[Psychological status-based early risk warning combined with multidisciplinary team intervention improves satisfaction of the outpatients in the andrology clinic HUANG Xun-mei1, MENG Ping1, LI Hui2, HE Wei-xiang1, MA Xiao-li3, GAO Jing-jing4, XUE Rui-zhi1, CHENG Rui1].

Objective: To investigate the psychological status of the outpatients in the andrology clinic and the effect of risk warning combined with multidisciplinary team (MDT) intervention on their satisfaction.

Methods: Using convenience sampling, we enrolled 600 outpatients seeking medical attention in the Department of Andrology of our hospital from July to October 2022. We randomized the patients into a control (n = 300) and an observation group (n = 300), obtained their basic information, evaluated their psychological status with the Hospital Anxiety and Depression Scale (HADS), and assessed their satisfaction with the Xijing Hospital Outpatients' Satisfaction Questionnaire (HOSQ).

RNA Binding Protein YTHDF2 Inhibits Synovial Fibroblast Inflammation and Bone Injury in Rheumatoid Arthritis by Reducing the mRNA Stability of IL-6R.

This study examined YTHDF2's role in modulating IL-6R signaling to regulate synovial fibroblast inflammation and bone damage in rheumatoid arthritis (RA). Synovial tissues of RA patients were collected. Human fibroblast-like synoviocyte (FLS), MH7A cell line, was induced with TNF-α and transfected.

[Family Studies of a New Allele of the B subtype (c.803G>T, p.Gly268Val)].

Objective: To analyze the B subtype gene mutation and its genetic mechanism in a family line.

Methods: ABO blood groups were identified by serologic tests. genotyping was performed by polymerase chain reaction with sequence-specific primer (PCR-SSP).

Systematic review of natural coumarins in plants (2019-2024): Chemical structures and pharmacological activities.

Coumarins constitute one of the most substantial classes of secondary metabolites, characterised by a fundamental α-benzopyranone skeleton, which serves as an overarching nomenclature for o-hydroxycinnamyl lactone moieties. These chemical constituents are widely distributed in various plant species. Based on the nature and loci of their substituents, these compounds can be further classified into simple coumarins, furanocoumarins, pyranocoumarins, isocoumarins, biscoumarins and other coumarins.

The Microbial Diversity of Biological Moss Crust: Application in Saline-Alkali Soil Management.

Soil salinization poses a substantial threat to global food security, particularly under the influence of climate change, and is recognized as one of the most urgent challenges in land degradation. This study aims to elucidate the challenges associated with managing arid and semi-arid saline-alkali lands in China's Ningxia province and propose feasible solutions. To assess moss crust colonization, we measured changes in organic matter and chlorophyll levels.

Two new sesquiterpenes from .

Two new sesquiterpenes ( and ) together with seven known compounds (-) were isolated from the whole plant of Hemsl. The chemical structures were established elucidated by extensive spectroscopic analysis and comparison with the literature. All compound were tested for antimicrobial activity.

Lactucin ameliorates FFA-induced steatosis in HepG2 cells by modulating mitochondrial homeostasis through the SIRT1/PGC-1α signaling axis.

Nonalcoholic fatty liver disease is a complex disease involving abnormal liver metabolism. Its strong association with metabolic dysfunction has led to a change in nomenclature to metabolism dysfunction-associated fatty liver disease (MAFLD). MAFLD pathogenesis involves abnormal accumulation of hepatic lipids that lead to the production of excess free fatty acids (FFAs), which in turn cause an imbalance in hepatic mitochondrial function.

Clinical intervention effect of Xuefu Zhuyu decoction on chronic heart failure complicated with depression.

Background: The diagnosis and treatment of depression in patients with chronic heart failure (CHF) is challenging, with no ideal treatment at present.

Aim: To analyze the clinical intervention effect of Xuefu Zhuyu decoction (XFZYD) on CHF complicated with depression.

Methods: The study cohort comprised 116 patients with CHF complicated with depression who received treatment from July 2020 to July 2023, of which 55 received Western medicine (control group) and 61 received XFZYD (research group).

Cistadesertosides B-E, Four New Diastereomeric Lignan Glycosides from the Stems of Cultural Cistanche deserticola in Tarim Desert.

