Using robotic single-port vNOTES for gynaecological oncology: omentectomy in a patient with an ovarian granulosa cell tumor-a case study.

Background: Robotic single-port transvaginal natural orifice transluminal endoscopic surgery (RSP-vNOTES) is an emerging minimally invasive approach that combines the advantages of robotic surgery with scarless transvaginal access. Its application in gynecologic oncology remains limited, particularly for omentectomy during ovarian cancer staging.

Methods: We present the case of a 45-year-old woman with an ovarian granulosa cell tumor (GCT) who underwent supplemental staging surgery following unilateral oophorectomy.

Repeat stereotactic radiosurgery for treatment of brain metastases locally recurrent following initial radiosurgery.

Purpose: We report outcomes of repeat stereotactic radiosurgery (rSRS) to sites of tumor progression following initial SRS. Additionally, we sought to determine if, at the time of recurrence following initial SRS, surgical resection of the tumor followed by SRS (surgery + rSRS) provided benefit compared to rSRS alone.

Methods: We retrospectively reviewed patients treated with rSRS for local recurrence after initial SRS.

Robotic upper urinary tract reconstruction for ureteral stricture: a single-center series.

The surgical approach of ureteral stricture has changed dramatically over the past 15 years with the rise of robotic upper urinary tract reconstruction. This study aimed to evaluate the outcomes of all robotic ureteral reconstructions performed at a single academic center for ureteral stricture and to assess the predictive factors of stricture recurrence. The charts of all patients who underwent robot-assisted ureteral reconstruction between 2013 and 2024 at a single academic center were retrospectively reviewed.

Redefining robotic surgical education: teleproctoring feasibility and trainee perception.

Teleproctoring offers a remote alternative to traditional surgical mentoring, addressing logistical barriers in robotic surgery education. We conducted a prospective trial to assess the feasibility and trainee perception of teleproctoring using the Proximie platform. Eighteen surgeons with limited robotic experience performed a standardized enterotomy closure on synthetic bowel models using the da Vinci Si system, while receiving real-time remote guidance from an expert located 2570 km away.

Roman Catholic Religious Affiliation and Reactions to the Initial Stage of the COVID-19 Pandemic in Poland.

The present study examined responses to COVID-19 at the beginning of the pandemic, April 2020, among a representative sample of 880 Poles. Participants described their religious beliefs, their emotional reactions to the pandemic, the changes they had made in their behavior since the onset of the pandemic, and their political orientation (left-right). Roman Catholics felt more threatened by the pandemic than non-believers, and Catholics reacted more strongly to the pandemic than non-believers in terms of feeling scared, paralyzed by fear, panicked, fearful, sad, woebegone, and lost, whereas there were no such differences on other emotional reactions.

Plasma transfusion practice: A five-year audit of plasma transfusion at 23 hospitals.

Background: There is limited high-quality evidence to guide plasma transfusion, and plasma transfusion practices remain variable.

Study Design And Methods: This is a retrospective cohort study that included adult medical and intensive care unit (ICU) inpatients (age ≥ 18 years) admitted to 23 hospitals in Canada between January 1, 2017, and December 31, 2022, when both whole blood derived (~290 mL) and apheresis plasma (~250 mL) were available for transfusion. Nine additional hospital sites with missing plasma data or coagulation testing were excluded.

Delivering opioid use disorder treatment among American Indian and Alaska Native adults during the COVID-19 pandemic and beyond: Facilitators and barriers to care.

Background: American Indian and Alaska Native (AI/AN) communities experienced a disproportionate increase in opioid-related fatal and non-fatal poisonings during the COVID-19 pandemic. Access to treatment, such as medications for opioid use disorder (MOUD), became even more critical, although research among this population is limited. We completed qualitative interviews with substance use disorder (SUD) treatment providers (i.

Artificial Intelligence Automation of Echocardiographic Measurements.

