[Early clinical observation of the efficacy of a three-stage traditional Chinese medicine external treatment plan for talus Bone bruises caused by acute ankle sprain].

Objective: To explore the early clinical efficacy of a three-stage external treatment with traditional Chinese medicine (TCM) in the treatment of talar bone contusion caused by acute ankle sprain.

Methods: A retrospective analysis was performed on 360 patients with primary lateral ankle sprain admitted from September 2021 to July 2024. Patients with talar bone contusion were selected based on MRI examination, and 73 cases were finally included.

Efficacy and safety of bicompartmental versus total knee arthroplasty for treating medial tibiofemoral compartment combined with patellofemoral compartment osteoarthritis: a systematic review and META-analysis.

Background: Both bicompartmental knee arthroplasty (BKA) and total knee arthroplasty (TKA) are viable treatment options for patients with osteoarthritis affecting the medial tibiofemoral and patellofemoral compartments. The efficacy and safety of both surgical procedures were assessed through a systematic review and meta-analysis.

Methods: This review was registered in the PROSPERO database and adhered to the PRISMA Statement, as well as the Cochrane Handbook for Systematic Reviews of Interventions.

Self-driven electrochemical system for struvite and energy recovery from digested wastewater: Device optimization strategy and long-term operation.

A self-driven electrochemical system (SDES) was utilized to treat anaerobic digestate wastewater, aiming to achieve wastewater resource utilization and energy generation. The efficiencies of pollutant removal, resource recovery, and energy production were enhanced by adjusting device parameters (anode area, external resistance, and electrode spacing). The high pollutant removal rates and struvite purity were achieved with the magnesium anode area of 15 cm, external resistance of 10 Ω, and electrode spacing of 10 cm.

Enhancement and manipulation of nonreciprocity via dissipative coupling.

Classical and quantum nonreciprocity have important applications in information processing due to their special one-way controllability for physical systems. In this paper we investigate the nonreciprocal transmission and quantum correlation by introducing the dissipative coupling into a linear coupling system consisting of two microdisk resonators. Our research results demonstrate that even in the case of a stationary resonator, dissipative coupling can effectively induce nonreciprocity within the system.

Clinical efficacy of arthroscopic single-bundle versus double-bundle reconstruction of the posterior cruciate ligament: a retrospective study.

Purpose: To compare the functional and clinical outcomes of knee joints in patients over a 10-year period following posterior cruciate ligament (PCL) reconstruction with single-bundle versus double-bundle.

Methods: Patients who underwent PCL reconstruction were retrospectively analyzed. Based on the surgical approach, they were divided into the single-bundle reconstruction group and the double-bundle reconstruction group.

[Distribution and Biotoxicity of Endogenous Pollutants in sp. Biochar from Different Polluted Areas].

Due to the wide sources of biomass raw materials and the lack of limits for the endogenous pollutants in biochar and their dosage, some biochar with high endogenous pollutants may be used for environmental remediation, which results in potential environmental risks. In this study, three biochars were prepared from the straws of sp. grown in clean, moderately polluted and highly polluted soils, respectively.

Circular RNA circTTBK2 facilitates non-small-cell lung cancer malignancy through the miR-873-5p/TEAD1/DERL1 axis.

The underlying mechanisms by which circular RNAs (circRNAs) regulate non-small-cell lung cancer (NSCLC) progression remain elusive. This study investigated the role of circRNA circTTBK2 in NSCLC tumorigenesis. Quantitative reverse transcriptase polymerase chain reaction analysis of circTTBK2 in NSCLC tissues and cell lines was performed.

Abdominopelvic Lymphatic Drainage Area Irradiation for Consolidative Radiotherapy of Advanced Ovarian Carcinoma: Analysis of Clinical Application Efficacy and Dosimetric Verification.

Background: The aim of the study was to evaluate the efficacy of abdominopelvic lymphatic drainage area irradiation (APLN), instead of whole abdominal radiotherapy (WART), in the consolidative radiotherapy of advanced ovarian carcinoma patients.

Methods: We conducted a retrospective analysis collecting 99 patients with locally advanced ovarian cancer treated by APLN with 45 - 50 Gy/25- 28 fractions/5-7#, instead of WART. We evaluated the clinical outcome of APLN.

Genetic polymorphisms of 66 InDel loci in the Chinese Han population.

Insertion/deletion polymorphism (InDel) genetic markers refer to insertion or deletion of DNA fragments into genomic DNA, which have advantages in the identification of degraded samples. In this study, we independently screened 66 highly polymorphic InDel markers from the dbSNP database to establish a multiplex PCR system for forensic DNA identification using next-generation sequencing system (66-plex InDels). We assessed the population genetic data among 251 Chinese Han population using this system and evaluated their potential forensic application.

Improving the biocatalytic performance of co-immobilized cells harboring nitrilase via addition of silica and calcium carbonate.

To improve nicotinic acid (NA) yield and meet industrial application requirements of sodium alginate-polyvinyl alcohol (SA-PVA) immobilized cells of Pseudomonas putida mut-D3 harboring nitrilase, inorganic materials were added to the SA-PVA immobilized cells to improve mechanical strength and mass transfer performance. The concentrations of inorganic materials were optimized to be 2.0% silica and 0.

Antiangiogenic effect of crocin on breast cancer cell MDA-MB-231.

Background: Crocin is the major chemical constituent of the Chinese herb saffron. A number of studies have indicated that crocin induces an antitumor effect by inhibiting proliferation and inducing the apoptosis of tumor cells. However, the effect of crocin on tumor angiogenesis remains unknown.

