Regulatory mechanisms of total phosphorus on NO concentrations: A case study of Dongting lake.

Lakes serve as critical regulators of biogeochemical processes, acting as hotspots for nitrous oxide (NO) emissions while simultaneously retaining substantial phosphorus loads. However, the role of total phosphorus (TP) in shaping NO dynamics remains poorly understood. Here, we investigated TP-mediated changes in NO concentrations in Dongting Lake, China, using a classification framework based on national water quality standards, validated with the GRiMe dataset and machine learning approaches.

Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patients.

Background: Glioblastoma (GBM) is a highly aggressive brain tumor with poor prognosis and limited response to immunotherapy. Immune escape-related genes (IERGs) are increasingly recognized as critical regulators of tumor progression and immune evasion. However, their prognostic value in GBM remains unclear.

Multi-omics reveals the genetic regulation and functions of long non-coding RNAs in tomato.

Long non-coding RNAs (lncRNAs) play vital roles in signal transduction and plant development. However, how lncRNA expression might have been globally altered during Solanum lycopersicum (tomato) breeding and what potential roles they play in regulating metabolite accumulation in fruit remain unclear. Here, we identified 15,548 lncRNAs using RNA-sequencing data from 404 tomato accessions.

Versatile Design of Metal Aerogels for Environmental Remediation: An Overview.

As one of the latest members in the aerogel family, metal aerogels (MAs) appear to be promising materials entirely structured from nanosized metals. The combined attributes of nanometals and aerogels render them a special class of porous materials with vast potential in diverse fields. Growing environmental concerns have spurred interest in MAs for environmental remediation.

Controlled synthesis of noble metal aerogels mediated by salts.

Noble metal aerogels (NMAs) are typically assembled from metal nanoparticles, thus combining the physicochemical properties of nanostructured metals with the self-standing porous architecture of aerogels. NMAs therefore have potential in catalysis, sensing and other applications where the controlled manipulation of their structure and composition facilitates their use in fundamental and applied sciences. However, their preparation remains challenging due to the particular gelation behavior displayed by metal systems.

Hybrid Active Sites in Coordination Polymers Enable Ampere-Level Acetylene Semihydrogenation in Membrane Electrode Assembly Systems.

Electrocatalytic acetylene semihydrogenation in membrane electrode assembly systems promises a sustainable pathway for ethylene production, yet faces challenges in catalyst performance and durability. Herein, we developed a Cu coordination polymer with hybrid sites that synergistically integrate open Cu sites and N-heterocyclic carbenes. These hybrid sites bestow the coordination polymer with acetylene gasophilicity, hydrophobicity toward water, and readily accessible active Cu sites, which energetically facilitate acetylene absorption and vinyl intermediate formation, thereby enabling efficient ethylene production at ampere-level current densities.

Freezing-Mediated Synthesis and Applications of Porous Metals.

Porous metals combine the physicochemical properties of metals and structural features of porous materials, which are characterized as a special class of materials promising in various fields such as tissue engineering, energy storage and conversion, electronics, and sensing. Among diverse fabrication approaches, freezing-mediated synthesis (e.g.

Scorpion venom peptides enhance immunity and survival in through antibacterial action against .

Introduction: Scorpion venom-derived antimicrobial peptides (AMPs) have emerged as promising candidates for combating bacterial infections owing to their potent activity and unique mechanisms of action. This study focuses on three 13-amino-acid peptides-BmKn1, BmKn2, and BmKn2-7-derived from the venom of . The aim is to elucidate their structural features, antibacterial efficacy, and immunomodulatory effects in infected with (VP).

Multi-Omics Analyses Reveal the Red and Far-Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana.

Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of transient expression remains unexplored. In this study, we examined the influence of five representative light qualities with varying wavelength mix on the N.

Phyllosphere mycobiome in two Lycopodiaceae plant species: unraveling potential HupA-producing fungi and fungal interactions.

Huperzine A (HupA), a lycopodium alkaloid with therapeutic potential for neurodegenerative diseases such as Alzheimer's disease, is found exclusively in some species of the Huperzioideae subfamily of Lycopodiaceae. Fungi associated with Huperzioideae species are potential contributors to HupA biosynthesis, offering promising prospects for HupA production. Despite its medical significance, limited knowledge of fungal diversity in lycophytes and the variability of HupA production in fungal strains have impeded the discovery and applications of HupA-producing fungi.

Glutathione triggers leaf-to-leaf, calcium-based plant defense signaling.

Animals rely on nervous systems to cope with environmental variability, whereas plants are characterized by lack of nervous system but still have evolved systemic communication systems through signaling molecules that trigger long-distance defense signaling events when encountered with environmental challenges. Here, our genetic screening of the previously constructed hairpin RNA-based Arabidopsis library identifies a glutathione (GSH)-deficient mutant that has high accumulation of glutamate (Glu), a previously defined wound signal essential for activating plant defense, but disharmoniously exhibits attenuation of defense signaling events. We further uncover GSH as a critical signaling molecule that relies on GLUTAMATE RECEPTOR-LIKE 3.

Zn(II)/La(III) Coordination Polymers Based on New Schiff Base Ligands for Highly Selective and Sensitive Detection of 2,4,6-Trinitrophenol.

In recent years, nitro explosives have posed a threat to national security and human health due to their hazard and environmental contamination. The rapid and effective detection of nitro explosives remains a challenge. In this work, a new Schiff base ligand HL was carefully designed and successfully synthesized, HL = 1,1'-((1,1')-(cyclohexane-1,4-diylbis (azanylidene)) bis (methylidene) bis (naphthalene-2-ol).

