Quantification of Fatty Acids from Arctium lappa L. Leaves by C qNMR and HPLC-CAD.

Arctium lappa L. (burdock) leaves is effective in the traditional treatment of stroke. Fatty acids are abundant in burdock leaves, and may play an important role in the treatment of stroke.

Application of the Composite Electrical Insulation Layer with a Self-Healing Function Similar to Pine Trees in K-Type Coaxial Thermocouples.

Aerospace engines and hypersonic vehicles, among other high-temperature components, often operate in environments characterized by temperatures exceeding 1000 °C and high-speed airflow impacts, resulting in severe thermal erosion conditions. Coaxial thermocouples (CTs), with their unique self-eroding characteristic, are particularly well suited for use in such extreme environments. However, fabricating high-temperature electrical insulation layers for coaxial thermocouples remains challenging.

Association Between Exercise Behavior Stages and Obesity Transition in Children and Adolescents: A Nationwide Follow-Up Study.

To examine the association between stages of exercise behavior change, as defined by the transtheoretical model (TTM), and obesity progression among Chinese children and adolescents, with attention to gender and urban-rural differences. A total of 5006 Chinese children and adolescents aged 9-18 years were assessed in 2019 and followed up in 2020. Participants were categorized into five TTM stages: precontemplation, contemplation, preparation, action, and maintenance.

Case Report: Two children with factor XII deficiency caused by novel compound heterozygous variants.

Background: Factor XII (FXII) deficiency (OMIM 234000) is a rare hereditary coagulation disorder caused by pathogenic variants within the gene. It causes prolonged activated partial thromboplastin time without bleeding diathesis. Most patients have no obvious clinical symptoms, so the disease is difficult to be detected.

Curcumin-loaded polyvinyl alcohol/nanocellulose/ nano zinc oxide nanofiber membranes with enhanced strength, moisture resistance, and antibacterial properties.

To meet the practical application demands of nanofiber membranes (NFMs) under humid conditions, a PVA/NC/ZnO NFM was successfully fabricated by incorporating nano zinc oxide (ZnO) into a polyvinyl alcohol (PVA)/nanocellulose (NC) matrix, combined with nitrogen-assisted thermal treatment. The synergistic effect of ZnO-induced heterogeneous nucleation and thermal processing significantly enhanced the crystallinity of the NFM (up to 49.71 %), improving its anti-swelling behavior and liquid absorption capacity-with an absorption rate of up to 1906 % for artificial blood.

An Efficient Fog Collection Origami Janus Membrane for Rapid Directional Water Transport and Omnidirectional Fog Harvesting.

Existing Janus fog harvesting technologies struggle to achieve efficient and continuous fog collection across various fog flow directions. In this work, we developed a Janus fog harvesting (JHL) system, characterized by a boundary-free Janus system formed by selective modification with octadecanethiol, creating a pair of hydrophilic and hydrophobic domains. The system features a 3D origami macrostructure composed of scallop arrays and shaped like an improved trumpet flower.

Application of Bioinspired Structural Ceramics with High-Temperature Electrical Insulation and High Adhesion in K-Type Coaxial Thermocouples.

Surface erosion of the coaxial thermocouple probe initiates continuous bridging of thermoelectric materials on the insulation layer surface, forming new temperature measurement junctions. This inherent ability to measure continuous self-erosion ensures the operational reliability of the coaxial thermocouples in high-temperature ablative environments. However, the fabrication of a high-temperature electrical insulation layer and a high-adhesion insulating layer in the coaxial thermocouples remains a challenge.

Implicit neural representation for medical image reconstruction.

Medical image reconstruction aims to generate high-quality images from incompletely sampled raw sensor data, which poses an ill-posed inverse problem. Traditional iterative reconstruction methods rely on prior information to empirically construct regularization terms, a process that is not trivial. While deep learning-based supervised reconstruction has made significant progress in improving image quality, it requires large-scale training data, which is difficult to obtain in medical imaging.

Dual associations of post-sleep and pre-wake light-at-night (LAN) exposure with myopia in children and adolescents.

Objective: To analyze the association between indoor light at night (LAN) exposure with myopia in children and adolescents.

Methods: A cross-sectional survey was conducted in 2023 involving 872 students aged 6-14 years in Beijing, China. Portable photometers continuously measured indoor LAN exposure over four nights.

