FSP1 reduces exogenous coenzyme Q10 and inhibits ferroptosis to alleviate intestinal ischemia-reperfusion injury.

Introduction: Intestinal ischemia-reperfusion injury (IRI) is a critical condition often requiring emergency intervention. Ferroptosis, a form of regulated cell death driven by phospholipid peroxidation, plays a central role in its pathogenesis.

Objective: This study aimed to explore whether CoQ10 could mitigate intestinal IRI by suppressing ferroptosis.

Topological prethermal strong zero modes on superconducting processors.

Symmetry-protected topological phases cannot be described by any local order parameter and are beyond the conventional symmetry-breaking model. They are characterized by topological boundary modes that remain stable under symmetry respecting perturbations. In clean, gapped systems without disorder, the stability of these edge modes is restricted to the zero-temperature manifold; at finite temperatures, interactions with mobile thermal excitations lead to their decay.

Probiotics in inflammatory bowel diseases: emphasis on mechanisms and clinical application.

Inflammatory bowel disease (IBD) is a group of diseases characterized by chronic intestinal inflammation including Crohn's disease (CD) and ulcerative colitis (UC). In recent years, probiotics have attracted more and more attention as a potential adjuvant therapy. Probiotics can improve the symptoms and quality of life of IBD patients mainly by regulating intestinal microflora, regulating immune response, enhancing intestinal barrier function and exerting anti-inflammatory effect.

Efficient 2.8-µm Er-doped all-fiber laser based on a low optical feedback cavity.

Mid-infrared (mid-IR) fiber lasers have faced significant challenges in achieving all-fiberized structure with high efficiency and high output power due to the limitations of conventional cavity designs. In this paper, we introduce what we believe to be a novel 2.8 µm all-fiber laser configuration with a low optical feedback linear cavity, effectively eliminating the need for traditional high-reflector components.

Measuring metric stretching in an accelerated reference frame via a Michelson interferometer with high-order Bessel-Gaussian beams.

We analyze a Michelson interferometer with Bessel-Gaussian vortex beams, where acceleration of the reference frame perturbs the interference pattern of the two Bessel-Gaussian vortices with opposite topological charges. The reversal of topological charge in one arm is due to the vortex phase-conjugating mirror being composed of two double passes through the cylindrical lens. The tiny changes of the space metric are time dependent.

Programmable 2D photonic quasicrystals with real-time reconfigurability.

We demonstrate a programmable approach to generate 2D photonic quasicrystals (PQCs) with real-time reconfigurability. By encoding complex amplitude onto the spatial light modulator (SLM), we directly emulate tunable PQC lattices, where the engineered diffractive patterns define the PQC structure. This approach enables real-time switching (60 Hz) between diverse PQC lattices with up to 26-fold rotational symmetry, tailorable orbital angular momentum (OAM), and distortion control.

Correction: Life-safety disparity index: a comprehensive, valid, and reliable tool to assess Chinese people's life-safety performance.

[This corrects the article DOI: 10.3389/fpubh.2025.

Microsphere Probe-Assisted Trapping and Enhancement of Interlayer Excitons in WSe/MoSe Heterostructures under Ultralow Pressure.

Interlayer excitons, bound states of electrons and holes residing in opposite layers of a heterostructure, are vital for the optical properties of van der Waals semiconducting heterostructures. Effective mechanical control of interlayer excitons in van der Waals heterostructures is crucial for fundamental research and optoelectronic applications. However, existing techniques face challenges in simultaneously achieving high-precision mechanical loading on microscale heterostructure samples and detecting enhanced excitonic response therein.

Too Fast for Spin Flipping: Absence of Chirality-Induced Spin Selectivity in Coherent Electron Transport through Single-Molecule Junctions.

Chirality-induced spin selectivity (CISS), which refers to the ability of chiral molecules to preferentially select spins during electron transfer, has attracted great attention during the past two decades. However, the theoretical and experimental understanding of the CISS effect remains preliminary. In this study, we demonstrate that there is no distinguishable CISS effect in the case of coherent electron transport through single chiral molecular junctions for a set of four molecule studied here.

Life-safety disparity index: a comprehensive, valid, and reliable tool to assess Chinese people's life-safety performance.

Aims: In order to accurately and quantitatively grasp the current situation and trend of Chinese people's life-safety performance and to provide scientific basis and suggestions for the government, scientific research institutions, enterprises and the public to do a good job in life-safety protection.

