Lactiplantibacillus pentosus YXJ 1401 combats multidrug-resistant Salmonella Enteritidis: Antibacterial activity, dairy preservation, and metabolomics.

The antibacterial activity, dairy biopreservative potential, and antibacterial compounds of the lactic acid bacterium Lactiplantibacillus pentosus remain largely unexplored. In this study, we investigated the antibacterial activity of L. pentosus YXJ 1401 isolated from food-grade traditional Chinese pickles.

A nomogram based on clinical and ultrasound features to identify sub-1 cm benign and malignant thyroid lesions.

BackgroundA non-invasive and reliable method is essential for diagnosing sub-1 cm thyroid lesions.ObjectiveWe have developed a nomogram that integrates ultrasound features and clinical risk factors to effectively diagnosed sub-1 cm thyroid lesions.MethodsOur study included 406 patients with sub-1 cm thyroid lesions.

Sleep duration and overactive bladder syndrome in US adults: a propensity score matching cohort study using NHANES 2005-2018.

Objective: The association between sleep duration and overactive bladder (OAB) risk remains underexplored. The aim of this study was to assess this relationship in U.S.

Utility of endometrial multi-vessel blood flow ultrasound parameters in predicting pregnancy outcomes.

Objectives: To evaluate the endometrium using multi-vessel blood flow ultrasound parameters and explore their potential utility in predicting pregnancy outcomes.

Methods: A total of 205 women were included in the study. Transvaginal three-dimensional ultrasound was used to evaluate luteal phase endometrial thickness, volume, and three-dimensional power Doppler blood flow parameters of the endometrium (vascularization index [VI], flow index [FI], and vascularization flow index [VFI]), as well as the endometrial microvascular vascularization index (VI).

Low-valent Cu doping optimizes Ruddlesden-Popper perovskite for accelerated levofloxacin removal: Enhanced Ni-dominated dual radical/nonradical pathways.

Ruddlesden-Popper (R-P) perovskites have emerged as superior candidates for peroxymonosulfate-based advanced oxidation processes (PMS-AOPs) due to their tunable electronic configurations and enhanced electron transfer kinetics. Although metal doping has been extensively studied as the most common catalyst modification strategy in PMS activation processes, systematic identification of the dominant metal species in doped systems remains lacked. In this work, copper-doped R-P perovskite (LaSrNiCuO, LSNC) was employed to investigate the influence of B-site ion electronic environment evolution on reactive oxygen species (ROS) generation during PMS activation, with the dominant metal species being determined through combined density functional theory (DFT) calculations and characterization.

Molecular Targeting of Intracellular Bacteria by Homotypic Recognizing Nanovesicles for Infected Pneumonia Treatment.

Although extensive antibiotic regimens have been implemented to address pathogen-infected pneumonia, existing strategies are constrained in their efficacy against intracellular bacteria, a prominent contributor to antibiotic resistance. In addition, the concurrent occurrence of a cytokine storm during antibiotic therapy presents a formidable obstacle in the management of pneumonia caused by pathogens. In the present study, an infection-targeting system that leverages M2-macrophage-derived vesicles [exosomes (Exos)] as vehicles to convey antibiotics (antibiotics@Exos) was developed for effective pneumonia management.

Development and validation of a dynamic nomogram for predicting central lymph node metastasis in papillary thyroid carcinoma patients based on clinical and ultrasound features.

Background: Prophylactic cervical lymph node dissection (CLND) for patients with papillary thyroid carcinoma (PTC) has long been a subject of controversy. To accurately perform preoperative staging and risk stratification of PTC patients, this study developed and validated a preoperative nomogram model for predicting central lymph node metastasis (CLNM) based on clinical and ultrasound features, thereby guiding surgical resection and postoperative adjuvant therapy.

Methods: Patients with PTC (n=409), as confirmed by surgery and histopathology combined with CLND, were divided into training and validation groups.

Neurofilament light chain levels in neuronal surface antibody-associated autoimmune encephalitis: a systematic review and meta-analysis.

Background: Neuronal surface antibody-associated autoimmune encephalitis (NSAE) is a group of neuro-inflammatory disorders that is mediated by autoantibodies against the cell-surface and synaptic antigens. Studies have explored the role of neurofilament light chain (NfL) in NSAE and provided inconsistent data. We performed a systematic review and meta-analysis to evaluate the NfL levels in the serum and cerebrospinal fluid (CSF) of patients with NSAE.

[Construction of Key Technology System for Mine Ecological Restoration Under System Perspective].

Mine ecological restoration has experienced a long-term development process in China, in which various technologies have been constantly developing and integrating. Based on the related theoretical research and field program, the technical system of mine ecological restoration was constructed, and the characteristics of key technologies were specifically grasped. In this research, the environment, including natural elements and the spatial environment, is the object of mine ecological restoration, which requires further long-term investigation and monitoring.

Characterization of metabolic profile of Dazhu Hongjingtian and evaluation of its anti-hypoxic constituents.

Dazhu Hongjingtian (DZ) is renowned for its diverse pharmacological activities, yet its metabolic pathways remain to be fully elucidated. In this study, the metabolic profile after oral administration of DZ extract (DZE) in rats was systematically identified by the UPLC/Q-TOF-MS/MS method for the first time. A total of 94 components, including 32 prototypes and 62 metabolites, were tentatively characterized in rat plasma and various tissues samples.

