The global burden of aortic aneurysm attributable to hypertension from 1990 to 2021: Current trends and projections for 2050.

Background And Objectives: Hypertension is a major risk factor for aortic aneurysm (AA), but the global, regional, and national patterns of its related disease burden are not well studied. This study uses 2021 GBD data to examine trends in hypertension-related AA from 1990 to 2021, project future trends, and provide evidence for targeted prevention strategies.

Methods: This study extracted data on mortality, disability-adjusted life years (DALYs), age-standardized mortality rate (ASMR), and age-standardized DALY rate (ASDR) associated with AA attributable to hypertension from the 2021 GBD study.

Highly Accurate Attitude Estimation of Unmanned Aerial Vehicle Payloads Using Low-Cost MEMS.

Low-cost MEMS sensors are widely utilized in UAV platforms to address attitude estimation problems due to their compact size, low power consumption, and cost-effectiveness. Diverse UAV payloads pose new challenges for attitude estimation, such as magnetic interference environments and high dynamic environments. In this paper, we propose a hierarchical decoupled attitude estimation algorithm, termed HDAEA.

Alcohol Consumption Amount, Drinking Pattern, and the Trajectory of Multimorbidity: A Prospective Cohort Study.

This study aimed to investigate the impacts of both alcohol consumption amount and drinking pattern on the progression from healthy to first noncommunicable disease (FNCD), subsequently to multimorbidity, and ultimately to death. We conducted this analysis in the UK Biobank cohort (N = 284 744). Multimorbidity was defined as the coexistence of at least two noncommunicable diseases, including cancer, chronic respiratory disease, cardiovascular disease, and Type 2 diabetes.

Timing of unsaturated fat intake improves insulin sensitivity via the gut microbiota-bile acid axis: a randomized controlled trial.

The timing of dietary total fat intake influences glucose homeostasis, however, the impact of unsaturated fat (USFA) intake has yet to be explored. This 12-week, double-blind, randomized, controlled, 2 × 2 factorial-designed feeding trial investigated the effects of timing (lunch or dinner) and types of dietary USFA (high monounsaturated fat or polyunsaturated fat diet) intake on glucose metabolism in seventy prediabetes participants (mean age, 57 years). Sixty participants with completed fecal samples were included in the final analysis (n = 15 for each group).

Global burden of zinc deficiency among children under 5 years old from 1990 to 2020.

This study aims to estimate the global prevalence rate and disease burden of zinc deficiency from 1990 to 2020 in children under 5 years old. Using data from the WHO Global Database on Child Growth and Malnutrition and the Global Burden of Diseases, Injuries, and Risk Factors Study, we analysed the prevalence, disability-adjusted life years (DALYs), and deaths attributable to zinc deficiency by sex across 204 countries and territories worldwide from 1990 to 2020. Globally, the prevalence rate of zinc deficiency decreased from 40 to 22% from 1990 to 2020.

Endogenous Metabolites in Metabolic Diseases: Pathophysiologic Roles and Therapeutic Implications.

Breakthroughs in metabolomics technology have revealed the direct regulatory role of metabolites in physiology and disease. Recent data have highlighted the bioactive metabolites involved in the etiology and prevention and treatment of metabolic diseases such as obesity, nonalcoholic fatty liver disease, type 2 diabetes mellitus, and atherosclerosis. Numerous studies reveal that endogenous metabolites biosynthesized by host organisms or gut microflora regulate metabolic responses and disorders.

Quantity and meal timing of dietary cholesterol intake and cerebrovascular disease mortality.

: Recent guidelines have removed specific limitations of dietary cholesterol, which has raised considerable debate regarding the significance of cholesterol in the context of cerebrovascular disease (CBD). Furthermore, the relationship between the quantity and meal timing of dietary cholesterol intake and CBD mortality remains unclear. This study aims to explore the relationships between the quantity and meal timing of dietary cholesterol intake and CBD mortality among older adults using the U.

Circadian rest-activity rhythms and multimorbidity and mortality risks among menopausal women: a trajectory analysis of a UK Biobank cohort.

Background: Menopausal women undergo substantial physiological changes that can impact their overall health.

Objectives: We examined relationships between circadian rest-activity rhythms (CRARs) and multimorbidity progression in this population.

Methods: We used UK Biobank data, involving 10,138 participants, who were initially free of chronic conditions.

Association between dietary spermidine intake and cognitive performance in older adults: The U.S. National Health and Nutrition Examination Survey, 2011-2014.

Background: This study aimed to investigate the association between dietary spermidine (SPD) intake and cognitive performance in older adults.

Methods: We analyzed data from the 2011-2014 U.S.

Strong association between atherogenic index of plasma and obesity in college students.

Background: The issue of obesity is becoming more and more prominent. Understanding the metabolic profile of obese young adults and finding possible risk markers for early prediction and intervention is of great importance.

Methods: A total of 13,082 college students with an average age of 20 years were enrolled in this cross-sectional study.

Serum metabolic signatures and MetalnFF diagnostic score for mild and moderate metabolic dysfunction-associated steatotic liver disease.

To explore serum metabolic changes in metabolic dysfunction-associated steatotic liver disease (MASLD) with mild or moderate steatosis and develop a diagnostic index based on liver fat content to differentiate these stages. A total of 149 participants were enrolled from the Nutrition Health Atlas Project in 2019 (Stage 1, n = 92) and 2022 (Stage 2, n = 57). Serum levels of amino acids, free fatty acids (FFAs) and other organic acids were quantified using liquid or gas chromatography-mass spectrometry.

The associations between evening eating and quality of energy and macronutrients and obesity: the National Health and Nutrition Examination Survey (NHANES), 2003-2016.

