Individualized transcranial direct current stimulation combined with foot core exercise improves foot and ankle sensorimotor function and static postural control in individuals with chronic ankle instability.

Objective: This study aimed to investigate the effects of four-week individualized transcranial direct current stimulation (tDCS) combined with foot core exercise (FCE) on foot and ankle sensorimotor function and postural control in individuals with chronic ankle instability (CAI).

Methods: Thirty-four CAI individuals were randomly assigned to a tDCS combined with FCE group (tDCS group, n = 17) and a sham stimulation combined with FCE group (control group, n = 17). All participants received individualized stimulation combined with FCE and sham stimulation combined with FCE, respectively, three times a week for 20 min per session over four weeks.

A study on the miscibility mechanisms and patterns of high CO content associated gas reinjection.

To investigate the enhanced oil recovery mechanisms during the reinjection of CO-rich associated gas, analyse the miscibility behaviour between associated gas and crude oil, and provide guidance for increasing oil recovery in field development, in this study, gas injection expansion experiments, solubility measurements of various gases in crude oil, and slim tube experiments were conducted. The experimental results demonstrated that CH and N could reduce the solubility of associated gas in crude oil. The solubility of associated gas without CH and N in crude oil was 1.

Fluctuations and Correlations of Quark Spin in Hot and Dense QCD Matter.

In this Letter, we examine the impact of QCD phase transitions on the quark spin fluctuations and correlations. We propose the quark-antiquark correlation, which relates to the vector meson spin alignment and the Λ-Λ[over ¯] correlation, and can be used as a novel probe of the critical end point (CEP) in the QCD phase diagram. Using the Nambu-Jona-Lanisio model, we qualitatively study the properties of quark-antiquark spin correlations.

Clinical changes of cardiac function from high altitude returning to plain.

The clinical feature of cardiac functions in the areas of high altitude and plain still remains unclear. The present study intends to explore the changes of cardiac enzymes and echocardiography in population from high altitude to plain. Medical examinations were performed in a group of young male migrants who worked at high altitude of 4,888 or 5,418 m and returned to the plain of 400 m.

Orbital-Level Electronic Modulation of MnO via Interfacial Built-In Electric Fields: Breaking the Jahn-Teller Distortion Cycle for Ultra-Durable Hybrid Capacitive Deionization.

Manganese dioxide (MnO) is widely recognized as a promising electrode material for hybrid capacitive deionization (HCDI) owing to its high theoretical specific capacity and low cost. However, its practical deployment is severely constrained by Mn-induced Jahn-Teller (J-T) lattice distortions and associated disproportionation reactions, which lead to structural degradation and Mn dissolution. Here, these limitations are overcome by constructing a WS@MnO heterostructure, in which a built-in electric field is introduced at the heterogeneous interface.

Effects of Multisession High-Definition Transcranial Direct Current Stimulation on Resting-State Brain Network Connectivity and Efficiency Under Running-Induced Fatigue.

This study aimed to investigate the effects of five-session high-definition transcranial direct current stimulation (HD-tDCS) on resting-state brain network connectivity and efficiency under running-induced fatigue. This double-masked, randomized, and sham-controlled study involved 24 male adults randomly assigned to the HD-tDCS or sham-tDCS group. Participants completed a running-induced fatigue protocol at a personalized running speed before and after the intervention, and heart rate (HR) and Borg rating of perceived exertion (RPE) were monitored.

Chronic hypoxia-induced upregulation of hsa_circ_0005255 attenuates myocardial injury via targeting hsa-miR-3916/FTO/m6A axis.

Chronic hypoxia initiates compensatory mechanisms to protect the heart. Circular RNAs (circRNAs), a recently identified class of non-coding RNAs, represent a significant portion of mammalian transcriptome. We aimed to explore the underlying mechanisms of circRNA involvement in chronic hypoxia-related cardiovascular diseases.

An MRI-Compatible System for Characterizing Supraspinal Processing of Walking-Related Foot-Sole Somatosensory Stimulation.

Foot soles are the only part in direct contact with the ground during walking. The mechanoreceptors on foot soles continuously obtain somatosensory information (e.g.

