J Hazard Mater
September 2025
Hexanitrohexaazaisowurtzitane (CL-20) is a powerful explosive with significant environmental and ecotoxicological concerns. Industrial production of CL-20 generates acidic effluents containing residual CL-20, posing treatment challenges and resource loss. This study investigated four macroporous resins (DA201-C, NKA-2, D730, and D121) for CL-20 removal and recovery.
View Article and Find Full Text PDFDiabetic kidney disease (DKD) is a common chronic microvascular complication of diabetes and the leading cause of end-stage renal disease. Its pathogenesis is closely linked to cellular senescence. Studies have shown that cellular senescence drives DKD progression multiple mechanisms, including tubulointerstitial fibrosis, glomerulosclerosis, oxidative stress, and aberrant AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) signaling.
View Article and Find Full Text PDFIndustrial wastewater pollution has emerged as a significant global environmental challenge, particularly regarding the urgent need to address highly acidic industrial effluents containing organic pollutants. As a novel high-energy explosive, hexanitrohexaazaisowurtzitane (CL-20) inevitably generates strongly acidic wastewater during its production and application processes, posing severe threats to ecological systems and human health. This study systematically investigates the adsorption performance of two silicon-based materials, sodium silicate (NaSiO) and silicic acid (HSiO), for the removal of CL-20 from wastewater.
View Article and Find Full Text PDFAims: Papillary thyroid cancer (PTC) is a serious threat to human health worldwide, while metastasis in the early phase limits therapeutic success and leads to poor survival outcomes. The CXC chemokine receptor type 4 (CXCR4) plays an important role in many cellular movements such as transcriptional modulation, cell skeleton rearrangement, and cell migration, and the change in CXCR4 levels are crucial in various diseases including cancer. In this study, we explored the role of CXCR4 in the migration and invasion of PTC and investigated the potential mechanisms underlying its effects.
View Article and Find Full Text PDFMethylene blue (MB) is a refractory organic pollutant that poses a potential threat to the aquatic environment. Fenton reaction is considered a primrose strategy to treat MB. However, the traditional Fenton process is plagued by narrow pH application range, poor stability, and secondary pollution.
View Article and Find Full Text PDFInt J Biol Macromol
October 2024
To preserve the activity of amine groups on chitosan, chitosan resin (CR) was synthesized using the reversed-phase suspension two-step crosslinking method for the adsorption of palladium from wastewater. The effects of varying the amounts of chitosan, liquid paraffin, ethyl acetate, formaldehyde solution, and epichlorohydrin on the adsorption capacity of CR were investigated using both single-factor experiments and response surface methodology. The preparation conditions for the chitosan resin were optimized, and its adsorption properties were systematically evaluated.
View Article and Find Full Text PDFSkin Res Technol
August 2024
Front Microbiol
May 2024
Background: Microorganisms in biofilms are particularly difficult to control because of their increased survival and antibiotic resistance. Allicin and domiphen were employed to inhibit the microbial growth and biofilm formation of , , and strains.
Methods: Broth microdilution method and checkerboard assay were conducted to determine the efficacy of allicin combined with domiphen against , , and .
Chloromethyl styrene resin can undergo specific chemical modifications and is an excellent adsorbent material for treating difficult-to-degrade substances in wastewater. In this study, chloromethyl styrene resin will be used as a carrier, and polystyrene chloromethyl resin (PS-Cl) was converted into PS-NH by amino modification. The self-assembly of cobalt-based metal-organic framework (CoMOF) was induced on the surface of PS-NH by using a novel preparation technique.
View Article and Find Full Text PDFExp Ther Med
March 2024
Piperacillin-tazobactam is a clinically used antibiotic consisting of the semisynthetic penicillin piperacillin and the β-lactamase inhibitor tazobactam. Piperacillin-tazobactam is a broad-spectrum antibiotic used clinically to treat infections caused by gram-positive and gram-negative aerobic and anaerobic bacteria. The most common adverse reactions are gastrointestinal symptoms and skin reactions.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
December 2023
2,4,6-Trinitrotoluene (TNT) production processes generate a substantial amount of toxic wastewater. Therefore, it is crucial to identify efficient and sustainable methods for treating this wastewater. This paper explores the application of sustainable biomass-derived carbon produced from rice straw for the adsorption of 2,4,6-trinitrotoluene (TNT) red water.
View Article and Find Full Text PDFDenitrifying system is a feasible way to remove nitro-aromatic compounds (NACs) in wastewater. However, the toxicity and mechanisms of NACs to denitrification remain unknown. This study investigated effects of nitrobenzene (NB, a typical NAC) on denitrification in short term.
View Article and Find Full Text PDFThe safety of sodium-glucose co-transporter 2 (SGLT2) inhibitors in elderly patients with diabetic kidney disease (DKD) is still controversial. This study aimed to analyze the safety of SGLT2 inhibitors in elderly patients with type 2 diabetes mellitus (T2DM) and DKD. We systematically searched PubMed, Embase, Web of Science, and the Cochrane Library from inception to March 2023.
