Publications by authors named "Kun Ran"

Article Synopsis
  • Phenolic compounds are key secondary metabolites in plants, and this study analyzed the phenolic profiles and antioxidant activity of five pear cultivars and tea leaves using advanced mass spectrometry techniques.
  • Significant differences were found in both the quantity and composition of phenolic metabolites between pear and tea leaves, with the Yali cultivar showing the highest total phenol content and antioxidant activity.
  • Specific phenolic compounds were identified as unique to each pear variety, and many metabolites were linked to pathways related to flavonoid and phenylpropanoid biosynthesis, offering insights for future pear leaf resource development.
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Background: Plant diseases caused by pathogenic fungi are devastating. However, commonly used fungicides are harmful to the environment, and some are becoming ineffective due to fungal resistance. Therefore, eco-friendly biological methods to control pathogenic fungi are urgently needed.

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Objectives: Bare stent treatment and bare stent-assisted coiling treatment have not been directly compared in symptomatic isolated superior mesenteric artery dissection with a patent false lumen. Thus, we compared the early and mid-term outcomes of bare stent treatment and bare stent-assisted coiling treatment to determine the most effective remedy for patients with this condition.

Methods: Consecutive patients diagnosed with systematic isolated superior mesenteric artery dissection with a patent false lumen admitted to the study hospital between January 2016 and December 2021 were enrolled in this retrospective study.

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Introduction: Surgeons may experience physical and mental health problems because of their jobs, which may lead to chronic muscle damage, burnout, or even withdrawal. However, these are often ignored -holder assistants during laparoscopic surgery. We aimed to analyze the differences between operating surgeons and camera-holder assistants.

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The development of structurally stable, highly conductive layered materials as cathode materials for aqueous zinc-ion batteries (AZIBs) is essential. Herein, polyaniline (PANI) was inserted into the interlayer of a vanadium-metal-organic framework-derived VO to take advantage of the selective growth of the (110) crystal plane of VO, facilitating sufficient diffusion of aniline within the VO interlayer along the vertical direction of the spatial c-axis while stabilizing the interlayer structure. The synthesized composite (PANI80-VO) exhibited excellent electrochemical properties owing to the increase in the material layer spacing from 5.

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Two new polyketides versicolorones A-B (1-2), one new diketopiperazine derivative aspergiamide B methyl ester (3), along with twenty known compounds 4-23, were obtained from the EtOAc extract of the Cordyceps-colonizing fungus Aspergillus versicolor ZJUTE2. The structures of 1-3 were established by detailed interpretation of the spectroscopic data and their absolute configurations were established by comparative analyses of the calculated and experimental ECD spectra. In the in-vitro bioassay, compounds 8 and 21 exhibited significant inhibitory activity against the Escherichia coli β-glucuronidase (EcGUS) with IC values of 54.

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Objective: In this study, we present our early outcomes of cyanoacrylate ablation (CA) versus endovenous laser ablation (EVLA) for the treatment of great saphenous vein (GSV) insufficiency in the Chinese mainland population.

Methods: We retrospectively analyzed 108 patients (53 patients in the CA group and 55 patients in the EVLA group) with GSV insufficiency who were treated with CA and EVLA between May 2020 and May 2021. The Venous Clinical Severity Score and Aberdeen Varicose Vein Questionnaire were used to assess clinical symptoms and quality of life, respectively.

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Boron (B) is a required micronutrient that is crucial for the growth and development of vascular plants. A deficiency in B is generally regarded as a limiting factor affecting agricultural production in many parts of the world. Boron is involved in the metabolism of plant lignin and additionally, B deficiency can lead to the excessive accumulation of lignin in plant leaves/roots, resulting in corking symptoms and inhibited growth.

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Article Synopsis
  • Melatonin (MT) is a substance used to help keep fruits fresh longer and prevent them from getting bad too quickly.
  • The best amount of MT found to use for the fruit 'Xinli No.7' is 150 μM, which helps keep the fruit fresh for up to 60 days at a cool temperature.
  • MT not only helps improve the fruit's taste and smell but also affects many genes that are important for keeping the fruit healthy while it is stored.
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α-Glucosidase (AGS) is a therapeutic target for Type 2 diabetes mellitus (T2DM) that tends to complicate with other diseases. Some medications for the treatment of T2DM complications have the risk of inducing severe adverse reactions such as diarrhea via the metabolism of intestinal bacterial β-glucuronidase (BGUS). The development of new AGS and/or BGUS inhibitors may improve the therapeutic effects of T2DM and its complications.

