Trimetal-Organic Framework-Derived Diatomic Nanozymes-Driven Cascaded Signal Sensitization Intelligent Flexible Sensors for In Situ Detection of the Pesticide Residue.

Specific in situ detection of pesticide residues is crucial for environmental safety and scientific pesticide management. Here, we developed a portable cascade signal sensitization intelligent flexible sensor using trimetal-organic framework-derived Pt-Cu diatomic nanozymes (PtCu@TriMOF). The PtCu@TriMOF reduces the HO reduction energy barrier via cocatalysis, oxidizing TMB to generate dual-mode signals: colorimetric and photothermal.

SDA-Net: A Global Feature Point Cloud Completion Network Based on Serialization and Dual Attention.

Point cloud completion is essential for restoring 3D geometric data lost due to occlusions or sensor limitations. Existing methods often rely on k-nearest neighbor(KNN)-based local feature extraction, which focuses on neighborhoods around central points while neglecting critical global structural information. Additionally, Transformer-based approaches, while effective at modeling global context, typically use central point feature sequences to reduce computational complexity.

Comparative Genomics Reveals Evidence of the Genome Reduction and Metabolic Potentials of Isolated from Challenger Deep Sediment of the Mariana Trench.

Hadal zones account for the deepest 45% of oceanic depth range and play an important role in ocean biogeochemical cycles. As the least-explored aquatic habitat on earth, further investigation is still required to fully elucidate the microbial taxonomy, ecological significance, metabolic diversity, and adaptation in hadal environments. In this study, a novel strain Lsc_1132 was isolated from sediment of the Mariana Trench at 10,954 m in depth.

[DDX5-Targeting Fragile X Mental Retardation Protein Regulates the Wnt/β-catenin Signaling Pathway to Promote Epithelial Mesenchymal Transition in Breast Cancer].

Objective: To investigate the role of fragile X mental retardation protein (FMRP) in promoting cell migration and epithelial-mesenchymal transition (EMT) in breast cancer (BC) and the potential mechanisms involved.

Methods: The mRNA and protein expressions of FMRP in MCF-10A, a normal human breast epithelial cell line, and four breast cancer cell lines, including MCF-7, BT474, MDA-MB-231, and HCC1937, were analyzed by RT-PCR and Western blot. The expression of FMRP in BC tissues was measured by immunohistochemistry (IHC).

A vast repertoire of secondary metabolites potentially influences community dynamics and biogeochemical processes in cold seeps.

In deep-sea cold seeps, microbial communities thrive on the geological seepage of hydrocarbons and inorganic compounds, differing from photosynthetically driven ecosystems. However, their biosynthetic capabilities remain largely unexplored. Here, we analyzed 81 metagenomes, 33 metatranscriptomes, and 7 metabolomes derived from nine different cold seep areas to investigate their secondary metabolites.

Genome-based reclassification of Hussain . 2016 as a later heterotypic synonym of Cha . 2014.

YIM F302 was compared with N5 to examine the taxonomic relationship between the two type strains. The 16S rRNA gene sequence of YIM F302 showed high similarity (99.9 %) to that of N5.

Anaerobic degradation of organic carbon supports uncultured microbial populations in estuarine sediments.

Background: A large proportion of prokaryotic microbes in marine sediments remains uncultured, hindering our understanding of their ecological functions and metabolic features. Recent environmental metagenomic studies suggested that many of these uncultured microbes contribute to the degradation of organic matter, accompanied by acetogenesis, but the supporting experimental evidence is limited.

Results: Estuarine sediments were incubated with different types of organic matters under anaerobic conditions, and the increase of uncultured bacterial populations was monitored.

In situ diversity of metabolism and carbon use efficiency among soil bacteria.

The central carbon (C) metabolic network harvests energy to power the cell and feed biosynthesis for growth. In pure cultures, bacteria use some but not all of the network's major pathways, such as glycolysis and pentose phosphate and Entner-Doudoroff pathways. However, how these pathways are used in microorganisms in intact soil communities is unknown.

High-Temperature Phase Transition Containing Switchable Dielectric Behavior, Long Fluorescence Lifetime, and Distinct Photoluminescence Changes in a 2D Hybrid CuBr Perovskite.

A novel organic-inorganic hybrid perovskite crystal, [ClCH(CH)NH]CuBr (), having experienced an invertible high-temperature phase transition near (the Curie temperature = 355 K), has been successfully synthesized. The phase-transition characteristics for compound are thoroughly revealed by specific heat capacity (), differential thermal analysis, and differential scanning calorimetry tests, possessing 16 K broad thermal hysteresis. Multiple-temperature powder X-ray diffraction analysis further proves the phase-transition behavior of compound .

[Variation Characteristics and Source Analysis of Carbonaceous Aerosols in Winter in Jiashan].

Organic carbon (OC), elemental carbon (EC), and PM concentration data obtained from Shanxi Super Station in Jiashan County of Jiaxing City, in the winter of 2018 and 2019, were analyzed to determine the variation and potential source areas of carbonaceous aerosols. The results show that OC concentrations in the winter of 2018 and 2019 were 6.90 μg·m and 5.

