Species Diversity and Resource Status of Macrofungi in Beijing: Insights from Natural and Urban Habitats.

This study systematically documented macrofungal diversity in Beijing, China (field surveys conducted from 2020 to 2024) using line-transect and random sampling. A total of 1056 species were identified, spanning 2 phyla, 7 classes, 25 orders, 109 families, and 286 genera. The inventory includes 12 new species, 456 new records for Beijing, 79 new records for China, and comprises 116 edible, 56 edible-medicinal, 123 medicinal, and 58 poisonous species.

Roadmap for Next-Generation Electrochemical Energy Storage Technologies: Secondary Batteries and Supercapacitors.

The transition from fossil fuels to environmentally friendly renewable energy sources is crucial for achieving global initiatives such as the carbon peak and carbon neutrality. The use of secondary batteries and supercapacitors based on electrochemical energy storage principles provides high energy density, conversion efficiency, and rapid response times, offering essential solutions for stabilizing and ensuring the reliability of energy supply from renewable sources despite their intermittency. In recent years, increased demands for higher energy density, improved rate performance, longer cycle life, enhanced safety, and cost-effectiveness have driven researchers to delve deeper into electrode materials, electrolytes, and storage mechanisms in secondary batteries.

Tunable surface potential nanomaterials for enhanced environmental nucleic acid extraction and surveillance.

Environmental nucleic acid (eNA) technology is an essential tool for public health and environmental management, including virus surveillance and antibiotic resistance gene (ARG) monitoring. However, large-scale, high-frequency eNA analysis remains challenging due to existing extraction techniques being inefficient, time-consuming, and reliant on specialized equipment. This study introduces a versatile eNA extraction approach using a reusable magnetic material with tunable surface potential (TPMP), achieving ∼90 % recovery efficiency within 60 min and demonstrating superior enrichment across various eNA forms.

Current status and advances in the treatment of colorectal cancer with liver metastases.

The incidence of colorectal cancer is gradually increasing, and a majority of patients are diagnosed with distant metastases at the time of initial diagnosis, with the liver being the most common site of metastasis. Unlike most malignant tumors, patients with distant metastases can still achieve favorable prognoses if both the primary tumor and liver metastases are surgically resected. With advances in systemic therapies, many patients with initially unresectable liver metastases from colorectal cancer can undergo systemic treatment to achieve conversion therapy, thereby gaining the opportunity for surgery.

Poor sleep quality among patients with Parkinson's disease: a meta-analysis and systematic review.

Objective: Poor sleep quality is common among patients with Parkinson's disease (PD), although the reported prevalence rates vary between studies. This meta-analysis examined the overall prevalence of poor sleep quality in patients with PD and identified potential factors contributing to the differences in prevalence across studies.

Methods: Both PRISMA and MOOSE guidelines were applied in this meta-analysis.

Mitigating hypersonic heat barrier via direct cooling enhanced by leidenfrost inhibition.

Heat barrier, the unrestricted increase in airplane or rocket speeds caused by aerodynamic heating, which-without adequate provisions for cooling the exposed surfaces-can lead to the loss of a hypersonic vehicle's reusability, maneuverability, and cost-effectiveness. To date, indirect thermal protection methods, such as regenerative cooling, film cooling, and transpiration cooling, have proven to be complex and inefficient. Here, we propose a direct liquid cooling system to mitigate the heat barrier, utilizing a blunt-sharp structured thermal armor (STA)-a recently proposed material [36] to elevate the Leidenfrost point.

High entropy compounds for electrochemical energy storage.

High entropy compounds (HECs) are a new type of multi-element material. They overcome the limitations of traditional energy storage materials. HECs achieve this through three key features: high entropy effect, lattice distortion, and element synergy.

The DRN-VLO pathway via distinct 5-HT synaptic mechanisms modulates neuropathic pain-induced depressive-like behaviors in mice.

Background: The neuronal activities within the dorsal raphe nucleus (DRN) and the ventrolateral orbital cortex (VLO) are strongly implicated in the development of depression, a condition comorbid with chronic pain. The goal of the present study was to determine whether and how the DRN-VLO pathway mediates chronic pain-induced depression.

Methods: Trigeminal neuralgia was induced unilaterally by chronic constriction injury of the infraorbital nerve.

Residential Greenness and the Incidence of Dyslipidemia in Chinese Adults: A Large Prospective Cohort Study.