View Article and Find Full Text PDFBackground: Diabetic cardiomyopathy, secondary to diabetes, is the main cause of death in patients with diabetes. In China, traditional Chinese medicine has achieved good performance in treating diabetic cardiomyopathy. However, to date, no systematic review or meta-analysis has been published on the treatment of diabetic cardiomyopathy by traditional Chinese medicine.
View Article and Find Full Text PDFBiomed Res Int
October 2022
Background: Salt-sensitivity hypertensives (SSH) are an independent risk factor for cardiovascular disease. However, the mechanism of SSH is not clear. This study is aimed at constructing a competing endogenous RNA (ceRNA) network related to SSH.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
February 2023
Activated sludge process was a low-cost alternative method compared to the conventional physicochemical process for the treatment of heavy metal-containing wastewater. In the present study, the removal efficiency of Pb, Cu, and Ni from wastewater by a sequencing batch reactor (SBR) activated sludge system was investigated, and the mechanism was revealed by static adsorption experiment of activated sludge. The results showed that the activated sludge in the SBR system was effective in removing Pb and Cu from wastewater at 10 mg·L initial concentration, with a removal efficiency of 83.
View Article and Find Full Text PDFChemosphere
November 2022
Revealing the activation mechanism of nitrate (NO) reduction is crucially important to design high-efficiency photocatalysts for NO removal. In this work, the performance of photoreduction NO has been thoroughly studied over different crystalline phases TiO. Photodegradation rate of NO over anatase TiO is found to be higher than that of rutile TiO at simulated sunlight, which can achieve high NO conversion of 94% and 100% nitrogen selectivity (original concentration of 50 mg/L NO-N) at reaction time of 4 h.
View Article and Find Full Text PDFMedicine (Baltimore)
April 2022
Background: Dipeptidyl-peptidase IV inhibitor (DPP-4i) is a common hypoglycemic medication in treating type 2 diabetes millitus. It has become widely utilized in clinical practice due to its ability to effectively manage blood glucose while posing a low risk of hypoglycemia and weight gain. However, there is no consensus on DPP-4i's pancreatic safety due to a paucity of clinical evidence.
View Article and Find Full Text PDFSci Total Environ
February 2022
A large amount of heavy metal-contained wastewater (HMW) was discharged during Chinese industry development, which has caused many environmental problems. This study reviewed discharge, management and treatment of HMW in China through collecting and analyzing data from China's official statistical yearbook, standards, technical specifications, government reports, case reports, and research paper. Results showed that industry wastewater discharged by an amount of about 221.
View Article and Find Full Text PDFBioresour Technol
March 2022
The development of dairy industry is accompanied by large volumes of wastewater production, which is threaten to human's health and the biosphere. In this study, synthetic dairy wastewater was treated by immobilized microbial technology using polyurethane foam as carrier. Batch experiments were conducted to determine the effects of different operational parameters, and an up-flow immobilized microbial reactor was built to investigate long-term performance of the system.
View Article and Find Full Text PDFTo explore the mechanism of the Astragalus membranaceous (AM)-Angelica sinensis (AS) compound in the treatment of diabetic nephropathy (DN) we used network pharmacology and molecular docking. Screen the components and targets of the AM-AS compound in the TCMSP and the BATMAN-TCM, and establish a component-target interaction network by Cytoscape 3.7.
View Article and Find Full Text PDFEcotoxicol Environ Saf
October 2021
Denitrifying biofilm promises to be very useful for remediation of nitro-aromatic compounds (NACs) and nitrates in wastewater. Little is known about the role of extracellular polymeric substances (EPS) in nitrobenzene (NB, a typical NAC) remediation, despite the indispensability of EPS for biofilm formation. Herein, the significance of the mechanistic role of EPS in the response of denitrifying biofilms to various levels of NB was investigated.
View Article and Find Full Text PDFAttapulgite (ATP) has a unique porous layered chain structure and is an excellent environment-friendly decolorizer. However, its high viscosity makes it difficult to separate. First, it was combined with magnetic FeO nanoparticles to obtain FeO-ATP that is easy to recycle and reuse.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2021
Although domestic wastewater and its reclaimed water are alternative water resources in arid region, investigation of their negative effect must be done to prevent environmental pollution. In this paper, a short-term column experiment was conducted to simulate the infiltration process of wastewater in desert soil. Alfalfa was planted and irrigated with fresh water for control (CK), tertiary treated domestic wastewater (TTW), secondary treated domestic wastewater (STW) and raw domestic wastewater untreated (RW).
View Article and Find Full Text PDFEnviron Pollut
April 2020
Via the thermal sintering, a nanocrystalline IrO coating was formed on the Ti substrate to successfully prepare a Ti/IrO electrode. Based on the electrochemical analysis, the prepared Ti/IrO electrode was found to have powerful oxidation effect on the organics in the TNT red water, where the nitro compound was oxidized through an irreversible electrochemical process at 0.6 V vs.
View Article and Find Full Text PDF