Comparisons between two methods of multifetal pregnancy reduction in women with a dichorionic triamniotic triplet pregnancy.

Objective: To compare the different pregnancy outcomes of women with a reduced dichorionic triamniotic (DCTA) triplet managed with radiofrequency ablation (RFA) or potassium chloride (KCL).

Materials And Methods: This was a retrospective cohort study. We studied 30 women of DCTA triplets managed with RFA as well as 85 managed with KCL.

High-density genetic map construction and QTL mapping of first flower node in pepper (Capsicum annuum L.).

Background: First flower node (FFN) is an important trait for evaluating fruit earliness in pepper (Capsicum annuum L.). The trait is controlled by quantitative trait loci (QTL); however, studies have been limited on QTL mapping and genes contributing to the trait.

RETRACTED: PP2ACα deficiency impairs early cortical development through inducing DNA damage in neuroprojenitor cells.

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).

Efficient biocatalytic synthesis of nicotinic acid by recombinant nitrilase via high density culture.

The constitutively expression system for P. putida nitrilase was firstly constructed to improve the nicotinic acid production and reduce the production costs. High density culture strategy was employed to enhance the biomass and nitrilase production of recombinant strain.

Significantly enhanced substrate tolerance of Pseudomonas putida nitrilase via atmospheric and room temperature plasma and cell immobilization.

The objective of the study was to enhance the substrate tolerance of Pseudomonas putida nitrilase via atmospheric and room temperature plasma (ARTP) and cell immobilization. The mutant library was constructed by ARTP and rapidly screened by an OPA-TCA microscale reaction. A mutant strain of mut-D3 was obtained and its optimum substrate concentration was improved to 150mM from 100mM.

Antibacterial steroidal alkaloids from Holarrhena antidysenteriaca.

Two new steroidal alkaloids, isoconkuressine and N-formylconessimine, together with 6 known steroidal alkaloids including conkuressine, conessine, isoconessimine, conimine, conarrhimine, and funtudienine, were isolated from the seeds of Holarrhena antidysenteriaca Wall.ex A.DC.

Compounds with inhibitory activity on peristalsis from the seeds of Holarrhena antidysenterica.

Eight compounds were isolated from the seeds of Holarrhena antidysenterica Wall.ex A.DC.

Nitrile-hydrolyzing enzyme from Meyerozyma guilliermondii and its potential in biosynthesis of 3-hydroxypropionic acid.

3-Hydroxypropionic acid (3-HP) is an important platform chemical in organic synthesis. Traditionally, 3-HP was produced by chemical methods and fermentation process. In this work, a novel enzymatic method was developed for green synthesis of 3-HP.

Construction of a catsper1 DNA vaccine and its antifertility effect on male mice.

Cation channel of sperm 1 (CATSPER1) is a unique sperm cation channel protein, and essential for sperm function and male fertility. CATSPER1 exclusively expresses in meiotic and postmeiotic spermatogenic cells, thus belongs to the spermatogenesis-specific antigen that escape central tolerance. We have previously demonstrated the immunocontraceptive potential of its transmembrane domains and pore region, and reported the antifertility effects of its B-cell epitopes on male mice.

[Ecosystem carbon exchange in Artemisia ordosica shrubland of Ordos Plateau in two different precipitation years].

Characteristics of ecosystem carbon exchange and its impact factors in Artemisia ordosica shrubland in 2011 (low precipitation) and 2012 (high precipitation), Ordos Plateau, were studied using eddy covariance methods. The results showed that the diurnal dynamics of ecosystem carbon exchange could be expressed as single-peak and double-peak curves in the two different precipitation years. In 2011, three carbon absorption peaks and three carbon release peaks of ecosystem carbon exchange presented in the growing season.

[The characteristics and risk factors for post-transplantation diabetes mellitus].

Objective: To investigate the characteristics of post-transplantation diabetes mellitus and analyze its risk factors.

Methods: Extensive survey was carried out to understand the characteristics of posttransplantation diabetes mellitus in patients who received kidney grafting from February 1984 to December 2006.

Results: Three hundred forty-four post-transplantation diabetes mellitus patients from 1872 ones after kidney grafting were found from February 1984 to December 2006.

A novel mutation (D631del) of the RET gene was associated with MEN2A in a Chinese pedigree.

Germline mutations in the RET proto-oncogene (RET gene) are well documented as the genetic causes of multiple endocrine neoplasia type 2A (MEN2A). We performed genetic analysis by direct RET gene mutation analysis in a Chinese MEN2A family and compared these results with biochemical screening tests and pathological examinations. Twenty-one exons and flanking introns of the RET gene were amplified using polymerase chain reaction (PCR).

[Mutation of the RET proto-oncogene in type 2A multiple endocrine neoplasia Chinese families and the application of pentagastrin stimulation test in diagnosis and follow-up].

Objective: To detect the mutations of RET proto-oncogene in two Chinese families with multiple endocrine neoplasia type 2A (MEN2A) and to study the clinical application of pentagastrin stimulation test in the diagnosis and follow-up of MEN2A.

Methods: In this study, there were 4 patients clinically diagnosed as MEN2A in the two pedigrees. PCR and direct gene sequencing of PCR products with an automated DNA sequencer were used to scan the entire 21 exons of RET proto-oncogene in the leukocyte DNA of 6 members of the two families.