Zhuangyao Jianshen Wan ameliorates senile osteoporosis in SAMP6 mice through Modulation of the GCN5L1-mediated PI3K/Akt/wnt signaling pathway.

Background: Senile osteoporosis (SOP) is a systemic bone disease characterized by increased susceptibility to fractures. However, there is currently no effective treatment for SOP. The Zhuangyao Jianshen Wan (ZYJSW) pill is traditionally believed to possess kidney-nourishing and bone-strengthening effects, demonstrating efficacy in treating fractures.

 (Cypriniformes, Cyprinidae), a new cave fish with extremely small population size from western Guizhou, China.

This study describes a new species, ., discovered within a cave located in Hongguo Town, Panzhou City, Guizhou Province, southwestern China, with the type locality in the Nanpanjiang River basin. Phylogenetic trees reconstructed based on mitochondrial genes show that the new species represents an independent evolutionary lineage with large genetic differences, 1.

Complete mitochondrial genome of Horváth, 1911 (Heteroptera: Saldidae) and phylogenetic analysis.

The complete mitochondrial genome of (Heteroptera: Saldidae) is 16,049 bp in length, comprising 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNAs), 2 ribosomal RNA genes (rRNAs) and a control region. All the PCGs are initially encoded by ATN, TTG or GTG, and terminated coding with TAA or a single T. With the exception of , all tRNAs exhibit a typical cloverleaf secondary structure.

The complete mitochondrial genome of Zhang, Li & Qi, 2008 (Hemiptera: Cicadellidae: Eurymelinae: Idiocerini).

In this study, the complete mitochondrial genome of was sequenced and annotated for the first time, which belongs to the subfamily Eurymelinae. The mitogenome of was 15,267 bp in length and contained 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNAs), two ribosomal RNA genes (rRNAs), and one non-coding control region. In this mitogenome, all the PCGs are initially encoded by ATT, ATA, ATG, or TTG, and terminated by TAA, or single T.

Multimodal data integration using machine learning to predict the risk of clear cell renal cancer metastasis: a retrospective multicentre study.

Purpose: To develop and validate a predictive combined model for metastasis in patients with clear cell renal cell carcinoma (ccRCC) by integrating multimodal data.

Materials And Methods: In this retrospective study, the clinical and imaging data (CT and ultrasound) of patients with ccRCC confirmed by pathology from three tertiary hospitals in different regions were collected from January 2013 to January 2023. We developed three models, including a clinical model, a radiomics model, and a combined model.

Electrochemistry-assisted in-situ regeneration of oxygen vacancies and Ti(III) active sites for persistent uranium recovery at a low potential.

Electrochemical uranium extraction (EUE) from seawater is a very promising strategy, but its practical application is hindered by the high potential for electrochemical system, as well as the low selectivity, efficiency, and poor stability of electrode. Herein, we developed creatively a low potential strategy for persistent uranium recovery by electrochemistry-assisted in-situ regeneration of oxygen vacancies and Ti(III) active sites coupled with indirect reduction of uranium, finally achieving high selectivity, efficient and persistent uranium recovery. As-designed titanium dioxide rich in oxygen vacancies (TiO-V) electrode displayed an EUE efficiency of ∼99.

Osteocyte ferroptosis induced by ATF3/TFR1 contributes to cortical bone loss during ageing.

Cortical bone loss is intricately associated with ageing and coincides with iron accumulation. The precise role of ferroptosis, characterized by iron overload and lipid peroxidation, in senescent osteocytes remains elusive. We found that ferroptosis was a crucial mode of osteocyte death in cortical bone during ageing.

Complete mitochondrial genome data and phylogenetic analysis of Janson, 1877 (Lepidoptera: Papilionoidea: Papilionidae).

In the present study, the complete mitochondrial genome (mitogenome) of the (Lepidoptera: Papilionoidea: Papilionidae) was sequenced by next-generation sequencing method. The mitochondrial genome is a circular DNA molecule of 15,264 bp in size with 80.7% AT content, including 37 genes (13 protein-coding genes, 2 rRNA genes, and 22 tRNA genes), and a long non-coding region (Control region).

[Analysis of clinical research features and outcome indexes of traditional Chinese medicine intervention in septic kidney injury].

This study aims to systematically review the clinical features and outcome indicators in randomized controlled trial(RCT) of traditional Chinese medicine(TCM) intervention in septic kidney injury and provide a reference for optimizing clinical study design and building the core outcome set(COS) of TCM treatment of septic kidney injury. Computer searches were conducted on PubMed, Cochrane Library, EMbase, Web of Science, CNKI, Wanfang, VIP, and SinoMed to find published RCT of TCM intervention in septic kidney injury in the past five years, extract the basic characteristics, intervention measures, outcome indicators, and other data of included studies, and conduct descriptive analysis. 53 RCTs were included, and the sample size was mostly concentrated in 60-80 cases, with abdominal infection being the most common(15 articles, 83.

Review on mechanism and remediation strategies of dissolved oxygen abnormal in surface water.

Dissolved oxygen (DO) is an important index to evaluate the quality of surface water environments. In recent years, anomalies in DO level have emerged as a major contributor to the decline of surface water quality. These anomalies have triggered several ecological and environmental challenges such as biodiversity loss, the degradation of water environmental quality, intensification of eutrophication, and an exacerbation of the greenhouse effect.