Patient-reported outcome tools of acupuncture clinical trials in mainland China: a cross-sectional study.

Background And Objective: Nowadays, the number of acupuncture clinical trials is dramatically increasing. In acupuncture clinical research, patient-reported outcome measurements are important evaluation tools, but there is a lack of systematic survey. This study aims to evaluate the characteristics and application of PRO measurements in acupuncture clinical trials in mainland China, further exploring and developing patient-reported outcomes (PROs) that are in line with the characteristics of acupuncture treatment.

Bio-Inspired Controllable Liquid Transfer: From Fundamentals in Micro-Patterning to Applications in Optoelectronics.

Solution-processed micro-patterning is a crucial process for making high-performance optoelectronic devices, since the carrier transfer behavior is closely related to the uniformity, orientation, and resolution of micro-patterns. Developing solution processes with good controllability has thus attracted increasing research interest in the last decade. Inspired by Chinese brushes, a fibrous-guided direct-writing strategy is recently developed that enables controllable liquid transfer for making micro-patterns, which is systematically reviewed from viewpoints of both the fundamentals in liquid manipulation and the applications in optoelectronics.

Super-resolution imaging informed scRNA sequencing analysis reveals the critical role of GDF15 in rejuvenating aged hematopoietic stem cells.

Although changes in mitochondrial morphology consistently associated with the aging of hematopoietic stem cells (HSCs), the specific molecular and cellular mechanisms involved are partially unclear. Live-cell super-resolution (SR) microscopy has been used to identify distinct HSC subsets that characterized by mitochondria unique morphologies and spatial distributions. The integration of SR microscopy with single-cell RNA sequencing enabled the classification of approximately 200 HSCs from young and aged mice into 5 discrete clusters.

Module architecture analysis and application of glycoside hydrolase family 148 thermostable β-1,3-1,4-glucanase.

β-1,3-1,4-Glucanases have attracted significant interest because of their potential applications in various food industries. Glycoside hydrolase (GH) family 148 β-1,3-1,4-glucanases exhibit excellent thermal stability and a unique catalytic mechanism, making them particularly promising for certain food processing applications. This study investigated the module architecture enzymatic properties, catalytic mechanisms, and potential applications of a multi-domain β-1,3-1,4-glucanase (EngU) from GH family 148.

Solution-Processed Quantum Dot Micropatterns: From Liquid Manipulation to High-Performance Quantum Dot Light-Emitting Diode Devices.

Micropatterning quantum dots (QDs) is a key process for making high-performance quantum dot light-emitting diodes (QLEDs), which have shown advantages in lighting and displays. So far, various solution processes have been developed for fabricating micropatterned QDs, where both uniform distribution and well-defined edges are desirable. Very recently, with the flourishing of near-eye displays, high-resolution QD micropatterns appear particularly attractive, which regretfully have progressed poorly due to the extremely complicated liquid dynamics at microscale.

Enhanced Reconfigurable Visual Cryptography Strategies Utilizing Optical Metasurfaces.

The secure storage and transmission of information are core measures that ensure data security. Within intricate information landscapes, reconfigurable encryption mechanisms serve as robust defenses against potential breaches of encrypted data. Here, we propose a reconfigurable visual secret sharing (VSS) encryption strategy that leverages the capabilities of optical metasurfaces and exhibits a dual-channel secondary encryption scheme.

3D printing of antimicrobial adsorbents using Mercapto-graphene oxide / chitosan / ε-Polylysine: Elucidating adsorption mechanisms and antimicrobial performance.

Cu in wastewater is hazardous to human health, and adsorption technology can effectively remove heavy metal ions. In this study, sulfhydryl graphene oxide/chitosan/ε-polylysine (SGCS-E) polymeric antimicrobial materials were prepared using 3D printing technology. These materials were characterized using scanning electron microscopy, Fourier transform infrared spectroscopy, and XPS.

A splice mutation in gene in the patient with recurrent epistaxis and nasal vascular malformation.

Platelet type bleeding disorder-18 (BDPLT18) caused by mutations of Ras guanyl releasing protein 2 () is a relatively rare, new autosomal recessive disorder. Here, we reported a splice mutation in gene in the patient with recurrent epistaxis and nasal vascular malformation. The patient, an 8-year-old girl, suffered from anemia due to frequently severe recurrent epistaxis, requiring regular blood transfusions every 2-3 months.

Continuous Homogeneous Thin Liquid Film on a Single Cross-Shaped Profiled Fiber with High Off-Circularity: Toward Quick-Drying Fabrics.

Quick-drying fabrics, renowned for their rapid sweat evaporation, have witnessed various applications in strenuous exercise. Profiled fiber textiles exhibit enhanced quick-drying performance, which is attributed to the excellent wicking effect within fibrous bundles, facilitating the rapid transport of sweat. However, the evaporation process is not solely influenced by macroscopic liquid transport but also by microscopic liquid spreading on the fibers where periodic liquid knots induced by spontaneous fluidic instability significantly reduce the evaporation area.

Biochemical properties and application of a multi-domain β-1,3-1,4-glucanase from Fibrobacter sp.

A novel glycoside hydrolase (GH) family 16 multi-domain β-1,3-1,4-glucanase (FsGlc16A) from Fibrobacter sp. UWP2 was identified, heterogeneously expressed, and its enzymatic properties, protein structure and application potential were characterized. Enzymological characterization showed that FsGlc16A performed the optimal catalytic activity at pH 4.

The Barriers to Insulin Therapy Initiation in Type 2 Diabetes Patients: A Study of General Practitioner Perceptions in Huinan Community in South Shanghai.

