Crystalline Covalent Organic Framework Paper for Sweating Disorder Disease Analysis.

Abnormal sweating is closely associated with the occurrence and progression of various serious diseases, yet quantitatively and accurately assessing sweat pore function remains challenging. In this study, a crystalline covalent organic framework (COF) paper was developed for precise sweat pore analysis of sweating disorders. The delicately designed COF system achieved high-contrast sweat-responsive color change through the doping of sweat contents while showing no response to water, greatly enhancing resistance to environmental humidity interference.

Development of a pH/Cellulase Dual-Responsive Fe-MOFs Delivery System for Targeted Control of Maize Fungal Diseases.

The iron-based metal-organic frameworks (Fe-MOFs) NH-MIL-101(Fe) (MIL) has gained widespread attention as a drug carrier material in agriculture. In this study, a multifunctional nanocomposite, MIL@A@D@C, was successfully synthesized by loading the fungicide azoxystrobin (AZOX) and immunoinducer d-cellobiose (D) onto MIL, followed by surface modification with carboxymethyl cellulose (CMC). The loading capacity of MIL was optimized by varying solvent conditions and the mass ratio of MIL to AZOX, revealing that ethanol as the reaction solvent and a MIL: AZOX mass ratio of 1:4 resulted in the highest loading efficiency (6.

Comparison of double-layered scallop-shaped anastomosis and circular stapled anastomosis in Ivor-Lewis surgery for esophageal and EGJ cancer: a retrospective cohort study.

Background: Cancers of the lower esophagus and esophagogastric junction (EGJ) are highly aggressive and have poor prognoses. Minimally invasive Ivor-Lewis surgery (MIIL) is the preferred treatment, but anastomotic leakage (AL) remains a critical complication of this procedure. In the present study, we introduce a novel double-layered scallop-shaped anastomosis (DLSSA) technique and compare its outcomes with those of circular stapled esophagogastric anastomosis (CSEA).

ATF3 Within the Interferon Signaling Pathway: A Potential Biomarker for Predicting Pathological Response to Neoadjuvant Chemoimmunotherapy.

Background: Neoadjuvant chemoimmunotherapy has achieved high downstaging and pathologic response rates in nonsmall-cell lung cancer (NSCLC), but outcomes vary significantly. Early identification of beneficiaries remains a challenge.

Methods: This study analyzed baseline transcriptomic data from 24 NSCLC patients (9 major pathological response [MPR], 15 nonmajor pathological response [NMPR]) treated with neoadjuvant chemoimmunotherapy, sourced from the GEO database.

Magnetic Nanoparticles in Agriculture: Unraveling the Impact of Nickel Ferrite Nanoparticles on Peanut Growth and Seed Nutritional Quality.

Nanotechnology has been a source of innovation in various fields in recent years, and its application in agriculture has attracted much attention, particularly for its potential to enhance crop growth and optimize nutritional quality. This study systematically investigated the effects of nickel ferrite nanoparticles (NiFeO NPs) on peanut ( L.) growth, nutrient dynamics, and biochemical responses, highlighting their potential as sustainable alternatives to conventional fertilizers.

Percutaneous coronary intervention-lobectomy for Lung Cancer hybrid surgery: an initial case series.

Background: For patients diagnosed with both lung cancer and severe coronary heart disease (CHD), the conflict between revascularization and lung cancer surgery remains to be settled to balance how to attenuate the cardiovascular risk for lung surgery and shorten the waiting time of anti-platelet therapy after revascularization. This study presents the percutaneous coronary intervention (PCI)-lobectomy for lung cancer hybrid surgery (PLHS), and its antithrombotic therapeutic strategy.

Methods: From October 2020 to June 2023, 14 patients, with unstable angina and resectable lung cancer received PLHS.

Correction: Non-linear links between human capital, educational inequality and income inequality, evidence from China.

[This corrects the article DOI: 10.1371/journal.pone.

Investigating the Underlying Molecular Mechanisms of Yunke on Bone Metastases from Prostate Cancer.

Objective: To explore analgesic effect and bone repair mechanism of non-radioactive technetium-99 conjugated with methylene diphosphonate (Tc-MDP, brand name, Yunke) on bone metastases (BM).

Procedures: In vivo experiment, mouse BM models of prostate cancer RM-1 cell were constructed and divided into Control, Yunke, Tc+SnCl and MDP groups based on medicine composition. Tumor specimens were inspected for size, X-ray, microCT and histopathology.

