Publications by authors named "Binbin Ren"

Pyroptosis is an inflammatory form of cell death involving caspase-1 or caspase-4/5/11, initiated by inflammasomes or cytoplasmic endotoxins as part of the immune defense. It is specifically characterized by Gasdermin-mediated pore formation leading to cell lysis, pyroptosis also entails the release of pro-inflammatory cytokines. As a natural mechanism of the immune system, it activates in response to harmful stimuli to eliminate threats and facilitate tissue repair.

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Currently, there are no commercial serologic marker or differentiation of infected and vaccinated animal (DIVA) vaccines for the eradication of porcine reproductive and respiratory syndrome virus (PRRSV) infection from pig farms. In a previous study, a nanobody-based competitive ELISA (cELISA) was specifically developed to detect anti-genotype 2 PRRSV (PRRSV-2) antibodies. On the basis of the epitope recognized by the nanobody and the prevalence of PRRSV-2 infection in China, a DIVA vaccine candidate strain was designed and evaluated in the present study.

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Article Synopsis
  • - The study aimed to investigate how electroacupuncture (EA) affects the HIF/VEGF/Notch signaling pathways in rats with cerebral ischemia, focusing on its potential role in enhancing cerebral microangiogenesis and improving brain function.
  • - It included 100 male SD rats, with 15 in a sham group and the remaining 85 subjected to a cerebral ischemia model; various therapies, including EA and specific inhibitors, were administered to study their effects on neurological deficits and brain tissue characteristics.
  • - Results showed significant differences in neurological scores, cerebral infarct volume, microvascular density, and the expression of key proteins related to the signaling pathways in rats treated with EA compared to controls, highlighting the beneficial effects of EA
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Objectives: To evaluate the efficacy and safety of acupuncture combined with five-element music (FEM) as an therapeutic strategy for the physical and mental state of Post-stroke depression patients.

Design And Setting: Multicenter, randomized clinical trial conducted at 3 hospitals in China and enrolling 237 patients with PSD between June 2019 and April 2021. Participants mild/moderate PSD (17-item GRID Hamilton Depression Scale (HAMD) score 7-24) were randomly assigned (1:1) to acupuncture combined with FEM (AFEM) group or cognitive behavioral therapy (CBT) group.

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Objectives: To investigate the neuroprotective effect of electroacupuncture (EA) at "Quchi"(LI11) and "Zusanli"(ST36) in the rats with cerebral ischemia reperfusion injury and its influence on programmed necrosis of cerebral cortical neurons.

Methods: Sixty male SD rats were randomly divided into sham-operation group, model group, EA group and inhibitor group, with 15 rats in each group. Left middle cerebral artery occlusion model was established using the modified thread embolism method.

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Autoimmune hepatitis (AIH) is a chronic liver inflammatory disease with various immune system manifestations, showing a global trend of increased prevalence. AIH is diagnosed through histological abnormalities, clinical manifestations, and biochemical indicators. The biochemical markers involve interfacial hepatitis, transaminase abnormalities, positive autoantibodies, etc.

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Objective: To observe the effect of electroacupuncture (EA) of Governor Vessel (GV) on the expressions of glutamate decarboxylase 67 (GAD67) and γ-aminobutyric acid transaminase (GABA-T) in the cerebral cortex of rats with post-stroke limb spasticity, so as to explore its mechanism underlying improvement of limb spasticity.

Methods: Twenty four male SD rats were randomly and equally divided into control, sham operation, model, and EA groups. The cerebral ischemia model was established by occlusion of the middle cerebral artery (MCAO).

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Background And Purpose: To investigate the image quality and accurate bone mineral density (BMD) on quantitative CT (QCT) for osteoporosis screening by deep-learning image reconstruction (DLIR) based on a multi-phantom and patient study.

Materials And Methods: High-contrast spatial resolution, low-contrast detectability, modulation function test (MTF), noise power spectrum (NPS), and image noise were evaluated for physical image quality on Caphan 500 phantom. Three calcium hydroxyapatite (HA) inserts were used for accurate BMD measurement on European Spine Phantom (ESP).

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Background: Acupuncture is one of the most popular complementary and alternative treatments for knee osteoarthritis (KOA). There are many methods of acupuncture in the treatment of KOA, and the effects are different. According to our clinical observations and researches, it is found that manual acupuncture (MA), electro-acupuncture (EA), and warm acupuncture (WA) are used more frequently in the treatment of KOA, and the curative effects are satisfactory.