Four previously undescribed diastereomeric lignan glycosides, namely cistadesertosides B-E (1-4) were isolated from the stems of cultural Cistanche deserticola in Tarim desert. The structures of these compounds were elucidated on the basis of extensive spectroscopic analyses, including IR, HR-ESI-MS, 1D and 2D NMR, circular dichroism (CD) data and chemical degradation. The in vitro anti-inflammatory activity of the isolates was also investigated.

Development and evaluation of short-form version of the Constitution in Chinese Medicine Questionnaire: study a new and best brief instrument of Chinese medicine for health management.

Background: More efficient instruments for body constitution identification are needed for clinical practice. We aimed to develop the short-form version of the Constitution in Chinese Medicine Questionnaire (CCMQ) and evaluate for health management.

Methods: First, the short forms were developed through expert survey, classical test theory (CTT), and modern item response (IRT) based on the CCMQ.

3D microscope image acquisition method based on zoom objective.

Microscopy is being pursued to obtain richer and more accurate information, and there are many challenges in imaging depth and display dimension. In this paper, we propose a three-dimensional (3D) microscope acquisition method based on a zoom objective. It enables 3D imaging of thick microscopic specimens with continuous adjustable optical magnification.

The Effect of Microplastics-Plants on the Bioavailability of Copper and Zinc in the Soil of a Sewage Irrigation Area.

It is essential to understand the occurrence from and plant bioavailability of soil microplastics to heavy metals in soils to assess their environmental fate and risk. The purpose of this study was to evaluate the effect of different microplastic concentrations on the bioavailability of copper and zinc in soil. The relationship between the availability of heavy metals in soil assessed by chemical methods (soil fractionation) and the bioavailability of copper and zinc assessed by biological methods (accumulation in maize and cucumber leaves) in relation to the concentration of microplastics.

Small intestinal angiosarcoma on clinical presentation, diagnosis, management and prognosis: A case report and review of the literature.

Background: Angiosarcoma is a highly malignant soft-tissue sarcoma derived from vascular endothelial cells that mainly occurs in the skin and subcutaneous tissues. Small-intestinal angiosarcomas are rare, and the prognosis is poor.

Case Summary: We reported a case of primary multifocal ileal angiosarcoma and analyze previously reported cases to improve our understanding of small intestinal angiosarcoma.

Depth of field and resolution-enhanced integral imaging display system.

Depth of field (DOF) and resolution are mutually restricted in integral imaging (II) display. To overcome the trade-offs, we propose an II display system that simultaneously enhances the DOF and resolution. The system consists of a transmissive mirror device (TMD), a semi-transparent mirror (STM), and two II display units.

NORAD promotes multiple myeloma cell progression via BMP6/P-ERK1/2 axis.

Multiple myeloma (MM) is one of the most common tumors of the hematological system and remains incurable. Recent studies have shown that long noncoding RNA NORAD is a potential oncogene in a variety of tumors. However, the general biological role and clinical value of NORAD in MM remains unknown.

System to eliminate the graininess of an integral imaging 3D display by using a transmissive mirror device.

We propose a system to eliminate the graininess of an integral imaging 3D display by using a transmissive mirror device (TMD). The proposed system consists of a 2D display, a micro-lens array (MLA), and a TMD. The TMD comprises square apertures with mirror-reflective inner wall.

Malignant histiocytosis associated with mediastinal germ cell tumor: A case report.

Background: Germ cell tumors (GCTs) account for 2% of human malignancies but are the most common malignant tumors among males aged 15-35. Since 1983, an association between mediastinal GCT (MGCT) and hematologic malignancies has been recognized.

Case Summary: We report a case in which malignant histiocytosis was associated with mediastinal GCTs.

Integrin-linked kinase affects the sensitivity of esophageal squamous cell carcinoma cells to chemotherapy with cisplatin via the Wnt/beta-catenin signaling pathway.

Recent studies have shown that the expression of integrin-linked kinase (ILK) was related to the occurrence, development, and malignant progression of esophageal squamous cell carcinoma (ESCC). However, research on the relationship between ILK and the chemosensitivity of ESCC has to date not been reported. The present study found that ILK was highly expressed in ESCC cell lines, and the overexpression of ILK in ESCC cells reduced the incidence of cell apoptosis and alleviated the cytotoxicity on cells induced by cisplatin (CDDP).