Background: Accurate measurement of echocardiographic parameters is crucial for the diagnosis of cardiovascular disease and tracking of change over time; however, manual assessment requires time-consuming effort and can be imprecise. Artificial intelligence has the potential to reduce clinician burden by automating the time-intensive task of comprehensive measurement of echocardiographic parameters.

Objectives: The purpose of this study was to develop and validate open-sourced deep learning semantic segmentation models for the automated measurement of 18 anatomic and Doppler measurements in echocardiography.

Attribute preferences associated with gonadotropin-releasing hormone agonists/antagonists among women with endometriosis in the United States.

Background: Endometriosis symptoms have multifaceted manifestations, and there are few approved nonsurgical treatment options. Gonadotropin-releasing hormone (GnRH) agonists/antagonists for endometriosis vary on efficacy, safety profile, and out-of-pocket (OOP) cost, among other features.

Objectives: This study quantified the importance that women with endometriosis in the United States (US) placed on pain and non-pain features that differ among these medications.

Evaluation of Kindergarten Through Grade 12 All-Cause Absenteeism Data as an Indicator and Predictor of Respiratory Disease, 2018-2022.

Objectives: Increases in absenteeism among schoolchildren may precede increases in incidence of community-level respiratory diseases. This study assessed the correlations and predictive values between all-cause absenteeism among kindergarten through grade 12 students and community-level increases in influenza and COVID-19.

Methods: We used absenteeism data from 4 school districts (1 each in Arizona, California, Nevada, and Wisconsin) between fall 2018 (starting approximately late August) and spring 2022 (typically ending in May) to calculate correlations between school absenteeism and community-level cases of influenza, percentage of influenza-like illness, and COVID-19.

Implementation of Mobile Medical Units for Veterans Experiencing Homelessness: A Mixed-Methods Study.

Objectives: Mobile medical units (MMUs) provide health care services in the community to reach populations with geographic, financial, and other barriers to care. The US Department of Veterans Affairs (VA) Homeless Patient Aligned Care Team (HPACT) program deployed MMUs to 25 sites in fiscal year 2024 to increase access for veterans experiencing homelessness. We examined early implementation of MMUs in HPACT sites by describing implementation and operational issues, services provided, and characteristics of veterans who used MMUs.

The Experiences of Patients With Rare Diseases in Pennsylvania: A Community-Based Study.

Objective: Rare diseases collectively affect approximately 30 million people in the United States. Despite advances in genomic medicine, early diagnosis is challenging because of limited awareness of, accessibility to, and disparities in health care resources. We assessed the real-world experiences of patients with rare diseases in Pennsylvania and evaluated the effect of delayed diagnosis on psychosocial and financial burdens.

Wastewater Monitoring: Improving Public Awareness and Understanding in the United States, May 2024.

Objectives: Although wastewater monitoring for virus detection has increased in communities worldwide, public awareness, understanding, questions, and concerns about wastewater monitoring are largely unknown. We assessed awareness, knowledge, and support for wastewater monitoring for detection of viruses and bacteria among US residents and elicited questions and concerns from residents about its use.

Methods: We conducted a survey among a racially and ethnically diverse sample of residents in Colorado, Maryland, Missouri, Nebraska, and Texas to assess awareness, knowledge, and support of wastewater monitoring.

Advances, challenges, and future directions in trauma-related Findable, Accessible, Interoperable, Reusable (FAIR) data efforts.

Findable, Accessible, Interoperable, and Reusable (FAIR) data advances are becoming more common and more important across research fields given the large amount of research data in need of synthesis and application. Many novel methods improve the efficiency and accuracy of data reuse, combination, and synthesis, which is necessary given that there are over 500 published randomized controlled trials of posttraumatic stress disorder treatments in adults; however, these methods are still relatively new to the field of traumatic stress research. We provide a brief overview of relevant FAIR data efforts from other fields and within trauma health care and research; share examples of trauma-related FAIR data efforts to demonstrate recent advances and challenges; and suggest potential next steps to continue making trauma data more FAIR.