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In recent years, the medical field had significantly progressed to a greater extent which was evidenced with increased life expectancy and decreased mortality rate. Due to the growth of medical field, numerous communicable diseases are prevented and eradicated, whereas the non-communicable disease incidence has been increased globally. One such non-communicable disease which threatens the global population is stroke.

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Caowu, the main root of the plant, is widely used in China. Aconitine is the main toxic component of , which can cause a variety of malignant arrhythmias and lead to death. Four patients who developed malignant arrhythmia after drinking medicinal wine containing Caowu were reported in this study.

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Rational application of organic fertilizers is an effective approach to improve soil fertility, crop yield, and zero growth of chemical fertilizer in agricultural production. The rice variety 'Shennong9816' was planted in Shenyang, Liaoning Province, under seven different treatments: zero nitrogen fertilizer (CK), low nitrogen, 150 kg·hm(LN), medium nitrogen, 240 kg·hm (MN), high nitrogen, 330 kg·hm(HN), medium nitrogen with replacement of chemical N by 10% organic manure (OMN), medium nitrogen with replacement of chemical N by 20% organic manure (OMN), and medium nitrogen with replacement of chemical N by 30% organic manure (OMN). The effects of different treatments on photosynthetic rate, nitrogen absorption, nitrogen use efficiency, and yield were examined and the optimal fertilization scheme was determined.

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Background And Objectives: The timing of invasive mechanical ventilation (IMV) is controversial in COVID-19 patients with acute respiratory hypoxemia. The study aimed to develop a novel predictor called cumulative oxygen deficit (COD) for the risk stratification.

Methods: The study was conducted in four designated hospitals for treating COVID-19 patients in Jingmen, Wuhan, from January to March 2020.

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Clarifying changes in gastrointestinal tissue compressed by surgical stapler is a crucial prerequisite for stapler design optimization. For this study, a stapler was modified, and multifrequency bioimpedance of a porcine small intestine tissue compressed by the stapler was measured. The Cole model was fitted to the bioimpedance, and changes in tissue were analyzed using model parameters: G , extracellular fluid conductance; ΔG, intracellular fluid conductance; C , equivalent capacitance of cell membrane.

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Ensemble empirical mode decomposition(EEMD)is an effective method for non-stationary signal analysis,such as electrocardiogram(ECG)signals.However,the precision and correctness of EEMD are affected by the two parameters,ratio of the added noise and ensemble number.The values of two parameters are set relying on experience and lacking of adaptability for uncertain signals.

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A photo-medical capsule that emits blue light for Helicobacter pylori treatment was described in this paper. The system consists of modules for pH sensing and measuring, light-emitting diode driver circuit, radio communication and microcontroller, and power management. The system can differentiate locations by monitoring the pH values of the gastrointestinal tract, and turn on and off the blue light according to the preset range of pH values.

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In order to evaluate the impact of artificial reef on the communities of macrobenthos, from 2009 to 2012, samples were collected in four seasons at the artificial reef area and the control area in Jincheng area of Laizhou Bay from 9 cruises. A total of 35 macrobenthos species (4 phyla, 30 families) were recorded in the two areas, with 30 species in the artificial reef area, and 27 species in the control area. Results suggested that the two macrobenthos communities with different species composition could be discriminated.

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Our previous studies demonstrated that chloroplastic CO concentration (Cc) is not sufficient under high-nitrogen (N) supply in rice plants. In this research, we studied how aquaporins- (AQPs) mediated Cc under different N-supply levels. A hydroponic experiment was conducted in a greenhouse with three different N levels (low N, 0.

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Objective: To explore different regulatory effects of electroacupuncture (EA) at the same acupoint on the heart and the stomach.

Methods: Eighty male SD rats were randomly divided into eight groups equally, i.e.

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Gastric dysmotility is one of the major pathophysiological factors in functional gastrointestinal disorders. Acupuncture, as one of the alternative approaches, is efficacious in the treatment of gastrointestinal motility disorders; however, the mechanism underlying its action is unclear. In the present study, we used both capsazepine, a TRPV1 antagonist, and TRPV1 knockout mice.

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Background: Stroke presents as a transient or chronic brain dysfunction and is associated with high morbidity and high mortality. The doctors and scientists would like to argue how to enhance the validity of the rehabilitation treatment and how to further improve the level of treatment on stroke.

Objective: The aim of this study was to quantitatively analyze the current worldwide progress in research on stroke rehabilitation treatment based on Web of Science database and ClinicalTrial.

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