Spatial-temporal analysis and spatial drivers of childhood obesity in China from 1985 to 2019.

Objective: We characterized the spatial-temporal trends of obesity among Chinese children and adolescents from 1985 to 2019 and examined the impact of social determinants of health (SDOH) patterns.

Methods: Using data from the Chinese National Survey on Students' Constitution and Health (CNSSCH) conducted between 1985 and 2019, featuring seven cross-sectional surveys, we employed spatial-temporal analysis methods and collected 23 obesity-related variables to identify SDOH patterns. A general linear regression model investigated associations between SDOH patterns and obesity prevalence.

Myocardialmapping at 5T using multi-inversion recovery real-time spoiled GRE.

To develop an accurate myocardialmapping technique at 5T using Look-Locker-based multiple inversion-recovery with the real-time spoiled gradient echo (GRE) acquisition.The proposedmapping technique (mIR-rt) samples the recovery of inverted magnetization using the real-time GRE and the images captured during diastole are selected forfitting. Multiple-inversion recoveries are employed to increase the sample size for accurate fitting.

[Saltwater stir-fried Plantaginis Semen alleviates renal fibrosis by regulating epithelial-mesenchymal transition in renal tubular cells].

This study aimed to investigate the effect of saltwater stir-fried Plantaginis Semen(SPS) on renal fibrosis in rats and decipher the underlying mechanism. Thirty-six Sprague-Dawley rats were randomly assigned into control, model, losartan potassium, and low-, medium-, and high-dose(15, 30, and 60 g·kg~(-1), respectively) SPS groups. Rats in other groups except the control group were subjected to unilateral ureteral obstruction(UUO) to induce renal fibrosis, and the modeling and gavage lasted for 14 days.

Secular trends in physical fitness and cardiovascular risks among Chinese college students: an analysis of five successive national surveys between 2000 and 2019.

Background: With increasing concerns about early-onset cardiovascular diseases, it is essential to understand the distribution of cardiovascular health among young adults. This study aimed to characterize trends in physical fitness and the prevalence of overweight/obesity (OWOB), elevated blood pressure (EBP), and their comorbidity among Chinese college students from 2000 to 2019 and to analyze the changes in their associations and subgroup differences.

Methods: Data were extracted from five cycles of the Chinese National Survey on Students' Constitution and Health (2000-2019), including 241,710 college students aged 19-22.

Study on the potential links between clinical features of oral lichenoid mucositis and systemic diseases.

Objective: This study aimed to analyze the clinical characteristics of oral lichenoid disease and investigate its potential association with systemic diseases.

Methods: This study was a retrospective cross-sectional analysis. The study comprised 116 patients who had been diagnosed with oral lichenoid disease, including 70 with oral lichen planus and 46 with lichenoid lesions.

Exploring the Efficacy and Mechanism of Astragalus Polysaccharide in Treating Allergic Asthma through Network Pharmacology, Bioinformatics, and Experimental Verification.

Background: Allergic asthma is an inflammatory disease of the airways that causes great distress to the patient's normal life. Astragalus Polysaccharide (APS) is the main active ingredient in the traditional Chinese medicine Astragalus mongholicus Bunge, which has the effect of regulating immune function.

Objective: This study aimed to evaluate the effect of APS on allergic asthma and investigate its potential mechanism of action.

An upfront patient selection strategy based on personalized data-driven computed tomography generation for deep inspiration breath-hold in breast radiotherapy.

Background: Currently there is no widely used upfront selection method to determine whether patients are suitable for deep inspiration breath-hold (DIBH) in left-sided breast radiotherapy.

Purpose: To establish an upfront patient selection strategy to improve the decision-making efficiency of DIBH and avoid extra computed tomography (CT) exposure to patients.

Methods: A total of 174 patients who underwent both free-breathing (FB) and DIBH scans were enrolled.

Efficient direction-independent 3D spiral fog collector.

Inspired by the natural structures of cacti and desert beetles, a novel three-dimensional (3D) high-efficiency fog collector is proposed. This design integrates a unique macro-structural configuration with a surface wettability gradient that remains independent of the fog flow direction. The fog collector adopts an integral spiral structure, with superhydrophilic triangular protrusions uniformly distributed across its surface.

