Post-coordination of Ru(ii) controlled regioselective B(4)-H acylmethylation of -carboranes with sulfoxonium ylides.

Despite significant progress in the B-H functionalization of carboranes, the development of cost-effective catalytic systems devoid of noble metals, coupled with mechanistic validation of regioselectivity control, remains a formidable challenge. Herein, we disclose an Ag salt-free, redox-neutral, and inexpensive ruthenium(ii)-catalyzed protocol that enables exclusive B(4)-H acylmethylation of -carboranes through a novel post-coordination strategy. By exploiting weakly coordinating carboxylic acid as a traceless directing group, this method achieves excellent mono-site selectivity for B-C(sp) bond formation using diverse sulfoxonium ylides, demonstrating both functional group tolerance and synthetic scalability.

The impact of high humidex on the risk of hospital admissions for urinary system diseases in Lanzhou, China: A time-series analysis.

There is scant research on the association between humidex exposure and urinary system diseases. Hospitalization records from Lanzhou city were collected for the period 2015 to 2019, alongside daily meteorological and air pollution data for the study duration. Daily humidex was calculated using temperature and relative humidity indices.