Publications by authors named "Shan Cai"

Aqueous zinc-ion batteries (AZIBs) are promising candidates for large-scale energy storage; however, uncontrolled interfacial water remains a major hurdle, limiting both anode stability and ion transport. In this study, 2-picolinaldehyde (2PA) was chosen as a reversible hydration modulator (RHM) that enables dynamic regulation of interfacial free water. Spectroscopic and computational analyses revealed that RHM captures excess water during plating to suppress hydrogen evolution and corrosion while releasing water during stripping to facilitate Zn solvation and migration.

View Article and Find Full Text PDF

To examine the association between stages of exercise behavior change, as defined by the transtheoretical model (TTM), and obesity progression among Chinese children and adolescents, with attention to gender and urban-rural differences. A total of 5006 Chinese children and adolescents aged 9-18 years were assessed in 2019 and followed up in 2020. Participants were categorized into five TTM stages: precontemplation, contemplation, preparation, action, and maintenance.

View Article and Find Full Text PDF

Background: Over the past decades, Chinese school-aged children and adolescents have experienced a rapid increase in overweight and obesity, but corresponding changes in muscle strength remain unclear. We aimed to elucidate trends in muscle strength development at both national and subnational level, and to investigate whether it has increased proportionally with weight gain.

Methods: Muscle strength (handgrip strength [kg] for upper body and standing broad jump [cm] for lower body) and weight measurements for 1.

View Article and Find Full Text PDF

Drowning ranks as the third leading cause of unintentional injury deaths globally. We conducted a systematic analysis of drowning mortality and its associated risk factors. Data on mortality, years of life lost (YLLs), and risk factors related to drowning (ICD-10 codes W65-74) from 204 countries and territories between 1980 and 2021 were obtained from the Global Burden of Disease 2021.

View Article and Find Full Text PDF

Objective: To analyze the association between indoor light at night (LAN) exposure with myopia in children and adolescents.

Methods: A cross-sectional survey was conducted in 2023 involving 872 students aged 6-14 years in Beijing, China. Portable photometers continuously measured indoor LAN exposure over four nights.

View Article and Find Full Text PDF

Objective: We characterized the spatial-temporal trends of obesity among Chinese children and adolescents from 1985 to 2019 and examined the impact of social determinants of health (SDOH) patterns.

Methods: Using data from the Chinese National Survey on Students' Constitution and Health (CNSSCH) conducted between 1985 and 2019, featuring seven cross-sectional surveys, we employed spatial-temporal analysis methods and collected 23 obesity-related variables to identify SDOH patterns. A general linear regression model investigated associations between SDOH patterns and obesity prevalence.

View Article and Find Full Text PDF

Background: With increasing concerns about early-onset cardiovascular diseases, it is essential to understand the distribution of cardiovascular health among young adults. This study aimed to characterize trends in physical fitness and the prevalence of overweight/obesity (OWOB), elevated blood pressure (EBP), and their comorbidity among Chinese college students from 2000 to 2019 and to analyze the changes in their associations and subgroup differences.

Methods: Data were extracted from five cycles of the Chinese National Survey on Students' Constitution and Health (2000-2019), including 241,710 college students aged 19-22.

View Article and Find Full Text PDF

Background: Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous condition with different risk factors, including family history. This study aimed to explore association between a family history of chronic airway disease and features and outcomes of COPD.

Methods: Participants were obtained from the RealDTC study between December 2016 and December 2022.

View Article and Find Full Text PDF

Background: The influenza vaccination rate of chronic obstructive pulmonary disease (COPD) patients in China was very low. In this study, we aimed to evaluate the effect of clinician-led intensive health education on influenza vaccination in outpatients with COPD and the effect of influenza vaccination on the risk of acute exacerbations in the real world.

Methods: Participants were from the Real World Research of Diagnosis and Treatment of COPD study, a real-world prospective cohort study.