Dyslipidemia is a significant risk factor for cardiovascular disease. While cross-sectional studies suggest lower odds of dyslipidemia in greener environments, longitudinal research is limited. This prospective cohort study analyzed data from 3,454,623 adults from January 2017 to December 2021, focusing on dyslipidemia and its subtypes.

Advancing Bioprinting Technology Utilizing Portable Bioprinters: From Various Device Designs to Dental Applications.

Recent advancements in portable bioprinting technology present transformative opportunities for dental applications, enabling handy fabrication of biologically functional tissues. This narrative review examines the current state of portable bioprinting systems, focusing on their potential to address critical challenges in restorative dentistry, periodontal regeneration, and endodontic therapy. We summarize key innovations in handheld bioprinting devices, emphasizing their operational mechanisms, bioink developments, and clinical applicability.

Tricin selectively combats KRAS-mutant non-small cell lung cancer by inhibiting the PDGF-BB-induced SRC/MAPK/AP-1/PD-L1 signaling pathway and potentiating the antitumor effect of an anti-PD-1 antibody.

Background: KRAS is a commonly mutated gene that is present in approximately 30% of NSCLC patients. Currently, the identification of effective therapies for KRAS-mutant NSCLC is difficult for reasons of the structural and biochemical characteristics of the KRAS protein. Our previous study has revealed that tricin was a bioactive component having selective effects on KRAS-mutant NSCLC cell lines.

Multidimensional Assessment of Psychiatric Adverse Events Related to Proton Pump Inhibitors: A Real-World, Pharmacovigilance Study.

Introduction: Limited research has been conducted on the association between proton pump inhibitors (PPIs) use and psychiatric adverse events (AEs), leaving the understanding of PPIs-related psychiatric AEs in real-world settings unclear.

Objectives: We aim to identify psychiatric AEs highly relevant to five commonly prescribed PPIs and to delve into the clinical characteristics of the population experiencing psychiatric AEs, as well as the time-to-onset pattern of the reported AEs.

Methods: We performed disproportionality analysis to evaluate the PPI-related psychiatric AEs risk signal using data from the FDA adverse event reporting system.

Elemental Modulation Inducing Defect Engineering to Enhance Electrochemical Capacitance and Rectification Performance of High-Entropy Oxides.

Electrochemical capacitor diodes, integrating energy storage and ion rectification, hold great promise for practical applications. However, limitations in rectification ratio and specific capacitance hinder their widespread use. Here, high-entropy oxides were employed as electrode materials, with conductivity significantly enhanced via defect engineering and lattice optimization.

Post-coordination of Ru(ii) controlled regioselective B(4)-H acylmethylation of -carboranes with sulfoxonium ylides.

Despite significant progress in the B-H functionalization of carboranes, the development of cost-effective catalytic systems devoid of noble metals, coupled with mechanistic validation of regioselectivity control, remains a formidable challenge. Herein, we disclose an Ag salt-free, redox-neutral, and inexpensive ruthenium(ii)-catalyzed protocol that enables exclusive B(4)-H acylmethylation of -carboranes through a novel post-coordination strategy. By exploiting weakly coordinating carboxylic acid as a traceless directing group, this method achieves excellent mono-site selectivity for B-C(sp) bond formation using diverse sulfoxonium ylides, demonstrating both functional group tolerance and synthetic scalability.

Changes in early respiratory tract microecology associated with neonatal respiratory distress syndrome.

Objective: This study aimed to explore the distribution patterns of the early respiratory tract microbiome in infants with neonatal respiratory distress syndrome.

Methods: The study involved infants with neonatal respiratory distress syndrome who were admitted to the neonatal department of Kunming Children's Hospital between July and October 2022. Samples were obtained at two time points: 1 to 3 days post-admission (initial group) and 7 to 10 days post-admission (later group).

Essential angiosperm-specific subunits of HDA19 histone deacetylase complexes in Arabidopsis.

Although the Arabidopsis thaliana RPD3-type histone deacetylase HDA19 and its close homolog HDA6 participate in SIN3-type histone deacetylase complexes, they display distinct biological roles, with the reason for these differences being poorly understood. This study identifies three angiosperm-specific HDA19-interacting homologous proteins, termed HDIP1, HDIP2, and HDIP3 (HDIP1/2/3). These proteins interact with HDA19 and other conserved histone deacetylase complex components, leading to the formation of HDA19-containing SIN3-type complexes, while they are not involved in the formation of HDA6-containing complexes.