Background: This study aimed to investigate the associations between evening eating and quality of energy and macronutrients and obesity among U.S. adults.

Specific macronutrient clusters associated with lower mortality risk: Evidence from NHANES 1999-2018.

Introduction: Accumulating evidence suggest that imbalanced macronutrient composition would increase the risk of chronic diseases. However, previous studies that predominantly focused on individual macronutrients often failed to thoroughly elucidate this complex association.

Objectives: This study aimed to comprehensively analyze the relationship between macronutrient clusters and all-cause mortality.

Impact of maternal and offspring smoking and breastfeeding on oesophageal cancer in adult offspring.

Numerous risk factors for oesophageal cancer are linked to lifestyle habits, but the role of early-life factors in its incidence and mortality is unclear. Using UK Biobank data, we explore the association among breastfeeding, maternal smoking, smoking in offspring, and oesophageal cancer risk in adult offspring via multivariable Cox regression. Here, we show that being breastfed, compared with not being breastfed, is associated with a lower risk of oesophageal cancer incidence (HR: 0.

Activity determination of Lu using TDCR-Čerenkov method.

The accuracy of measuring the activity of Lu is crucial for calibrating the instruments employed in clinical applications. To support the measurements of Lu solution, the existing TDCR-Čerenkov method has been extended for this nuclide. The contribution of β and γ transitions from Lu was taken into account in the extended method.

Global, regional and national burden of osteoarthritis in 1990-2021: a systematic analysis of the global burden of disease study 2021.

Objectives: To describe the prevalence and incidence of osteoarthritis as well as years lived with disability (YLDs) due to osteoarthritis in 204 countries and territories from 1990 to 2021 by age, sex and socio-demographic index (SDI, a composite of socio-demographic factors).

Methods: Data were acquired from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 (GBD 2021). The burden of osteoarthritis was estimated for 204 countries and territories from 1990 to 2021by incidence, prevalence and YLDs.

The association of 24-hour behavior rhythms with stroke among American adults with prediabetes/diabetes: evidence from NHANES 2011-2014.

Background: Emerging evidence suggests that circadian rhythms play a role in the regulation of cardiovascular diseases (CVDs). We aim to examine the relationship between the 24-hour behavior rhythms (activity-rest and feeding-fasting rhythms) and stroke.

Methods: The study included 3201 adult participants with prediabetes/diabetes from the National Health and Nutrition Examination Survey (NHANES) 2011-2014.

Long-term exposure to third-hand smoke could accelerate biological aging via mitochondrial dysfunction: Evidence from population and animal studies.

The relationship between third-hand smoke (THS) exposure and lifespan remains inadequately explored. Our study sought to clarify the effects of THS on aging and lifespan. In this pursuit, our cross-sectional analysis assessed hematological aging markers in 986 non-smokers and examined lifespan alterations using a Drosophila model.

[Trends in energy intake and percentage energy from macronutrients among Chinese adults in 1997-2011].

Objective: To describe the level and trend of energy consumption and percentage energy from macronutrients of three meals in Chinese adults from 1997 to 2011.

Methods: The China Health and Nutrition Survey database(1997-2011) was used to analyze the trends of energy consumption of three meals and percentage energy from macronutrients of adult men and women aged 18-80 years. The dietary survey was conducted using the 3-day 24-hour dietary review survey method, and the energy consumption of three meals was calculated through self-reported.

Trends and Disparities in Diet Quality and Nutrient Intake among US Adults by Bodyweight Status.

The prevalence of obesity has been increasing in the US. Among the multifactorial contributors to obesity, dietary factors stand out as primary drivers. Using data from NHANES, we investigated the trends and disparities in diet quality and nutrient intake among US adults with different bodyweight statuses.

Breastfeeding may reduce the effects of maternal smoking on lung cancer mortality in adult offspring: a prospective cohort study.

Background: Although previous research has indicated a correlation between smoking and the mortality rate in patients with lung cancer, the impact of early life factors on this relationship remains unclear and requires further investigation. This study aimed to investigate the hypothesis that breastfeeding reduces the risk of lung cancer-related death.

Methods: The authors conducted a prospective cohort study involving 501 859 participants recruited from the United Kingdom Biobank to explore the potential association between breastfeeding and the risk of lung cancer mortality using a Cox proportional hazards model.

Association between temperatures and type 2 diabetes: A prospective study in UK Biobank.

Objective: This study aims to prospectively examine the association between temperatures and the occurrence of type 2 diabetes (T2D).

Methods: We used the CPH models to analyze 103,215 non-diabetic participants in the UK Biobank cohort who answered questions about workplace temperature, to evaluate the survival relationship, and the interaction effects of working environmental temperature and T2D-related genetic risk scores (GRS) on the occurrence of T2D. The occurrence of T2D was assessed by hospital inpatient records.

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p.

Background: Cellular communication among different types of vascular cells is indispensable for maintaining vascular homeostasis and preventing atherosclerosis. However, the biological mechanism involved in cellular communication among these cells and whether this biological mechanism can be used to treat atherosclerosis remain unknown. We hypothesized that endothelial autophagy mediates the cellular communication in vascular tissue through exosome-mediated delivery of atherosclerosis-related genes.

Temporal relationships between blood glucose, lipids and BMI, and their impacts on atherosclerosis: a prospective cohort study.

Objectives: This study aimed to explore the temporal relationship between blood glucose, lipids and body mass index (BMI), and their impacts on atherosclerosis (AS).

Design: A prospective cohort study was designed.

Setting And Participants: A total of 2659 subjects from Harbin Cohort Study on Diet, Nutrition and Chronic Non-communicable Diseases, and aged from 20 to 74 years were included.