A Microfluidic Chip-Based Integrated Device Combining Aerosol Sampling and LAMP-CRISPR Detection for Airborne Virus Surveillance.

Detecting airborne viruses using an integrated aerosol sampling detection device is of great significance in epidemic prevention and control. Most of the applicable aerosol samplers have a flow rate of less than 1000 L/min, which is insufficient for application in large public spaces. Recent research, on the other hand, has revealed the advantages of microfluidic chip-based LAMP-CRISPR in airborne virus detection; however, this promising detection method has yet to be integrated with an aerosol sampler.

Low-Level Environmental Metals Exposures, Biomarkers of Myocardial Injury and Hemodynamic Stress, and Mortality Risk.

Background: The exact pathophysiologic mechanism of environmental toxic metals (particularly lead and cadmium)-associated cardiovascular events remains poorly understood.

Objectives: The authors assessed the impacts of lead and cadmium on myocardial injury and stress and further explored their roles in the risks of all-cause and cardiovascular mortality.

Methods: We included participants with studied measurements from the National Health and Nutrition Examination Survey between 1999 and 2004, followed up to 2019.

Combined Toxicity of Heavy Metal Cadmium and Insecticide Chlorpyrifos to Drosophila S2 Cells.

Cadmium (Cd) is a heavy metal, and chlorpyrifos (CPF) is a widely used organophosphorus insecticide, which are widespread environmental pollutants. These two chemicals can induce the production of reactive oxygen species (ROS) in mammals and cause oxidative damage. However, the mechanism of their combined toxicity in invertebrates and especially insects has not been well documented.

Oral exposure to LaNiO regulates the immune system, modulates gut flora, and induces intestinal autophagy in mice.

LaNiO exhibits outstanding physical and chemical properties, demonstrating promising potential for regulating immune responses in disease contexts. We discovered that LaNiO promotes autophagy and immune suppression. After oral administration of LaNiO in mice (7 days post single exposure at a dose of 10 mg kg), techniques from metallomics, microbiology, metabolomics, and molecular biology are used to evaluate toxicity, elemental distribution, intestinal autophagy, immune suppression, and effects on intestinal microbiota and metabolites.

[Investigation and analysis of occupational disease risk assessment index system in the automotive repair industry].

To construct a risk assessment index system for occupational disease hazards in the automotive repair industry using the Delphi method, providing a scientific basis and systematic evaluation framework for occupational hazard management in this sector. In January 2024, an expert survey method was employed to identify occupational hazard risk indicators through in-depth expert discussions. A multidimensional and hierarchical assessment system was designed based on the two core elements of "comprehensive prevention-on-site hazards.

Rapid Detection of Illicit Drugs: An Analysis of Research Progress and Prospects.

Rapid detection of illicit drugs has garnered significant attention for its role in preventing and controlling drug abuse, supporting treatment management in healthcare systems, and environmental monitoring. Although various reviews have explored specific methods, samples, or analytes in rapid illicit drug detection, a comprehensive analysis summarizing overall trends in this field remains absent. To support the development and broader application of rapid drug detection technologies, a bibliometric analysis of relevant literature from 2001 to 2023 is conducted, presenting a general bibliometric distribution of studies by year, country, institution, author, journal, and research focus.

Life-long impacts of nanoplastics to rice plant (Oryza sativa L.): Decreased grain yield with perturbed metallome and soil microbiome.

Approximately 367 million metric tons of plastic were produced globally in 2020, and it is projected that the global plastic waste will reach around 12,000 metric tons by 2050. Plastic waste can be fragmented into nanoplastics (NPs). Despite their widespread presence in the environment and even within the human body, the long-term risks of NPs to plants, animals, and humans remain poorly understood.

Surveillance of noise exposure levels in workplaces in Beijing.

Occupational noise-induced deafness is the second most prevalent occupational disease in China after pneumoconiosis. This study aims to estimate overall noise exposure levels and trends in industrial enterprises in Beijing. A total of 286 enterprises were monitored, and the median and interquartile range (IQR) of noise exposure levels were calculated.

Maternal benzo[a]pyrene exposure during critical gestational periods impairs offspring neurological development in rats: a mechanistic study of the Wnt/β-catenin signaling pathway.

Introduction: Mid-gestation is a critical period for the development of the nervous system. Exposure to exogenous harmful chemicals during this period may lead to longterm neurological developmental abnormalities in offspring. Benzo[a]pyrene (B[a]P) is a commonly occurring neurotoxic environmental pollutant that can pass through the placental barrier and blood-brain barrier (BBB), thereby affecting placental nerve development.

