem of phosphors with unsatisfactory luminescence efficiency and serious thermal quenching, Eu-activated SrSiOCl cyan-emitting phosphors were designed. Excited at 387 nm, a dazzling cyan emission located at 492 nm is observed in the resultant phosphors and its maximum intensity is obtained when the Eu content is 4 mol%. Moreover, the zero-thermal quenching luminescence, even when the temperature is 503 K, the integrated emission intensity still maintains 106% of its starting value at 303 K, is realized in resultant phosphors because of the efficient energy transfer from defect levels to Eu, which is confirmed by the thermoluminescence spectrum.

Development of functional hydroxyethyl cellulose-based composite films for food packaging applications.

Cellulose-based functional composite films can be a good substitute for conventional plastic packaging to ensure food safety. In this study, the semi-transparent, mechanical strengthened, UV-shielding, antibacterial and biocompatible films were developed from hydroxyethyl cellulose Polyvinyl alcohol (PVA) and ε-polylysine (ε-PL) were respectively used as reinforcing agent and antibacterial agent, and chemical cross-linking among these three components were constructed using epichlorohydrin The maximum tensile strength and elongation at break were 95.9 ± 4.

POSS and imidazolium-constructed ionic porous hypercrosslinked polymers with multiple active sites for synergistic catalytic CO transformation.

In this work, we reported a facile one-pot approach to construct polyhedral oligomeric silsesquioxane (POSS) and imidazolium-based ionic porous hypercrosslinked polymers (denoted as iPHCPs) with multiple active sites towards efficient catalytic conversion of carbon dioxide (CO) to high value-added cyclic carbonates. The targeted iPHCPs were synthesized from a rigid molecular building block octavinylsilsesquioxane (VPOSS) and a newly-designed phenyl-based imidazolium ionic crosslinker through the AlCl-catalyzed Friedel-Crafts reaction. The desired multiple active sites come from the mixed anions including free Cl and Br anions, and in situ formed Lewis acidic metal-halogen complex anions [AlClBr] within imidazolium moieties and POSS-derived Si-OH groups during the synthetic process.

CO-free hydrogen production via ammonia decomposition over mesoporous Co/AlO catalysts with highly dispersed Co species synthesized by a facile method.

Transition metals have been considered as potential catalysts for ammonia decomposition to produce CO-free hydrogen for fuel cells. However, the facile synthesis of transition metal catalysts with small size active species, high porosity and good structural stability is still a challenge in catalytic NH decomposition. Herein, mesoporous Co/AlO catalysts with various cobalt contents were synthesized by a facile modified sol-gel method.

The Phase Relations of the Co-Ni-In Ternary System at 673 K and 873 K and Magnetic Properties of Their Compounds.

The phase relationships of the ternary Co-Ni-In system at 673 K and 873 K were investigated by means of powder X-ray diffraction, scanning electron microscopy equipped with energy dispersive spectroscopy, and optical microscopy. Though CoIn does not exist at 873 K, the ternary solid solution CoNiIn exists at both 673 K and 873 K with different composition ranges. The Rietveld refinements were carried out to investigate the crystal structure of CoNiIn (x = 0.

Metalated-bipyridine-based porous hybrid polymers with POSS-derived Si-OH groups for synergistic catalytic CO fixation.

Herein, we construct a new series of N-heterocyclic ligand bipyridine-based porous hybrid polymers (denoted Bpy-PHPs) from the Heck reaction of a rigid building unit octavinylsilsesquioxane (VPOSS) and 5,5'-dibromo-2,2'-bipyridine. Surprisingly, the typical sample Bpy-PHP-4 was found to be a metal-/halogen-free heterogeneous catalyst in the cycloaddition reaction of CO2 with a few epoxides under atmospheric pressure. After coordination with ZnBr2, the resultant ZnBr2@Bpy-PHP-4 afforded largely enhanced heterogeneous catalytic activities upon the conversion of carbon dioxide (CO2) and various epoxides into cyclic carbonates without using any co-catalysts under mild conditions.

Antinociceptive Effects of Shenling Baizhu through PI3K-Akt-mTOR Signaling Pathway in a Mouse Model of Bone Metastasis with Small-Cell Lung Cancer.

Shenling Baizhu additive powder (SLBZ-AP), a formulation of a variety of natural medicinal plants, has clinical efficacy in treating cancers in previous studies. We explored the effect of SLBZ-AP in bone metastasis of lung cancer (BMLC) mice, and the possible mechanism involved was further investigated in the present study. Mice model of BMLC was made and treated with SLBZ-AP.

An easy way to identify high performing covalent organic frameworks for hydrogen storage.

The complexity of secondary building units (SBUs), an indicator that can not only be calculated but also visually estimated, is proposed as a highly indicative predictor of hydrogen storage performance. With optimal pore sizes and void fractions, selecting COFs consisting of simple SBUs greatly improves the probability of top-performing COFs towards the ultimate DOE hydrogen storage target, as an easy principle for experimentalists to select hydrogen adsorbents.

Two-in-one: construction of hydroxyl and imidazolium-bifunctionalized ionic networks in one-pot toward synergistic catalytic CO fixation.

A succinct strategy was demonstrated for constructing a hydroxyl group and imidazolium-bifunctionalized ionic network via a one-pot quaternization. Key to success lies in the rational design of multi-imidazole precursor and hydroxyl-containing counterpart. Unique properties of the resultant ionic network render its high catalytic efficiency toward CO2 fixation under ambient conditions.