Methods: The establishment process of life-safety disparity index (LDI) included six steps, including (i) concept building (ii) framework formulation; (iii) indicator selection; (iv) database building; (v) weight determination; and (vi) LDI scores calculation. The indicator scheme for LDI based on this framework was constructed after multiple rounds of panel discussions with our expert advisory committee.

A novel function for the transcription factor sensitive to proton rhizotoxicity1 in promoting anthocyanin accumulation in strawberry.

Sensitive to proton rhizotoxicity1 (STOP1), a C2H2-type zinc finger transcription factor, has been widely studied as a core transcription factor in adapting plants to diverse environmental stresses. However, whether STOP1 regulates anthocyanin accumulation in plants is still unknown. This study identified the FvSTOP1 in woodland strawberry.

Elucidating Charge Carrier Reactivity, Conversion, and Degradation in n-Doped Oligo- and Poly(benzodifurandione).

n-Doped poly(benzodifurandione) (n-PBDF) has gained significant attention due to its solution processability and high electrical conductivity. However, the nature of charge carriers in n-PBDF remains poorly understood. In this study, we investigated a series of oligo(benzodifurandiones) (BFD1, BFD2, and BFD3), using previously reported BFD1 and BFD2 alongside newly synthesized BFD3, with a particular focus on the charged species of BFD3.

Comparison of pancreaticojejunostomy under the theory of mucosal priority healing with duct-to-mucosa anastomosis and invagination pancreaticojejunostomy after pancreaticoduodenectomy: A single-centre case-control study.

ObjectiveThe technological aspects of pancreaticoduodenectomy have progressed greatly, but the risk of postoperative complications, especially postoperative pancreatic fistula (POPF), postpancreatectomy haemorrhage (PPH) and mortality, is high. Therefore, we aimed to explore the safety and feasibility of pancreaticojejunostomy (PJ) under the mucosal priority healing theory through a case-control study.MethodsWe have described in detail PJ under the theory of preferential mucosal healing (PM-PJ).

The FvMYB17 targets FvDHQS to promote ellagic acid biosynthesis in strawberry.

Subgroup 4 R2R3-MYB factors are known to act as MYB repressors of phenylpropanoid metabolism in most plant species. However, whether these MYB repressors regulate other plant secondary metabolisms, such as ellagic acid, remains unclear. Additionally, the mechanism by which some MYB repressors function as activators remains unknown.

FvbHLH78 interacts with FvCRY2 to promote flowering in woodland strawberry.

Flowering is a crucial agricultural trait of strawberries. While the bHLH family comprises numerous members in plants, its function in controlling strawberry flowering remains largely unexplored. In this study, FvbHLH78 was found to be highly expressed in the shoot apices and ripening fruits of woodland strawberry (Fragaria vesca).

4.5 W Er-doped ZBLAN fiber laser at 3.78 μm.

In this work, we demonstrate an efficient long-wavelength operation of an Er-doped ZBLAN fiber laser in the 3.5 μm band with F→I transition. A high-transmission bandpass filter (BPF) is employed in the laser cavity to select a specific lasing wavelength of around 3.

Dimensionality-Controlled Confinement Effects for Tunable Optoelectronic Properties in Quasi-1D Hybrid Perovskites.

Hybrid perovskite dimensional engineering enables the creation of one- to three-dimensional (1D to 3D) networks of corner-sharing metal halide octahedra interspersed by organic cations, offering opportunities to tailor semiconducting properties through quantum- and dielectric-confinement effects. Beyond the discrete options, intermediate dimensionality has been introduced in the form of quasi-2D phases with inorganic layers of varying thickness. The current study extends this approach to quasi-1D lead-iodide systems with variable ribbon widths from 2 to 6 octahedra, stabilized by flexible molecular configurations, cation mixing of organic cations, or guest molecule selection.

Enhancing the Thermoelectric Performance of n-Type PbTe via Mn Doping.

Significant strides have been made in enhancing the thermoelectric properties of p-type PbTe alloys, whereas the thermoelectric performance of n-type alloys lags behind that of p-type alloys, primarily owing to the difficulty of improving their Seebeck coefficient via band convergence. In this work, Mn was introduced into the n-type PbSbTe alloy, and Mn doping increases the absolute value of the Seebeck coefficient significantly by increasing the effective mass and reducing carrier concentration, resulting in a higher power factor of 20.8 μW/Kcm being achieved for 0.

