A new species of the rib-degenerated loach, genus (Cypriniformes, Cobitidae), from Guangxi, China.

A new species of the genus is described based on morphological comparisons and molecular analyses from specimens of a subterranean tributary of the Hongshui River, Lingyun County, Baise City, and a cave in Jinya Township, Fengshan County, Hechi City, Guangxi, China. Both morphological and molecular data support the validity of The new species can be distinguished from congeners by the following combination of characteristics: whole body except for head and area between pectoral-fin and pelvic-fin origin sparsely covered with minute scales; barbels elongate; five or six branched pectoral-fin rays and four branched pelvic-fin rays; vertebrae 4+42. Maximum-likelihood and Bayesian-inference phylogenetic trees exhibited congruent topological structures, exhibiting high node support for the monophyly of (BPP = 1; BS = 100), which was clustered with the other congeners.

Two new hypogean species of the genus (Osteichthyes, Cypriniformes, Nemacheilidae) from Guizhou Province, Southwest China, with underestimated diversity.

Two new species of the genus from southwestern Guizhou Province, China, are described. These are Wu, Luo, Xiao & Zhou, and Lan, Liu, Zhou & Zhou, from Maoying Town, Ziyun County, Guizhou Province, China. Wu, Luo, Xiao & Zhou, is distinguished from other hypogean species of the genus by having a combination of the following characteristics: body naked, scaleless, pigmented markings on surface of body, except ventral; eyes reduced, diameter 2.

 (Cypriniformes, Cyprinidae), a new cave fish with extremely small population size from western Guizhou, China.

This study describes a new species, ., discovered within a cave located in Hongguo Town, Panzhou City, Guizhou Province, southwestern China, with the type locality in the Nanpanjiang River basin. Phylogenetic trees reconstructed based on mitochondrial genes show that the new species represents an independent evolutionary lineage with large genetic differences, 1.

A new species of (Teleostei, Cypriniformes, Xenocyprididae) from Southeast China.

is described from the Qiantang and Oujiang rivers in Zhejiang Province and a tributary of the Yangtze River adjacent to the Qiantang River. It is distinguished from congeners by the following combination of morphological features: no obvious anterior notch on the tip of the upper lip; 45-52 lateral-line scales; 18-21 pre-dorsal scales; two rows of pharyngeal teeth; a maxillary extending to or slightly beyond the vertical anterior margin of the orbit in adult males; a pectoral fin extending to the pelvic fin in adult males; nuptial tubercles on the cheeks and lower jaw of males, which are usually united basally to form a plate; uniform narrow pale pink cross-bars on trunk and two widening significantly on caudal peduncle. Its validity was also supported by its distinct Cyt gene sequence divergence from all congeners and its monophyly recovered in a Cyt gene-based phylogenetic analysis.

First description of the female and morphological variations with range extension of (Anura, Rhacophoridae).

Background: Yu, Wang, Hou, Rao and Yang, 2017 was originally described, based on 14 adult male specimens from Lengquan Village, Mengzi, Yunnan, China. So far, this species is known only from south-eastern Yunnan and information on females of this species is not available. During the field surveys in 2023, two specimens (one female and one male) were collected from central eastern Yunnan (Shilin, Kunming, Yunnan, China).

A New Species of the Blind Cave Loach Genus (Cypriniformes: Cobitidae), sp. nov., from Guangxi, China.

species are typical cave-dwelling fish, exhibiting distinctive morphological adaptations such as colorless body, lack of eyes, and reduced scales and ribs in response to their extreme cave habitats. Distinct from the recorded species, , , and , a new species, sp. nov.

Four new hypogean species of the genus (Osteichthyes, Cypriniformes, Nemacheilidae) from Guizhou Province, Southwest China, based on molecular and morphological data.