Lattice Distortion Broadens the e Band of CoO to Facilitate p-d Hybridization for Enhanced Electrochemical Nitrate Synthesis.

The electrochemical nitrogen oxidation reaction (NOR) presents a sustainable pathway for nitrate synthesis under mild conditions; however, the process is hindered by the inadequate adsorption and activation of N on electrocatalysts. In this study, we utilized CoO as a model catalyst and engineered lattice distortions by introducing oxygen vacancies, which expanded the e band of the active sites to enhance N activation. The modified CoO catalyst achieved a Faradaic efficiency of 10.

Universality of pseudo-Goldstone damping near critical points.

Real-time dynamics of strongly correlated systems, in particular its critical dynamics near phase transitions, have been always on the cutting edge of studies in diverse fields of physics, e.g., high energy physics, condensed matter, holography, etc.

Running-induced fatigue influences lower extremity muscle synergy and related biomechanics.

Background: Fatigue changes muscle activation patterns as an adaptation strategy in multi-joint movements. However, due to groups of muscles involved in running, the across-muscle neurological regulation before and after fatigue is unclear. The central nervous system may employ low-dimensional modular structures, known as muscle synergies, to describe the muscle coordination in a multi-joint movement such as running.

Stabilization of Cu Sites in CuO-PdO Heterostructures via Orbital Engineering for Enhanced Electrochemical CO Reduction to Ethylene.

Electrochemical CO reduction to multicarbon products is vital for renewable fuels. While copper catalysts are effective for C production, the instability of Cu species hinders long-term performance. The present study reports the development of a CuO-PdO heterojunction and investigates the influence of an unoccupied orbital energy level regulation strategy on the stabilization of interfacial crystalline CuO during the CO reduction reaction (CORR).

Overcoming Interfacial Hydrogen Site-Blocking during Alkaline Formate Oxidation: Insights from Lattice-Compressed PdZr/C Catalysts.

Improving the electrocatalytic conversion of formate in alkaline solutions is crucial for the commercial application of formate fuel cells. However, palladium-based catalysts used for formate oxidation reactions (FOR) face challenges due to the strong adsorption of hydrogen intermediates, resulting in lower catalytic efficiency in alkaline environments. Herein, we prepared a PdZr/C catalyst aimed at employing a doping-induced strain strategy to reduce the hydrogen binding energy of palladium and release more active sites for the oxidation of formate.

Effects of shoe bending stiffness on the coordination variability of lower extremities in alternating jump rope skipping.

This study aimed to investigate how different longitudinal bending stiffness (LBS) in jump rope shoes affect the coordination variability of lower extremity segments and athletic performance during alternating jump rope skipping (AJRS). Thirty-two elite male athletes performed 30-s AJRS tasks wearing shoes with LBS measured at 3.1 Nm/rad (no-carbon-fibre-plate jump rope shoes, NS), 5.

Tumor immune microenvironment of colorectal cancer identifies novel prognostic signature and potential therapeutic drugs.

The tumor microenvironment (TME) is increasingly recognized as a key player in colorectal cancer biology, however, its potential for improving diagnosis, prognosis, and treatment remains unclear. The major aim of this study is to explore the prognostic value of TME related gene in colorectal cancer. Expression matrices and clinical data of colorectal cancer obtained from public databases were divided into TME relevant clusters according to immune characterization.

Motor control performance-related modulation of beta-band EEG-sEMG coherence differs between general and local muscular exercise-induced fatigue.

Purpose: Exercise-induced fatigue can reduce motor control performance and increase the risk of sporting injuries, which are related to functional coupling within the corticomotoneuronal pathway. However, the differences in functional coupling caused by general and local muscular exercise-induced fatigue are unknown. This study aimed to investigate the effects of exercise-induced fatigue on the beta-band (16-30 Hz) functional coupling between the sensorimotor cortex (SM1) and muscles of the dominant lower limb under different fatigue protocols.

Underwater target classification based on the combination of dolphin click trains and convolutional neural networks.