Study on the in-situ modified support method of roadway surrounding rock under vertical impact load.

With the deepening of coal mining, the frequency and intensity of rock burst accidents are increasing. According to incomplete statistics, there have been over 200 rock burst accidents in tunnels in China alone from 2005 to 2024, resulting in more than 500 deaths and causing extensive damage to tunnel equipment. Therefore, research on tunnel surrounding rock support methods is urgently needed.

Ultrasensitive detection of methamphetamine in environmental water bodies by an Au@carbon dots/chitosan nanocomposite modified electrochemical aptasensor.

Background: The robust analytical methods for methamphetamine (METH), the second most widely used illicit drug globally, in aqueous environments are essential for on-site detection of regional drug abuse and pollution, and then timely control its threat to ecological environment and public health.

Results: A simple and label-free electrochemical aptasensor based on aptamer/Au@carbon dots/chitosan nanocomposite modified gold electrode (Apt/Au@CDs/CS/AuE) was firstly developed for measuring trace METH in environmental water bodies. The aptamer was immobilized on Au nanoparticles through Au-N bond, where carbon dots provided large surface area for good dispersion of nanomaterials.

Study on Acoustic Properties of Helmholtz-Type Honeycomb Sandwich Acoustic Metamaterials.

In order to improve the acoustic performance of honeycomb sandwich structures, a Helmholtz-type honeycomb sandwich acoustic metamaterial (HHSAM) was proposed. The theoretical and finite element models were established by calculating the acoustic impedance of multiple parallel Helmholtz resonators (HR). By comparing the sound absorption of the single and multiple HR, it was found that the simulation results were basically consistent with the theoretical calculations.

The impact of school heavy metal exposure on children's gut microbiota: The mediating role of environmental microorganisms.

Heavy metals are toxic and harmful pollutants that can affect the school environment and the exposed children's health. This study collected dust samples and children's fecal specimens, and performed gene sequencing. We used eXtreme Gradient Boosting to determine the impact of heavy metals on environmental microorganisms and gut microbiota, while using the relative length of the quadrant and Fourth-corner analysis to explore the relationship among the three components.

Numerical Simulation Study on Methane Diffusion Distribution Laws in Confined Spaces of Municipal Heating Underground Pipe Trenches.

In order to study the diffusion distribution laws of harmful gases in municipal heating underground pipe trenches under various influencing factors, a 1:1 scale model of the municipal heating underground pipe trench was established by using CFD simulation software. This study examined the impact of closed pipe trench conditions, natural ventilation, mechanical ventilation, and gas dispersing rates on the distribution of methane diffusion in the heating underground pipe trench and was verified through on-site experiments. The findings are as follows: (1) the gas in the heating pipe trench flows violently at the bottom of the pipe trench and the examination room and the top air flow rate is small, resulting in higher top temperature and lower bottom temperature; (2) under closed trench conditions, methane gas exhibits a vertical layered distribution near the release source, with higher concentrations in the upper part compared to the lower part.

Challenges of aligning district heating structures with climate goals across China's provinces.

Cost-effective decarbonization and clean heating, the major end-use of energy in China, is an urgent scientific challenge. This study proposed a generalizable framework to quantify facility-level cost-effectiveness to assess the application scope and emission reduction potential of various strategies, while evaluating their provincial compatibility with carbon neutrality goals. Our findings indicate that China's district heating system emitted 7.

Multi-scenario adaptive electronic nose for the detection of environmental odor pollutants.

With the rapid development of sensing technologies, electronic noses have become an important tool for real-time environmental monitoring, but ensuring their applicability and accuracy across various scenarios remains a key challenge. In this study, an electronic nose system with multi-scenario applicability and enhanced accuracy was developed to measure four common key pollutant concentrations in three typical pollution scenarios: landfills, wastewater treatment plants and livestock farms. A scenario-adaptive strategy was proposed to minimize the impact of interferences on the measurement accuracy by constructing a hierarchically structured qualitative-scenario-specific qualitative sub-network to process the sensor response data.

Analysis of typical unsafe behaviors and common characteristics in accidents: a case study of accidents occurring over the past 3 years in China.

The direct cause of safety accidents is the unsafe behavior of production personnel. The fundamental approach to reducing all types of accidents is to prevent and control the occurrence of unsafe behavior among production personnel. This article identifies the cases of safety accidents in the past 3 years, analyzes the typical unsafe behaviors in the accidents, constructs the correlation network of unsafe behaviors and their characteristics, conducts the correlation analysis of unsafe behaviors and characteristic elements based on the correlation rules, determines the common characteristics of unsafe behaviors and puts forward the targeted measures.