Recently described cave species of the genus have been discovered in southwestern China, suggesting that the diversity of the genus is severely underestimated and that there may be many undescribed species. In this work, four new species of the genus are described from southwestern Guizhou Province, China, namely Luo, Mao, Zhao, Xiao & Zhou, and Mao, Zhao, Yu, Xiao & Zhou, from Rongdu Town, Ceheng County, Guizhou, Yu, Luo, Lan, Xiao & Zhou, from Hongguo Town, Panzhou City, Guizhou, and Song, Luo, Lan, Zhao, Xiao & Zhou, from Xinglong Town, Anlong County, Guizhou. These four new species can be distinguished from all recognized congeners by a combination of morphological characteristics and significant genetic divergences.

, the first cavefish species of the genus (Teleostei, Balitoridae) from Guizhou Province, southwest China.

This work describes a new species, , collected from a cave at Xinglong Town, Anlong County, Guzihou, China. Phylogenetic trees reconstructed based on two mitochondrial and three nuclear genes show that the new species represents an independent evolutionary lineage with large genetic differences, 7.1%-12.

, a new species of hillstream loach (Teleostei, Cypriniformes, Gastromyzontidae) from the Ou-Jiang River, Southeast China.

, a new species, is described from the Ou-Jiang basin in Zhejiang Province, Southeast China. It is distinguished from other species of the genus by having a combination of the following characteristics: body without obvious mottling; snout length longer than postorbital length; abdominal scaleless area extending to middle of pectoral-fin base; shorter rostral barbels, the outermost pair length 112.9%-140.

Effect of Paricalcitol Combined with Cinacalcet on Calcium and Phosphorus Metabolism in Patients Receiving Maintenance Hemodialysis.

This study was designed to compare the beneficial effects of paricalcitol combined with or without cinacalcet on calcium and phosphorus metabolism in patients undergoing maintenance hemodialysis (MHD). A total of 140 patients who received MHD in our hospital from March 2021 to March 2022 were randomly divided into a control group (intravenous paricalcitol, n = 70) and a test group (intravenous paricalcitol combined with oral cinacalcet, n = 70). Clinical baseline data and relevant laboratory parameters before treatment were compared.

 (Cypriniformes, Nemacheilidae), a new species of stream fish from Guangxi, Southwest China.

In this work, a new species of the genus is described, named Yu, Luo, Lan, Xiao & Zhou, , collected from the Damingshan Mountains of the Guangxi Zhuang Autonomous Region, China. Phylogenetic trees constructed based on the mitochondrial Cyt showed that the new species represents an independent evolutionary lineage, with uncorrected genetic distances (-distance) from congeners ranging from 6.1% to 8.

 (Cypriniformes, Cyprinidae), a new species of microphthalmic hypogean fish from Guizhou, Southwest China.

is described from the Pearl River basin in Hongguo Town, Panzhou City, Guizhou Province, Southwest China. Based on the presence of the long horn-like structure on the back of the head, is assigned to the species group. is distinguished from its congeners by a combination of morphological characters: (1) presence of a single, relatively long horn-like structure on the back of the head; (2) pigmentation absent; (3) reduced eyes; (4) dorsal-fin rays, ii, 7; (5) pectoral-fin rays, i, 13; (6) anal-fin rays, iii, 5; (7) pelvic-fin rays, i, 7; (8) lateral line pores 38-49; (9) gill rakers well developed, nine on first gill arch; and (10) tip of adpressed pelvic fin not reaching anus.

Hub-collision avoidance and leaf-node options algorithm for fractal dimension and renormalization of complex networks.

The box-covering method plays a fundamental role in the fractal property recognition and renormalization analysis of complex networks. This study proposes the hub-collision avoidance and leaf-node options (HALO) algorithm. In the box sampling process, a forward sampling rule (for avoiding hub collisions) and a reverse sampling rule (for preferentially selecting leaf nodes) are determined for bidirectional network traversal to reduce the randomness of sampling.

Phylogenetic analysis of combined mitochondrial genome and 32 nuclear genes provides key insights into molecular systematics and historical biogeography of Asian warty newts of the genus (Caudata: Salamandridae).

