Spectro-Electrochemical Insights into Electrocatalytic CO Reduction in Acidic Media through Model Catalyst Design.

Electrocatalytic CO reduction (eCOR) under acidic conditions is the game changer of resourceful CO utilization owing to the alleviated carbon loss but faces severe competition from the hydrogen evolution reaction (HER) that greatly curtails the electric current efficiency. Leveraging the eCOR side of the teeterboard calls for a fundamental understanding of the triphasic electrode process involving a complex arrangement of electric double layers (EDLs). Herein, a series of model catalysts with tailored cavernous parameters are fabricated to geometrically and spectroscopically decipher the competing HER and eCOR processes that engage different proton sources.

Utilisation of AI-driven chatbots for perioperative health information seeking: a descriptive qualitative study of orthopaedic patients and family members.

Objective: This study aimed to explore orthopaedic patients' and families' experiences with artificial intelligence (AI)-driven chatbots for perioperative health information, focusing on usability, effectiveness and perceptions.

Design: A descriptive qualitative design was employed.

Setting: This study was conducted at a regional care centre for orthopaedics.

Stabilizing Reticular Frameworks and Modulating Interfacial Water via Conductive Polymer Encapsulation in Metal-Organic Frameworks Electrocatalysts for Efficient Methane Production.

The electrochemical reduction of CO to CH offers a promising pathway for renewable energy storage, yet remains limited by sluggish kinetics, poor catalyst stability, and competing hydrogen evolution reactions (HER). Herein, a host-guest strategy is reported for engineering metal-organic frameworks (MOFs) through the encapsulation of conductive polymers to stabilize reticular skeletons and regulate interfacial water for efficient CO-to-CH conversion. Specifically, polypyrrole (PPy) and polyaniline (PANI) are confined within Cu-anchored UiO-67 frameworks, resulting in hybrid catalysts-PPy@Cu-UiO-67 and PANI@Cu-UiO-67-with preserved crystallinity and enhanced electronic conductivity.

The impact of halo-pelvic traction on deformity correction and bone mineral density in patients with severe spine deformity.

Background: Severe spinal deformities require surgical intervention, with preoperative traction commonly used to improve spinal flexibility and surgical safety. However, the impact of traction on bone mineral density (BMD) and its relationship with correction outcomes remains poorly understood.

Methods: This retrospective study analyzed patients with severe spinal deformities who underwent halo-pelvic traction before surgical correction.

Study on the combustion characteristics of NH and hydrochar mixture using ReaxFF MD: Oxygen equivalence ratio, ammonia co-combustion ratio, and combustion environment.

Co-combustion of NH (ammonia) and hydrochar is a promising strategy to reduce fossil fuel usage and CO emissions. In this study, reactive molecular dynamics simulations (ReaxFF MD) were performed to investigate the effects of oxygen equivalence ratio (λ), ammonia co-combustion ratio, and combustion atmosphere on the combustion characteristics of the NH/hydrochar mixture. Firstly, Increasing the oxygen equivalence ratio from 0.

Multistage correction of severe kyphoscoliosis and pulmonary compromise in adults through combined halo-pelvic traction and posterior spinal techniques.

Patients with kyphoscoliosis can present with a variety of chief complaints, including axial back pain, concerns about cosmesis, progressively worsening respiratory function, and even neurological deficits. Correction of severe adult kyphoscoliosis remains challenging due to the severity of the deformity and poor cardiopulmonary function. Direct one-stage corrective surgery can lead to enormous complications and unsatisfactory outcomes when dealing with patients with severe kyphoscoliosis.

Engineering catalyst-support interactions in cobalt phthalocyanine for enhanced electrocatalytic CO reduction: the role of graphene-skinned AlO.

Electrocatalytic CO reduction (eCOR) driven by renewable electricity holds great promise to mitigate anthropogenic CO emissions. In this study, we engineer cobalt phthalocyanine (CoPc) supported on graphene-skinned AlO nanosheets (CoPc/AlO@C) to enhance CO-to-CO conversion. The strong π-π stacking between the CoPc macrocycle and interlayer graphene, coupled with electronic repulsion between the Co center and AlO, induces a structural distortion in CoPc, raising the energy level of the d orbital.

Treatment for paraplegia due to severe kyphoscoliosis associated with neurofibromatosis type 1 via halo-pelvic traction: a case report.

Background: A sharply angular thoracic deformity, commonly seen in dystrophic scoliosis associated with neurofibromatosis type 1, can compress the spinal cord and potentially cause neurological impairment. However, managing paraplegia due to severe kyphoscoliosis associated with neurofibromatosis type 1, coupled with low body mass index and extremely severe kyphoscoliosis, presents a significant challenge.

