Publications by authors named "Shi-Hui Wang"

This study systematically documented macrofungal diversity in Beijing, China (field surveys conducted from 2020 to 2024) using line-transect and random sampling. A total of 1056 species were identified, spanning 2 phyla, 7 classes, 25 orders, 109 families, and 286 genera. The inventory includes 12 new species, 456 new records for Beijing, 79 new records for China, and comprises 116 edible, 56 edible-medicinal, 123 medicinal, and 58 poisonous species.

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Renal neuroendocrine tumors (NETs) are rare due to the absence of neuroendocrine cells in the kidney. Preoperative diagnosis is challenging often leading to misdiagnosis unnecessary nephrectomy. This study retrospectively analyzed three cases of renal NETs reviewing their diagnosis treatment processes.

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Unlabelled: Horizontal gene transfer (HGT) in fungi is less understood despite its significance in prokaryotes. In this study, we systematically searched for HGT events in 829 representative fungal genomes. Using a combination of sequence similarity and phylogeny-based approaches, we detected 20,093 prokaryotic-derived transferred genes across 750 fungal genomes, via 8,815 distinct HGT events.

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The emergence of nanogenerators, which have the ability to capture mechanical energy from the environment and to collect and transmit tiny energy, is rapidly becoming a hot research topic. The performance of electrode materials is the key to the efficiency of nanogenerators. Covalent organic skeletons (COFs), a class of crystalline organic porous materials with the advantages of large specific surface area, high porosity, tunable structure, and flexible tailorability, have very significant advantages in being used as nanogenerator materials.

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  • ICAM-1 is often overexpressed in non-small cell lung cancer (NSCLC), which is linked to worse patient outcomes, but the reasons for its harmful effects are not fully understood.
  • Research shows that the survival of NSCLC cells relies on a signal from the interaction between fibrinogen γ chain (FGG) and ICAM-1, which activates survival pathways and prevents cell death.
  • By inhibiting the interaction between ICAM-1 and FGG with a developed monoclonal antibody, researchers were able to decrease NSCLC cell survival and tumor growth in experiments, suggesting a new targeted therapy approach for NSCLC.
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  • The study investigates how integrins on lymphocytes are quickly activated to facilitate their immediate arrest in response to chemokines while they are rolling through blood vessels.
  • It shows that the chemokine CCL25 causes a rapid drop in extracellular calcium levels, triggering the activation of integrin αLβ2 in T cells before the traditional inside-out activation process takes place.
  • Moreover, blocking calcium influx impairs T cell movement and their ability to home to inflamed skin in a psoriasis mouse model, suggesting that this rapid activation is crucial for effective lymphocyte function and inflammation control.
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  • Migrasomes are specialized organelles formed by migrating neutrophils and play a crucial role in blood clotting (haemostasis).
  • They are abundant in both mouse and human blood and enhance coagulation by binding coagulation factors and adhesion molecules, especially at injury sites.
  • Reducing neutrophils or migrasomes impairs blood clot formation, but injecting purified migrasomes can restore it, suggesting their importance in coagulation disorders and potential for new treatments.
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is the largest genus in the Russulales and is widespread throughout the world. Almost all species are known to be ectomycorrhizal with high ecological and edible values, and some are lethal poisonous. In this study, four new species belonging to the subgenus crown clade are identified based on morphological and phylogenetic evidence from the Xizang Autonomous Region and other provinces of China.

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Objective: To evaluate the rabbit modle of frozen shoulder induced by persistent strain injuries and ice compression.

Methods: Twelve clean, healthy male New Zealand rabbits with a mass of (2 500±500) g were selected and randomly divided into a blank group and a control group with 6 rabbits in each group. In the control group, the rabbits were modeled with persistent strain injuries and ice compression, the general conditions of the rabbits and the active and passive activities of the shoulder joint were observed and their body weights were recorded.

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  • * Researchers collected seventy-eight specimens from ten provinces in China and performed both molecular phylogenetic analysis and morphological examinations to identify the species.
  • * Eleven species were recognized, including five newly discovered ones, mainly from the Xizang Autonomous Region, highlighting their unique adaptation to this specific habitat and contributing to the understanding and conservation of fungal diversity.
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  • Wild plants, specifically D. dcne., have potential as urban landscape trees due to their ornamental value and ability to enhance urban foliage and fruit variety.
  • Researchers conducted pot experiments to find the best fertilizer application strategy, testing ten different groups, including a control.
  • The findings indicate organic fertilizer, especially at a medium level (4.06 g per plant), significantly improved seedling growth metrics like height, diameter, and chlorophyll content, highlighting its importance in seedling reproduction.
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MOF (metal organic framework) materials have been used as functional materials in a number of fields due to their diverse spatial tunability, which produces rich porous structures with stable and continuous pores and a high specific surface area. A triboelectric nanogenerator can convert trace mechanical energy into electrical energy, and the application of MOF materials to triboelectric nanogenerators has been intensively studied. In this work, we report on two MOFs with similar spatial structures, and the modulation of the end microstructures was achieved using the difference in F content.