Sonar remains a major way to detect and discriminate underwater targets by interpreting the echoes. In this study, we used broadband dolphin clicks to detect and classify targets. The peak and notch features of the echo spectra were coded, and echoes were obtained using five-click trains, with the number of clicks changing from 1 to 50.

Exploring the directivities of whistle in the Indo-Pacific humpback dolphin (Sousa chinensis) and their dependency on the whistles' frequency contour.

Directional communication plays a pivotal role in enabling odontocetes to maintain group coordination and social interactions. The fundamental frequency, number of harmonics, and their relative energy distribution in whistles exhibit temporal variation. This study investigated the whistles produced by the Indo-Pacific humpback dolphins (Sousa chinensis) in Xiamen Bay, China.

Efficacy and safety of anticoagulants on venous thromboembolism: a systematic review and network meta-analysis of randomized controlled trials.

Background: Anticoagulants are the primary means for the treatment and prevention of venous thromboembolism (VTE), but their clinical standardized application still remains controversial. The present study intends to comprehensively compare the efficacy and safety of various anticoagulants in VTE.

Methods: Medline, Embase, and Cochrane Library from their inception up to August 2023 were searched to compare the efficacy and safety of various anticoagulants in VTE.

The development of deep convolutional generative adversarial network to synthesize odontocetes' clicks.

Odontocetes are capable of dynamically changing their echolocation clicks to efficiently detect targets, and learning their clicking strategy can facilitate the design of man-made detecting signals. In this study, we developed deep convolutional generative adversarial networks guided by an acoustic feature vector (AF-DCGANs) to synthesize narrowband clicks of the finless porpoise (Neophocaena phocaenoides sunameri) and broadband clicks of the bottlenose dolphins (Tursiops truncatus). The average short-time objective intelligibility (STOI), spectral correlation coefficient (Spe-CORR), waveform correlation coefficient (Wave-CORR), and dynamic time warping distance (DTW-Distance) of the synthetic clicks were 0.

The effect of anti-pronation and anti-supination taping on neuromuscular control in recreational athletes with Achilles Tendinopathy: A randomized controlled cross-over trial.

Objectives: To investigate the effects of different directions of athletic taping on neuromuscular control of the lower limb in recreational athletes with Achilles tendinopathy (AT).

Design: Crossover Study.

Setting: Functional assessment laboratory.

Effects of habitual foot strike patterns on patellofemoral joint and Achilles tendon loading in recreational runner.

Background: Most running biomechanics studies have focused on either the patellofemoral joint (PFJ) or Achilles tendon (AT) alone, generating fragmented understanding of how these structures interact as components of an integrated kinetic chain during running. This study was to investigate concurrent biomechanical changes in the PFJ and AT in recreational runners.

Methods: The recreational runners who are accustomed to run with rearfoot strike (RFS, n = 15) and forefoot strike (FFS, n = 15) patterns were recruited.

Cortical Activation during Dorsi-Plantarflexion Tasks and Its Association with Sensorimotor Function in Ankle Instability.

Objective: This study aimed to investigate differences in cortical activation between individuals with and without chronic ankle instability (CAI) during a dorsi-plantarflexion task and further explore its association with sensorimotor function.

Methods: In this cross-sectional study, 62 participants were recruited, including 31 adults with CAI and 31 healthy adults. Sensorimotor functions, including joint position sense and force sense, were tested using absolute error associated with joint position reproduction and force reproduction tasks.

Mechanisms and cross-talk of regulated cell death and their epigenetic modifications in tumor progression.

Cell death is a fundamental part of life for metazoans. To maintain the balance between cell proliferation and metabolism of human bodies, a certain number of cells need to be removed regularly. Hence, the mechanisms of cell death have been preserved during the evolution of multicellular organisms.

The Effect of Transcranial Direct Current Stimulation on Lower-Limb Endurance Performance: A Systematic Review.

This study systematically reviews the literature on transcranial direct current stimulation (tDCS) interventions for lower-limb endurance performance in healthy adults and provides a summary of the effects and underlying mechanisms of tDCS on lower-limb endurance performance. Systematic searches were performed in PubMed, Web of Science, EBSCO, and ScienceDirect. The risk of bias was assessed using the Cochrane risk of bias assessment tool.