Case Presentation: A 13-year-old girl of Mongolian ethnicity with severe dystrophic kyphoscoliosis associated with neurofibromatosis type 1 presented with paraplegia and dyspnea.

NDRG1 and its family members: More than just metastasis suppressor proteins and targets of thiosemicarbazones.

N-Myc downstream regulated gene-1 (NDRG1) and the other three members of this family (NDRG2, 3, and 4) play various functional roles in the cellular stress response, differentiation, migration, and development. These proteins are involved in regulating key signaling proteins and pathways that are often dysregulated in cancer, such as EGFR, PI3K/AKT, c-Met, and the Wnt pathway. NDRG1 is the primary, well-examined member of the NDRG family and is generally characterized as a metastasis suppressor that inhibits the first step in metastasis, the epithelial-mesenchymal transition.

N-Confused Porphyrin as a Highly Active Ligand Scaffold for Molecular Catalysts of CO Reduction.

Key to CO reduction transformation is the development of catalysts that efficiently activate inert CO molecules, enabling rapid reaction kinetics with minimal energy inputs. In this study, we introduce N-confused porphyrin (NCP) as a highly active ligand scaffold for transition metal-based catalysts in CO reduction reactions. By breaking the D symmetry inherent in conventional porphyrin structures, NCP promotes enhanced electron delocalization around corresponding metal complex, improving the catalytic efficiency.

Radiologic and clinical outcomes of combining pedicle subtraction osteotomy and Smith-Peterson osteotomy in correcting severe ankylosing spondylitis kyphosis.

The aim of this study was to explore the validity and safety of the combination of one-level pedicle subtraction osteotomy (PSO) and one-level Smith-Petersen osteotomy (SPO) in correcting severe ankylosing spondylitis kyphosis. Twenty-five AS patients undergoing one-level PSO and one-level SPO with a minimum of 2-year follow-up were included. Radiographical analyses included T5-T12 kyphosis (TK), L1-S1 lordosis (LL), global kyphosis (GK), osteotomized vertebral angle (OVA), sagittal vertical axis (SVA) and pelvic parameters.

Anesthetic management of folders with severe kyphosis in ankylosing spondylitis: a single-center retrospective case series study.

Background: Ankylosing spondylitis (AS) is a progressive inflammatory disease causing severe kyphosis, which complicates surgical management and increases complication risks. This study aims to analyze the characteristics of severe kyphosis in AS and explore methods to optimize perioperative management and reduce complications.

Methods: We conducted a retrospective analysis of clinical data from five patients with severe kyphosis in AS who underwent surgery between October 2017 and February 2022.

Metal-organic double layer to stabilize selective multi-carbon electrosynthesis.

Stable operation of the gas diffusion electrodes is key for industrial-scale electrochemical CO reduction (eCOR). To enhance the electrolytic stability, we shield the Cu-coated gas diffusion electrode with a polycationic sheath via electrospinning and propose a Metal-Organic Double Layer (MODL) scheme to depict the triphasic interface. The as-fabricated electrode exhibits a high multi-carbon Faradaic efficiency of 91.

Enhancing the blast resistance of an elite thermo-sensitive genic male sterile line (TGMS) Longke638S and its derived hybrid varieties by incorporating gene.

Unlabelled: Rice blast, caused by the fungal pathogen , is one of the most destructive diseases of rice worldwide. The utilization of host resistance () genes in rice breeding program is considered as the most economical, effective, environment-friendly strategy for rice blast control. The gene , shows high, broad-spectrum and durable resistance to rice blast.

Integration of longitudinal load-bearing tissue MRI radiomics and neural network to predict knee osteoarthritis incidence.

Background: Load-bearing structural degradation is crucial in knee osteoarthritis (KOA) progression, yet limited prediction models use load-bearing tissue radiomics for radiographic (structural) KOA incident.

Purpose: We aim to develop and test a Load-Bearing Tissue plus Clinical variable Radiomic Model (LBTC-RM) to predict radiographic KOA incidents.

Study Design: Risk prediction study.

Highly dispersed antenna-single-atom-reactor on metal-organic frameworks support for efficient photocatalytic CO reduction.

We describe the precise nano-assembly of an antenna-single-atom-reactor based on a UiO-66-(SH) metal-organic framework support. We lock Ag plasmon nanoparticles in the thio-functionalized pore channels Ag-S interaction, and anchor Cu single atoms on the oxygen-bridged Zr cluster anodes based on Cu-O bonds, leading to highly dispersed AgCu@UiOS with exceptional catalytic activity for the photocatalytic reduction of CO.

