Publications by authors named "Xiaole Sun"

Menstruation is a key indicator of female reproductive health, yet clinical features and underlying mechanisms associated with menstrual changes following the coronavirus disease 2019 (COVID-19) infection remain unclear. Here, we recruited 253 participants through questionnaires, and 73 individuals underwent metabolomic analysis of blood serum. Over 60% reported menstrual changes, primarily experiencing longer cycle and lighter bleeding, which were significantly associated with age, general medical conditions, perceived stress, anxiety scores, and depression scores, as well as COVID-19 symptoms including fatigue and headache.

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Improving the energy release and safety of composite solid propellants is a key focus in energetic materials research. Graphene, with its excellent thermal conductivity and lubrication properties, is a promising additive. In this study, Al@AP core-shell particles doped with graphene were prepared via an in-situ deposition method.

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Ammonium perchlorate (AP), which is the most commonly used oxidant in composite propellants, plays a vital role in the combustion performance of propellants. In this work, by coating the AP surface with a self-assembled coating layer of gallic acid (GA) and transition metal ions (Cu or Fe) and then connecting it with a 1,1,2,2-perfluorodecyltrichlorosilane (PDTS) coating layer, the AP@GA-M@PDTS (M = Cu or Fe) composite was successfully prepared. Molecular dynamics simulation calculations show that GA and AP have a good binding ability.

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Radioactive I isotope, as one of the main products of the nuclear fission process, can be applied to track radioactive substances in the environment. So far, limited studies have investigated the spatial-temporal distribution of I in marine ecosystems including the I isotope released via nuclear activities. This study reports the I concentrations of kelps collected from the shallow coastal Yellow Sea and East China Sea from 2009 to 2021.

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Magnesium (Mg) is a key regulatory ion of N-methyl-ᴅ-aspartate (NMDA) receptors, including conferring them to function as coincidence detectors for excitatory synaptic transmission. However, the structural basis underlying the Mg action on NMDA receptors remains unclear. Here, we report the cryo-EM structures of GluN1-N2B receptors and identify three distinct Mg-binding pockets.

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Objective: Numerous studies have uncovered a correlation between menopausal, anxiety, and depressive symptoms. How these symptoms interrelate and influence each other, however, remains unclear. This study aimed to identify the associations between menopausal, anxiety, and depressive symptoms using network analysis.

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Coastal areas are an important source of methane (CH). However, the exact origins of CH in the surface waters of coastal regions, which in turn drive sea-air emissions, remain uncertain. To gain a comprehensive understanding of the current and future climate change feedbacks, it is crucial to identify these CH sources and processes that regulate its formation and oxidation.

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Purpose: Pain following costal cartilage harvest surgery is the most common complaint of auricular reconstruction (AR). Anesthesiologists are continuously searching for an effective postoperative pain control method.

Methods: This study was conducted from 10 April 2022 to 10 June 2022.

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Existing studies on the biomechanical characteristics of the first metatarsophalangeal joint (1st MTPJ) during shod running are limited to sagittal plane assessment and rely on skin marker motion capture, which can be affected by shoes wrapping around the 1st MTPJ and may lead to inaccurate results. This study aims to investigate the effects of different habitual foot strike patterns (FSP) on the six degrees of freedom (6DOF) values of the 1st MTPJ under shod condition by utilizing a dual-fluoroscopic imaging system (DFIS). Long-distance male runners with habitual forefoot strike (FFS group, = 15) and rearfoot strike (RFS group, = 15) patterns were recruited.

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In this study, the crystal appearance of industrial grade 2,6-diamino-3,5-dinitropyridine (PYX) was mostly needle-shaped or rod-shaped with an average aspect ratio of 3.47 and roundness of 0.47.

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Background: Foot kinematics, such as excessive eversion and malalignment of the hindfoot, are believed to be associated with running-related injuries. The majority of studies to date show that different foot strike patterns influence these specific foot and ankle kinematics. However, technical deficiencies in traditional motion capture approaches limit knowledge of in vivo joint kinematics with respect to rearfoot and forefoot strike patterns (RFS and FFS, respectively).

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Coastal ecosystems can efficiently remove carbon dioxide (CO) from the atmosphere and are thus promoted for nature-based climate change mitigation. Natural methane (CH) emissions from these ecosystems may counterbalance atmospheric CO uptake. Still, knowledge of mechanisms sustaining such CH emissions and their contribution to net radiative forcing remains scarce for globally prevalent macroalgae, mixed vegetation, and surrounding depositional sediment habitats.

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Article Synopsis
  • - The study investigates the movement of the medial longitudinal arch (MLA), first metatarsophalangeal joint (MTPJ), and plantar fascia (PF) during running using advanced dual fluoroscopic imaging rather than traditional motion capture methods, which can't accurately capture foot motion.
  • - Fifteen male runners who typically run with a rearfoot strike (RFS) were assessed while running with both rearfoot and forefoot strike patterns, focusing on the kinematics of the MLA and MTPJ and the length of the PF during the stance phase of running.
  • - Results showed that switching from RFS to forefoot strike (FFS) significantly increased the range of motion in various directions for both the MLA and M
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Shoes affect the biomechanical properties of the medial longitudinal arch (MLA) and further influence the foot's overall function. Most previous studies on the MLA were based on traditional skin-marker motion capture, and the observation of real foot motion inside the shoes is difficult. Thus, the effect of shoe parameters on the natural MLA movement during running remains in question.

