[Early clinical observation of the efficacy of a three-stage traditional Chinese medicine external treatment plan for talus Bone bruises caused by acute ankle sprain].

Objective: To explore the early clinical efficacy of a three-stage external treatment with traditional Chinese medicine (TCM) in the treatment of talar bone contusion caused by acute ankle sprain.

Methods: A retrospective analysis was performed on 360 patients with primary lateral ankle sprain admitted from September 2021 to July 2024. Patients with talar bone contusion were selected based on MRI examination, and 73 cases were finally included.

Efficacy and safety of bicompartmental versus total knee arthroplasty for treating medial tibiofemoral compartment combined with patellofemoral compartment osteoarthritis: a systematic review and META-analysis.

Background: Both bicompartmental knee arthroplasty (BKA) and total knee arthroplasty (TKA) are viable treatment options for patients with osteoarthritis affecting the medial tibiofemoral and patellofemoral compartments. The efficacy and safety of both surgical procedures were assessed through a systematic review and meta-analysis.

Methods: This review was registered in the PROSPERO database and adhered to the PRISMA Statement, as well as the Cochrane Handbook for Systematic Reviews of Interventions.

Clinical and radiological outcomes following isolated double-bundle medial patellofemoral ligament reconstruction for patellar instability in mature and normal lower limb alignment patients: a 12-year follow-up case series.

Background: The Double Bundle Medial Patellofemoral Ligament (MPFL) Reconstruction is a reliable technique for patellar instability. Clinical studies have shown its effectiveness and reliability in minimum 5-year follow-up, however, its efficacy when it comes to more than 10 years after surgery are still unclear. This retrospective study aimed to assess the effectiveness at least 12 years postoperatively.

Knowledge mapping of core decompression in osteonecrosis of the femoral head: a bibliometric analysis.

Background: Osteonecrosis of the femoral head (ONFH), caused by disrupted blood supply leading to bone cell death and joint collapse, remains a critical orthopedic challenge. While core decompression has advanced significantly in ONFH treatment, no bibliometric analysis has mapped its research landscape.

Method: We analyzed 854 articles from the Web of Science Core Collection (1986-2023) using VOSviewer, CiteSpace, and bibliometrix.

Development and validation of radiomics model for MRI-based identification of anterior talofibular ligament injuries.

Anterior talofibular ligament (ATFL) injuries are common ankle injuries that require accurate grading for effective treatment planning. However, conventional diagnostic methods, including manual MRI interpretation, often lack objectivity and reproducibility. Radiomics, a technique that extracts quantitative features from medical images, offers a promising solution for enhancing diagnostic precision.

[Clinical observation on the efficacy of ringheaded thumb-tack needle therapy combined with tuina and active functional exercise in the treatment of neck-type cervical spondylosis].

Objectives: To explore the clinical efficacy of acupressure therapy combined with Tuina and active functional exercise in the treatment of neck-type cervical spondylosis.

Methods: Sixty patients with cervical spondylosis were randomly divided into a control group and an experimental group, with 30 cases in each group. The control group was treated with Tuina and active functional exercise.

[Expert consensus on Chinese external treatment protocol for acute external ankle ligament injury].

Acute lateral ankle ligament injuries represent a prevalent form of joint sports trauma, with their occurrence increasing alongside the expanding sports demographic. Inadequate initial management of these injuries can precipitate chronic pain, joint instability, and related complications, sometimes necessitating surgical intervention. Chinese medicine, renowned for its long history and extensive experience in treating ligament injuries, is frequently integrated with modern medical practices for a comprehensive treatment approach.

Clinical efficacy of arthroscopic single-bundle versus double-bundle reconstruction of the posterior cruciate ligament: a retrospective study.

Purpose: To compare the functional and clinical outcomes of knee joints in patients over a 10-year period following posterior cruciate ligament (PCL) reconstruction with single-bundle versus double-bundle.

Methods: Patients who underwent PCL reconstruction were retrospectively analyzed. Based on the surgical approach, they were divided into the single-bundle reconstruction group and the double-bundle reconstruction group.

[Early clinical efficacy study on the efficacy of a three-stage conservative Chinese medicine external treatment for acute lateral ankle ligament injuries].

Objective: To evaluate the clinical effect of a new three-phase Chinese medicine (CM) external treatment for acute lateral ankle ligament injuries.

Methods: From July to December 2023, 64 patients with acute lateral ankle ligament injuries were randomly assigned to receive either the new three-phase CM external treatment combined with the POLICE(protect, optimal loading, ice, compression, elevation) treatment (observation group) or the POLICE treatment (control group), with 32 cases in each group. The observation group consisted of 17 males and 15 females, with an average age of(30.

Mechanism Exploration of Euphorbia fischeriana Steud. for Liver Cancer Based on Aspartic Acid Identification in Metabolomics.

Objective: To investigate the anti-liver cancer effects and aspartic acid (Asp)-related action mechanism of Euphorbia fischeriana Steud. (Lang Du, LD).

Methods: The mice model of liver cancer was established by injection of H22 cells.

Tribulus terrestris L. induces cell apoptosis of breast cancer by regulating sphingolipid metabolism signaling pathways.

Background: Tribulus terrestris L. (TT) was initially documented in Shen-Nong-Ben-Cao-Jing and has been used for thousands of years in China as a herb to calm liver, dispel melancholy and wind, promote blood circulation, improve eyesight, and relieve itching. Moreover, it was also used to treat breast cancer in ancient China.

Frequency of osteoporosis in Chinese patients with rheumatoid arthritis: a meta-analysis.

Objective: To evaluate the current frequency of osteoporosis (OP) in Chinese patients with rheumatoid arthritis (RA) through meta-analysis.

Methods: The databases of PubMed, Web of Science, Cochrane Library, CNKI, Wan Fang, CBM, and VIP were searched for relevant literature regarding the occurrence of OP in Chinese patients with RA from January 1, 2000, to September 15, 2022. The literature was screened using inclusion and exclusion criteria, and qualifying articles were subjected to data extraction, quality evaluation, and meta-analysis using Stata 17.

[Identification of differentially expressed genes in rats and preliminary analysis in regression of vascular calcification].

Objective: To investigate the differentially expressed genes in rat in the process of regression of vascular calcification by using the suppression subtractive hybridization (SSH).

Methods: 24 SD male rats which aged 6 weeks and specific pathogen free grade were selected and randomly divided into 3 groups (n = 8): control group, calcification group and regression group respectively. Vascular calcification model (vitamin D3 plus nicotine, VDN) were made from rats in calcification group and regression group, and rats in control group were intragastric administered with normal saline and lavaged with peanut oil.

[The neurovascular anatomy and its clinical implication of the rectus femoris muscle].

Objective: The objective of this anatomic study was to investigate the intramuscular neurovascular configuration and to evaluate whether the muscle could be split into two functional units in transplantation.

Methods: Ten fresh cadavers and ten preserved cadavers were used in the study. A mixture of lead oxide, gelatin and water was injected to the femoral artery of the fresh cadaver.