Decoding the synergistic mechanisms of functional microbial agents on the microecology and metabolic function in medium-high temperature starter for enhancing aromatic flavor.

Utilizing functional has emerged as an effective strategy to enhance aromatic compounds in Chinese Baijiu. However, research on how functional microbial agents enhance aromatics-producing enzymes and maintain community homeostasis in functional remains limited. Herein, we reveal the mechanisms of functional microbial agents for enhancing aromatic compounds through reducing interspecies interactions and simplifying the ecological network to drive the aggregated distribution of lactic acid bacteria, and inducing a localized microecology comprised of , , , , , and , effectively boosting the expression of key enzymes for aromatic synthesis.

Machine learning-assisted aroma profile prediction in Jiang-flavor baijiu.

The complex flavor of Jiang-flavor Baijiu (JFB) arises from the interaction of hundreds of compounds at both physicochemical and sensory levels, making accurate perception challenging. Modern machine learning techniques offer precise and scientific approaches for predicting sensory attributes. This study applied flavoromics and sensory profiling to 27 representative JFB samples from main regions in China, integrating five machine learning algorithms to establish a novel strategy for predicting global aroma characteristics.

The risk factors for type ii respiratory failure in patients with severe scoliosis (less than 40-year old).

Objective: To investigate the risk factors for Type II respiratory failure associated with severe scoliosis in patients under 40 years of age.

Methods: Patients with severe scoliosis and pulmonary impairment treated in our hospital from January 2020 to December 2022 were recorded. We evaluated the spinal parameters in standing full spine X-rays, including the main thoracic curve, thoracic kyphosis, apical vertebrae, and distance between T1-T12.

DLGAP5 enhances bladder cancer chemoresistance by regulating glycolysis through MYC stabilization.

Bladder cancer (BLCA), one of the most lethal urological tumors, exhibits high rates of recurrence and chemoresistance, particularly to gemcitabine (GEM). Understanding the mechanisms of GEM resistance is crucial for improving therapeutic outcomes. Our study investigates the role of DLGAP5 in promoting GEM resistance through modulation of glycolysis and MYC protein stability in BLCA cells.

Arthroscopic surgery is not superior to conservative treatment in knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trails.

Background: Studies comparing the effectiveness of arthroscopic knee surgery and conservative treatment on knee osteoarthritis (OA) came up with inconsistent results. Systematic review on this topic still is still lacking. This systematic review and meta-analysis aimed to evaluate the effectiveness of arthroscopic knee surgery on knee OA, compared to conservative treatments.

Surgical Treatment Strategies for Ankylosing Spondylitis with "Folded Man" Deformity: A Single-Center Retrospective Case Series Study.

Objective: Ankylosing spondylitis (AS) combined with severe kyphotic deformity can cause the trunk to collapse, pressing tightly against the front of the thighs and forming a "folded man" deformity. The purpose of this article is to evaluate the effectiveness and safety of a treatment strategy for correcting the "folded man" deformity.

Methods: A retrospective study was conducted to analyze 12 AS patients with "folded man" deformity treated at our hospital with staged kyphosis correction in the lateral position, followed by total hip arthroplasty, from May 2018 to July 2021.

Well-Dispersed CsPbBr@TiO Heterostructure Nanocrystals from Asymmetric to Symmetric.

Metal halide perovskites (MHPs) have undergone rapid development in the fields of solar cells, light diodes, lasing, photodetectors, etc. However, the MHPs still face significant challenges, such as poor stability and heterocompositing with other functional materials at the single nanoparticle level. Herein, the successful synthesis of well-dispersed CsPbBr@TiO heterostructure nanocrystals (NCs) is reported, in which each heterostructure NC has only one CsPbBr with a precise anatase TiO coating ranging from asymmetric to symmetric.

Lithiophilic Polymers of High Conjugation and Mesoporosity Enable Lean and Dendrite-Free Lithium Anode.

Lithiated Cu current collectors with a lean Li supply have been extensively explored as prospective composite anodes for constructing lithium metal batteries (LMBs) but suffer from low Coulombic efficiencies (CE) and uncontrollable dendrite growth. Herein, two hexaazanonaphthalene (HATN)-based compounds comprising rich conjugated aromatic rings and redox-active C═N groups are synthesized and exploited to modify the Cu surface for mediating smooth Li plating/stripping. Compared to the HATN compound interlinked through flexible sigma bonds, the one conjugated through dual sp-carbon manifests a more rigid backbone, improved electric conductivity, and enhanced mesoporosity.