Measurement of population agglomeration, dynamic change characteristics, and motivations in metropolitan agglomerations-A case study of the Xi'an metropolitan area.

This article compares the population agglomeration characteristics of the Xi'an metropolitan area in western China with those of metropolitan areas in other regions officially approved by the Chinese government. The kernel density estimation method and Markov chain model were used to conduct the study. The results revealed that from 2010 to 2020, the population agglomeration level of the Xi'an metropolitan area showed a trend of first increasing and then decreasing.

A genomic variation map provides insights into potato evolution and key agronomic traits.

Hybrid potato breeding based on diploid inbred lines is transforming the way of genetic improvement of this staple food crop, which requires a deep understanding of potato domestication and differentiation. In the present study, we resequenced 314 diploid wild and landrace accessions to generate a variome map of 47,203,407 variants. Using the variome map, we discovered the reshaping of tuber transcriptome during potato domestication, characterized genome-wide differentiation between landrace groups Stenotomum and Phureja.

Sowing Clean-Release Salt Catalyst for the Synthesis of Contamination-Free Single-walled Carbon Nanotube Arrays.

Horizontal arrays of single-walled carbon nanotubes (SWCNTs) have shown immense potential for application in emerging devices due to their excellent electrical and thermal properties. The direct growth of SWCNT arrays using high-activity metal catalysts is one of the promising methods to approach the mass production of dense SWCNT arrays. However, an inevitable obstacle lies in the post-purification of metal residual.

Releasing a sugar brake generates sweeter tomato without yield penalty.

In tomato, sugar content is highly correlated with consumer preferences, with most consumers preferring sweeter fruit. However, the sugar content of commercial varieties is generally low, as it is inversely correlated with fruit size, and growers prioritize yield over flavour quality. Here we identified two genes, tomato (Solanum lycopersicum) calcium-dependent protein kinase 27 (SlCDPK27; also known as SlCPK27) and its paralogue SlCDPK26, that control fruit sugar content.

Mercaptoimidazole-capped gold nanoparticles as a potent agent against plant pathogenic fungi.

Plant pathogenic fungi pose a substantial challenge to agricultural production, but the conventional fungicide-based approaches are losing importance. As agents with broad-spectrum antibacterial effects, gold nanoparticles (Au NPs) are found to have antifungal effects; however, no study has examined their application in agriculture as fungicides. Accordingly, this study investigates the activity of 2-mercaptoimidazole-capped Au NPs (MI-Au NPs) against the 'top' plant pathogenic fungi, finding that they could inhibit , , and by inducing cytoplasmic leakage.

Climate Disaster and Cognitive Ability: Evidence From Wildfire.

Objectives: We investigate the impact of wildfire disasters on cognitive health (i.e., thinking and language skills) in individuals aged 10 years and older using 2014 and 2018 wildfire and cognitive ability survey data from China.

Mismatch Negativity and P300 in the Diagnosis and Prognostic Assessment of Coma and Other Disorders of Consciousness.

Background: The objective of this study was to investigate the value of mismatch negativity (MMN) and P300 event-related potentials for discriminating the consciousness state and predicting improvement of consciousness at 6 months in patients with coma and other disorders of consciousness (DOC).

Methods: We performed MMN and P300 on 42 patients with DOC with a mean onset time of 40.21 ± 19.

Single-cell transcriptomic profiling reveals decreased ER protein Reticulon3 drives the progression of renal fibrosis.

Chronic kidney disease (CKD) poses a significant global health dilemma, emerging from complex causes. Although our prior research has indicated that a deficiency in Reticulon-3 (RTN3) accelerates renal disease progression, a thorough examination of RTN3 on kidney function and pathology remains underexplored. To address this critical need, we generated Rtn3-null mice to study the consequences of RTN3 protein deficiency on CKD.

Urban amenity and urban economic resilience: evidence from China.

Under the influence of multiple uncertain factors at home and abroad, urban amenities, as the underlying support for urban renewal activities, are of great significance in enhancing urban economic resilience. The panel data of Chinese cities from 2011 to 2019 is used in this study. Urban amenity is measured from artificial amenities and climate amenities, respectively.

Lab on the Microneedles: A Wearable Metal-organic Frameworks-Based Sensor for Visual Monitoring of Stress Hormone.

Abnormal secretion and dysrhythmias of cortisol (CORT) are associated with various diseases such as sleep disorders, depression, and chronic fatigue. Wearable devices are a cutting-edge technology for point-of-care detection and dynamic monitoring of CORT with inspiring convenience. Herein, we developed a minimally invasive skin-worn device with the advanced integration of both interstitial fluid (ISF) sampling and target molecule sensing for simultaneous detection of CORT via a microneedle-based sensor with high sensitivity, excellent efficiency, and outstanding reproducibility.

A new missense mutation c.1240A>G in fumarate hydratase gene leads to uterine leiomyoma associated hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome in Chinese.

Objective: This study presents a detailed analysis of the clinical and genetic characteristics of uterine leiomyoma associated with Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC), combined with exploration of family history, pathology, and management procedures, supported by thorough evidence collection.

Methods: Blood samples were collected from the proband, and the pathogenic variant was verified using Sanger sequencing. A comprehensive review of family history, FH deficiency pathology, FH and 2SC immunohistochemistry staining was conducted.