The Chang, 1935 genus of Asian warty newts is the second most diverse genus in the family Salamandridae, currently containing 14 recognized species from northern Vietnam to southwest-central and southern China. Although species of this genus have been included in previous phylogenetic studies, the origin and interspecific relationships of the genus are still not fully resolved, especially at key nodes in the phylogeny. In this study, we sequenced mitochondrial genomes and 32 nuclear genes from 27 samples belonging to 14 species to reconstruct the interspecific phylogenetic relationships within and explore its historical biogeography in southern China.

Kinsenoside alleviates inflammation and fibrosis in experimental NASH mice by suppressing the NF-κB/NLRP3 signaling pathway.

Background: Non-alcoholic steatohepatitis (NASH) has replaced viral hepatitis as the main driver of the rising morbidity and mortality associated with cirrhosis and liver cancer worldwide, while no FDA-approved therapies are currently known. Kinsenoside (KD), naturally isolated from Anoectochilus roxburghii, possesses multiple biological activities, including lipolysis, anti-inflammation, and hepatoprotection. However, the effects of KD on NASH remain unclear.

The complete mitochondrial genome of (Cypriniformes: Gastromyzontidae).

This study determined the complete mitochondrial genome of (Cypriniformes: Gastromyzontidae) from Zhejiang, China, for the first time. The complete mitochondrial genome of was sequenced to be 16,555 bp in length. The genome contained 13 protein-coding genes, 22 transfer RNAs, two ribosomal RNAs, two central non-coding regions (the control region and the origin of light strand replication), identical to most other vertebrates.

Effectiveness of montelukast for uremic pruritus in hemodialysis patients: A protocol for systematic review and meta-analysis.

Background: Uremic pruritus (UP) is a common and tormenting symptom in end-stage renal disease patients undergoing maintenance hemodialysis. An increasing number of studies have been published in recent years to support the effectiveness of montelukast for UP. We will conduct a comprehensive systematic review and meta-analysis to evaluate effectiveness of montelukast for UP in hemodialysis patients.

(Gesneriaceae), a new species from Zhejiang Province, East China.

, a new species endemic to Zhejiang province, eastern China, is described and illustrated with photographs. The new species is morphologically similar to , and in leaf morphology, but can be easily distinguished by a combination of characters, including the shape of bracts, calyx and calyx lobes.

Newly identified viral genomes in pangolins with fatal disease.

Epizootic pathogens pose a major threat to many wildlife species, particularly in the context of rapidly changing environments. Pangolins (order Pholidota) are highly threatened mammals, in large part due to the trade in illegal wildlife. During July to August 2018 four sick wild pangolins (three and one ) exhibiting a variety of clinical symptoms were rescued by the Jinhua Wildlife Protection Station in Zhejiang province, China.

Refreshing Piezoelectrics: Distinctive Role of Manganese in Lead-Free Perovskites.

Driven by an ever-growing demand for environmentally compatible materials, the past two decades have witnessed the booming development in the field of piezoelectrics. To maximally explore the potential of lead-free piezoelectrics, chemical doping could be an effective approach, referenced from tactics adopted in lead-based piezoelectrics. Herein, we reveal the distinct role of manganese in a promising lead-free perovskite (K, Na)NbO (denoted by KNN) in comparison to that in market-dominating lead-based counterparts [Pb(Zr, Ti)O, PZT].

Predictive role of CHADS2 and CHA2DS2-VASc scores on stroke and thromboembolism in patients without atrial fibrillation: a meta-analysis.

Objective: CHA2DS2-VASc is the extension of the CHADS2 score developed by Birmingham 2009. This risk stratification schema is often used in clinical setting when considering additional risk factors for developing stroke in AF patients. However, its role in the non-AF population is unknown.

Pulse pressure as an independent predictor of stroke: a systematic review and a meta-analysis.

Background: Recent evidence suggests that pulse pressure (PP) is a strong cardiovascular diseases' risk factor. We systematically evaluated all relevant studies to determine whether PP can be used as an independent predictor of stroke and mortality.

Methods And Results: A meta-analysis was performed by searching the published literature using MEDLINE, Cochrane and Google Scholar databases up to December 15, 2015.