View Article and Find Full Text PDF

Objectives: Carbocysteine can reduce the frequency of acute exacerbations and improve respiratory symptoms to a certain extent in severe to very severe chronic obstructive pulmonary disease (COPD) patients. The objective of the study was to evaluate the efficacy of carbocysteine on the rate of exacerbations and pulmonary function for mild-to-moderate COPD patients.

Methods: In this phase 4, multicenter, double-blind, randomized, placebo-controlled, parallel-group trial, we randomly assigned mild-to-moderate COPD patients in a 2:1 ratio to treatment with carbocysteine (500mg, thrice daily) or matched placebo for 12 months.

View Article and Find Full Text PDF

Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 revised the combined chronic obstructive pulmonary disease (COPD) assessment, merging groups C and D into group E, and revised the initial inhalation therapy recommendation. We aimed to evaluate the treatment responses among different inhalation therapies in GOLD group E patients stratified by the COPD assessment test (CAT) scores and forced expiratory volume in one-second percentage of predicted (FEV1%pred).

Methods: In this retrospective cohort study, we included patients with COPD registered in the Real World Research of Diagnosis and Treatment of COPD (RealDTC) study between January 2017 and June 2023.

View Article and Find Full Text PDF

Background: We performed an umbrella review to synthesize evidence on the effects of physical activity (PA) interventions on indicators of physical and psychological health among children and adolescents, including body mass index (BMI), blood pressure (BP), depressive symptoms, and cognitive function.

Methods: PubMed, Embase, Web of Science, and the Cochrane Library were systematically searched from inception through 31 July 2023. We included meta-analyses of randomized controlled trials exploring the effects of PA interventions on BMI, BP, depressive symptoms, or cognitive function in healthy or general children and adolescents.

View Article and Find Full Text PDF

Recent increases in nitrogen dioxide (NO) and ozone (O), two highly reactive and oxidative pollutants, have raised concerns about their potential impact on adolescent mental health. This study leveraged data from the Chinese National Survey on Students' Constitution and Health (CNSSCH) in 2019, a nationally representative cross-sectional survey of Chinese adolescents. A total of 149,697 adolescents aged 10-18 years were included in this study.

View Article and Find Full Text PDF
Article Synopsis
  • Childhood hypertension is increasingly recognized as a significant health issue in China, necessitating accurate prevalence estimates for effective management.
  • The study conducted a systematic review and meta-analysis of literature from various databases, analyzing data from over 22 million children to estimate blood pressure-related health concerns.
  • In 2020, the study found that 3.11% of Chinese children aged 6-18 were hypertensive, which translates to approximately 6.8 million affected children nationwide.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to analyze the distribution of hemorrhoids among adults undergoing physical exams in China, providing insights for better prevention and intervention strategies.
  • A total of nearly 2.94 million adults were examined, revealing a significantly higher detection rate of hemorrhoids in women (43.7%) compared to men (17.7%), with specific age groups showing varying prevalence.
  • Factors such as age, obesity, and hypertension were identified as influences on the likelihood of having hemorrhoids, suggesting the need for targeted awareness and screening initiatives.
View Article and Find Full Text PDF
Article Synopsis
  • The study explored how past exacerbation history affects future exacerbations and mortality in COPD patients categorized by the GOLD A and B classifications.
  • Data was collected from 8318 COPD patients in China between 2017 and 2022, tracking their health outcomes until December 2023 or death, focusing on exacerbation events and mortality rates.
  • Results showed that patients in the GOLD E group had the highest risk of future exacerbations and mortality, while those in GOLD A1 experienced significantly increased risks compared to GOLD A0; specific inhaled corticosteroids were found to be beneficial in reducing exacerbation risks in certain groups.
View Article and Find Full Text PDF