Monocytes Expressing IL-36G Play a Crucial Role in Atopic Dermatitis.

Atopic dermatitis (ad) is a chronic inflammatory skin disease, with recent studies indicating that immune cells, such as monocytes and inflammatory cytokines, play a crucial role. By retrieving datasets from public databases and analysing immune cell infiltration in lesional skin using CIBERSORT, we found that monocytes and M2 macrophages were significantly upregulated in atopic dermatitis. Differentially expressed gene (DEG) functional enrichment analysis revealed that cytokine-cytokine receptor interaction was the most significantly enriched pathway.

Increased risks of type II diabetes among older Asian, Native Hawaiian, and Pacific Islander lung cancer survivors: a SEER-Medicare analysis.

Purpose: Asian, Native Hawaiian, and Pacific Islanders (ANHPI) have a higher prevalence of type II diabetes compared to the non-Hispanic White (NHW) population. However, the incidence of type II diabetes among ANHPI lung cancer survivors is unknown. The aim of this study is to investigate the risk of newly diagnosed type II diabetes among older ANHPI lung cancer survivors compared to older NHW lung cancer survivors.

Revealing the Principle of Progressively Enhanced Photocatalytic Reactivity in Dual Single-Atoms-Mediated Electronic Interactions Optimization of Cd/Te-TiO.

In this work, a CdTe@TiO single atoms (SAs) catalysts is successfully synthesized, realizing unique portion of nonbonding oxygen-coordinated configuration of Cd─O─Te dimers coupling. Astonishingly, the 5th CdTe@TiO (0.027 min) shows progressively augmenting phenomenon, accompanied with 2.

Bioinformatics and Network Pharmacology Identify the Therapeutic Role of Guominkang in Allergic Asthma by Inhibiting PI3K/Akt Signaling.

Background: As a classical regulating formula, Guominkang (GMK) has been extensively employed in clinical practice to treat the allergic asthma (AA) and alleviate allergy symptoms, however, the underlying mechanism remains elusive. The aim of this study was to explored the mechanism of action through which GMK combats AA.

Methods: Potential target genes for the compounds were identified from the database and subjected to functional enrichment analysis.

DHX36-mediated G-quadruplexes unwinding is essential for oocyte and early embryo development in mice.

DHX36 plays a crucial role in regulating transcriptional and post-transcriptional processes through its interaction with G-quadruplexes (G4s). The mechanisms by which DHX36 regulates G4s vary across different cell types and physiological conditions. Oocyte-specific conditional knockout (CKO) mice were utilized to study the impact of DHX36 deficiency on female fertility.

Polylactic acid aerogel with antibacterial, early warning and heat preservation functions applied to fresh trays.

Fresh trays could not provide efficient protection and detection to the fresh foods during the transportation and sale processes due to its less functions. To address these challenges, one type of multifunctional fresh tray with antibacterial and detection properties was fabricated by the combining of two types of functionalized polylactic acid (PLA) aerogels, PLA/carvacrol (PLA/CA) aerogel and PLA-red cabbage anthocyanin (PLA-RCA) aerogel. The PLA/CA aerogel prepared by in situ encapsulation strategy exhibits a strong antioxidant effect with the free radical clearance rate of 69.

Deep attention model for arrhythmia signal classification based on multi-objective crayfish optimization algorithmic variational mode decomposition.

The detection and classification of arrhythmia play a vital role in the diagnosis and management of cardiac disorders. Many deep learning techniques are utilized for arrhythmia classification in current research but only based on ECG data, lacking the mathematical foundations of cardiac electrophysiology. A finite element model (FEM) of the human heart based on the FitzHugh-Nagumo (FHN) model was established for cardiac electrophysiology simulation and the ECG signals were acquired from the FEM results of representative points.

Quantitative nuclear magnetic analysis of human milk oligosaccharides 2'-fucosyllactose and 3-fucosyllactose in complicated food matrices.

Human milk oligosaccharides (HMOs) are the third most abundant solid component in breast milk, which is essential for the healthy growth of infants. 2'-fucosyllactose (2'-FL) and 3-fucosyllactose (3-FL) are the main components of HMOs. In this study, we developed and validated a quantitative nuclear magnetic resonance (qNMR) method for determining HMOs in different complex food matrices.