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The emergence of nanogenerators, which provide a way to obtain mechanical energy from the environment and to collect and transmit tiny amounts of energy, has attracted a lot of attention. MOFs, because of their diverse structures as well as stable pores and large specific surface area, have very significant advantages to be used as nanogenerator materials. In this paper, two MOFs with similar spatial structures are designed to take advantage of the different coordination numbers of carboxylic acids to achieve the regulation of their microstructures.

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Background: In microsurgical tissue transfer, skin flap transplantation is frequently used to heal the surface of a wound. Effective microcirculation surveillance of the skin flap is crucial. However, with traditional monitoring methods-that is, clinical observation-vascular crisis can still occur, thereby impairing postoperative recovery.

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Dynamic regulation of integrin activation and inactivation is critical for precisely controlled cell adhesion and migration in physiological and pathological processes. The molecular basis for integrin activation has been intensively studied; however, the understanding of integrin inactivation is still limited. Here, we identify LRP12 as an endogenous transmembrane inhibitor for α4 integrin activation.

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Human pluripotent stem cell-derived cardiovascular progenitor cells (hCVPCs) and cardiomyocytes (hCMs) possess therapeutic potential for infarcted hearts; however, their efficacy needs to be enhanced. Here we tested the hypotheses that the combination of decellularized porcine small intestinal submucosal extracellular matrix (SIS-ECM) with hCVPCs, hCMs, or dual of them (Mix, 1:1) could provide better therapeutic effects than the SIS alone, and dual hCVPCs with hCMs would exert synergic effects in cardiac repair. The data showed that the SIS patch well supported the growth of hCVPCs and hCMs.

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The enoki mushroom () is one of the most important and popular edible mushrooms commercially in China. However, traditional mushroom cultivar identification is challenging due to poor accuracy, heavy workloads, and low reproducibility. To overcome this challenge, we developed a method for identifying strains using multiple nucleotide polymorphism sequencing (MNP-seq).

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Three new compounds, polygalapyrone A (), tenuiside G () and polygalapyrrole A (), together with two known compounds () were isolated by silica gel, ODS and preparative HPLC from the aerial part of . Their structures were elucidated by spectrum analysis and compared with findings from the literature. The anti-inflammatory effects of those compounds were investigated .

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  • Diabetic retinopathy (DR) is caused by retinal damage from diabetes, severely affecting vision and quality of life, making it a significant burden on individuals and society.
  • Recent studies suggest that Membranaceus (AM), a traditional Chinese medicine, may have potential in treating DR, although its exact mechanism remains unclear.
  • This research identifies 24 active compounds from AM and 38 core targets linked to its therapeutic effects on DR, indicating AM works through various pathways involved in oxidative stress, cell apoptosis, and inflammation.
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Objective: is a common pathogenic fungus in ginseng cultivation. Both pathogens and antagonistic fungi have been reported to induce plant resistance responses, thereby promoting the accumulation of secondary metabolites. The purpose of this experiment is to compare the advantages of one of the two fungi, in order to screen out more effective elicitors.

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Mitten crab (Eriocheir sensu stricto) is an indigenous and economically important species in East Asia. The genetic diversity and population structure of four wild native Eriocheir s. s.

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Fever is an evolutionarily conserved response that confers survival benefits during infection. However, the underlying mechanism remains obscure. Here, we report that fever promoted T lymphocyte trafficking through heat shock protein 90 (Hsp90)-induced α4 integrin activation and signaling in T cells.

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Ginsenosides attract great attention for their bioactivities. However, their contents are low, and many UDP-glycosyltransferases (UGTs) that play crucial roles in the ginsenoside biosynthesis pathways have not been identified, which hinders the biosynthesis of ginsenosides. In this study, we reported that one UDP-glycosyltransferase, UGTPg71A29, from Panax ginseng could glycosylate C20-OH of Rh and transfer a glucose moiety to Rd, producing ginsenosides Rg and Rb, respectively.

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Chemokine (C-C motif) ligand 25 (CCL25) and C-X-C motif chemokine 10 (CXCL10) induce the ligand-specific activation of integrin α4β7 to mediate the selective adhesion of lymphocytes to mucosal vascular addressin cell adhesion molecule-1 (MAdCAM-1) or vascular cell adhesion molecule-1 (VCAM-1). However, the mechanism underlying the selective binding of different ligands by α4β7 remains obscure. In this study, we demonstrate that CCL25 and CXCL10 induce distinct active conformers of α4β7 with a high affinity for either MAdCAM-1 or VCAM-1.

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Study Design: A three-level rat tail caudal intervertebral disc (IVD) degeneration (IVDD) model was established to study effects of static compression on extracellular matrix (ECM) remodeling and integrin signaling in IVDs during IVDD.

Objective: The aim of this study was to investigate the effect of compression force on ECM remodeling and integrin signaling in IVDs during IVDD.

Summary Of Background Data: Integrins sense mechanical environment alteration via binding to ECM ligands and trigger intracellular signaling for pathological ECM remodeling during IVDD.

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