Bioinspired leaf vein-architected gold nanowire ecoflexible biosensors for ultrasensitive occlusal force monitoring.

Flexible biosensors and bioelectronics for real-time healthcare monitoring require high sensitivity and durability, yet their high-cost materials and complex fabrication often hinder clinical translation. Emerging bio-templated electronics leverage evolutionarily optimized natural architectures to overcome these synthetic limitations. Here, we harness the bioinspired, hierarchical structure of natural leaf veins to create an ecoflexible, high-performance sensor, which feature a unique hierarchical, multibranching structure that enhances both mechanical performance and sensing efficiency.

One-Step Digital Light Processing 3D Printing of Robust, Conductive, Shape-Memory Hydrogel for Customizing High-Performance Soft Devices.

Mechanically robust and electrically conductive hydrogels hold significant promise for flexible device applications. However, conventional fabrication methods such as casting or injection molding meet challenges in delivering hydrogel objects with complex geometric structures and multicustomized functionalities. Herein, a 3D printable hydrogel with excellent mechanical properties and electrical conductivity is implemented via a facile one-step preparation strategy.

Phase transition-driven encapsulation of biomolecules using liquid metal with on-demand release for biomedical applications.

Robust encapsulation and controllable release of biomolecules have wide biomedical applications ranging from biosensing, drug delivery to information storage. However, conventional biomolecule encapsulation strategies have limitations in complicated operations, optical instability, and difficulty in decapsulation. Here, we report a simple, robust, and solvent-free biomolecule encapsulation strategy based on gallium liquid metal featuring low-temperature phase transition, self-healing, high hermetic sealing, and intrinsic resistance to optical damage.

Soft Robots with Plant-Inspired Gravitropism Based on Fluidic Liquid Metal.

Plants can autonomously adjust their growth direction based on the gravitropic response to maximize energy acquisition, despite lacking nerves and muscles. Endowing soft robots with gravitropism may facilitate the development of self-regulating systems free of electronics, but remains elusive. Herein, acceleration-regulated soft actuators are described that can respond to the gravitational field by leveraging the unique fluidity of liquid metal in its self-limiting oxide skin.

Breakup-Free and Colorful Liquid Metal Thin Films via Electrochemical Oxidation.

Thin-film metal conductors featuring high conductivity and stretchability are basic building blocks for high-performance conformable electronics. Gallium-based liquid metals are attractive candidates for thin-film conductors due to their intrinsic stretchability and ease of processing. Moreover, the phase change nature of liquid metal provides an opportunity to create conformal electronics in a substrate-free manner.

Versatile sweat bioanalysis on demand with hydrogel-programmed wearables.

Wearable sweat bioanalysis is promising for non-invasive diagnostics of diseases. However, collection of representative sweat samples without disturbing daily life and wearable bioanalysis of targets that are clinically significant are still challenging. In this work, we report on a versatile method for the sweat bioanalysis.

Shape-Programmable Liquid Metal Fibers.

Conductive and stretchable fibers are the cornerstone of intelligent textiles and imperceptible electronics. Among existing fiber conductors, gallium-based liquid metals (LMs) featuring high conductivity, fluidity, and self-healing are excellent candidates for highly stretchable fibers with sensing, actuation, power generation, and interconnection functionalities. However, current LM fibers fabricated by direct injection or surface coating have a limitation in shape programmability.

Ultrahigh Polarization Response along Large Energy Storage Properties in BiFeO-BaTiO-Based Relaxor Ferroelectric Ceramics under Low Electric Field.

BiFeO-BaTiO (BF-BT) dielectric ceramics are receiving more and more concern for advanced energy storage devices owing to their excellent ferroelectric properties and environmental sustainability. However, the energy density and efficiency are limited in spite of the large remanent polarization. Herein, we proposed a multiscale optimization strategy via a local compositional disorder with a Birich content and nanodomain engineering by introducing the SrBiCaTiO (SBCT) into BF-BT ceramics.

Surface-Embedded Liquid Metal Electrodes with Abrasion Resistance Direct Magnetic Printing.

Gallium-based liquid metals (LMs) featuring both high conductivity and fluidity are ideal conductors for soft and stretchable electronics. However, their liquid nature is a double-edged sword in many key applications since LMs are inherently prone to mechanical damage. Although additional encapsulation is frequently used for the protection of delicate LM electrodes, it hinders the electrical interfacing with other objects for interconnection, sensing, and stimulation.

Widely Targeted Metabolomics Analysis of Soybean and Chickpea and Their Different Advantages and New Functional Compounds for Diabetes.

Soybean is widely used as a kind of bean for daily consumption. Chickpea is increasingly utilised because of its good healthcare function. At present, using chickpeas could have better results than soybeans in some areas.

[EGFR tyrosine kinase inhibitor HS-10296 induces autophagy and apoptosis in triplenegative breast cancer MDA-MB-231 cells].

Objective: To investigate the inhibitory effect of epidermal growth factor receptor tyrosine kinase inhibitor (EGFRTKI) HS-10296 on the proliferation of triple-negative breast cancer (TNBC) MDA-MB-231 cells and explore the possible molecular mechanism.

Methods: MDA-MB-231 cells were treated with HS-10296 for 24, 48, or 72 h, and CCK-8 assay was used to assess the changes in the cell viability. The inhibitory effect of HS-10296 on cell proliferation was determined by clonogenic assay.

Incorporation of triazacyclononane into the metal phosphonate backbones.

This paper reports the syntheses and crystal structures of a manganese and a uranyl phosphonate based on 1,4,7-triazacyclononane-1,4,7-triyl-tris(methylenephosphonic acid), namely, Mn3{C9N3H18(PO3)3}(H2O)6 x 1.5 H2O (1) and UO2{C9N3H19(PO3H)3} x H2O (2). Compound 1 shows a unique layer structure where the hydrophobic triazacyclononane moieties all reside on one side of the inorganic backbone of the manganese phosphonate layer while the hydrophilic coordinated water molecules reside on the other side.