Asymmetric aza-Friedel-Crafts reaction of newly developed ketimines: access to chiral indeno[1,2-]quinoxaline architectures.

The functionalized 11-amino-indeno[1,2-]quinoxaline scaffold is a pivotal structural motif in diverse bioactive compounds. In this study, we developed a chiral phosphoric acid catalysed enantioselective aza-Friedel-Crafts reaction between indeno[1,2-]quinoxalin-11-imines and indoles. This methodology enables the synthesis of chiral hybrid architectures incorporating both 11-aminoindeno[1,2-]quinoxaline and indole moieties, achieving exceptional synthetic efficiency (up to 99% yield) with outstanding stereocontrol (up to 99% ee).

Structural characterization of a polysaccharide from Qi-Gui herb pair and its anti-tumor activity in colon cancer cells.

(Fisch.) Bunge and (Oliv.) Diels forms a classic herb pair (Qi-Gui her pair) in Chinese medicine, which was commonly used for treating menstrual anemia and microvascular ischemic diseases.

Crystal Transformation Strategy in Hydrogen-Bonded Organic Framework Solid-State Electrolyte for Stable Zinc-Ion Batteries.

Solid-state zinc ion batteries (ZIBs) hold great potential for sustainable and high-safety reserves. However, the advancement of solid-state ZIBs is constrained by the shortage of reasonable solid-state electrolytes (SSE) with abundant hopping sites, effective hydrogen evolution reaction (HER) inhibition, and favorable interfacial compatibility. Herein, the hydrogen-bonded organic framework (HOF) CAM-Ag with Zn hopping sites is developed as SSE for ZIBs.

Cinerols L-R, Anti-inflammatory Meroterpenoids from the Marine Sponge .

Seven new sesquiterpene hydroquinone/quinone (SQ) meroterpenoids, cinerols L-R (-), along with four known analogues (-), were identified from a marine sponge, , collected from the shore of the Xisha Islands in the South China Sea. The structures of - were established by the analysis of NMR, high-resolution MS, and comparison of the experimental and calculated electronic circular dichroism (ECD) spectra. Cinerol L () is particularly noteworthy, as it features a 5-pyrrolo[1,2a]-benzimidazole moiety modified by an ethyl sulfonate, while cinerols N () and O () possess a unique acetyl-substituted hydroquinone moiety.

Taurine and proline promote lung tumour growth by co-regulating Azgp1/mTOR signalling pathway.

Accurate metabolic biomarkers for lung cancer prognosis remain scarce but crucial. Taurine and proline, two metabolites, are consistently elevated across various cancer stages in previous studies, hinting at their potential role in disease progression. This study is the first to reveal how these metabolites contribute to poor prognosis.

Nicotinamide Mononucleotide and Nicotinamide Riboside Improve Dyslipidemia and Fatty Liver but Promote Atherosclerosis in Apolipoprotein E Knockout Mice.

Nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) are intermediary products in NAD+ metabolism. NMN and NR supplementation can elevate NAD+ levels in tissues, addressing health issues associated with aging and obesity. However, the impact of NMN and NR on atherosclerosis remains incompletely elucidated.

Crystal Structure and Physical Properties of a Layered Oxyarsenide SrVCrAsO.

We report the synthesis, crystal structure, and physical properties of the mixed transition-metal oxyarsenide SrVCrAsO. The compound has an ordered intergrowth structure with the perovskite-like layers of "SrVO" and the ThCrSi-type layers of "SrCrAs" stacking alternately along the crystallographic axis, in which ∼10% mixed occupancy between V and Cr is present for the sample synthesized by solid-state reactions. The electrical resistivity data show semiconducting-like behavior, probably associated with the occupancy disorders in the CrAs layers.

ThMoIrSiC: An Intergrown Superconductor by Structure Design.

Exploration of new superconductors in multicomponent complex systems remains challenging. Among complex superconductors, those containing distinct superconducting layers are quite rare. In this work, based on the block-layer model together with formation energy calculations, we have designed and successfully synthesized a quinary intermetallic compound, ThMoIrSiC.

Three-dimensional location approach with silk thread guided hepatectomy for liver tumor.

Background: Intraoperative determination of resection margin and adequate residual liver parenchyma are the key points of hepatectomy for the treatment of liver tumors. Intraoperative ultrasound and indocyanine green fluorescence navigation are the most commonly used methods at present, but the technical barriers limit their promotion.

Aim: To evaluate the value of the three-dimensional location approach with silk thread (3D-LAST) in precise resection of liver tumors.