Background: Despite the demonstrated benefits of insulin therapy, many general practitioners (GPs) are hesitant to administer it due to challenges such as a lack of knowledge, time constraints, and patient reluctance. The barriers that prevent a GP from initiating insulin therapy may vary in comparison to those encountered by a diabetic patient; this aspect of clinical research in the South Shanghai metropolitan area has received limited attention so far.

Objective: This is a 6-months of interventional analytic cohort study.

High-absorption optical stack for aluminum kinetic inductance detectors.

We present a high-absorption optical stack design for aluminum (Al) kinetic inductance detectors (KIDs). Aluminum can be easily processed in micro-fabrication and is the most conventional superconducting material for KIDs. However, it is challenging to achieve high absorption in the Al absorber because of its high reflection at optical wavelengths.

Yiqi Jiedu decoction attenuates radiation injury of spermatogenic cells via suppressing IκBα/NF-κB pathway-induced excessive autophagy and apoptosis.

Ethnopharmacological Relevance: The prescription of Yiqi Jiedu decoction (YQJD) originated from the classic Chinese herbal prescriptions of Danggui Buxue Decoction and Wuzi Yanzong Pill. A previous study has shown that 4 Gy irradiation induced the apoptosis of spermatocytes and revealed autophagosomes in cells exposed to radiation. YQJD decoction has the effect of preventing radiation injury.

Direct air capture (DAC) and sequestration of CO: Dramatic effect of coordinated Cu(II) onto a chelating weak base ion exchanger.

Direct air capture (DAC) is important for achieving net-zero greenhouse gas emissions by 2050. However, the ultradilute atmospheric CO concentration (~400 parts per million) poses a formidable hurdle for high CO capture capacities using sorption-desorption processes. Here, we present a Lewis acid-base interaction-derived hybrid sorbent with polyamine-Cu(II) complex enabling over 5.

New developments during the COVID-19 pandemic: Drama therapy as an online psychological intervention tool.

The COVID-19 pandemic has caused many art therapists and psychotherapists to change their practice modes and workplace setup. As a creative arts therapy (CAT), drama therapy has also shifted to an online mode-a shift that has been highly consequential for practice. This reviews the existing practice of tele-CAT and tele-drama therapy, explores the advantages and disadvantages of online drama therapy as a psychological intervention tool, and puts forward some developmental suggestions for online drama therapy.

Significantly improved antifouling capability of silicone rubber surfaces by covalently bonded acrylated agarose towards biomedical applications.

Bacteria have the extraordinary ability to adhere to biomaterial surfaces and form multicellular structures known as biofilms, which have a detrimental impact on the performance of medical devices. Herein, an investigation highlighted the effective inhibition of bacteria adhesion and overgrowth on silicone rubber surface by grafting polysaccharide, agarose (AG), to construct hydrophilic and negatively charged surfaces. Because of the strong hydration capacity of agarose, the water contact angle of the modified silicone rubber surfaces was significantly reduced from 107.

Protective effects of Yiqi jiedu decoction on ionizing radiation-induced spermatogenic cell injury.

Ethnopharmacological Relevance: Ionizing radiation (IR) has found widespread application in modern medicine. As a result, radiotherapy inevitably causes spermatogenic cell injury. Many Chinese herbal prescriptions or natural extracts have the potential to protect against radiation injury.

The injuries of spleen and intestinal immune system induced by 2-Gy Co -ray whole-body irradiation.

Purpose: The aim of the present study was to investigate the injuries of spleen and intestinal immune system induced by 2 Gy Co γ ray in mice.

Materials And Methods: A total of 120 Balb/c mice were randomly divided into two groups: blank control (Ctrl) and model (IR). The IR mice were exposed to a single dose of total body irradiation (2 Gy, dose rate: 1 Gy/min) and sacrificed on 1st, 3rd, 7th, 14th and 21st day after irradiation.

Electrochemical On-Site Switching of the Directional Liquid Transport on a Conical Fiber.

Directional liquid transport (DLT), especially that proceeding on a conical fiber (DLT-CF), is an important mass-transfer process widely used both by natural organisms and in practical applications. However, on-site switching of the DLT-CF remains a challenge due to the nontunable driving force imparted by the structural gradient, which greatly limits its application. Here, unprecedently, a facile electrochemical strategy is developed for reaching the on-site switchable DLT-CF, featuring in situ control and fast response.

High-Sensitivity and Environmentally Friendly Humidity Sensors Deposited with Recyclable Green Microspheres for Wireless Monitoring.

The reliable, high-sensitive, wireless, and affordable requirements for humidity sensors are needed in high-precision measurement fields. Quartz crystal microbalance (QCM) based on the piezoelectric effect can accurately detect the mass changes at the nanogram level. However, water-capture materials deposited on the surface of QCM generally show disadvantages in either cost, sensitivity, or recyclability.

Multisensory integration attenuates visually induced oculomotor inhibition of return.

Inhibition of return (IOR) is a mechanism of the attention system involving bias toward novel stimuli and delayed generation of responses to targets at previously attended locations. According to the two-component theory, IOR consists of a perceptual component and an oculomotor component (oculomotor IOR [O-IOR]) depending on whether the eye movement system is activated. Previous studies have shown that multisensory integration weakens IOR when paying attention to both visual and auditory modalities.

Ferroptosis plays an important role in promoting ionizing radiation-induced intestinal injuries.

The intestinal tract is an essential component of the body's immune system, and is extremely sensitive to exposure of ionizing radiation. While ionizing radiation can effectively induce multiple forms of cell death, whether it can also promote ferroptosis in intestinal cells and the possible interrelationship between ferroptosis and intestinal immune function has not been reported so far. Here, we found that radiation-induced major ultrastructural changes in mitochondria of small intestinal epithelial cells and the changes induced in iron content and MDA levels in the small intestine were consistent with that observed during cellular ferroptosis, thus suggesting occurrence of ferroptosis in radiation-induced intestinal damage.