Hypoxia represents a critical environmental stressor in aquaculture, significantly disrupting aquatic organisms' physiological homeostasis and thereby constraining the sustainable development of aquaculture industries. To elucidate the mechanisms underlying hypoxia-induced metabolic regulation in aquatic species, this study employed hybrid yellow catfish ( ♀ × ♂) as a model organism to systematically investigate the multidimensional physiological responses in brain, liver, and muscle tissues under hypoxia (0.7 mg/L) and reoxygenation (7.
View Article and Find Full Text PDFBackground: Anxiety disorders (ADs) and depressive disorders (DDs) are prevalent among older adults with non-communicable diseases (NCDs), yet nationally representative epidemiological data from China remain limited. This study, as a part of the 2013-2015 China Mental Health Survey (CMHS), aimed to assess the prevalence of ADs and DDs and identify associated factors among older adults with NCDs in China.
Method: A total of 5,428 patients aged 60 years and above with reported NCDs were selected from the CMHS.
Public Health Nutr
August 2025
Objective: To assess the association between coffee consumption and life expectancy among the US adults.
Design: Prospective cohort.
Setting: National representative survey in the United States, 2001-2018.
Background: Emerging evidence underscores the critical involvement of ferroptosis in the pathophysiology of AKI. However, the role of ferroptosis-related genes (FRGs) in AKI remains insufficiently explored. This study sought to identify potential FRGs associated with AKI through bioinformatics approaches and experimental validation.
View Article and Find Full Text PDFBackground: Mental disorders among the elderly are a growing public health concern contributing significantly to disease burden, disability, and mortality. However, there is a lack of nationally representative studies examining the prevalence and correlates of mental disorders among older adults in community settings. Considering 55 years old is the beginning of "young old", our study targets the population of adults aged 55 years old and above.
View Article and Find Full Text PDFWith the rapid growth of active distribution networks, the demand for intelligent and flexible operation has increased significantly [...
View Article and Find Full Text PDFSafflower ( L.) seeds, rich in triacylglycerols, have poor fatty acid-to-sugar conversion during storage, affecting longevity and vigor. Previous experiments have shown that the aging of safflower seeds is mainly related to the impairment of energy metabolism pathways such as glycolysis, fatty acid degradation, and the tricarboxylic acid cycle.
View Article and Find Full Text PDFFalls are common during stroke rehabilitation, leading to physical injuries and psychosocial consequences. While prior studies have explored the association between falls and life satisfaction, the effect of fall-related injury severity remains unclear. This multicenter cross-sectional study included 6,068 stroke inpatients undergoing rehabilitation.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
August 2025
Objective: Placenta accreta spectrum (PAS) disorders are a series of gestational diseases, with severe adverse outcomes. Apolipoprotein A1 (APOA1) is a lipid molecule that plays a role in cell invasion, inflammation and immune response. This study aimed to elucidate the relationship between APOA1 and PAS, as well as its adverse outcomes.
View Article and Find Full Text PDFBackground: Brominated flame retardants (BFRs) are endocrine-disrupting contaminants; however, the impact of BFR mixtures on sex steroid hormone levels in adults remains unclear.
Methods: This study included 2513 male and female adults from the 2013-2016 National Health and Nutrition Examination Survey (NHANES). Weighted linear regression was employed to examine the associations between individual BFR exposures and total testosterone(TT), estradiol(E2), sex hormone binding globulin (SHBG), free androgen index (FAI), and TT/E2.
Aims: To report the prevalence and correlates of anxiety disorders among the elderly population in China; and to describe functional impairment and mental health service utilization due to anxiety disorders.
Methods: Data were derived from the Chinese Mental Health Survey. Weighted prevalence rates of various anxiety disorders were calculated.
Background: Newborns with low-birth-weight may lag behind those with normal-birth-weight in terms of growth, development, and nutritional status, which increases mothers' concerns about the child's future health and leads to anxiety and depression. Providing nutritional support to newborns with low-birth-weight to facilitate optimal growth and development may help alleviate maternal anxiety and depression.
Aim: To explore the effects of nutritional support timing on the growth and development of newborns born under 2 kg and their mothers' anxiety and depression.
Metal-organic frameworks (MOFs), known for their high porosity and tunable properties, have attracted significant interest in enhancing the sensitivity and functionality of plasmonic optoelectronic devices. However, their application in surface plasmon resonance (SPR) fiber-optic sensors remains challenging due to difficulties in the preparation and transfer of large-area two-dimensional (2D) MOFs. Here, a large-area continuous ultrathin MOF film was successfully fabricated using an interfacial synthesis strategy and seamlessly adhered to the tilted fiber Bragg gratings (TFBG).