Evidence for the treatment of patients with mild-to-moderate chronic obstructive pulmonary disease (COPD) is limited. The efficacy of N-acetylcysteine (an antioxidant and mucolytic agent) for patients with mild-to-moderate COPD is uncertain. In this multicentre, randomised, double-blind, placebo-controlled trial, we randomly assigned 968 patients with mild-to-moderate COPD to treatment with N-acetylcysteine (600 mg, twice daily) or matched placebo for two years.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to determine the safety and effectiveness of early comprehensive pulmonary rehabilitation for patients hospitalized with acute exacerbations of chronic obstructive pulmonary disease (COPD).
  • Involving 108 patients, the research measured outcomes like walking distance, quality of life, breathlessness, and muscle strength, finding significant improvements in walking distance and inspiratory muscle strength for those receiving rehabilitation compared to usual care.
  • The results suggest that early pulmonary rehabilitation is both safe and beneficial, offering noticeable improvements in patient outcomes and being recommended to start during the early stages of hospitalization.
View Article and Find Full Text PDF
Article Synopsis
  • The study addresses the growing issue of metabolic-associated steatotic liver disease (MASLD) in children, particularly those in obesity-heavy regions, highlighting the challenge of identifying at-risk individuals due to a lack of clear symptoms.
  • Researchers conducted a school-based survey in Beijing to create predictive models for MASLD and validated these models in Ningbo, comparing various statistical methods to determine the most effective approach for screening.
  • The logistic regression model identified the waist-to-height ratio (WHtR) as the best non-invasive predictor for MASLD, and the combination of WHtR with lipid accumulation product (LAP) enhanced prediction accuracy.
View Article and Find Full Text PDF

What Is Already Known About This Topic?: High levels of mental well-being are linked to favorable life outcomes. Nonetheless, compared to the research on psychiatric disorders, the understanding of mental well-being among Chinese adolescents is still relatively underexplored.

What Is Added By This Report?: This report fills a significant void in the literature concerning the mental well-being of Chinese adolescents by providing updated data.

View Article and Find Full Text PDF

Objective: To describe the current distribution of daily physical activity time among elementary and junior high school students in Beijing, and to analyze the influencing factors and pathways at the individual, family, school and community levels.

Methods: Data were drawn upon from a cross-sectional investigation in Beijing in 2023, and a total of 3 157 elementary and junior high school students were included in the final analysis. Questionnaire was used to collect data on basic characteristics, overall and in-school physical activity time per day, the number of sports mastered, perceived physical activity benefits and barriers scales, perceived family, school, and community physical activity supportive environment scales.

View Article and Find Full Text PDF

Background: To explore trends of the association between body mass index (BMI) and age at menarche or spermarche and its urban-rural disparities from 1995 to 2019.

Methods: A total of 912 753 children and adolescents - including 519 940 9-18 years old girls and 392 813 11-18 years old boys - were involved in six successive cross-sectional surveys conducted across 30 provinces in China from 1995 to 2019. Data on menarche and spermarche was collected using the status quo method, where same-gender physicians conducted face-to-face interviews to determine if children and adolescents had experienced their first menstrual cycle or ejaculation (yes/no).

View Article and Find Full Text PDF

Background: The urban-rural disparities in overweight and obesity among children and adolescents are narrowing, and there is a need for long-term and updated data to explain this inequality, understand the underlying mechanisms, and identify priority groups for interventions.

Methods: We analyzed data from seven rounds of the Chinese National Survey on Students Constitution and Health (CNSSCH) conducted from 1985 to 2019, focusing on school-age children and adolescents aged 7-18 years. Joinpoint regression was used to identify inflection points (indicating a change in the trend) in the prevalence of overweight and obesity during the study period, stratified by urban/rural areas and sex.

View Article and Find Full Text PDF

What Is Already Known About This Topic?: Myopia has been identified as a significant emerging challenge and policy priority among children and adolescents in China by the Ministry of Education and seven other departments. Limited research has been conducted to investigate the collective impact of outdoor time and other modifiable factors on the incidence of myopia.

What Is Added By This Report?: This study provides support for the protective effect of combining increased outdoor time with other prevention strategies in reducing the incidence of myopia.

View Article and Find Full Text PDF

Background: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. There is no nomogram model available for mortality prediction of stable COPD. We intended to develop and validate a nomogram model to predict mortality risk in stable COPD patients for personalised prognostic assessment.

View Article and Find Full Text PDF