Ubiquitin-mediated degradation of the inhibitor FvMYB1 and the activator FvBBX20 by FvCSN5 balances anthocyanin biosynthesis in strawberry fruit.

Plant CSN5 is widely recognized as the subunit of the COP9 signalosome and CSN5 is mainly involved in plant growth and development, and tolerance to biotic and abiotic stresses. However, the molecular mechanism of CSN5 regulating anthocyanin biosynthesis in plants is still largely unknown. Here, we identified FvCSN5 from the woodland strawberry yeast two-hybrid library using the anthocyanin pathway inhibitor MYB1 as bait.

Chemical and sensory properties of young cabernet sauvignon and marselan wines from subregions on the eastern foothills of helan mountains in ningxia, China: Terroir effect.

This study aimed to analyze the characteristics of Cabernet Sauvignon (CS) and Marselan (M) wines from different subregions on the eastern foothills of Helan Mountain. UHPLC-ESI-Q-ToF and HS-SPME-GC-MS were employed to analyze the metabolic properties of the wines, and QDA was combined for sensory characterization. The results indicated that chromaticity, total phenols, ethyl isobutyrate, n-decanoic acid, (-)-epigallocatechin, and epigallocatechin were key indicators for distinguishing CS wines from different subregions, whereas total acids, total phenols, hexanol, ethyl butyrate, protocatechuic acid, and (+)-catenin were key indicators for distinguishing M wines from different subregions.

Monolayer MoS with S vacancy defects doped with Group V non-metallic elements (N, P, As): a first-principles study.

Context: This study systematically investigated the effects of single S-atom vacancy defects and composite defects (vacancy combined with doping) on the properties of MoS using density functional theory. The results revealed that N-doped S-vacancy MoS has the smallest composite defect formation energy, indicating its highest stability. Doping maintained the direct band gap characteristic, with shifts in the valence band top.

High-Energy-Density Li-CO Battery at Elevated Temperatures: Advances with Fluorine-Substituted Graphdiyne and Ionic Liquid.

Li-CO batteries demonstrate promising prospects in terms of high-density energy storage and efficient CO fixation. However, their practical application is impeded by sluggish reaction kinetics and leakage of volatile and flammable organic electrolytes, especially for high temperature application scenarios, leading to large polarization and limited cycling stability. Herein, we fabricate a highly rechargeable and stable Li-CO battery with high temperature adaptability by employing fluorine-substituted graphdiyne (FGDY) as cathode catalysts and imidazolium-based ionic liquid as electrolyte solvents.

Thermally Stable Anthracene-Based 2D/3D Heterostructures for Perovskite Solar Cells.

Bulky organic cations are used in perovskite solar cells as a protective barrier against moisture, oxygen, and ion diffusion. However, bulky cations can introduce thermal instabilities by reacting with the near-surface of the 3D perovskite forming low-dimensional phases, including 2D perovskites, and by diffusing away from the surface into the film. This study explores the thermal stability of CsFAPbI 3D perovskite surfaces treated with two anthracene salts─anthracen-1-ylmethylammonium iodide (AMAI) and 2-(anthracen-1-yl)ethylammonium iodide (AEAI)─and compares them with the widely used phenethylammonium iodide (PEAI).

Three transmission properties of the perfect vortex beam.

We propose that a perfect vortex beam (PVB) exhibits three major properties, namely, perfect property, self-focusing property, and self-healing property. Our experimental results indicate that PVB manifests superb perfect property, impervious to the influence of orbital angular momentum during the anti-diffraction stage, but ultimately transitioning to the self-focusing property during the self-focusing stage. The self-focusing property of PVB can significantly augment its transmission performance and be tailored through adjustments to the ring radius, ring thickness, and self-focusing ratio to meet the needs of various optical applications.

The role of ischaemia-modified albumin in the prognosis of acute pancreatitis and its correlation with the NF-B-mediated inflammatory response.

Objective: To investigate the correlation between the serum levels of ischaemia-modified albumin (IMA) and disease severity in rats with acute pancreatitis (AP).

Methods: A rat AP model was established and blood samples from each group were analysed at different time points. After the experiment, the pancreatic tissues of the rats were collected for pathological examination and the measurement of protein levels of NF-κB and NF-κB p65.