View Article and Find Full Text PDFFront Cell Infect Microbiol
July 2025
[This corrects the article DOI: 10.3389/fcimb.2017.
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2025
Sorption-based atmospheric water harvesting (SAWH) offers a promising solution to address freshwater scarcity. Although many solid sorbents exhibit high water uptake capacities, their ability to achieve continuous, all-day water production still depends on complex system configurations. Here, a 24-h SAWH system is presented, enabled by wood-based ionogel (WIG) with simultaneous sorption-desorption functionality.
View Article and Find Full Text PDFMicroRNAs (miRNAs) serve as critical biomarkers for cancer diagnosis and disease monitoring due to their dysregulated expression in malignancies. However, their low abundance, short length, and high sequence similarity pose significant detection challenges. Here, we present a plasmonic sensing platform that integrates Au@ZIF-8 core-shell nanostructures with a gold-coated tilted fiber Bragg grating surface plasmon resonance sensor.
View Article and Find Full Text PDFThis study aimed to explore the effects and mechanism of the combination of germination and moderate milling in changing the texture and starch digestion of brown rice (BR). For nutritional profile, the moisture and fat contents decreased in germinated BR (GBR), while further moderate milling (degree of milling, DOM at 1 % and 2 %) increased starch but decreased γ-GABA and vitamin B1 in GBR. Notches and structural damages were observed in GBR and GBR-DOM samples via SEM.
View Article and Find Full Text PDFBiomass materials have been widely used in various industries to achieve a carbon-neutral and sustainable society. Here, we show a heterogeneous corn-based precursor strategy that transforms low-value agricultural waste into structural air filters composed of alternating microfibers (2.61 ± 1.
View Article and Find Full Text PDFNPJ Syst Biol Appl
July 2025
Antibiotic treatment is widely used for gastrointestinal diseases, often leading to drug resistance. However, the underlying mechanisms of drug resistance remain unclear. Mathematical modeling provides a powerful tool to explore the dynamics of antibiotic resistance, yet few models have considered the effect of biological noise, which originates from microscopic interactions between bacteria.
View Article and Find Full Text PDFGram-negative bacteria assemble an asymmetric outer membrane (OM) that functions as an effective barrier against antibiotics. Building a stable and functional OM requires the assembly and maintenance of balanced levels of proteins, lipopolysaccharides, and phospholipids into the bilayer. In , the trans-envelope Tol-Pal complex has recently been established to play a primary role in maintaining OM lipid homeostasis.
View Article and Find Full Text PDFBackground: Acne is a common, multifactorial skin condition with significant psychosocial and public health impacts. However, its burden among reproductive-age women remains underexplored.
Methods: Using Global Burden of Disease (GBD) 2021 data, we analyzed acne incidence, prevalence, and disability-adjusted life years (DALYs) in females aged 15-49 across 204 countries (1990-2021).
Background/aim: This study aims to elucidate whether Macranthoside B (MB) intensifies paclitaxel (PTX)-induced apoptosis in human cervical adenocarcinoma HeLa cells as well as the underlying mechanisms.
Materials And Methods: The MTT assay was used to test the HeLa cell viability after MB and PTX co-treatment, and colony formation assay was utilized to evaluate cell proliferation. Reactive oxygen species (ROS) and mitochondrial membrane potential (MMP) were analyzed by flow cytometry.
Adjusting the tax distribution relationship among governments at all levels in the reform of the fiscal and taxation system will inevitably trigger changes in local government fiscal revenue. Will the fiscal pressures accompanying such changes have a significant impact on the expenditure decisions of local governments? Drawing on the 2002 Income Tax Sharing Reform in China as a quasi-natural experiment, we apply an intensity difference-in-difference methodology to evaluate how fiscal pressure influence county-level education provision. The empirical evidence indicates that counties most exposed to the reform experienced a marked reduction in the proportion of fiscal expenditure devoted to education, with the impact exhibiting a lagged and persistent pattern.
View Article and Find Full Text PDFAcute lung injury (ALI) is the most serious complication of sepsis, but there is currently a lack of effective treatment methods. Therefore, finding drugs to treat sepsis induced acute lung injury (SALI) is an urgent clinical problem that needs to be solved. Kaempferol has been proven to have therapeutic effects on various lung diseases.
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