Simultaneous Circular Dichroism and Wavefront Manipulation with Generalized Pancharatnam-Berry Phase Metasurfaces.

Simultaneous circular dichroism and wavefront manipulation have gained considerable attention in various applications, such as chiroptical spectroscopy, chiral imaging, sorting and detection of enantiomers, and quantum optics, which can improve the miniaturization and integration of the optical system. Typically, structures with n-fold rotational symmetry ( ≥ 3) are used to improve circular dichroism, as they induce stronger interactions between the electric and magnetic fields. However, manipulating the wavefront with these structures remains challenging because they are commonly considered isotropic and lack a geometric phase response in linear optics.

Oxymatrine Modulation of TLR3 Signaling: A Dual-Action Mechanism for H9N2 Avian Influenza Virus Defense and Immune Regulation.

In our research, we explored a natural substance called Oxymatrine, found in a traditional Chinese medicinal plant, to fight against a common bird flu virus known as H9N2. This virus not only affects birds but can also pose a threat to human health. We focused on how this natural compound can help in stopping the virus from spreading in cells that line the lungs of birds and potentially humans.

Cecropin AD reduces viral load and inflammatory response against H9N2 avian influenza virus in chickens.

Introduction: This study focuses on evaluating the therapeutic efficacy of cecropin AD, an antimicrobial peptide, against H9N2 avian influenza virus (AIV) in chickens. Given the global impact of H9N2 AIV on poultry health, identifying effective treatments is crucial.

Methods: To assess the impact of cecropin AD, we conducted experiments involving 108 5-week-old chickens divided into control, infected, and various treatment groups based on cecropin AD dosage levels (high, medium, and low).

Right gastroepiploic artery length determined anastomotic leakage after minimally invasive esophagectomy for esophageal cancer: a prospective cohort study.

Background: This prospective cohort study, conducted at a high-volume esophageal cancer center from July 2019 to July 2022, aimed to investigate the link between the right gastroepiploic artery (RGEA) length and anastomotic leakage (AL) rates following minimally invasive esophagectomy (MIE). Real-world data on stomach blood supply in the Chinese population were examined.

Materials And Methods: A total of 516 cases were enrolled, categorized into two groups based on the Youden index-determined optimal cut-off value for the relative length of RGEA (length of RGEA/length of gastric conduit, 64.

Dynamic nonlinear CO2 emission effects of urbanization routes in the eight most populous countries.

A dynamic STIRPAT model used in the current study is based on panel data from the eight most populous countries from 1975 to 2020, revealing the nonlinear effects of urbanization routes (percentage of total urbanization, percentage of small cities and percentage of large cities) on carbon dioxide (CO2) emissions. Using "Dynamic Display Unrelated Regression (DSUR)" and "Fully Modified Ordinary Least Squares (FMOLS)" regressions, the outcomes reflect that percentage of total urbanization and percentage of small cities have an incremental influence on carbon dioxide emissions. However, square percentage of small cities and square percentage of total urbanization have significant adverse effects on carbon dioxide (CO2) emissions.

Corporate social Responsibility's impact on passenger loyalty and satisfaction in the Chinese airport industry: The moderating role of green HRM.

Corporate social responsibility has been extensively discussed and linked to the firm performance by the researchers. However, a significant research gap remains unexplored and that is measuring the association between corporate social responsibility, passenger satisfaction, and loyalty in the context of two international airports in China. This research also measures the moderating impact of green human resources management on the relationship between CSR, passengers' satisfaction, and loyalty.

Breakup-Free and Colorful Liquid Metal Thin Films via Electrochemical Oxidation.

Thin-film metal conductors featuring high conductivity and stretchability are basic building blocks for high-performance conformable electronics. Gallium-based liquid metals are attractive candidates for thin-film conductors due to their intrinsic stretchability and ease of processing. Moreover, the phase change nature of liquid metal provides an opportunity to create conformal electronics in a substrate-free manner.

Non-linear links between human capital, educational inequality and income inequality, evidence from China.

This study aims to reveal short-run and long-run asymmetries among human capital, educational inequality, and income inequality in China over the period 1975-2020 using a nonlinear autoregressive distributed lag (NARDL) model. The estimated long-run asymmetry parameters reflect that positive shocks to secondary education (SSE) and higher education (HE) are negatively correlated with income Gini coefficient. The adverse shocks of secondary education (SSE) and higher education (HE) stimulate the Gini coefficient of income, but the effect of secondary education (SSE) on the Gini coefficient of income is not significant, while that of higher education (HE) is significant.