Production of a Strain-Measuring Device with an Improved 3D Printer.

A traditional strain measurement sensor needs to be electrified and is susceptible to electromagnetic interference. In order to solve the fluctuations in the analog electrical signal in a traditional strain gauge operation, a new strain measurement method is presented here. It uses a photographic technique to display the strain change by amplifying the change of the pointer displacement of the mechanism.

Endoscopic resection of the pancreatic tail and subsequent wound healing mechanisms in a porcine model.

Background: Laparoscopic resection of the pancreatic body and tail is the predominant methodology to remove lesions in these locations; its safety and surgical planning are relatively mature, but it remains a complex and high-precision surgical operation, requiring abundant experience and skills in laparoscopic surgery, with a 10% rate of complications.

Aim: To verify the feasibility and safety, as well as to examine the complications of endoscopic pancreatectomy and healing mechanisms of pancreatic wounds after endoscopic resection.

Methods: Transgastric endoscopic resections of varying sizes of pancreases were performed in 15 healthy Bama miniature pigs.

CO conversion to methane and biomass in obligate methylotrophic methanogens in marine sediments.

Methyl substrates are important compounds for methanogenesis in marine sediments but diversity and carbon utilization by methylotrophic methanogenic archaea have not been clarified. Here, we demonstrate that RNA-stable isotope probing (SIP) requires C-labeled bicarbonate as co-substrate for identification of methylotrophic methanogens in sediment samples of the Helgoland mud area, North Sea. Using lipid-SIP, we found that methylotrophic methanogens incorporate 60-86% of dissolved inorganic carbon (DIC) into lipids, and thus considerably more than what can be predicted from known metabolic pathways (~40% contribution).

Growth of sedimentary on lignin as an energy source.

Members of the archaeal phylum are among the most abundant microorganisms on Earth. Although versatile metabolic capabilities such as acetogenesis, methanogenesis, and fermentation have been suggested for bathyarchaeotal members, no direct confirmation of these metabolic functions has been achieved through growth of in the laboratory. Here we demonstrate, on the basis of gene-copy numbers and probing of archaeal lipids, the growth of subgroup Bathy-8 in enrichments of estuarine sediments with the biopolymer lignin.

Acellular dermal matrix for esophageal stricture prevention after endoscopic submucosal dissection in a porcine model.

Background And Aims: Endoscopic submucosal dissection (ESD) is considered an effective treatment for early esophageal cancer and precancerous lesions. Esophageal stenosis is closely associated with quasi-circumferential ESD. We examined whether post-ESD esophageal stricture can be prevented by grafting an acellular dermal matrix (ADM) membrane.

High response speed microfluidic ice valves with enhanced thermal conductivity and a movable refrigeration source.

Due to their ease of fabrication, facile use and low cost, ice valves have great potential for use in microfluidic platforms. For this to be possible, a rapid response speed is key and hence there is still much scope for improvement in current ice valve technology. Therefore, in this study, an ice valve with enhanced thermal conductivity and a movable refrigeration source has been developed.

Diagnosis of lymphoma by endoscopic ultrasound-assisted transendoscopic direct retroperitoneal lymph node biopsy: A case report (with video).

Since its introduction in the early 1990s, endoscopic ultrasound-assisted fine-needle aspiration (EUS-FNA) has been used for sampling of extraintestinal mass lesions and peri-intestinal lymphadenopathy. Although EUS-FNA is highly accurate, lymphomas can be challenging to diagnose using EUS-FNA. We present the case of a 60-year-old male who had experienced upper abdominal discomfort for 1 month.

Spatial and temporal variability of polycyclic aromatic hydrocarbons in sediments from yellow river-dominated margin.

Polycyclic aromatic hydrocarbons (PAHs) were analyzed for surface sediments and a sediment core from the Yellow River-dominated margin. The concentration of 16 USEPA priority PAHs in surface sediments ranged from 5.6 to 175.

[Study on the chemical constituents of Cudrania tricuspidata].

Objective: To study on the chemical constituents of Cudrania tricuspidata.

Methods: The chemical constituents were separated by means of silica gel and Sephadex LH-20 chromatography, and their structures were identified by spectra of 1H-NMR, 13 C-NMR.

Results: Seven compounds were isolated and identified as Quercetin (I),5,7,4'-trihydroxyldihydroisoflavone (II), (13alpha, 14beta, 17alpha, 20R)-Lanosta-7, 24-diene-3beta-ol (III), (13alpha, 14beta,17alpha, 20R)-Lanosta-7,24-diene-3beta-0-acetate (IV), Taxifolin (V), Dihydromorin (VI), Cycloartocarpin(VII).

[Value of auto-fluorescence spectrum combined with tumor markers in diagnosis of lung cancer].

To improve the diagnostic efficiency of cancer, serum fluorescence spectrum combined with tumor marker groups was proved more powerful, especially when used with mathematical evaluation model, that is, artificial neural network (ANN) modeling. ANN modeling is very suitable for the discrimination of lung cancer. ANN has evident superiority in solving nonlinear, multi-parameter and uncertain complicated problems.