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Article Synopsis
  • The study examines how different footwear affects the biomechanics of the first metatarsophalangeal joint (MTPJ) during running, specifically comparing shod (wearing shoes) to barefoot conditions.
  • Using a high-speed dual fluoroscopic imaging system, researchers analyzed the joint's movement in 15 healthy male runners at a steady pace, capturing detailed 6-degree-of-freedom kinematics.
  • Key findings indicate that shoe-wearing reduced movement in certain directions, altered joint angles, and potentially impacts the joint's propulsion ability, highlighting a possible increased risk for conditions like hallux valgus.
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Article Synopsis
  • Coastal methane emissions significantly impact the global methane budget and can limit the carbon storage potential of coastal ecosystems, but current estimates are unreliable due to insufficient high-resolution and long-term data.
  • Research shows that methane concentrations in coastal habitats vary widely across meter-scales and fluctuate over time, exhibiting extreme variations and unique seasonal and daily patterns depending on habitat type.
  • To accurately assess methane emissions and variability, about 50 measurement samples per day are necessary; the study emphasizes that previously overlooked northern temperate coastal areas are essential sources of atmospheric methane, especially during summer months.
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  • Phytolith carbon sequestration is vital for combating climate change over long periods, but previous estimates of its storage in China's grasslands were uncertain due to varied data sources.
  • This study involved a comprehensive field investigation across 79 sites in China, measuring phytolith-occluded carbon (PhytOC) in grasslands, revealing a decline in carbon levels from Northeast to Southwest, with the Tibetan Plateau contributing over 70% of PhytOC storage.
  • Findings indicated that factors like altitude and soil texture significantly affect PhytOC distribution, with 45% of storage found in deeper soil layers (50-100 cm), providing improved data for global carbon models and ecological restoration efforts.
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Foot and ankle joints are complicated anatomical structures that combine the tibiotalar and subtalar joints. They play an extremely important role in walking, running, jumping and other dynamic activities of the human body. The kinematic analysis of the foot and ankle helps deeply understand the movement characteristics of these structures, as well as identify abnormal joint movements and treat related diseases.

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The technical deficiencies in traditional medical imagining methods limit the study of ankle biomechanics. A dual fluoroscopic imaging system (DFIS) provides accurate and non-invasive measurements of dynamic and static activities in joints of the body. This approach can be used to quantify the movement in the single bones of the ankle and analyse different morphological and complex bone positions and movement patterns within these organs and has been widely used in the field of image diagnosis and evaluation of clinical biomechanics.

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Coastal zones are transitional areas between land and sea where large amounts of organic and inorganic carbon compounds are recycled by microbes. Especially shallow zones near land have been shown to be the main source for oceanic methane (CH) emissions. Water depth has been predicted as the best explanatory variable, which is related to CH ebullition, but exactly how sediment methanotrophs mediates these emissions along water depth is unknown.

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Although the role of shoe constructions on running injury and performance has been widely investigated, systematic reviews on the shoe construction effects on running biomechanics were rarely reported. Therefore, this review focuses on the relevant research studies examining the biomechanical effect of running shoe constructions on reducing running-related injury and optimising performance. Searches of five databases and Footwear Science from January 1994 to September 2018 for related biomechanical studies which investigated running footwear constructions yielded a total of 1260 articles.

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Purpose: This study aimed to explore the effect of fatigue on the biomechanical contribution of the lower extremity joints during a typical stretch-shortening cycle (SSC) task.

Methods: 15 male athletes completed drop jump (DJ) under pre- and post-fatigue. Vicon motion capture system and 3D Kistler force plates were used to collect kinematics and ground reaction force data simultaneously.

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In this paper, we propose a unified field-programmable gate array (FPGA) structure for a rate-adaptive forward error correction (FEC) scheme based on spatially coupled (SC) LDPC codes derived from quasi-cyclic (QC) LDPC codes. We described the unified decoder structure in detail and showed that the rate adaptation can be achieved by a controller on-the-fly. By FPGA based emulation, the results show that, with comparable complexity, the SC codes provide larger coding gain.

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The aim of this study was to determine the effects of two fatigue protocols on lower-limb joint mechanics, stiffness and energy absorption during drop landings. Fifteen male athletes completed landing tasks before and after two fatigue protocols (constant speed running [R-FP] and repeated shuttle sprint plus vertical jump [SJ-FP]). Sagittal plane lower-limb kinematics and ground reaction forces were recorded.

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In this paper, we proposed a class of large-girth QC-LDPC codes designed to maximize the girth property with code rates ranging from 0.5 to 0.8, which leads to well-structured parity-check matrix and generator matrix.

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