Links among population aging, economic globalization, per capita CO emission, and economic growth, evidence from East Asian countries.

Population aging, economic globalization, and economic growth simultaneously cause changes in environmental quality, but so far no studies have integrated these key factors into the same environmental policy framework. Thus, this study uses the more robust Westerlund cointegration test and the augmented mean group (AMG) estimator (robust to cross-sectional dependence (CD), heterogeneity, and endogeneity) to estimate the long-term relationship between population aging, economic globalization, economic growth, and per capita carbon emissions in East Asian countries during the period 1975-2018. The analysis results reflect that population aging significantly reduces the long-term per capita carbon emissions of specific East Asian countries.

A Superior Two-Dimensional Phosphorus Flame Retardant: Few-Layer Black Phosphorus.

The usage of flame retardants in flammable polymers has been an effective way to protect both lives and material goods from accidental fires. Phosphorus flame retardants have the potential to be follow-on flame retardants after halogenated variants, because of their low toxicity, high efficiency and compatibility. Recently, the emerging allotrope of phosphorus, two-dimensional black phosphorus, as a flame retardant has been developed.

A dynamic relationship between renewable energy, agriculture, globalization, and ecological footprint of the five most populous countries in Asia.

This study aims to examine the impact of globalization, renewable energy consumption, and agricultural value addition on the ecological footprint of selected five most populous countries in Asia during the period 1975-2020. The Westerlund cointegration test supports long-term cointegration relationships among the considered variables in selected countries. The long-term resilience results of the second-generation cross-sectionally augmented autoregressive distributed lag approach evidently demonstrate that agricultural value addition and globalization contribute significantly to the long-term ecological footprint of the five most populous countries in Asia.

An empirical analysis of the impact of gender inequality and sex ratios at birth on China's economic growth.

The contribution of women to China's economic growth and development cannot be overemphasized. Women play important social, economic, and productive roles in any economy. China remains one of the countries in the world with severe gender inequality and sex ratio at birth (SRB) imbalance.

Prevalence and clinical aspects of depression in Parkinson's disease: A systematic review and meta‑analysis of 129 studies.

Depression is one of the most important non-motor symptoms in Parkinson's disease (PD), but its prevalence and related clinical characteristics are unclear. To this end, we performed a systematic review and meta-analysis based on 129 studies, including 38304 participants from 28 countries. Overall, the prevalence of depression in PD was 38 %.

Degradation Chemistry and Kinetic Stabilization of Magnetic CrI.

The discovery of the intrinsic magnetic order in single-layer chromium trihalides (CrX, X = I, Br, and Cl) has drawn intensive interest due to their potential application in spintronic devices. However, the notorious environmental instability of this class of materials under ambient conditions renders their device fabrication and practical application extremely challenging. Here, we performed a systematic investigation of the degradation chemistry of chromium iodide (CrI), the most studied among CrX families, a joint spectroscopic and microscopic analysis of the structural and composition evolution of bulk and exfoliated nanoflakes in different environments.

Dysregulation of long non-coding RNAs and their mechanisms in Huntington's disease.

Extensive alterations in gene regulatory networks are a typical characteristic of Huntington's disease (HD); these include alterations in protein-coding genes and poorly understood non-coding RNAs (ncRNAs), which are associated with pathology caused by mutant huntingtin. Long non-coding RNAs (lncRNAs) are an important class of ncRNAs involved in a variety of biological functions, including transcriptional regulation and post-transcriptional modification of many targets, and likely contributed to the pathogenesis of HD. While a number of changes in lncRNAs expression have been observed in HD, little is currently known about their functions.

Integrated analysis of differentially expressed genes and construction of a competing endogenous RNA network in human Huntington neural progenitor cells.

Background: Huntington's disease (HD) is one of the most common polyglutamine disorders, leading to progressive dyskinesia, cognitive impairment, and neuropsychological problems. Besides the dysregulation of many protein-coding genes in HD, previous studies have revealed a variety of non-coding RNAs that are also dysregulated in HD, including several long non-coding RNAs (lncRNAs). However, an integrated analysis of differentially expressed (DE) genes based on a competing endogenous RNA (ceRNA) network is still currently lacking.

Black phosphorus composites with engineered interfaces for high-rate high-capacity lithium storage.

High-rate lithium (Li) ion batteries that can be charged in minutes and store enough energy for a 350-mile driving range are highly desired for all-electric vehicles. A high charging rate usually leads to sacrifices in capacity and cycling stability. We report use of black phosphorus (BP) as the active anode for high-rate, high-capacity Li storage.