Facile synthesis of crystalline viologen-based porous ionic polymers with hydrogen-bonded water for efficient catalytic CO fixation under ambient conditions.

In this work, we report a series of crystalline viologen-based porous ionic polymers (denoted VIP-X, X = Cl or Br), that have formed dicationic viologens paired with halogen anions and intrinsic hydrogen-bonded water molecules, towards metal-free heterogeneous catalytic conversion of carbon dioxide (CO) under mild conditions. The targeted VIP-X materials were facilely constructed the Menshutkin reaction of 4,4'-bipyridine with 4,4'-bis(bromomethyl)biphenyl (BCBMP) or 4,4'-bis(chloromethyl)biphenyl (BBMBP) monomers. Their crystalline and porous structures, morphological features and chemical structures and compositions were fully characterized by various advanced techniques.

[Effects of socioeconomic factors on urban plant diversity of residential areas in Shanghai, China].

Residential area, usually consisting of buildings and vegetation, is one of the dominant land use types and an important kind of habitat in the urban area. Therefore, it plays an important role in urban biodiversity conservation. Previous studies found that plant diversity abroad in urban residential areas was influenced by socioeconomic factors.

Plasmonic-3D photonic crystals microchip for surface enhanced Raman spectroscopy.

Plasmonic-dielectic hybrid substrates of Ag-islands on three-dimensional photonic crystals are fabricated through magnetron sputtering of silver onto hydrophobized silica photonic crystals, free from etching process. Without typical "hot-spots" such as nanogaps, significant Raman enhancements can be achieved, attributed to the enhanced electromagnetic field and scattering of the plasmonic nanoparticles as well as the enhanced light-matter interaction by the slow photon effects. The detection limit for adenine by the hybrid substrates reaches nM level, with a calculated enhancement factor of 1.

Ku86 alleviates human umbilical vein endothelial cellular apoptosis and senescence induced by a low dose of ionizing radiation.

Objective: The aim of this study was to observe the effect of Ku86 on cellular senescence and apoptosis induced by various doses of ionizing radiation in human umbilical vein endothelial cells (HUVECs).

Methods: Senescence-associated β-galactosidase activity was detected to evaluate cell senescence. Apoptosis was determined by flow cytometry and a caspase enzyme determination kit.

Constructing POSS and viologen-linked porous cationic frameworks induced by the Zincke reaction for efficient CO capture and conversion.

POSS and viologen-linked porous cationic frameworks (V-PCIF-X, X = Cl, Br) are constructed via the Zincke reaction between octa(aminophenyl)silsesquioxane and viologen linkers. The typical V-PCIF-Br has a high surface area with abundant ionic sites, micro-/mesopores and Si-OH groups, serving as an efficient porous adsorbent and metal-free catalyst for simultaneous CO2 capture and conversion.

Does magnification of SEM image influence quantification of particulate matters deposited on vegetation foliage.

The metrics used to quantify the particles on the leaf surface can serve as indicators for the quality of the atmospheric environment and is employed to evaluate the ecosystem services that plants can provide. Magnification of an SEM image may affect the recognition of particles in various aspects, yet little research has examined the impact. In this study, images were obtained at magnifications of 500×, 1000×, 2000×, and 5000× for a widely planted vegetation fence species in Beijing: Euonymus japonicas.

A factor analysis of landscape metrics of particles deposited on leaf surface.

Particulate matter in the airborne environment is one of the top environmental concerns, as well as reasons of deaths and diverse diseases. Urban green infrastructure can improve the air quality by mitigating particulate matters from airborne environment and provide high spatial monitoring of particles by means of leaf particles as indicators. Three common species in Beijing (ailanthus, ash, and willow) were chosen to represent three different leaf characteristics.

P-Doped carbons derived from cellulose as highly efficient metal-free catalysts for aerobic oxidation of benzyl alcohol in water under an air atmosphere.

P-Doped carbons, prepared by carbonizing phosphoric acid-treated cellulose, exhibit high catalytic activity in metal-free aerobic oxidation of benzyl alcohol to benzaldehyde (99.7% yield) in water under air. A high turnover frequency is obtained due to the doped P-species of C3PO, identified via experiments and DFT calculations.

Cross-Linked Graphitic Carbon Nitride with Photonic Crystal Structure for Efficient Visible-Light-Driven Photocatalysis.

Highly cross-linked graphitic carbon nitride has been prepared by a thermal copolymerization of dicyanodiamide with tetramethylammonium salts. The cross-linking can be evidenced by (i) increased C/N ratio without new carbon species, (ii) decreased specific surface area, and (iii) Tyndall effect after dissolution in concentrated sulfuric acid. The cross-linked graphitic carbon nitride with photonic crystal structure has highly efficient photocatalytic activity for water splitting under visible light due to the synergistic enhancement by the greatly suppressed photoluminescence, red-shifted absorption edges, strong inner reflections, and effective PCs stop band overlaps.

Asiatic acid enhances survival of human AC16 cardiomyocytes under hypoxia by upregulating miR-1290.

Asiatic acid (AA) could attenuate ischemia/reperfusion induced myocardial apoptosis through upregulating the Akt/GSK-3β/HIF-1α pathway. HIF-3α is a negative regulator of HIF-1α, whose mRNA is a potential target of miR-1290. AA could upregulate miR-1290 in non-small-cell lung cancer A549 cells.