Review of pretreatment and analytical methods for environmental endocrine disruptors: phthalates.

Phthalates, known as phthalate esters (PAEs), are among the most ubiquitous pervasive environmental endocrine disruptors, extensively utilized globally in various facets of modern life due to their irreplaceable role as plasticizers. The exponential production and utilization of plastic goods have substantially escalated plastic waste accumulation. Consequently, PAEs have infiltrated the environment, contaminating food and drinking water reservoirs, posing notable threats to human health.

A platform noise dataset of various types of subway stations during all operating hours.

The subjective perceptions of passengers are intricately linked to the noise levels in subway stations of urban rail transit systems. In this study, comprehensive measurement was conducted on the noise environment on the platforms during operational hours at four distinct types of subway stations within an urban metro network. To ensure precise data collection, four different noise and sound pressure measurement points were strategically positioned in the middle and at both ends of each station platform.

Dynamic Methane Emissions from China's Fossil-Fuel and Food Systems: Socioeconomic Drivers and Policy Optimization Strategies.

In response to the 2023 "Action Plan for Methane Emission Control" in China, which mandates precise methane (CH) emission accounting, we developed a dynamic model to estimate CH emissions from fossil-fuel and food systems in China for the period 1990-2020. We also analyzed their socioeconomic drivers through the Logarithmic Mean Divisia Index (LMDI) model. Our analysis revealed an accelerated emission increase (850.

Cytotoxicity and Antimicrobial Efficacy of Fe-, Co-, and Mn-Doped ZnO Nanoparticles.

Zinc oxide nanoparticles (ZnO NPs) are one of the most widely used nanoparticulate materials due to their antimicrobial properties. However, the current use of ZnO NPs is hindered by their potential cytotoxicity concerns, which are likely attributed to the generation of reactive oxygen species (ROS) and the dissolution of particles to ionic zinc. To reduce the cytotoxicity of ZnO NPs, transitional metals are introduced into ZnO lattices to modulate the ROS production and NP dissolution.

Historical inventories and future scenarios of multiple hazardous air pollutants (HAPs) emissions from the iron and steel production industry in China.

Iron and steel production (ISP) is one of significant atmospheric pollution emission sources in China. With the implementation of ultra-low emission (ULE) standards, a detailed and new updated emission inventory is urgently needed for better understanding of the temporal trends and spatial variation of emission characteristics. In this study, a unit-based comprehensive emission inventory of multiple hazardous air pollutants (HAPs) for the Chinese ISP spanned from 2012 to 2021, including the conventional pollutants, 13 kinds of Trace elements as well as 2 unconventional but toxic pollutants (PCDD/Fs, F), was dedicatedly developed by integrating dynamic localized emission factors with unit-based information of both the detailed activity level and abatement technology application.

Effects of combined exposure to PM, O, and NO on health risks of different disease populations in the Beijing-Tianjin-Hebei region.

Air pollution adversely affects people's health. Under the current background of compound air pollution in China, the emission reduction potential of air pollution control has significantly decreased, and there are few studies on multi-pollutant emission reduction and synergistic effects. PM, O, and NO have caused the enormous disease burden and health risks.

Tracking Carbon and Ammonia Emission Flows of China's Nitrogen Fertilizer System: Implications for Domestic and International Trade.

China is the world's largest producer, consumer, and exporter of synthetic nitrogen (N) fertilizer. To assess the impact of domestic demand and international exports, we quantified the life-cycle COeq and ammonia (NH) emissions by tracking carbon (C) and nitrogen (N) flows from coal/gas mining through ammonia production to N fertilizer production, application, and export. In 2020, China's N fertilizer system emitted 496.

Polycyclic aromatic hydrocarbon and its adducts in peripheral blood: Gene and environment interaction among Chinese population.

Background: Benzo(a)pyrene (B[a]P) is the most widely concerned polycyclic aromatic hydrocarbons (PAHs), which metabolizes benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE) in vivo to produce carcinogenic effect on the body. Currently, there is limited research on the role of the variation of metabolic enzymes in this process.

Methods: We carried out a study including 752 participants, measured the concentrations of 16 kinds PAHs in both particle and gaseous phases, urinary PAHs metabolites, leukocyte BPDE-DNA adduct and serum BPDE- Albumin (BPDE-Alb) adduct, and calculated daily intake dose (DID) to assess the cumulative exposure of PAHs.