Does Weightbearing Affect Radiographic or Clinical Outcomes in Distal Radius Fractures Treated With Dorsal Bridge Plate Fixation?

Background: Dorsal wrist spanning plate (DWSP) fixation in distal radius fractures (DRFs) has been proposed to allow earlier mobilization in polytraumatized patients by enabling early weightbearing (WB) through the injured wrist. The purpose of this study is to compare radiographic and clinical outcomes in patients who bore weight through the injured wrist within the early postoperative period with patients who did not bear weight.

Methods: Patients who underwent DWSP fixation at a single institution were retrospectively identified.

Evaluating the Educational Quality and Accuracy of Carpal Tunnel-and Cubital Tunnel-Related Videos on TikTok.

Background: The increased utilization of social media platforms, including TikTok, has revolutionized the way that medical information is disseminated and consumed globally. Despite the benefits of rapidly accessible health information, the unregulated nature of TikTok raises significant concerns for the validity and reliability of medical advice. The purpose of this study is to evaluate the educational quality and accuracy of information presented on TikTok relating to carpal tunnel syndrome (CTS) and cubital tunnel syndrome (CubTS), 2 common upper extremity conditions.

Evaluating the Feasibility and Acceptability of a Mobile Mental Health Intervention for Adolescent Depression and Anxiety.

The adolescent mental health crisis is compounded by a shortage of mental health services, which mobile health apps may alleviate. We assessed the feasibility and acceptability of the Wysa app (a commercially available app containing cognitive behavioral therapy-based digital modules and an artificial intelligence-based conversational agent) among 13- to 18-year-old adolescents recruited from a primary care clinic in New York City and online from March to June 2022. We assessed adolescent engagement in the Wysa app over a 3-week period.

Relationship Between Household Social Risk and Symptoms of Depression and Anxiety in Adolescents: A Retrospective Cohort Study.

Research suggests that household social risks are associated with worse mental health in adolescents, but prior studies have been limited. We evaluated the association between social risks and symptoms of depression and anxiety in adolescents 1 year later by conducting a retrospective cohort study at an integrated health system with 45 practices. Adolescents were screened for depression using the Patient Health Questionnaire-2 (PHQ-2) and anxiety using the Generalized Anxiety Disorder-2 (GAD-2).

Qualitative Evaluation of HealthySteps Implementation in Urban Pediatric Primary Care Clinics.

HealthySteps is an evidence-based, prevention program for families of children ages 0 to 3 integrated into pediatric primary care. Our objective was to synthesize feedback on local implementation of an enhanced HealthySteps+ program from various stakeholder viewpoints to improve implementation. Qualitative data were gathered from HealthySteps+ team members (n = 14), current clinic staff (n = 15), and a focus group of parents serving on the program's advisory committee (n = 7).

Exploring Early Perceptions and Experiences of ChatGPT in Pediatric Critical Care: A Qualitative Study Among Health Care Professionals.

To optimize the deployment of Generative Artificial Intelligence in health care, it's essential for health care professionals (HCPs) to understand these technologies' capabilities and constraints. This study explores HCPs' initial impressions and experiences using ChatGPT, a Generative Pre-trained Transformer, in Pediatric Critical Care Units (PICUs). By conducting focus groups with a diverse set of HCPs, we aimed to assess their awareness, utilization, perceived benefits, and concerns about incorporating ChatGPT into their PICUs.

Atomic-Scale Mechanistic Insights into the Ring-Opening Polymerization of Elemental Sulfur.

A detailed understanding of the composition and polymerization mechanism of elemental sulfur remains a decades long unresolved question for modern chemistry. However, the dynamic nature of molten sulfur significantly complicates its accurate characterization. To overcome this challenge, we performed the first comprehensive molecular dynamics (MD) simulations using a ReaxFF reactive force field specifically parameterized to capture the complex ring-opening polymerization dynamics of elemental sulfur.