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Methylglyoxal (MG) is a novel signaling molecule with multiple functions in plants. To explore the effects of MG on Chinese chestnut () under drought stress, two-year-old 'Huangpeng' chestnut seedlings were treated with 15% polyethylene glycol (PEG) coupled with MG or its scavenger N-acetyl-L-cys-teine (NAC). We measured the activities of antioxidant enzymes, including superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), ascorbate peroxidase (APX) and glutathione reductase (GR), and glyoxalase enzymes, including glyoxalase Ⅰ (GlyⅠ) and glyoxalase Ⅱ(GlyⅡ).

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Four undescribed regular rosane-type diterpenoids euphominoids M-P and three undescribed rearranged rosane-type diterpenoids euphomilones C-E were isolated from the whole plants of Euphorbia milii Des Moul., along with nine known compounds. Their structures were elucidated by detailed interpretation of the NMR and mass spectroscopy.

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Background: NAC transcription factors play important roles in the regulation of plant growth, development, abiotic and biotic stress responses. The transcriptional level of s in different tissues and under various biotic and abiotic stress treatments was determined to provide a solid foundation for studying the function of s.

Methods: Thirty-two full-length cDNA sequences of s were isolated by homologous comparison and RT-PCR confirmation, and the obtained cDNA sequences and the deduced amino acid sequences were analyzed with bioinformatics methods.

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Background: AP2/ERF transcription factors are involved in the regulation of plant growth, development, and stress responses. Our research objective was to characterize novel apple ( × Borkh.) genes encoding AP2/ERF transcription factors involved in regulation of plant growth, development, and stress response.

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Proliferation of vascular smooth muscle cells (VSMCs) plays an important role in various vascular diseases. Abnormal hemodynamic factors are important stimulus for promoting proliferation of VSMCs. In this study, we show that transmural pressure (TP) promotes the proliferation of human arterial smooth muscle cells (HASMCs) and its related mechanism.

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Ovate family proteins (OFPs), which are involved in aspects of plant development and growth, is a class of plant-specific transcription factors. Although OFPs have been reported in some species, little is known about their evolution, structure, fruit developmental expression, and interactions among OFP members in peach (Prunus persica). In this study, 15 peach OFP (PpOFP) genes were identified.

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The plant growth-promoting rhizobacterium strain Lzh-a42, which has antimicrobial activity, was isolated from tomato rhizosphere. Here, we report its genome sequence, which includes several predicted functional genes related to secondary metabolite biosynthesis, antimicrobial activity, and biofilm synthesis.

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Objective: To evaluate the efficacy and safety of drug-coated balloon (DCB) angioplasty versus uncoated balloon (UCB) angioplasty in treatment of lower extremity arterial occlusive disease (LEAOD).

Methods: Randomized controlled trial comparing DCB and UCB angioplasty for treatment of LEAOD were searched in online databases. Literature screening and quality assessment was carried out according to the established inclusion criteria and exclusion criteria.

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Abscisic acid (ABA) biosynthesis has been widely characterized in plants, whereas the effects of ABA biosynthesis on nitric oxide (NO) generation in osmotic stress are less well understood. In this study, Malus hupehensis Rehd. 9-cis-epoxycarotenoid dioxygenase gene (MhNCED3) which is the key gene in ABA biosynthesis was transformed into wild type (WT) and 129B08/nced3 mutant (AtNCED3 deficient), respectively, and two transgenic Arabidopsis lines were obtained.

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High Cl(-) concentrations in tissues can be toxic to crop plants and may lead to reduced growth rates and yields. 9-cis-epoxycarotenoid dioxygenase (NCED) is thought to be involved in the biosynthesis of abscisic acid (ABA), which is an important regulator of plant adaptive responses to stress. Here, the expression of MhNCED3 in Malus hupehensis Rehd.

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Vacuolar processing enzymes (VPEs) have received considerable attention recently, as they exhibit caspase-1-like cleavage activity and regulate the process of PCD. However, knowledge about their detailed characteristics and structures is relatively limited. In this study, a gamma vacuolar processing enzyme gene, MhVPEγ, has been isolated from the leaves of Malus hupehensis (Ramp) Rehd.

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A pilot-scale hybrid process of ozone and biological aerated filters (BAF) with the capacity of 36 t x d(-1) was applied for advanced treatment of the secondary biologically effluent from a dyeing and tannery park wastewater treatment plant. The pollutants removal performance along the height of different medias BAFs were investigated. The results showed that the average COD and color were 55.

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Taking two-year old Malus hupehensis as test material, this paper studied its root nitric oxide (NO) production under waterlogging, and the effects of exogenous NaNO3 on this production. Waterlogging for 3-9 days promoted the NO production significantly. Within the 12 days of waterlogging, the NO production, nitrite reductase (NR) and nitric oxide synthase (NOS) activities, and malondialchehyche (MDA) content in roots increased first, and decreased subsequently.

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